Cardiac CT Angiography Manual Robert Pelberg Cardiac CT Angiography Manual Second Edition Robert Pelberg The Christ Hospital Physicians Ohio Heart and Vascular Center The Lindner Center for Research and Education The Christ Hospital Cincinnati , OH USA ISBN 978-1-4471-6689-4 ISBN 978-1-4471-6690-0 (eBook) DOI 10.1007/978-1-4471-6690-0 Library of Congress Control Number: 2015941102 Springer London Heidelberg New York Dordrecht © Springer-Verlag London 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifi cally the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduc- tion on microfi lms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of pub- lication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer-Verlag London Ltd. is part of Springer Science+Business Media (www.springer.com) In loving memory of my late father, Joe Pelberg, who inspired me to be all that I could be. To my wife, Wendy, and my amazing children, Josh, Adam, and Noah, who make life worth living. Pref ace Since the publication of the first edition of this work, cardiac CT angiography (CCTA) has come a long way. It is now a mainstream, well-established cardiac diagnostic imaging modality with widespread acceptance and application. This second edition is meant to adhere to the guiding principles of the first edition while serving as a useful and up-to-date manual on the theory, performance, and application of CCTA. In particular, this work will serve you well as a useful summary of the field and an aid in the training process. It is intended to make hard-to-understand concepts easy and enjoyable by translating difficult ideas into simple terminol- ogy and phraseology. It is meant to guide you through your training process and to serve as a useful reference for those already practicing CCTA. I feel this book should accompany any CCTA laboratory. While this work maintains its form by including a complete review of concepts in general CT and in CCTA in particular (including cardiac anatomy, imaging arti- facts, and more), it also includes many useful updates, which include a more modern discussion of the technology, an updated review of radiation and radiation dosing, a review of the current appropriateness criteria and performance, inter- pretation and reporting guidelines in the field, an update on the most current performance, accuracy, and prognostic data, as well as a review of the most modern, specific CCTA clini- cal applications, including CCTA in the emergency depart- ment, transcatheter aortic valve replacement, and functional assessment of coronary stenoses including stress CCTA and vii viii Preface CT FFR. I certainly hope you enjoy this book for years to come as much as I have enjoyed writing it. CCTA is constantly evolving and improving. New research and clinical experience continue to rapidly evolve the tech- nique. I believe the information in this book to be reliable and in accord with the standards accepted at the time that the document was written. However, in view of the possibility of human error or changes in the field, I do not warrant that the information contained herein is in every respect accurate or complete, and I am not responsible for any errors or omis- sions or for the results obtained from the use of such information. Readers are encouraged to confirm the information herein with other sources. For example, and in particular, readers are advised to check the product information sheet included in the package insert of each drug and contrast agent they plan to administer to be certain that information contained in this document is accurate and that changes have not been made in the recommended dose or in the contraindications for administration. In addition, readers are encouraged to be familiar with the concepts of radiation safety. Cincinnati, OH, USA Robert Pelberg Contents 1 Concepts in Radiation and Radiation Safety . . . . . 1 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 2 Basic Principles in Computed Tomography (CT) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Basic CT Physics and Technology . . . . . . . . . . . . . . 19 The CT Scanner. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 X Ray Detectors and X Ray Beam Detection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Multislice CT (MSCT) . . . . . . . . . . . . . . . . . . . . . . . . 26 Image Reconstruction Techniques . . . . . . . . . . . . . . 30 Important CT Concepts and Terms. . . . . . . . . . . . . . 36 Convolution Filters. . . . . . . . . . . . . . . . . . . . . . . . . 36 CT Image Contrast. . . . . . . . . . . . . . . . . . . . . . . . . 36 Spatial Resolution. . . . . . . . . . . . . . . . . . . . . . . . . . 38 Temporal Resolution . . . . . . . . . . . . . . . . . . . . . . . 42 Contrast Resolution. . . . . . . . . . . . . . . . . . . . . . . . 44 Collimation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 Image Noise. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Field of View. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 Computer Screen Matrix. . . . . . . . . . . . . . . . . . . . 49 Hounsfield Units. . . . . . . . . . . . . . . . . . . . . . . . . . . 50 Windowing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 Image Axes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 Pitch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 ix