Cancers of the Skin: Proceedings of the 8th World Congress

375 Pages·2002·9.222 MB·English

by  Günter Burg (auth.), Prof. Dr. Reinhard Dummer, PD.Dr. Frank O. Nestle, Prof. Dr. Günter Burg (eds.)

Recent Results 160
in Cancer Research
Managing Editors
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Springer
Berlin
Heidelberg
New York
Barcelona
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R. Dummer F. O. Nestle G. Burg (Eds.)
Cancers of the Skin
Proceedings of the
8th World Congress
With 41 Figures and 27 Tables
Springer
Prof Dr. Reinhard Dummer
o.
PD Dr. Frank Nestle
Prof Dr. Gunter Burg
University of Zurich
Department of Dermatology
Gloriastr. 31
8091 Zurich, Switzerland
Indexed in Current Contents and Index Medicus
ISBN-13:978-3-642-63969-2 Springer-Verlag Berlin Heidelberg New York
ISSN 0080-0015
Library of Congress Cataloging-in-Publication Data
Die Deutsche Bibliothek - CIP-Einheitsaufnahme
Cancers of the skin: proceedings of the 8th world congress; with 25 tables 1 [The Eight
World Congress on Cancers of the Skin, July 18-21, 2001, Zurich, Switzerland]. R. Dum
mer ... (ed.). - Berlin; Heidelberg; New York; Barcelona; Hong Kong; London; Milan;
Paris; Tokyo: Springer, 2002
(Recent results in cancer research; 160)
ISBN-13:978-3-642-63969-2 e-ISBN-13:978-3-642-59410-6
DOl: 10.1007/978-3-642-59410-6
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Contents
1 Prevention
Public Education in Skin Cancer World-Wide 3
G. Burg
UV Protection and Skin Cancer 7
R. Dummer, T. Maier
2 UV Protection by Clothes
Role of Clothes in Sun Protection . . . . . . . . . . . . . . . . . . . . . . .. 15
T. Gambichler, P. Altmeyer, K. Hoffmann
Sun Protective Clothing: 5 Years of Experience in Australia . . . . . . .. 26
C. R. Roy, P. H. Gies, A. McLennan
European Standards for Protective Apparel Against UV Radiation 35
J. Laperre, F. Foubert
American Standards for UV-Protective Textiles . . . . . . . . . . . . . . .. 42
K.L. Hatch
Activities of (IE DIV-6 (Photobiology and Photochemistry)
in UV Protection and Clothing . . . . . . . . . . . . . . . . . . . . . . . . .. 48
J. P. Cesarini
Comparison of Methods:
Determination of UV Protection of Clothing ......•...•...... 55
T. Gambichler, P. Altmeyer, K. Hoffmann
VI Contents
Improving UV Protection by Clothing - Recent Developments . . . . .. 62
U. Osterwalder, H. Rohwer
Dress up for Sun Protection/Creation of Public Awareness 70
P. Cesarini
3 Melanoma
Pathogenesis
The Precursors of Malignant Melanoma ..•................. 75
A. N. Crowson, C. M. Magro, I. Sanchez-Carpintero,
M. C. Mihm Jr.
Interferon-a Sensitivity in Melanoma Cells:
Detection of Potential Response Marker Genes .......... 85
U. Certa, M. Seiler, E. Padovan, G. C. Spagnoli
Molecular Cytogenetics as a Diagnostic Tool
for Typing Melanocytic Tumors ......................... 92
B.c. Bastian
Loss of Heterozygosity and Microsatellite Instability
in Acquired Melanocytic Nevi: Towards a Molecular Definition
of the Dysplastic Nevus .... . . . . . . . . . . . . . . . . . . . . . . . . .. 100
A. Rilbben, I. Bogdan, E. I. GrujJendorf-Conen,
G. Burg, R. Boni
Epidemiology
The Changing Incidence and Mortality of Melanoma in Australia . . .. 113
R. Marks
Diagnostic
Why Is Epiluminescence Microscopy Important? . . . . . . . . . . . . . .. 125
K. Wolff
Sentinel Node Biopsy: Not Only a Staging Tool? .............. 133
R. Essner, A. J. Cochran
Therapy
The Impact of Surgery on the Course of Melanoma ............ 151
F. J. Lejeune
Contents VII
Perspectives of Pegylated Interferon Use in Dermatological Oncology 158
H. Pehamberger
Dendritic Cell Vaccination for the Treatment of Skin Cancer ....•.• 165
o.
F. Nestle
Gene-based Immunotherapy of Skin Cancers . . . . . . . . . . . . . . . .. 170
Y. Sun, D. Schadendorf
