Table Of Content

VOLUME 77 - CONTENTS No | JANUARY 1993 Page Editorial l Diabetes, glaucoma, sex, and cataract D W Flanagan Original articles — Clinical science Diabetes, glaucoma, sex, and cataract: analysis of combined data from two case control studies John JH arding, Muriel Egerton, Ruth van Heyningen, Ruth S Harding Loss of contrast sensitivity in diabetic patients with LOCS II classified cataracts Leo T Chylack Jr, Nita Padhye, Patricia M Khu, Caroline Wehner, John Wolfe, Daniel McCarthy, Bernard Rosner, Judith Friend Relationship of regression pattern to recurrence in retinoblastoma A D Singh, D Garway-Heath, S Love, P N Plowman, JF E Kingston, 7 L Hungerford Prevalence of glaucoma in the west of Ireland Michele Coffey, Angela Reidy, Richard Wormald, Wu Xing Xian, Lesley Wright, Parul Courtney Reproducibility of transcranial Doppler ultrasound examinations of the ophthalmic artery flow velocity Prin Rojanapongpun, Brenda Morrison, Stephen M Drance Ophthalmic artery flow velocity in glaucomatous and normal subjects Prin Rojanapongpun, Stephen M Drance, Brenda 7 Morrison Visual loss in an onchocerciasis endemic community in Sierra Leone 7 A G Whitworth, C E Gilbert, D M Mabey, D Morgan, A Foster Choroidal rupture and optic atrophy Lou C Glazer, Dennis P Han, Mark S Gottlieb Cataract development and outcome of surgery in bone marrow transplanted children B M Calissendorff, P Bolme Laboratory science Increased D-arabinitol/creatinine ratio in sera of patients with Behcet’s disease during an active phase Seiji Hayasaka, Sachiko Noda, Tomoichi Setogawa Microbial contamination of contact lens cases in the west of Scotland P Devonshire, F A Munro, C Abernethy, B 7 Clark Pinealitis accompanying equine recurrent uveitis Carolyn M Kalsow, Ann E Dwyer, Andrew W Smith, Thomas P Nifong Perspective Disease and risks associated with contact lenses John K G Dart Case reports Monostotic fibrous dysplasia of the orbit: an unusual lacrimal fossa mass Peter McCluskey, Richard Wingate, Ross Benger, Stanley McCarthy Early treatment of juvenile xanthogranuloma of the iris with subconjunctival steroids J Casteels, 7O lver, M Malone, D Taylor Sporothrix schenckii endophthalmitis presenting as granulomatous uveitis Mont 7C artwright, Mark Promersberger, Garth A Stevens Letters to the editor Notices Instructions for authors No 2 FEBRUARY 1993 Editorials The Farnsworth-Munsell 100 hue test and optic neuritis Creig S Hoyt Trachoma — the future for a disease of the past Hugh R Taylor Original articles — Clinical science The Farnsworth-Munsell 100 hue test in the first episode of demyelinating optic neuritis MF Ménage, D Papakostopoulos, 7 C Dean Hart, S Papakostopoulos, Yu Gogolitsyn Clinical and infrared pupillometry in central retinal vein occlusion P A Bloom, D Papakostopoulos, Y Gogolitsyn, J A Leenderz, S Papakostopoulos, R H B Grey Results of community-based eyelid surgery for trichiasis due to trachoma Heidrun Bog, David Yorston, Allen Foster Retinitis pigmentosa, ataxia, and mental retardation associated with mitochondrial DNA mutation in an Italian family Piero Puddu, Piero Barboni, Vilma Mantovani, Pasquale Montagna, Angelina Cerullo, Michela Bragliani, Carla Molinotti, Roberto Caramazza Influence of a thalassaemia on the retinopathy of homozygous sickle cell disease Peter D Fox, Douglas R Higgs, Graham R Serjeant Follow-up study on premature infants with and without retinopathy of prematurity Rosemary Robinson, Michael O’ Keefe Choroidoretinal neovascularisation following radon seed treatment of retinoblastoma in two patients D B Archer, W M K Amoaku, G Kelly Orbital volume measurement in the management of pure blowout fractures of the orbital floor D G Charteris, C-H Chan, R W Whitehouse, 7 L Noble Laboratory science Direct clinico-histological correlation of parapapillary chorioretinal atrophy