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Cancer 2000: Vol 89 Index PDF

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Subject Index—Volume 89 . 1, July 1, pp. 1-228 . 8, October 15, pp. 1647-1868 . 2, July 15, pp. 229-474 . 9, November 1, pp. 1869-2024 . 3, August 1, pp. 475-714 . 10, November 15, pp. 2025-2144 . 4, August 15, pp. 715-938 . 11, December 1, pp. 2145-2326 . 5, September 1, pp. 939-1180 . 11, December 1, Supplement, pp. 2327- . 6, September 15, pp. 1181-1412 2514 . 7, October 1, pp. 1413-1646 No. 12, December 15, pp. 2515-2686 A anti-CD20, for cutaneous B-cell lymphoma, 1835 Acquired immunodeficiency syndrome, non-Hodgkin’s monoclonal lymphoma in, stem cell transplant for, 680 IMC-C225, inhibition of pancreatic tumor growth by, Acute leukemia. See Leukemia 74 Adenocarcinoma. See specific sites for prostate cancer, 1329 Africa, Ivory Coast, cancer incidence in, 653 single chain Fv fragment of, in immunofluorescent African Americans tumor localization, 1134 bladder cancer in, stage at diagnosis of, 1349 p53, in esophageal cancer, 1677 breast cancer outcome in, 2202 Anti-CD20 antibody, for cutaneous B-cell lymphoma, AIDS, non-Hodgkin’s lymphoma in, stem cell transplant 1835 for, 680 Antiemetics, ganisetron vs. ondansetron as, 2301 Alcohol use/abuse Antiestrogen ICI 182,780 (Faslodex), for breast cancer, gastric cancer survival and, 1205 817 hepatitis C-related hepatocellular carcinoma and, 53 Antigen(s). See also specific antigens Alliance for Lung Cancer Advocacy, Support, and Educa- CA 19-9, in pancreatic cancer, vs. tissue polypeptide tion (ALCASE), 2510 specific antigen, 83 Alternative therapies, compliance with standard treat- CA 125, in fallopian tube cancer, prognosis and, 1555 ment and, 873 carcinoembryonic Alveolar proteinosis, in BCR/ABL negative chronic my- in colorectal cancer, prognosis and, 970 eloid leukemia, neutrophil hyperfunction in, 561 in immunoscintigraphy, for breast cancer, 104 Amenorrhea, after chemotherapy, for osteosarcoma, 1961 isolated elevation of, in colorectal cancer, radioim- American Cancer Society, prospective cohort study of munoguided surgery for, 1692 thyroid cancer, 202 Ki-67 American College of Surgeons Commission on Cancer, in breast cancer prospective cohort study of thyroid cancer, 202 chemotherapy response and, 2145 American Indians, stage at diagnosis, treatment, and sur- prognosis and, 1748 vival in, 181 in Ewing’s sarcoma, prognosis and, 783 9-Aminocamptothecin, for metastatic colorectal cancer, in nonsmall cell lung cancer, postoperative survival 1699 and, 1457 Analgesia consultation for, outcome of, 920 p21 in bladder cancer, prognosis and, 619 morphine in hospice setting and, 220 (letter) Angiogenesis, inhibition of in cervical squamous cell carcinoma, 1300 gene therapy for, 1181 in Ewing’s sarcoma, prognosis and, 783 p27*'P', in gastric cancer, prognosis and, 1684, 2247 for prostate cancer, 1329 Angiosarcoma, schwannoma with, 1577 p53. See p53 Angiotrophic large cell lymphoma, superior vena cava proliferating cell nuclear syndrome and, 2515 in congenital sacrococcygeal teratoma, 932 Antiangiogenic therapy in verrucous oral cancer, 2597 gene therapy in, 1181 prostate specific for prostate cancer, 1181, 1329 adjusted for transition zone volume, 842 Antibody(ies) after radical prostatectomy, 1810 bmiv CANCER December 15, 2000 / Volume 89 / Number 12 prostate specific membrane, monoclonal antibodies to, Benign central neurocytoma, 1111 for prostate cancer, 1329 Bile ducts, noninvasive/minimally invasive papillary car- tissue polypeptide specific, in pancreatic cancer, 83 cinoma of, 508 Antimicrotubule drugs, for hepatoma, 983 Biliary obstruction, from gastric cancer, chemoradiation Antioxidant enzymes, in prostatic intraepithelial neopla- for, 29 sia and cancer, 123 Biliary papillomatosis, intraluminal iridium-192 for, 69 Apoptosis, in breast cancer, chemotherapy response and, Biologic therapy, for prostate cancer, 1329 2145 Biomarkers. See Tumor markers Appalachia, breast and cervical cancer mortality in, 1593 Biopsy Argyrophilic cell hyperplasia, duodenal carcinoids and, endometrial, diagnostic yield of, 1765 963 image-guided core-needle, in lymphoma, 647 Arterial embolization, with arterial infusion chemother- lymph node apy, for pancreatic cancer, 303 image-guided core-needle, in Hodgkin’s disease, 647 Arterial infusion chemotherapy, for pancreatic cancer, sentinel node 303 in breast cancer Ascorbic acid, accumulation of, in squamous cell carci- computer simulations for, 2187 noma, 17] false negative, after preoperative chemotherapy, Asian Americans, screening for breast and cervical cancer 2187 in, 696 in melanoma Asians frozen section analysis of, 1720 breast cancer in, BRCA/ mutation and, 811 patient selection for, 453 nasal-type natural killer/T-cell and natural killer pre- percutaneous needle, of musculoskeletal masses, 2677 cursor lymphoma in, 2106 prostate in U.S., gastric cancer