Calcium signalling and disease : molecular pathology of calcium

591 Pages·2007·5.426 MB·English

by  Ernesto Carafoli, Marisa Brini

Calcium Signalling
and Disease
Subcellular Biochemistry
Volume 45
SUBCELLULAR BIOCHEMISTRY
SERIES EDITOR
J.ROBINHARRIS,UniversityofMainz,Mainz,Germany
ASSISTANT EDITORS
B.B.BISWAS,UniversityofCalcutta,Calcutta,India
P.QUINN,King’sCollegeLondon,London,U.K
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Volume45 CalciumSignallingandDisease
EditedbyErnestoCarafoliandMarisaBrini
Calcium Signalling
and Disease
Molecular Pathology
of Calcium
Subcellular Biochemistry
Volume 45
Edited by
Ernesto Carafoli
UniversityofPadova,Italy
and
Marisa Brini
UniversityofPadova,Italy
ThisseriesisacontinuationofthejournalSub-CellularBiochemistry.Volume1to4ofwhichwere
publishedquarterlyfrom1972to1975
ISBN978-1-4020-6190-5(HB)
ISBN978-1-4020-6191-2(e-book)
©2007Springer
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CONTENTS
List of Contributors vii
Prologue xi
1. Annexinopathies 1
M.J. Hayes, R.E. Longbottom, M.A. Evans and S.E. Moss
2. Calpains and Human Disease 29
I. Bertipaglia and E. Carafoli
3. Gelsolin and Diseases 55
L. Spinardi and W. Witke
4. Guanylate Cyclase-Activating Proteins and Retina Disease 71
W. Baehr and K. Palczewski
5. Pathologies Involving the S100 Proteins and Rage 93
C.W. Heizmann, G.E. Ackermann and A. Galichet
6. The Calcium-Sensing Receptor: Physiology, Pathophysiology
and CaR-Based Therapeutics 139
E.M. Brown
7. Physiological Roles of the Ca2+/CaM-Dependent Protein Kinase
Cascade in Health and Disease 169
J. Colomer and A.R. Means
8. Calcium Channelopathies: Voltage-gated Calcium Channels 215
P.J. Adams and T.P. Snutch
9. TRP Channels in Disease 253
S.E. Jordt and B.E. Ehrlich
10. Diseases Associated with Altered Ryanodine Receptor Activity 273
W.J. Durham, X.H.T. Wehrens, S. Sood and S.L. Hamilton
v
vi Contents
11. Inositol 1,4,5-tripshosphate Receptor, Calcium Signalling
and Huntington’s Disease 323
I. Bezprozvanny
12. SERCA Pumps and Human Diseases 337
A. Hovnanian
13. The Plasma Membrane Calcium ATPase and Disease 365
B.L Tempel and D.J. Shilling
14. Diseases Involving the Golgi Calcium Pump 385
J.Vanoevelen,L.Dode,L.Raeymaekers,F.WuytackandL.Missiaen
15. Calcium Signalling and Cancer Cell Growth 405
T. Capiod, Y. Shuba, R. Skryma and N. Prevarskaya
16. Calcium Misregulation and the Pathogenesis of Muscular Dystrophy 429
F.W. Hopf, P.R. Turner and R.A. Steinhardt
17. Calcium and Cell Death 465
A. Verkhratsky
18. Calcium and Cell Death: The Mitochondrial Connection 481
P. Bernardi and A. Rasola
19. Role of Calcium in the Pathogenesis of Alzheimer’s Disease
and Transgenic Models 507
K.N. Green, I.F. Smith and F.M. LaFerla
20. Calcium and Cardiomyopathies 523
E.G. Kranias and D.M. Bers
21. Calcium Signalling and Calcium Transport in Bone Disease 539
H.C. Blair, P.H. Schlesinger, C.L.-H. Huang and M. Zaidi
Index 563
Colour Plates 567
LIST OF CONTRIBUTORS
M.J. Hayes, R.E. Longbottom, M.A. Evans and S.E. Moss
Div.ofCellBiology,UniversityCollegeLondonInstituteofOphthalmology,11–43
Bath Street, London EC1V 9EL, UK
I. Bertipaglia and E. Carafoli
Department of Biochemistry, University of Padova, and Venetian Institute of
Molecular Medicine, Padova, Italy
L. Spinardi
Direzione Scientifica, IRCCS Fondazione Ospedale Policlinico, Mangiagalli
e Regina Elena, Via Francesco Sforza 28, 20122 Milano, Italy
W. Witke
EMBL Monterotondo, Via Ramarini 32, 00096 Monterotondo, Rome, Italy
W. Baehr
Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake
City, Utah 84112-5339, USA
K. Palczewski
Department of Pharmacology, Case School of Medicine, Case Western Reserve
University, Cleveland, Ohio 44106-4965, USA
C.W. Heizmann, G.E. Ackermann and A. Galichet
Division of Clinical Chemistry and Biochemistry, Department of Pediatrics,
University of Zurich, Switzerland
E.M. Brown
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine,
Brigham and Women’s Hospital and Harvard Medical School, 221 Longwood
Avenue, 02115 Boston, MA, USA
J. Colomer and A.R. Means
DepartmentofPharmacologyandCancerBiology,DukeUniversityMedicalCenter
P.J. Adams
MichaelSmithLaboratorie,UniversityofBritishColumbia,Vancouver,BC,Canada
V6T1Z4
vii
viii List of contributors
T.P. Snutch
Neuromed Pharmaceuticals Inc., 2389 Health Sciences Mall Vancouver, BC,
Canada V6T1Z4
S.E. Jordt and B.E. Ehrlich
Department of Pharmacology, Yale University School of Medicine, Department of
Pharmacology, 333 Cedar Street, New Haven, CT 06520-8066
W.J. Durham, S. Sood and S.L. Hamilton
Department of Molecular Physiology and Biophysics
X.H.T. Wehrens
Department of Molecular Physiology and Biophysics, Department of Medicine
(Division of Cardiology), Baylor College of Medicine, Houston, TX 77030
I. Bezprozvanny
Department of Physiology, University of Texas Southwestern Medical Center at
Dallas, Dallas, Texas 75390, USA
A. Hovnanian
INSERM,U563,Toulouse,F-31300France;UniversitéToulouseIIIPaul-Sabatier,
UMR-S 563, Toulouse, F-31400 France
B.L Tempel and D.J. Shilling
The Department of Otolaryngology-Head and Neck Surgery, the Department of
Pharmacology, and the V.M. Bloedel Hearing Research Center; University of
Washington School of Medicine, Seattle WA 98195-7923, USA
J. Vanoevelen, L. Dode, L. Raeymaekers, F. Wuytack and L. Missiaen
Laboratory of Physiology, KULeuven Campus Gasthuisberg O&N1, Herestraat 49
bus 802, B-3000 Leuven, Belgium
T. Capiod, R. Skryma and N. Prevarskaya
INSERM U800, Laboratoire de Physiologie Cellulaire, Université des Sciences et
Technologies Lille 1, 59655 Villeneuve d’Ascq Cedex, France
Y. Shuba
Bogomoletz Institute of Physiology, NASU, Bogomoletz Str, 4, 01024 Kiev-24,
Ukraine
F.W. Hopf
Ernest Gallo Clinic and Research Center, University of California, San Francisco,
5858 Horton St., Suite 200, Emeryville, CA 94608
P.R. Turner
Panomics, 6519 Dumbarton Circle, Fremont, CA, 94555
R.A. Steinhardt
Department of Molecular and Cell biology, University of California, Berkeley,
Berkeley, CA 94720-3200
List of contributors ix
A. Verkhratsky
Faculty of Life Sciences, The University of Manchester, 1.124 Stopford Building,
Oxford Road,Manchester M13 9PT, UK
P. Bernardi and A. Rasola
Department of Biomedical Sciences, University of Padova, Viale Giuseppe
Colombo 3, 35121 Padova, Italy
K.N. Green, I.F. Smith and F.M. LaFerla
Department of Neurobiology and Behavior, University of California, Irvine CA
92697-4545
E.G. Kranias
DepartmentofPharmacologyandCellBiophysics,CollegeofMedicine,University
of Cincinnati, Cincinnati, OH 45267
D.M. Bers
DepartmentofPhysiology,LoyolaUniversityChicago,StritchSchoolofMedicine,
Maywood, IL 60153
H.C. Blair, P.H. Schlesinger, Christopher L.-H. Huang and M. Zaidi
Departments of Pathology and of Cell Biology and Physiology, University of
PittsburghandVeterans’AffairsHealthSystem,Pittsburgh,PA15261,Department
of Physiology and Cell Biology, Washington University School of Medicine, St.
Louis,MO63110,PhysiologicalLaboratory,UniversityofCambridge,Cambridge,
CB2 3EG, United Kingdom, and The Bone Program, Mount Sinai School of
Medicine, New York, New York 10029