Toshiaki Kubota, Fost B Fonas, Gottfried O H Naumann Detection of Toxoplasma gondii in aqueous humour by the polymerase chain reaction F Aouizerate, }C azenave, L Poirier, Ph Verin, A Cheyrou, 7B egueret, F Lagoutte The EP, receptor is the predominant prostanoid receptor in the human ciliary muscle Toshihiko Matsuo, Max S Cynader Perspective The x’ test for data collected on eyes John R Thompson Case reports Churg-Strauss vasculitis presenting with severe visual loss due to bilateral sequential optic neuropathyJ F Acheson, OC Cockerell, C R Bentley, M D Sanders Secondary retinitis pigmentosa and cerebral demyelination in Lyme borreliosis Anni Karma, Tuula A Pirtuld, Matti K Viljanen, Yrj6 E Lahde, Christina M Raitta Two cases of coloboma associated with unbalanced translocations Michael Goggin, Michael O’Keefe, Helen Hughes Spontaneous development of retinal ischaemia and rubeosis in eyes with retinal racemose angioma Philip A Bloom, Alistair Laidlaw, David L Easty Ocular involvement in mycosis fungoides R Fane Leitch, lan G Rennie, M Andrew Parsons Letters to the editor Bookreviews Notices Instructions for authors Contents No 3 MARCH 1993 Editorials Intraocular metastasis Alison McCartney Molecular genetics as a ‘probe’ in ophthalmology Neva Haites Original articles — Clinical science Prophylactic use of acetazolamide to prevent intraocular pressure elevation following Nd-Y AG laser posterior capsulotomy Joannis D Ladas, George P Pavlopoulos, Stefanos N Kokolakis, George P Theodossiadis Internal sclerostomy using laser ablation of dyed sclera in glaucoma patients: a pilot study Shlomo Melamed, Arieh Solomon, Doron Neumann, Ami Hirsh, Michael Blumenthal, Michael Belkin Transient hyperopia with lens swelling at initial therapy in diabetes Y Saito, G Ohmi, S Kinoshita, Y Nakamura, K Ogawa, S Harino, M Okada Analysis of the incidence of intraocular metastasis Leonard Weiss Continuous curvilinear (circular) capsulorhexis and planned extracapsular cataract extraction — are they compatible? Milind Pande Permeability of the blood-ocular barrier in adolescent and adult diabetic patients Akitoshi Yoshida, Satoshi Ishiko, Miutsuru Kopima, Hironobu Ogasawara Ophthalmic findings in classical galactosaemia — prospective study Bijan Beigi, Michael O’Keefe, Roger Bowell, E:leen Naughten, Nadia Badawi, Bernadette Lamgan Laboratory science Conjunctival biopsy in adult form galactosialidosis Tomoaki Usui, Shoichi Sawaguchi, Haruki Abe, Kazuo Iwata, Kryomutsu Oyanagt X linked exudative vitreoretinopathy: clinical features and genetic linkage analysis P Fullwood, 7F ones, S Bundey, J Dudgeon, A R Fielder, M W Kilpatrick Nasal administration of retinal antigens suppresses the inflammatory response in experimental allergic uveoretinitis: a preliminary report of intranasal induction of tolerance with retinal antigens A D Dick, Y F Cheng, A McKinnon, FJ Liversidge, 7 V Forrester Perspective The rate of visual field loss in untreated primary open angle glaucoma Jeffrey L Fay, John R Murdoch Case reports Proptosis as a presenting sign of extradural haematoma C R Stewart, J F Salmon, Z Domingo, A D N Murray Iris crystals in chronic iridocyclitis Sheridan Lam, Howard H Tessler, Karen Winchester, Holly van Hecke, Byron L Lam Coxsackievirus B3-associated panuveitis Werner Forster, Alexander A Bialasiewicz, Holger Busse Anterior visual system involvement in non-Hodgkin’s lymphoma A G Zaman, E M Graham, M D Sanders Necrotic orbital melanoma arising de novo Ferry A Shields, Carol L Shields, Ralph C Eagle Fr, Patrick De Potter, Glen L Oliver Late onset esotropia in monozygous twins S Ahmed, 7 D H Young Presumed corneal intraepithelial neoplasia associated with contact lens wear and intense ultraviolet light exposure Yan Guex-Crosier, Carl P Herbort Intracranial hypertension and papilloedema in chronic inflammatory