in, clinical features and survival detailed mapping of disease foci in, 1800 in, 1183 postbrachytherapy, disease and treatment effects on, Assessment tool(s) 1829 McGill Quality of Life Questionnaire, 1854 single microscopic focus on, postoperative outcome M.D. Anderson Symptom Inventory, 1634 and, 1810 for symptom distress, 1634 Bipolar symptoms, interferon-alpha-2b and, 356 Astrocytoma, pathologic classification of, 1569 Bisphosphonates, for skeletal complications, in breast Auriculotemporal syndrome, botulinum toxin for, 1659 cancer, 363 Australia, melanoma in, time trends of, 1269 Blacks Avascular necrosis of femoral head, in interferon-treated bladder cancer in, stage at diagnosis of, 1349 chronic myeloid leukemia, 1482 breast cancer outcome in, 2202 Bladder cancer B chemoradiotherapy for, 1089 B7 molecules, T-cell proliferation and, in B-cell chronic management and outcome in, in Canada, population- lymphoproliferative disorders, 1259 based study of, 142 Basal cell carcinoma, clustering of, 1012 p21, p53 and mdm2 in, prognosis and, 619 B-cell chronic lymphocytic leukemia, CD44 and intercel- smoking and, 630 lular adhesion molecule-1 in, during interferon stage at diagnosis of, race and, 1349 therapy, 1474 Blastoma, pleuropulmonary, management and prognosis B-cell chronic lymphoproliferative disorders, T-cell pro- of, 1396 liferation in, B7 molecules and, 1259 Blood tests, fecal occult, guaiac vs. immunochemical, B-cell lymphoma sensitivity of, 46 cutaneous Body mass index, breast cancer risk and, 369 anti-CD20 antibody for, 1835 Body weight, breast cancer risk and, 369 central nervous system involvement in, 913 Bone, myogenic tumors of, post-transplant, Epstein-Barr telomerase activity in, 445 virus in, 467 bel-2 Bone disease, in metastatic breast cancer, predictors of, in breast cancer, chemotherapy response and, 2145 363 in renal cell carcinoma, DNA content and, 1065 Bone marrow transplantation BCNU, resistance to, transforming growth factor-B1- for chronic myeloid leukemia, in younger patients, binding protein and, 850 1647 Benign breast disease for HIV-associated non-Hodgkin’s lymphoma, 680 cancer risk with hormone replacement therapy and, Bone metastasis 2046 in metastatic breast cancer, predictors of, 363 relaxin-like factor in, 2161 in soft tissue sarcoma, routine scintigraphy for, 1726 Subject Index—Volume 89 bmv Bone resorption, in oral cancer, interleukin-6 enhance- lobular, hormone replacement therapy and, 1867 (let- ment of, 1966 ter) Bone scintigraphy, in soft tissue sarcoma staging, 1726 lymphatic mapping in, 236 Botulinum toxin, for Frey syndrome, 1659 lymph node metastasis in Brachytherapy. See also Radiation therapy computer simulations of, 2527 with intraluminal iridium-192, for biliary papillomato- sentinel vs. nonsentinel node, 574 sis, 69 mortality in, in Appalachian women, 1593 for prostate cancer, 135 node-negative, DNA content of, prognostic value of, effects of on biopsy results, 1829 1748 prostatourethral-rectal fistula after, 2085 pegylated liposomal doxorubicin (Doxil) for, 1037 Brain. See also under Cerebral persistent impact of on functional health status, 2176 Brain metastasis postmastectomy irradiation for, axillary node extran- from prostate cancer, 706 (letter) odal soft tissue extension and, 223 (ietter) from unknown primary, 1095 psychosocial group intervention for, in Japan, 1026 Brain stem tumors, pathologic classification of, 1569 refractory, paclitaxel for, 2195 Brain tumors relaxin-like factor in, 2161 brain stem, pathologic classification of, 1569 screening for glioblastoma multiforme, trofosfamide and etoposide in Asian American and Pacific Islanders, 696 for, 2131 CEA immunoscintigraphy with, 104 glioma as second primary, 1999 sentinel/completion lymphadenectomy for, 236 carmustine resistance in, transforming growth fac- tor-81-binding protein and, 850 sentinel node biopsy in, false negative, after preopera- venous thromboembolism in, 640 tive chemotherapy, 2187 serum CYFRA 21-1 in, 1285 BRCAI heterozygotes, premalignant ovarian changes in, skeletal complications in, predictors of, 363 383 survival in, in U.S. vs. Europe, 893 BRCAI mutation, breast cancer and, in Asian women, 811 tamoxifen for, uterine cancer surveillance after, 800 BRCA2, allelic imbalance at, in nonsmall cell lung cancer, treatment of 1933 less than definitive, recurrence and mortality and, Breast 1739 cystosarcoma phyllodes of, treatment of, 1502 in older women, 561 fiberoptic ductoscopy of, 1512 weight, body mass index and tissue density and, 369 tissue density of, cancer risk and, 369 Breast conserving surgery, in older women, 561 Breast cancer Breast disease, benign advanced, doxorubicin and paclitaxel for, 2169 cancer risk with hormone replacement therapy and, axillary tumor free nodes in, number of, prognosis and, 2046 213 (letter) relaxin-like factor in, 2161 biopsy in, percutaneous, imaging-histologic discor- Bronchoscopy, fluorescence, in