Cytokine-Fusion-Protein-Treatment ....................... 185
D. Schrama, P. thor Straten, E.-B. Bracker,
R. A. Reisfeld, J. c. Becker
Cytotoxic T-cell Induction in Metastatic Melanoma Patients
Undergoing Recombinant Vaccinia Virus-based
Immuno-gene Therapy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 195
G. C. Spagnoli, P. Zajac, W. R. Marti, D. Oertli,
E. Padovan, C. Noppen, T. Kocher, M. Adamina,
M. Heberer
Follow-up
A Rational Approach to the Follow-up of Melanoma Patients ...... 205
C. Garbe
4 Epithelial Skin Tumors
Therapy
Micrographic Surgery of Basal Cell Carcinomas of the Head ....... 219
B. Woerle, M. Heckmann, B. Konz
Repair of Cutaneous Defects After Skin Cancer Surgery 225
M. Hess Schmid, C. Meuli-Simmen, J. Hafner
Radiotherapy of Skin Tumors. . . . . . . . . . . . . . . . . . . . . . . . . .. 234
R. Panizzon
Photodynamic Therapy and Fluorescence Diagnosis of Skin Cancers .. 240
R. M. Szeimies, M. Landthaler
Intralesional Interferon in Basal Cell Carcinoma: How Does It Work? .• 246
S. Buchner, M. Wernli, F. Bachmann, T. Harr, P. Erb
VIII Contents
Epithelial Malignancies in Organ Transplant Patients:
Clinical Presentation and New Methods of Treatment ......•.... 251
E. Stockfleth, C. Ulrich, T. Meyer, E. Chris top hers
New Treatment Modalities for Basal Cell Carcinoma 259
E. Stockfleth, W. Sterry
5 Lymphoma
Pathogenesis
From Inflammation to Neoplasia: New Concepts in the Pathogenesis
of Cutaneous Lymphomas ............................ 271
G. Burg, W. Kempf, A. Haeffner, U. Dobbeling,
F. O. Nestle, R. Boni, M. Kadin, R. Dummer
Clinical Presentations
Cutaneous Lymphomas and Pseudo lymphomas:
Newly Described Entities ............................. 283
D. Kazakov, G. Burg, R. Dummer, W. Kempf
Clinical Aspects and Pathology of Primary Cutaneous B-Cell
Lymphomas ..................................... 294
H. Kerl, R. Fink-Puches, L. Cerroni
Diagnosis
Modern Diagnosis of Cutaneous Lymphoma •..........•..... 303
B. Giannotti, N. Pimpinelli
Therapy
Treatment of Cutaneous T Cell Lymphoma: 2001 .............. 309
E.C. Vonderheid
New Biologic Agents for the Treatment
of Cutaneous T-Cell Lymphoma ......................... 321
C. C. Vittorio, J. M. Junkins-Hopkins, M. Shapiro,
M. Wysocka, M. H. Zaki, L. E. French, A. H. Rook
Contents IX
6 Mesenchymal Tumors
Etiology and Pathogenesis of Kaposi's Sarcoma ............... 331
B. Nickoloff, K. E. Foreman
Connective Tissue Tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . .. 343
B. Zeiger
7 Psychosocial Aspects
How to Identify Patients in Need of Psychological Intervention ..... 351
G. Strittmatter, M. Tilkorn, R. Mawick
Psychotherapeutic Interventions in Melanoma Patients .......... 362
W. Sollner, R. Gross, S. Maislinger
Subject Index ................................... 371
Principal Authors
Boris C. Bastian, MD Ulrich Certa, MD
Comprehensive Cancer Center F. Hoffmann-La Roche Ltd.
and Department Pharmaceuticals Division
of Dermatology Bldg. 93/610
and Pathology 4070 Basel, Switzerland
University of California
2340 Sutter Street Jean-Pierre Cesarini, MD
San Francisco, CA 94115, USA CIE Division 6
Laboratoire de Recherche
Jurgen C. Becker, MD sur les Tumeurs
Department of Dermatology de la Peau Humaine
Julius Maximilians University Fondation Adolphe
Jo sef-Schneider-Str. 2 de Rothschild
97080 Wurzburg, Germany 25, rue Manin
75019 Paris, France
Stanislaw Buchner, MD
Department of Dermatology Pierre Cesarini
University of Basel Association Securite Solaire
Kantonsspital (WHO Collaborating Center)
Peters graben 4 25, rue Manin
4031 Basel, Switzerland 75019 Paris, France
Gunter Burg, MD Reinhard Dummer, MD
Department of Dermatology Department of Dermatology
University Hospital of Zurich University Hospital of Zurich
Gloriastr. 31 Gloriastr. 31
8091 Zurich, Switzerland 8091 Zurich, Switzerland