demyelinating polyneuropathy Aldo Fantn, Richard M Feist, Chittaranjan V Reddy Letters to the editor Bookreview Notices Instructions for authors No 4 APRIL 1993 Editorials Expanding the role of vitrectomy in retinal reattachment surgery Peter Leaver Ocular complications of diabetes after cataract extraction Tom Barrie Original articles — Clinical science Pars plana vitrectomy for the treatment of rhegmatogenous retinal detachment uncomplicated by advanced proliferative vitreoretinopathy D S Gartry, A H Chignell, W A Franks, D Wong Removal of silicone oil following diabetic vitrectomy R V Pearson, D McLeod, Z F Gregor Cystoid macular oedema after extracapsular cataract extraction and intraocular lens implantation in diabetic patients without retinopathy Ugo Menchini, Francesco Bandello, Rosario Brancato, Fabrizio I Camesasca, Marcello Galdini Retinal detachment following anterior chamber lens implantation for the correction of ultra-high myopia in phakic eyes AJ E Foss, P H Rosen, R F Cooling Is the season of birth a risk factor in glaucoma? Robert Weale Photocoagulation of choroidal neovascular membranes with a diode laser Michael W Ulbig, Dominic A McHugh, A M Peter Hamilton Clinical features of affected males with X linked ocular albinism S 7 Charles, 7 S Green, 7 W Grant, 7 R W Yates, AT Moore Ocular and vision defects in preschool children Maureen Stayte, Barnaby Reeves, Catherine Wortham Laboratory science Occlusion of retinal vessels using targeted delivery of a platelet aggregating agent Yuichiro Ogura, Theresa Guran, Kanyi Takahashi, Ran Zeimer Origin of fibronectin in epiretinal membranes of proliferative vitreoretinopathy and proliferative diabetic retinopathy Salvatore Grisanti, Klaus Heimann, Peter Wiedemann Perspective Photorefractive keratectomy: implications of corneal wound healing StephenJ Tuft, David S Gartry, lan M Rawe, Keith M Meek Case reports Primary lipid keratopathy: a morphological and biochemical assessment Anténio Silva-Aratijo, Maria Amélia Tavares, Maria Manuela Lemos, Maria Isabel Soares, José Castro-Correia, José Salgado-Borges Serious corneal complications of 5-fluorouracil Marie Hickey-Dwyer, P K Wishart Bilateral streptococcal corneoscleritis complicating f irradiation induced scleral necrosis Anthony P Moriarty, Geoffrey JC rawford, lan L McAllister, lan 7C onstable Ocular toxocariasis in a patient with repeatedly negative ELISA titre to Toxocara canis James A Sharkey, Peter S McKay The trap of the displaced blind spot in automated perimetry Avinoam B Safran, Gordana Sunaric, Albert Burger IgG-x extramedullary plasmacytoma of the conjunctiva and orbit Kazuaki Tetsumoto, Hiroshi Iwaki, Masanori Inoue Letter to the editor Bookreviews Notices Instructions for authors No 5 MAY 1993 Editorials Treatment of age-related subfoveal neovascular membranes by teletherapy J H Chisholm New entities in uveitis Susan Lightman Measurement of flare D 7 Spalton Original articles — Clinical science Treatment of age-related subfoveal neovascular membranes by teletherapy: a pilot study Usha Chakravarthy, Russell F Houston, Desmond B Archer Clinical features of HTLV-I associated uveitis Kumiko Nakao, Norio Ohba Aqueous flare and cells in eyes with retinal vein occlusion — correlation with retinal fluorescein angiographic findings N X Nguyen, M Kiichle Manchineel keratoconjunctivitJiosh n F Pitts, Nigel H Barker, D Clive Gibbons, Jeffrey L Jay Distichiasis: management with cryotherapy to the posterior lamella B A O’ Donnell, 7 Richard O Collin ‘Correctable undetected visual acuity deficit’ in patients aged 65 and over attending an accident and emergency department D Z Reinstein, N L Dorward, R P L Wormald, A Graham, I O’Connor, R M Charlton, M Yeatman, R Dodenhoff, R Touquet, T Challoner Laboratory science Quantification of melanin and iron content in uveal malignant melanomas and