lung cancer detection, dance in, 2538 2468 BRCAI mutation and, in Asian women, 811 Bryostatin-1, for metastatic renal cell carcinoma, 615 CEA immunoscintigraphy for, 104 chemotherapy response in, apoptosis and cellular pro- liferation and, 2145 C COX-2 in, 2637 Ca** /calmodulin-dependent protein kinase IV, in hepa- cyclophosphamide-doxorubicin vs. cyclophospha- tocellular carcinoma, 1910 mide-methotrexate-5-fluorouracil for, 2521 CA 19-9, in pancreatic cancer, vs. tissue polypeptide spe- ductal in situ cific antigen, 83 HER-2/neu amplification and p53 mutation in, 2153 CA 125, in fallopian tube cancer, prognosis and, 1555 local recurrence of, outcome in and factors affecting, Cadherins 2323 (letter) in cervical cancer, 2053 estrogen receptor-a/8 MRNA expression in, PCR anal- in ulcerative colitis—associated colorectal cancer, 733 ysis of, 1732 Calcium channel blockers, cancer risk and mortality with, gastric metastasis in, presentation, endoscopic features 165 and treatment of, 2214 CaM-kinase IV, in hepatocellular carcinoma, 1910 hereditary prostate cancer and, 1315 Canada hormone replacement therapy and, in benign breast bladder cancer management and outcome in, popula- disease, 20246 tion-based study of, 142 ICI 182,780 (Faslodex) for, 817 cancer incidence rates and socioeconomic status in, vs. intratumoral injection of dendritic cells for, 2646 in U.S., 901 bmvi CANCER December 15, 2000 / Volume 89 / Number 12 Cancer incidence Cerebral metastasis socioeconomic status and, in Canada vs. U.S., 901 from prostate cancer, 706 (letter) in very elderly, in Netherlands, 1121 from unknown primary, 1095 Cancer of the Liver Italian Program (CLIP) score, 2266 Cervical cancer Cancer of unknown primary site, paclitaxel-carboplatin- cadherins in, 2053 etoposide for, 2655 early invasive adenocarcinoma, histopathology of, 1048 Cancer pain consultation, outcome of, 920 in Ivory Coast, 653 Cancer patient, personal account of, 229 mortality in, in Appalachian women, 1593 Cancer risk, with calcium channel blockers, 165 non-squamous cell, increasing incidence of, in Nor- Cancer survival, in U.S. vs. Europe, 893 way, 1291 Cancer treatment, compliance with, use of alternative radiotherapy for, high growth fraction at 9 Gy in, prog- therapies and, 873 nosis and, 1526 Carboplatin screening for for cancer of unknown primary site, 2655 in Asian American and Pacific Islanders, 696 for metastatic retinoblastoma, 2117 direct visual inspection vs. Pap smear for, 826 with radiotherapy in resource-poor settings, 826 for head and neck cancer, 2099 squamous cell, p53 and p21 in, 1300 for nonsmall cell lung cancer, 534 survival in, in U.S. vs. Europe, 893 Carcinoembryonic antigen, isolated elevation of, in colo- Cervical dysplasia, folate, homocysteine, vitamin B,. and rectal cancer, radioimmunoguided surgery for, cysteine as markers for, 376 1692 Cervix, direct visual inspection of, vs. Pap smear, 826 Carcinoembryonic antigen immunoscintigraphy, for c-ets], in endometrial cancer, 2059 breast cancer, 104 Chemoembolization Carcinoembryonic antigen mRNA, in colorectal cancer, hepatic arterial prognosis and, 970 with percutaneous microwave coagulation therapy, Carcinoids, multiple duodenal, 963 1245 Carmustine, resistance to, transforming growth factor- preoperative, in hepatocellular carcinoma, 2606 61-binding protein and, 850 for pancreatic cancer, 303 Carotid body paraganglioma, vs. schwannoma with an- Chemoradiotherapy. See also Chemotherapy; Radiation giosarcoma, 1577 therapy Cartilaginous tumors, connective tissue growth factor in, for bladder cancer, 1089 1466 for cerebral lymphoma, 1359 Catalase, in prostatic intraepithelial neoplasia and can- for esophageal cancer, 946, 2144 (erratum) cer, 123 for extrahepatic biliary tract recurrence of gastric can- Catenin, in ulcerative colitis—associated colorectal can- ceive cer, 733 for head and neck cancer, 2099 Cathepsin B for nonsmall cell lung cancer, 534 in chondrosarcoma, 995 for oral/oropharyngeal cancer, 939 in lymph nodes, in nonsmall lung cancer, prognosis for pancreatic cancer, vs. resection, as initial therapy, and, 2282 314 Cathepsins, in early stage gastric cancer, 482 for pediatric nasopharyngeal cancer, 690 CD44 for retinoblastoma, with metastasis, 2117 in non-Hodgkin’s lymphoma and chronic lymphocytic Chemosensitivity testing, for hepatic arterial infusion leukemia, during interferon therapy, 1474 chemotherapy, 288 in ulcerative colitis-associated colorectal cancer, 733 Chemotherapy. See also specific drugs Cell adhesion molecules arterial infusion, for pancreatic cancer, 303 in non-Hodgkin’s lymphoma and B-cell chronic lym- for breast cancer, 817, 1037 phocytic leukemia, during interferon therapy, in advanced disease, 2169 1474 in older women, 561 in ulcerative colitis—-associated colorectal cancer, 733 in refractory disease, 2195 Cellular proteases, in chondrosarcoma, 995 response to, apoptosis and cellular proliferation and, Central