BRITISH MEDICAL BULLETIN Volume 58 2001 The changing face of HIV and AIDS Scientific Editors: Robin A Weiss, Michael W Adler and Sarah L Rowland-Jones Preface Robin A Weiss, Michael W Adler and Sarab L Rowland-]ones Introduction Peter Piot The global epidemiology of HIV/AIDS Linda Morison Evolutionary and immunological implications of contemporary HIV-1 variation Bette Korber, Brian Gaschen, Karina Yusim, Rama Thakallapally, Can Kesmir and Vincent Detours HIV-1 receptors and cell tropism Paul R Clapham and Aine McKnight The Ip athogenesis of HIV-1 infection Jonathan Weber Demography and economics of HIV/AIDS Alan Whiteside Paediatric HIV infection: correlates of protective immunity and global perspectives in prevention and management Philip ]R Goulder, Prakash Jeena, Gareth Tudor-Williams and Sandra Burchett HIV-1 transmission and acute HIV-1 infection Pokrath Hansasuta and Sarah L Rowland-Jones Interventions against sexually transmitted infections (STI) to prevent HIV infection Philippe Mayaud and Duncan McCormick Behavioural interventions to prevent HIV infection: rapid evolution, increasing rigour, moderate success C Bonell and J Imrie HIV care in non-industrialised countries Charles F Gilks Immune interventions John Wilkinson and Frances Gotch Prospect of a prophylactic vaccine for HIV T Hanke Index http://www.bmb.oupjournals.org