correlation with magnetic resonance imageJ D Ferris, P A Bloom, P R Goddard, C Collins Primary open angle glaucomas in the rhesus monkey William W Dawson, Dennis E Brooks, George M Hope, Donald A Samuelson, Mark B Sherwood, Harry M Engel, Matthew7 Kessler Finger prick blood testing in Leber hereditary optic neuropathy David Mackey, Steve Nasioulas, Susan Forrest Perspective Orbital meningiomas: surgery, radiotherapy, or hormones? Geoffrey E Rose Case reports Impairment of tritan colour vision after initiation of treatment with zidovudine in patients with HIV disease or AIDS Stephan A Geier, Manfred Held, Johannes R Bogner, Ursula Kronawitter, Thomas Berninger, Volker Klauss, Frank D Goebel Bilateral retinal haemorrhages following epidural injection C Ling, P L Atkinson, CG F Munton Panuveitis and multifocal retinitis in a patient with leucocytoclastic vasculitis James C Tsai, David7 Forster, Richard R Ober, Narsing A Rao Successful treatment of anisometropic amblyopia and strabismus following intravitreal silicone oil R R Goble, W A Franks, D Avery, A H Chignell Notices Instructions for authors No 6 JUNE 1993 Editorials An alternative approach to corneoscleral repair D 7 Coster Glaucoma screening R A Hitchings Original articles — Clinical science Use of split-thickness dermal grafts to repair corneal and scleral defects — a study of 10 patients Foseph A Mauriello Fr, Kathryn Pokorny Clinical evaluation of am ulti-fixation campimeter for the detection of glaucomatous visual field loss Erkan Mutlukan, Bertil E Damatwo, Jeffrey L Fay Investigation of limbal touch sensitivity using a Cochet-Bonnet aesthesiometer 7 G Lawrenson, G L Ruskell Effect of topical ketanserin administration on intraocular pressure C Costagliola, G Iuliano, M Rinaldi, V Russo, G Scibelli, L Mastropasqua Subretinal exudative deposits in central serous chorioretinopathy Darmakusuma Ie, Lawrence A Yannuzzi, Richard F Spaide, Maurice F Rabb, Norman P Blair, Mark F Daily Lens opacities in neurofibromatosis 2: further significant correlations Evrydiki A Bouzas, Valeria Freidlin, Dilys M Parry, Roswell Eldridge, Muriel IK aiser-Kupfer Congenital rubella syndrome: ophthalmic manifestations and associated systemic disorders Kerry T Givens, David A Lee, Thomas Jones, Duane M I| strup Reduction in mydriatic drop size in premature infants S Wheatcroft, A Sharma, ¥ McAllister Laboratory science Pathogenesis of acanthamoebic keratitis: hypothesis based on a histological analysis of 30 cases Alec Garner Perspective Ocular involvement in toxoplasmosis Aniki Rothova Case reports Dominantly inherited unilateral retinal dysplasia / C Lloyd, A Colley, A B Tullo, R Bonshek Anomalous Cloquet’s canal in a case of optic nervehead coloboma associated with extensive retinal detachment Jun Akiba, Akitoshi Yoshida, Isao Ohta, Hiromasa Igarashi, Akihiro Kakehashi Neurocytoma of the retina Cecily Metcalf, Edward M Mele, Ian McAllister Optic nerve pit with serous macular detachment resulting in rhegmatogenous retinal detachment G P Theodossiadis, Ch Koutsandrea, P G Theodossiadis Aspergillus terreus postoperative endophthalmitis Taraprasad Das, Prateep Vyas, Savitri Sharma Scytalidium dimidiatum fungal endophthalmitis Ali A Al-Rajhi, Abdulaziz H Awad, Saleh S A Al-Hedaithy, Richard K Forster, Kay C Caldwell Displaced intraocular lens repositioning using a reversed 10-0 straight polypropylene needle lasso technique J D Stevens, A M P Hamilton History of ophthalmology Referees Letters to the editor Bookreview Notices Instructions for authors No 7 JULY 1993 Editorials The evolving role of visual electrodiagnostiJcosh n R Heckenlively Blindness in the developing world Allen Foster, Gordon Johnson Contents Original articles — Clinical science Age-related Bruch’s membrane change: a clinical study of the relative role of heredity and environment Bertrand