Europe, melanoma in, time trends of, 1269 2145 Central nervous system involvement, in cutaneous B-cell for cancer of unknown primary site, 2655 lymphoma, 913 for colorectal cancer, 1699 Central neurocytoma, 1111 for fallopian tube cancer, 2076 c-erbB-3, in verrucous oral cancer, 2597 for glioblastoma multiforme, 2131 Cerebral lymphoma, radiation therapy with/without che- for gynecologic cancer, quality of life and, 1402 motherapy for, 1359 for head and neck cancer, 2587 Subject Index—Volume 89 bmvii hepatic arterial infusion, thymidylate synthase quanti- CHOP regimen, for cerebral lymphoma, with radiation tation and in vitro chemosensitivity testing for, therapy, 1359 288 Choriocarcinoma, cyclin E in, 673 for hepatoblastoma presenting with lung metastasis, Chromosome 3p23, loss of heterozygosity at, in colorectal 1845 cancer, prognosis and, 1220 for hepatocellular carcinoma, 750 Chronic duodenitis, multiple carcinoids and endocrine for hepatoma, 983 cell micronests in, 963 for lung cancer, 89, 516, 543, 750, 763, 769, 774, 1714 Chronic hepatitis C in elderly, 328, 1953 hepatocellular carcinoma and, incidence-related fac- in induction therapy, 1946 tors in, 53 in metastatic disease, 2622 transforming growth factor-a mRNA in, 977 p53 mutations and, 769 Chronic leukemia. See Leukemia with radiotherapy, 534 Chronic lymphoproliferative disorders, B-cell, T-cell pro- for maxillary sinus cancer, 1925 liferation in, B7 molecules and, 1259 for melanoma, with interferon-a, 2630 Cigarette smoking. See Smoking nausea and vomiting in, ganisetron vs. ondansetron Cisplatin for, 2301 for esophageal cancer, with radiation therapy, 946 for neuroblastoma, with granulocyte-colony stimulat- for hepatoblastoma presenting with lung metastasis, ing factor, 2122 1845 for lung cancer for osteosarcoma, reproductive function after, 1961 in elderly, 1953 for ovarian cancer, in Stage III/IV disease, 1547 with gemcitabine, 1714 for pancreatic cancer, 1706 in induction therapy, 1946 patient’s experience of, 229 in metastatic disease, 2622 for peritoneal mesothelioma, 1279 with paclitaxel and ifosfamide, 774 pharmacokinetic modulating, for hepatic colorectal for melanoma, with interferon-a, 2630 metastasis, 1228 for metastatic retinoblastoma, 2117 preoperative, for oral/oropharyngeal cancer, with con- for neuroblastoma, with granulocyte-colony stimulat- current chemoradiotherapy, 939 ing factor, 2122 for prostate cancer, 1824 for ovarian cancer, 1547 in weekly 1-hour infusion, 431, 1412 (erratum) for pancreatic cancer, arterial infusion of, 303 with radiotherapy. See Chemoradiotherapy for peritoneal mesothelioma, 1279 reduced efficacy of, after pneumoperitoneum, 262 for soft tissue sarcoma, 177 for retinoblastoma, with metastasis, 2117 CLIP score, 2266 for soft tissue sarcoma, 177 c-MYC,in nodular melanoma, 97 Chest radiography Colorectal cancer in lung cancer screening. See Lung cancer, screening carcinoembryonic antigen mRNA in, prognosis and, for 970 radiation exposure in, 2457 classification of by tumor edge morphology, 1901 Children. See also specific cancers COX-2 in, 2637 glioblastoma multiforme in, trofosfamide and etopo- familial, Swedish cohort study of, 741 side for, 2131 5-fluorouracil for, small intestinal toxicity of, 711 (let- leukemia in. See Leukemia ter) lymphoma in, pesticide exposure and, 2315 guaiac vs. insmunochemical occult blood test for, sen- metastatic retinoblastoma in, chemoradiotherapy for, sitivity of, 46 ZUE7 hepatic metastasis in nasopharyngeal cancer in, chemoradiotherapy for, 680 blood flow in, 1236 neuroblastoma in, granulocyte-colony stimulating fac- distribution of, 285 tor with chemotherapy for, 2122 fibrous pseudocapsule of, 257 salivary gland tumors in, Epstein-Barr virus in, 463 microwave coagulation therapy for, 276 Chinese. See also Asians pharmacokinetic modulating chemotherapy for, Chinese staging system, for nasopharyngeal cancer, vs. 1228 UICC system, 242 tumor thickness and, 35 Chondroma, connective tissue growth factor in, 1466 vascular endothelial growth factor and, 488 Chondrosarcoma with high-frequency microsatellite instability, clinico- cathepsin B in, 995 pathology of, 2025 connective tissue growth factor in, 1466 loss of heterozygosity at 3p23 in, prognosis and, 1220 urokinase plasminogen activator in, 995 metastatic, 9-aminocamptothecin for, 1699 bmviii CANCER December 15, 2000 / Volume 89 / Number 12 offspring of women with, lymphoma risk in, 741 Cystectomy, for bladder cancer, population-based study paclitaxel radiosensitizing effect in, p53 and, 1893 of, 142 radioimmunoguided surgery for, 1692 Cysteine, as cervical dysplasia marker, 376 recurrent, with isolated CEA elevation, radioimmu- Cysteine proteases, in early stage gastric cancer, 482 noguided surgery for, 1692 Cystosarcoma phyllodes of breast, treatment of, 1502 survival in, in U.S. vs. Europe, 893 Czechoslovakia, lung cancer screening in, 2363 tumor thickness in, prognosis and, 35 