Piguet, Fohn A Wells, Inge B Palmvang, Richard Wormald, lain H Chisholm, Alan C Bird Cone dystrophies with negative photopic electroretinogram Ulrich Kellner, Michael H Foerster Blindness in Africa: Zimbabwe schools for the blind survey Larry Schwab, Kenneth Kagame Congenital glaucoma in the West Bank and Gaza Strip Mark 7 Elder A population based, prospective study of the development of ROP in prematurely born children in the Stockholm area of Sweden G Holmstrim, M el Azazi, L Facobson, G Lennerstrand Monocular temporal hemianopia Seymour A Hershenfeld, James A Sharpe Suture needle drainage of subretinal fluid G L Raymond, M J Lavin, C L Dodd, D McLeod Decreased choroidal thickness in eyes with secondary angle closure glaucoma Toshiaki Kubota, Fost B Jonas, Gottfried O H Naumann Role of mitomycin C in pterygium surgery P S Mahar, G E Nwokora Laboratory science Does autoimmunity to S-antigen play a role in Fuchs’ heterochromic cyclitis? E La Hey, L Broersma, R van der Gaag, G S Baarsma, A Rothova, A Kylstra Antigen presentation of herpes simplex virus by corneal epithelium — an in vitre and in vivo study G T Fahy, D C Hooper, DL Easty Perspective Primary surgery for primary open angle glaucoma — justified or not? R A Hutchings Case reports Adult nasolacrimal duct bypass tubes: where do they go? Hubertus v Below, Geoffrey E Rose Simultaneous retinal and optic nerve lesions in toxoplasmosis: the advantages of magnetic resonance imaging F-X Borruat, R Kapoor, M D Sanders Focal electroretinogram and visual field defect in multiple evanescent white dot syndrome Masayuki Horiguchi, Yozo Miyake, Makoto Nakamura, Yukari Fujti Contralateral active ocular toxoplasmosis in Fuchs’ heterochromic cyclitis E La Hey, G S Baarsma Resolution of an external layer macular hole associated with an optic nerve pit after laser photocoagulation Philip M Falcone, Peter L Lou A case of presumed congenital herpes zoster ophthalmicus 7 Singh, 7M Gibson Orbital multiple myeloma mimucking acquired angio-oedema Rebecca L Snider, Bruce H Thiers, Gene R Howard History of ophthalmology Letters to the editor Obituary Notices Instructions for authors No 8 AUGUST 1993 Editorials Hereditary retinopathies: insights into a complex genetic aetiology Peter Humphries Psychophysical testing in glaucoma Roger Hutchings Original articles — Clinical science Autosomal dominant retinitis pigmentosa with apparent incomplete penetrance: a clinical, electrophysiological , psychophysical, and molecular genetic study A T Moore, F Fitzke, M Jay, G B Arden, C F Inglehearn, T 7 Keen, S S Bhattacharya, A C Bird Uveitis and Lyme borreliosis 7 Breeveld, H Kuiper, L Spanjaard, L Luyendijk, A Rothova Quantification of lacrimal function after D-shaped field irradiation for retinoblastoma S M Imhof, P Hofman, KEWPTan Treatment of vitreous floaters with neodymium YAG laser Wu-Fu Tsai, Yen-Chih Chen, Chorng-Yi Su Glare sensitivity in early cataracts Maria Susan M Lasa, Marvin J Podgor, Manuel B Datiles III, Rafael C Caruso, Benjamin V Magno Monocular visual outcome in untreated early onset esotropia William V Good, Luis C F da Sa, Christopher J Lyons, Creig S Hoyt Laboratory science Ocular findings in a family with autosomal dominant retinitis pigmentosa and a frameshift mutation altering the carboxy! terminal sequence of rhodopsin Eckart Apfelstedt-Sylia, Markus Kunisch, Monika Horn, Klaus Riither, Heinrich Gerding, Andreas Gal, E berhart Zrenner Chronic ocular hypertension alters local retinal responsiveness Ron Ofri, William W Dawson, Kimberly Folt, Kirk N Gelatt Activated T cells in an animal model of allergic conjunctivitis J Carreras, B Carreras, Lindsay McGrath, Ann Rice, DLE Easty Perspective Collagens in ocular tissues G E Marshall, AG P Konstas, W R Lee Case reports Penetrating keratoplasty in severe ocular graft versus host disease 7D