ulcerative colitis—associated, cell adhesion molecules D in, 733 D13S171, allelic imbalance at, in nonsmall cell lung can- Community income, cancer incidence and, in Canada vs. cer, 1933 US., 901 Dacarbazine, with interferon-a, for melanoma, 2630 Complementary medicine, compliance with standard Deep vein thrombosis, gliomas and, 640 treatment and, 873 Deleted colon carcinoma, in ulcerative colitis—associated Compliance, with standard treatment, use of alternative colorectal cancer, 733 therapies and, 873 Delirium, in advanced cancer, prognostic impact of, 1145 Computed tomography Dendritic cells, intratumoral injection of, 2646 in Hodgkin’s disease, correlation of with lymphangiog- Dendritic cell sarcoma, of neck, 664 raphy and Ga-67 SPECT, 1371 Depression in lung cancer screening, 2457, 2474. See also Lung interferon-alpha-2b and, 356 cancer, screening for after successfully treated lung cancer, 1172 in Japan, 2485 Developing countries. See also specific countries radiation exposure in, 2457 cost-effective early detection programs in, 475 in ovarian cancer, in surgical outcome prediction, 1532 Dexamethasone, low-dose oral, for prostate cancer, 2570 in pancreatic cancer, cost analysis for, 1917 Diet Computer simulations, of lymph node metastasis, in as cervical dysplasia marker, 376 breast cancer, 2527 gastric cancer survival and, 1205 Congenital sacrococcygeal teratoma, DNA ploidy in, 932 DNA content Connective tissue growth factor, in cartilaginous tumors, of breast cancer, prognostic value of, 1748 1466 of colorectal cancer, with high-frequency microsatellite Consultation, cancer pain, outcome of, 920 instability, 2025 Counseling, for breast cancer patients, in Japan, 1026 of congenital sacrococcygeal teratoma, 932 COX-2 of gastric lymphoma, 12 in prostate cancer, 589 of renal cell carcinoma, p53 and bcl-2 and, 1065 in pulmonary, colonic and mammary tumors, 2637 Docetaxel Cutaneous B-cell lymphoma for hepatoma, 983 anti-CD20 antibody for, 1835 lymphopenia and, 1380 for nonsmall cell lung cancer, 516 central nervous system involvement in, 913 weekly administration of, in elderly, 328 Cutaneous lymphoma, interferon-a for, 1603 with paclitaxel, weekly administration of, 2309 Cy5.5 complex, in immunofluorescent tumor localiza- Doxil, for breast cancer, 1037 tion, 1134 Doxorubicin Cyclin-dependent kinases, in gastric cancer, prognosis for breast cancer, 2169 and, 2247 with cyclophosphamide, 2521 Cyclin E, in gestational trophoblastic disease, 673 pegylated liposomal, 1037 Cyclooxygenase-2 for cerebral lymphoma, with radiation therapy, 1359 in prostate cancer, 589 for hepatoblastoma presenting with lung metastasis, in pulmonary, colonic and mammary tumors, 2637 1845 Cyclophosphamide for neuroblastoma, with granulocyte-colony stimulat- for breast cancer ing factor, 2122 with doxorubicin, 2521 for peritoneal mesothelioma, 1279 with methotrexate and 5-fluorouracil, 2521 Ductal carcinoma in situ. See also Breast cancer for cerebral lymphoma, with radiation therapy, 1359 HER-2/neu amplification and p53 mutation in, 2153 for metastatic retinoblastoma, 2117 local recurrence of, outcome in and factors affecting, for neuroblastoma, with granulocyte-colony stimulat- 2323 (letter) ing factor, 2122 Ductoscopy, fiberoptic, for nipple discharge, 1512 CYFRA 21-1 Duodenal carcinoids, endocrine cell micronests and, 963 in breast cancer, 1285 Duodenitis, chronic, multiple carcinoids and endocrine in esophageal cancer, 1413 cell micronests in, 963 Subject Index—Volume 89 bmix E CYFRA 21-1 in, 1413 fragile histidine triad gene in, 5 Early Lung Cancer Action Project, 2474 initial lymph node metastasis in, localization of, 1869 E-cadherin, in ulcerative colitis—associated colorectal invasiveness of, Ets-1 and, 1670 cancer, 733 serum p53 antibody in, 1677 Elderly squamous cell age limits for, in non-Hodgkin’s lymphoma, 2667 KAI1/CD82 in, 955 breast cancer in, treatment of, 561 neoadjuvant chemoradiotherapy for, 946, 2144 (erra- cancer incidence in, in Netherlands, 1121 tum) nonsmall cell lung cancer in, chemotherapy for, 328, superficial, ductal involvement in, 248 1953 Esophagogastric junction adenocarcinoma, lymph node Embolization micrometastasis and tumor cell microinvolve- hepatic arterial ment in, 1874 with percutaneous microwave coagulation therapy, Estramustine, for prostate cancer, 1824 1245 Estrogen receptor-a/8 mRNA expression, in breast can- preoperative, 2606 cer, PCR analysis of, 1732 transcatheter arterial, with arterial infusion chemo- Estrogen replacement therapy therapy, for pancreatic cancer, 303 in benign breast disease, cancer risk and, 2046 Emotional status lobular breast cancer and, 1867 (letter) of breast cancer patients Etoposide in Japan, 1026 for cancer of unknown primary site, 2655 persistent changes in, 2176 for glioblastoma multiforme, 2131 depression after successfully treated lung cancer, 1172 for metastatic retinoblastoma, 2117 in gynecologic cancer, with extensive