Heath, 7 F Acheson, W E Schulenburg Orbital plexiform neurofibroma Veronica M G Ferguson, Peter M Kyle Thelaziasis: a report of two cases T Shantikumar Singh, K Nareshkumar Singh Sedation with nasal ketamine and midazolam for cryotherapy in retinopathy of prematurity André Louon, Joan Lithander, Venu Gopal Reddy, Anil Gupta Congenital third nerve palsy associated with mid-trimester amniocentesis C K Patel, D S I Taylor, I M Russell-E ggitt, A Kriss, P Demaerel Evaluation of idiopathic epiretinal membranes by a scanning laser ophthalmoscope Yuichiro Ogura, Yoshihito Honda History of ophthalmology Letters to the editor Bookreviews Notices Instructions for authors No 9 SEPTEMBER 1993 Editorials Factors influencing metastasis in retinoblastoJmoah n Hungerford Anaesthesia for ophthalmic surgery E manuel Rosen Original articles — Clinical science Choroidal invasion of retinoblastoma: metastatic potential and clinical risk factors Carol L Shields, Ferry A Shields, Karin A Baez, Jacqueline Cater, Patrick V De Potter Contents Symptomatic abnormalities of dark adaptation in patients with age-related Bruch’s membrane change Robert L Steinmetz, Robert Haimovici, Chris Jubb, Frederick W Fitzke, Alan C Bird Stage III macular hole surgery Juan Orellana, Ronni M Lieberman Diode laser for retinopathy of prematurity — early outcome Michael Goggin, Michael O’ Keefe Dissociated eye movements in craniosynostosis: a hypothesis revived H Cheng, M A Burdon, G A Shun-Shin, S Czypionka Limbal and corneal calcification in patients with chronic renal failure N Klaassen-Broekema, O P van Bijsterveld Prevention of intraocular pressure rise following intravitreal injection Nigel Morlet, Stephanie H Young Laboratory science Ultrastructure of retinal vessels in diabetic patients Tatsuro Ishibashi, Hajime Inomata Cataract and myotonic dystrophy: the role of molecular diagnosis W Reardon, 7 C MacMillan, 7 Myring, H G Harley, S A Rundle, L Beck, P S Harper, D7 Shaw Cellular autoimmunity to retinal specific antigens in patients with Behcet’s disease 7 H Yamamoto, M Minami, G Inaba, K Masuda, M Mochizuki Perspective Adverse effects of topical antiglaucomatous medications on the conjunctiva David Broadway, Ian Grierson, Roger Hitchings Case reports Ocular melanomas in xeroderma pigmentosum A 7 Vivian, D W Ellison, 7 I McGill Intracavernous chondrosarcoma associated with Ollier’s disease D 7 Brazier, 7 Roberts-Harry, A Crockard A rare cause of visual loss in AIDS patients: central retinal vein occlusion Yahya Ismail, Patrick M Nemechek, Edward L Arsura Persistent visual changes following hashish consumption Gian Luca Laffi, Avinoam B Safran Dirofilariasis: an uncommon parasitosis of the eye Merih Soylu, Kadri Ozcan, Miislime Yalaz, Seyhan Varinli, Giilhan Slem Retrobulbar oedema after ophthalmic plaque radiotherapy Paul T Finger, Sandra Frazier Byrne, Darius M Moshfeghi, Henry D Perry Retinal arterial macroaneurysm in a patient with congenital heart disease Ahmed M Abu El-Asrar, Abdulaziz Awad, Khalid F Tabbara Visual loss from central serous retinopathy in systemic lupus erythematosus M B Eckstein, D 7 Spalton, G Holder History of ophthalmology Letters to the editor Notices Instructions for authors No 10 OCTOBER 1993 Editorials Local resection of choroidal melanoma Jan Rennie Choroidal neovascularisation in age-related macular disease Alan C Bird Original articles — Clinical science Predictive factors of visual outcome after local resection of choroidal melanoma Bertil E Damato, James Paul, Wallace S Foulds Clinical predictive factors for development of recurrence and metastasis in conjunctival melanoma: a review of 68 cases Patrick De Potter, Carol L Shields, Ferry A Shields, Hyman Menduke Post-traumatic angle recession glaucoma: a risk factor for bleb failure after trabeculectomy André Mermoud, John F Salmon, Clive Straker, Anthony D N Murray Spontaneous hyphaema associated with anterior uveitis Donald S Fong, Michael B Raizman The fixed dilated pupil after cataract surgery — is it related to intraocular use of hypromellose? Andrew K K Tan, Roger C Humphry Ophthalmic features and visual prognosis in the Treacher-Collins syndrome Richard W Hertle, Sule Ziylan, James A Katowitz Ocular fundus in neurofibromatosis type 2 Klara Landau, Gazi M Yasargil Corneal transplantation in the United Kingdom and Republic of Ireland A Vail, S M Gore, B A Bradley, D L Easty, C A Rogers on behalf of collaborating surgeons Laboratory science Early stages of age-related macular degeneration: an immunofluorescence and electron microscopy study Theo L van der Schaft, Cornelia M Mooy, Wim C de Bruijn, Paul T V M de Fong Perspective Clinical and genetic patterns of neurofibromatosis | and 2 Nicola K Ragge Case reports Bilateral optic neuropathy and white dot syndrome following a mycoplasmal infection M Cordonnier, L E Caspers-Velu, C Facquemin, C Van Nechel, M Tombroff Orbital masquerade: hyperthyroidism and cavernous haemangioma of the orbit Martin L Leib Slow accommodation release with a cerebellar lesion Tsutomu Kawasaki, Motohiro Kiyosawa, Tadashi Fujino, Takashi Tokoro Neurotrophic keratitis presenting in infancy with involvement of the motor component of the trigeminal nerve 7 D Heath, G Long History of ophthalmology Letters to the editor Bookreview Notices Correction Instructions for authors No 11 NOVEMBER 1993 Editorials Melanomas, metastases, and survival Jan Rennie Macrophages in the pathobiology of epiretinal membranes: multifunctional cells for a multistage process Paul Hiscott Original articles — Clinical science Prognostic factors following enucleation of 111 uveal melanomas Kate Coleman, Jan P A Baak, Paul Van Diest, Joan Mullaney, Michael Farrell, Maurice Fenton Effects of topical mitomycin C on primary trabeculectomies and combined procedures Vital P Costa, Marlene R Moster, Richard P Wilson, Courtland M Schmidt, Sai Gandham, Maura Smith Pterygium excision with conjunctival autografting: an effective and safe technique Bruce D S Allan, Perry Short, Geoffrey } Crawford, Graham D Barrett, Ian ¥C onstable Contents Treatment of band keratopathy by excimer laser phototherapeutic keratectomy: surgical techniques and long term follow up D P S O’Brart, D S Gartry, C P Lohmann, A L Patmore, M G Kerr Muir, J Marshall Contrast sensitivity function in Graves’ ophthalmopathy and dysthyroid optic neuropathy Maria S A Suttorp-Schulten, Rob Tyssen, Maarten Ph Mourits, Patricia Apkarian A comparison of the efficacy and duration of action of topically applied proxymetacaine using a novel ophthalmic delivery system versus eye drops in healthy young volunteers 7G Lawrenson, D F Edgar, AC Gudgeon, J M Burns, M Geraint, N A S Barnard Impairment of colour contrast sensitivity and neuroretinal dysfunction in patients with symptomatic HIV infection or AIDS Stephan A Geier, Ursula Kronawitter, Johannes R Bogner, Gertrud Hammel, Thomas Berninger, Volker Klauss, Frank D Goebel The effect of pilocarpine on the glaucomatous visual field Andrew R Webster, Andrew J Luff, Christopher R Canning, Andrew R Elkington Visual field loss with capillary non-perfusion in preproliferative and early proliferative diabetic retinopathy Caroline K L Chee, Declan W Flanagan Laboratory science Macrophages in proliferative vitreoretinopathy and proliferative diabetic retinopathy: differentiation of subpopulations Peter Esser, Klaus Heimann. Peter Wiedemann Perspective Pterygium as an early indicator of ultraviolet insolation: a hypothesis M T Coroneo Case reports Contact allergic dermatitis and contact urticaria due to topical ophthalmic preparations B F O’Donnell, I S Foulds Iris cyst after traumatic implantation of an eyelash into the anterior chamber H B Hoh, M 