chemotherapy, for neuroblastoma, with granulocyte-colony stimulat- 1402 ing factor, 2122 personal account of, 229 for nonsmall cell lung cancer in prostate cancer, before/after radiation therapy, 1322 in elderly, 1953 in successfully treated lung cancer, 1172 in induction therapy, 1946 Enchondroma, connective tissue growth factor in, 1466 with oral administration, 543 Endocrine cell micronests, in chronic duodenitis, 963 for soft tissue sarcoma, 177 Endometrial cancer Ets-1 c-ets] in, 2059 in esophageal cancer, tumor invasiveness and, 1670 microsatellite instability in in meningioma, 2292 analysis at 10q25-q26 and, 1773 Europe. See also specific countries clinical significance of, 1758 cancer survival in, vs. in U.S., 893 surveillance for, in tamoxifen-treated breast cancer Ewing’s sarcoma INK4A deletion in, prognosis and, 783 survivors, 800 p53 in, prognosis and, 783 survival in, in U.S. vs. Europe, 893 Extrahepatic bile ducts, noninvasive/minimally invasive tissue sampling in, diagnostic yield of, 1765 . papillary carcinoma of, 508 Endometrial sampling, diagnostic yield of, 1765 Extremity osteosarcoma, chemotherapy for, reproductive Endostatin, in antiangiogenic gene therapy, 1181 function after, 1961 Enzymes, antioxidant, in prostatic intraepithelial neopla- sia and cancer, 123 Epidermal growth factor, salivary, mucositis and, in oro- F pharyngeal radiation therapy, 2258 Fallopian tube cancer Epirubicin CA 125 in, prognosis and, 1555 for nonsmall cell lung cancer, 89 treatment and prognosis in, 2076 for ovarian cancer, 1547 Familial medullary thyroid carcinoma syndrome, RET Eppendorf pO. measurements, in prostate cancer, stage mutation carriers of, thyroidectomy for, 863 and patient age and, 2018 Familial prostate cancer, breast and gastric cancer and, Epstein-Barr virus 3315 in pediatric salivary gland tumors, 463 Fas ligand, circulating soluble, in gastric cancer, 2560 in post-transplant myogenic tumors of bone, 467 Faslodex, for breast cancer, 817 ERBB-2 in ovarian tissue, in BRCA/ heterozygotes, 383 Fatigue, in prostate cancer, before/after radiation ther- Errata, 473, 1412, 2144 apy, 1322 Esophageal cancer FDG positron emission tomography, in melanoma, 1019 adenocarcinoma, lymph node micrometastasis and tu- Fecal occult blood tests, guaiac vs. immunochemical, mor cell microinvolvement in, 1874 sensitivity of, 46 bmx CANCER December 15, 2000 / Volume 89 / Number 12 Femoral head, avascular necrosis of, in interferon-treated Gallium-67 SPECT, in Hodgkin’s disease, correlation of chronic myeloid leukemia, 1482 with lymphangiography and CT, 1371 Fertility Ganglioneuroblastoma, nodular, prognostic classification after chemotherapy, for osteosarcoma, 1961 of, 1150 preservation of, for ovarian germ cell tumors, 391 Ganisetron, for chemotherapy-induced nausea and vom- 'SF-fluoro-2-deoxy-D-glucose PET, delayed, in pancre- iting, 2301 atic cancer, 2547 Gastrectomny FHIT, in esophageal cancer, 5 early and late recurrence after, 255 Fiberoptic ductoscopy, for nipple discharge, 1512 with prophylactic radical lymphadenectomy, 1425 Fibrillary astrocytoma, pathologic classification of, 1569 Gastric cancer Fistula, prostatourethral-rectal, after brachytherapy, 2085 in Asian patients in U.S., clinical features and survival Flow cytometry in, 1183 in breast cancer, prognostic value of, 1748 biliary obstruction in, chemoradiation for, 29 in colorectal cancer, with high-frequency microsatellite circulating soluble Fas ligand in, 2560 instability, 2025 differentiated type early, gastric type mucin expression in congenital sacrococcygeal teratoma, 932 in, 724 in gastric lymphoma, 12 early stage, cathepsins in, 482 in renal cell carcinoma, p53 and bcel-2 and, 1065 hereditary prostate cancer and, 1315 Fluconazole, oral, for fungal infection prophylaxis, 1611 in Japan vs. U.S., 2237, 2555 Fluorescence bronchoscopy, in lung cancer detection, p27*'?' in, prognosis and, 1684, 2247 2468 P-glycoprotein in, p53 and, 21 2-Fluorine-18, 2-fluoro-2-deoxy-,,-glucose PET scanning, prophylactic radical lymphadenectomy with gastrec- in melanoma, 1019 tomy for, 1425 5-Fluorouracil surgery for. See Gastrectomy for breast cancer, with cyclophosphamide and metho- survival in trexate, 2521 premorbid diet and, 1205 for esophageal cancer, with radiotherapy, 946 in U.S. vs. Europe, 893 for head and neck cancer, with radiotherapy, 939 well vs. poorly differentiated, pathology and prognosis hepatic arterial infusion of, thymidylate synthase of, 1418 quantitation and in vitro chemosensitivity test- Gastric lymphoma ing for, 288 DNA content of, 12 for hepatic colorectal metastasis, 1228 soluble intercellular adhesion molecules-1 in, progno- for pancreatic cancer, via arterial infusion, 303 sis and, 1387 for renal cell carcinoma, with interleukin-2 and subcu- in Turkey, 12 taneous interferon-a, 597 Gastric metastasis, in breast cancer, presentation, endo- small intestinal toxicity of, 711 (letter) scopic features and treatment of, 2214 Folate, as cervical dysplasia marker, 376 Gastric type mucin expression, in differentiated type Follicular dendritic cell sarcoma, of neck, 664 early gastric carcinoma, 724 Foregut carcinoids, duodenal, 963 Gemcitabine Fotemustine, with interferon-a, for melanoma, 2630 for hepatocellular carcinoma, 750 Fractures, pathologic, in breast cancer, predictors of, 363 for lung cancer, 516, 543 Fragile histidine triad gene, in esophageal cancer, 5 with cisplatin, 1714 France, gallbladder cancer incidence trends and manage- with etoposide, 543 ment in, 757 Frey syndrome, botulinum toxin for, 1659 in metastatic disease, 2622 Frozen section analysis, of sentinel nodes, in melanoma, with vinorelbine, 763 1720 for pancreatic cancer, with leucovorin-modulated UFT, Functional health status 1706 in breast cancer, persistent changes in, 2176 Gene therapy symptom distress and, 1634 antiangiogenic, 1181 Fungal infections, neutropenic, oral fluconazole prophy- for prostate cancer, 1329 laxis for, 1611 Germany lung cancer histopathology in uranium workers in, 2613 G lung cancer screening in, cost-effectiveness of, 2489 Gabapentin, for interferon-alpha-2b-associated mood in- thyroid cancer in, 1 stability, 356 patterns of care for, 192 Gallbladder cancer, incidence trends and management Germ cell tumors, ovarian, conservative surgery for, 391 of, in France, 757 Gestational trophoblastic disease, cyclin E in, 673 Subject Index—Volume 89 bmxi Gleason grading, of prostate cancer, Web-based tutorial Hepatitis C for, 1818 hepatocellular carcinoma and, incidence-related fac- Glioblastoma multiforme, trofosfamide and etoposide tors in, 53 for, 2131 transforming growth factor-a mRNA in, 977 Glioma Hepatoblastoma, presenting with lung metastases, 1845 carmustine resistance in, transforming growth factor- Hepatocellular carcinoma B1-binding protein and, 850 Ca** /calmodulin-dependent protein kinase IV in, 1910 venous thromboembolism in, 640 in chronic hepatitis C, incidence-related factors in, 53 Glutathione, in pancreatic cancer, 1440 early vs. late recurrence of, risk and prognostic factors Glyceraldehyde-3-phosphate dehydrogenase, in renal for, 500 cell carcinoma, 152 gemcitabine for, 750 Grading, of prostate cancer, Web-based tutorial for, 1818 Helicobacter spp. and, 1431 Granulocyte—colony stimulating factor hepatic arterial chemoembolization for for neuroblastoma, 2122 with percutaneous microwave coagulation therapy, for nonsmall cell lung cancer, 516 1245 Group therapy, for breast cancer patients, in Japan, 1026 preoperative, 2606 Gustatory sweating, botulinum toxin for, 1659 hepatic arterial infusion chemotherapy for, thymidy- Gynecologic cancer. See also specific types late synthase quantitation and in vitro chemo- chemotherapy for, quality of life and, 1402 sensitivity testing for, 288 HFE mutations in, surgical outcome and, 297 H nuclear factor «B in, 2266 p16 inactivation in, 60 Head and neck cancer p53 in, in India, 2322 (letter) bone invasion in, interleukin-6 enhancement of, 1966 staging of, 2266 carboplatin with radiation therapy for, 2099 transforming growth factor-a mRNA in, 977 induction paclitaxel for, 2587 Hepatoma preoperative chemotherapy followed by chemoradio- hepatic arterial infusion chemotherapy for, thymidy- therapy for, 939 late synthase quantitation and in vitro chemo- radiation therapy for, mucositis in, salivary epidermal sensitivity testing for, 288 growth factor and, 2258 2-methoxyestradiol vs. docetaxel vs. paclitaxel for, 983 survival in, in India, 437 HER-2/neu, in ductal carcinoma in situ, 2153 Head and neck sarcoma, prognostic factors in, 868 Hereditary medullary thyroid carcinoma syndrome, RET Health insurance, breast cancer outcome and, 2202 mutation carriers of, thyroidectomy for, 863 Health maintenance organizations, breast cancer out- Hereditary prostate cancer, breast and gastric cancer come and, 2202 and, 1315 Healthy People 2000, breast and cervical cancer screen- Heterogeneous nuclear ribonucleoprotein A2/B1, in lung ing in Asian American and Pacific Islanders and, 696 cancer screening, 2465 HFE mutations, in hepatocellular careinoma, surgical Helicobacter spp., hepatocellular carcinoma and, 1431 Heparin, post-pneumoperitoneum survival time and, 262 outcome and, 297 Hip, osteonecrosis of, in interferon-treated chronic my- Hepatic arterial chemoembolization with percutaneous microwave coagulation therapy, eloid leukemia, 1482 HIV infection, non-Hodgkin’s lymphoma in, stem cell 1245 preoperative, in hepatocellular carcinoma, 2606 transplant for, 680 Hepatic arterial infusion chemotherapy, thymidylate syn- HMOs, breast cancer outcome and, 2202 thase quantitation and in vitro chemosensitivity Hodgkin’s disease. See also Lymphoma testing for, 288 correlation of Ga-67, SPECT, CT and lymphangiogra Hepatic failure, raltitrexed and, 890 phy in, 1371 Hepatic metastasis, in colorectal cancer epidemiology of, in Southern Taiwan, 1586 blood