7 Menage, C Dean-Hart Recurrent episcleritis associated with adult T cell leukaemia Kaori Goto, Miyuki Sugita, Kazushiro Okada, Hiroshi Hatano, Nobuhisa Ishiguro, Takashi Y oshiki, Shigeaki Ohno Development of retinal vascular leakage and cystoid macular oedema secondary to central serous chorioretinopathy Howard Schatz, Mark D Osterloh, H Richard McDonald, Robert N Johnson Familial clustering of human T lymphotropic virus type | uveitis Shinji Araki, Manabu Mochizuki, Kazunart Yamaguchi, Toshiki Watanabe, Ayako Ono, Koichi Yoshimura, Makoto Shirao, Norio Miyata An atypical Leber’s hereditary optic neuropathy with the 11778 mutation Yoshihiro Hotta, Mutsuko Hayakawa, Keiko Fujiki, Koutaro Shinohara, Kazushige Sado, Atsushi Kanai, Kenji Yanashima A cranial nerve palsy associated with Mycoplasma pneumoniae infection C G Fink, L Butler Topical chemotherapy for conjunctival melanoma Paul T Finger, Mark S Milner, Steven A McCormick History of ophthalmology Letters to the editor Notices Instructions for authors No 12 DECEMBER 1993 Editorials The prospects of new treatment in age-related macular degeneration J H Chisholm Choice in local anaesthesia Christopher Liu, Richard Redmond Original articles — Clinical science Treatment of choroidal neovascularisation in age-related macular degeneration with interferon alfa-2a and alfa-2b Mark C Gillies, John P Sarks, Paul E Beaumont, Alex B Hunyor, David McKay, Margaret Kearns, Peter 7M cClusky, Shirley H Sarks Clinical experience with interferon alfa-2a for exudative age-related macular degeneration 7 N P Kirkpatrick, A D Dick, J V Forrester Regional anaesthesia for cataract surgery: comparison of three techniques Timo Ali-Melkkild, Markku Virkkild, Kan Leino, Heikki Palve Optociliary veins and central retinal vein occlusion Giuseppe Giuffré, Carlo Palumbo, Gaetano Randazzo-Papa Electrophysiology of type [I mesangiocapillary glomerulonephritis with associated fundus abnormalities C O’Brien, 7 Duvall-Young, M Brown, C Short, M Bone Prognostic value of carotid ultrasound lesion morphology in retinal ischaemia: result of a long term follow up C M O'Farrell, D E FitzGerald Ophthalmic results in patients with macroprolactinomas treated with a new prolactin inhibitorC V 205-502 Michéle Grochowicki, Yad Khalfallah, Alain Vighetto, Serge Berquet, Genevieve Sassolas he frequency and clinical significance of bone involvement in outer canthus dermoid cysts N Sathananthan, I F Moseley, G E Rose, 7 E Wright Laboratory science Cancer-associated retinopathy with retinal phlebitis Yoshitaka Ohnishi, Susumu Ohara, Tatji Sakamoto, Toshihtko Kohno, Fuminoni Nakao Immunohistochemical analysis of lattice corneal dystrophies types I and II Tero Kivela, Ahti Tarkkanen, Ian McLean, Forge Ghiso, Blas Frangione, Matti Haltia Perspective Applications of monoclonal antibodies in the investigation, diagnosis, ai.d treatment of retinoblastoJmoahn F Tarlton, DL Easty Case reports Manifesting heterozygosity in Norrie’s disease? G Woodruff, R Newbury-Ecob, D S Plaha, I D Young Pasteurella multocida conjunctivitis K Tharmaseelan, M S Morgan Phthirus pubis infestation of the eyelids Paul A Rundle, David S Hughes Subcutaneous neuroglial choristoma: an immunohistopathological case study Selwa A F Al-Hazzaa, Charles S Specht, Ian W McLean, Laurence A Somers Multicentric sebaceous gland carcinoma of the lid? Hubertus von Below, Geoffrey E Rose, Alison C E McCartney, John E Wright Therapeutic ptosis with botulinum toxin in epikeratoplasty Tim Freegard, lan Mackie, Chad Rostron Exotropia as a sign of myasthenia gravis in dysthyroid ophthalmology Marino E Vargas, Floyd A Warren, Mark F Kupersmith A rare case of orbital mucormycosis with gas gangrene panophthalmitis Vinod K Gupta, Waleed Al-Tuwarqui History of ophthalmology Letters to the editor Book reviews Notices Author Index Subject Index