flow in, 1236 image-guided core-needle biopsy in, 647 distribution of, 285 survival in, in U.S. vs. Europe, 893 fibrous pseudocapsule of, 257 Homocysteine, as cervical dysplasia marker, 376 microwave coagulation therapy for, 276 Hormone receptor status pharmacokinetic modulating chemotherapy for, 1228 in breast cancer, PCR analysis of, 1732 tumor thickness and, 35 in ovarian cancer, prognosis and, 1783 vascular endothelial growth factor and, 488 Hormone replacement therapy Hepatic resection, outcome of, HFE mutations and, 297 in benign breast disease, cancer risk and, 2046 Hepatitis B, hepatocellular carcinoma and, in India, 2322 lobular breast cancer and, 1867 (letter) (letter) Hospice care, morphine in, 220 (letter) bmxii CANCER December 15, 2000 / Volume 89 / Number 12 Human immunodeficiency virus’ infection, non- Institute of Medical Informatics, patterns of care for thy- Hodgkin’s lymphoma in, stem cell transplant roid cancer in Germany, 192 for, 680 Insulin-like molecule 3, in normal vs. neoplastic breast Human pancreatic ribonuclease 1, in pancreatic cancer, tissue, 216] 1252 Insurance, breast cancer outcome and, 2202 Human papillomavirus DNA testing, vs. Pap smear, 826 Intercellular adhesion molecule-1, in non-Hodgkin’s Human papillomavirus infection, cervical cancer and, lymphoma and chronic lymphocytic leukemia, basal cell tetrasomy and p53/p21 expression during interferon therapy, 1474 and, 1300 Interferon-a Human tumor colony-forming assay, for hepatic arterial for chronic myeloid leukemia infusion chemotherapy, 288 avascular necrosis of femoral head and, 1482 Hydatidiform mole, cyclin E in, 673 in younger patients, 1647 Hypercalcemia, in breast cancer, predictors of, 363 for lymphomatoid papulosis, 1603 Hypereosinophilic syndrome, lymphomatoid papulosis for melanoma and, 2138 with cisplatin-dacarbazine-fomustine, 2630 Hypergastrinemia, duodenal carcinoids and, 963 in recurrence, 1498 Hyperthermia for metastatic osteosarcoma, with retinoic acid, 2661 for peritoneal mesothelioma, 1279 for renal cell carcinoma with radiation therapy, for prostate cancer, 399 with 5-fluorouracil and interleukin-2, 597 Hypomethylation, in acute lymphoblastic leukemia- with infusional interleukin-2 and 5-fluorouracil, 597 associated leukoencephalopathy, 925 Interferon-alpha-2b, for melanoma, mania and bipolar Hypopharyngeal cancer. See also Head and neck cancer syndromes and, 356 survival in, in India, 437 Interleukin-2, plus 5-fluorouracil and subcutaneous in- Hypoxia, in prostate tumors, stage and patient age and, terferon-a, for renal cell carcinoma, 597 2018 Interleukin-6, in oral cancer, enhanced bone invasion Hysterectomy, pelvic nerve plexus trauma during, 834, and, 1966 International Association for the Study of Lung Cancer 2144 (erratum) Worldwide Educational Program on Lung Can- cer, 2331 I International Prognostic Index, for non-Hodgkin’s lym- phoma, age classification and, 2667 ICI 182,780, for breast cancer, 817 International Union Against Cancer Ifosfamide staging system of, for nasopharyngeal cancer, 242 for nonsmall cell lung cancer, with paclitaxel and cis- Telepathology Consultation Center, 187 platin, 774 Internet-based tutorial, for prostate cancer grading, 1818 for soft tissue sarcoma, 177 Intestinal toxicity, of 5-fluorouracil, 711 (letter) Image-guided core-needle biopsy, in lymphoma, 647 Iridium-192, intraluminal, for biliary papillomatosis, 69 IMC-C225, inhibition of pancreatic tumor growth by, 74 Italy, lung cancer in, screening for, in smokers, 2345 Immune surveillance, metastatic susceptibility and, 1626 Ivory Coast, cancer incidence in, 653 Immunofluorescence, in tumor localization, using single chain Fv fragment of monoclonal antibody, 1134 J Immunoscintigraphy, carcinoembryonic antigen, for breast cancer, 104 Japan. See also Asians Immunosuppression, post-transplant, Epstein-Barr virus- gastric cancer in, vs. in U.S., 2237, 2555 associated myogenic tumors of bone and, 467 lung cancer screening in, 2392 Immunotherapy. See also specific agents and modalities computed tomography in, 2485 intratumoral injection of dendritic cells in, 2646 cost-effectiveness of, 2489 for prostate cancer, 1329 psychosocial group intervention for breast cancer pa- Incidence rates, socioeconomic status and, in Canada vs. tients in, 1026 U.S., 901 India K head and neck cancer survival in, 437 KAI1/CD82, in esophageal squamous cell carcinoma, 955 hepatocellular carcinoma in, p53 in, 2322 (letter) Kaposi sarcoma, in Ivory Coast, 653 Infertility «B, in hepatocellular carcinoma, 2266 after chemotherapy, for osteosarcoma, 1961 Ki-67 prevention of, in ovarian germ cell tumors, 391 in breast cance1 Inguinal lymphadenectomy, saphenous vein preserva- chemotherapy response and, 2145 tion in, in vulvar cancer, 1520 prognosis and, 1748 INK4A deletion, in Ewing’s sarcoma, prognosis and, 783 in Ewing’s sarcoma, prognosis and, 783

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