British Journal of Clinical Pharmacology 2004: Vol 57 Table of Contents

2004·1.9 MB·English

Contents
Volume 57, Number 1, January 2004
Editors’ View 80 Quality of drug information on the World Wide Web
On Being 30: J.K. Aronson and strategies to improve pages with poor information
quality. An intervention study on pages about sildenafil:
Reviews M. Martin-Facklam, M. Kostrzewa, P. Martin &
Age-related changes in pharmacokinetics and WE. Haefeli
pharmacodynamics: basic principles and practical
applications: AA. Mangoni & S.H.D. Jackson
Therapeutics
Stroke, dementia, and drug delivery: G.A. Ford,
Differences between clinical trials and postmarketing
CA. Bryant, AA. Mangoni & S.H.D. Jackson use: K. Martin, B. Bégaud, P. Latry,
Vasopeptidase inhibitors: will they have a role in clinical
G. Miremont-Salamé, A. Fourrier & N. Moore
practice?: M./. Worthley, R.Corti & S.G. Worthley
Safety evaluation of fixed combination piperaquine plus
dihydroartemisinin (Artekin®) in Cambodian children
Pharmacodynamics
and adults with malaria: H. Karunajeewa, C. Lim,
Effects of passive smoking on blood pressure and
T-Y. Hung, K.F. lett, M.B. Denis, D. Socheat &
aortic pressure waveform in healthy young adults —
TM.E. Davis
influence of gender: A. Mahmud & J. Feely
Pharmacokinetics Short reports
Population pharmacokinetics of weekly docetaxel in Acute systemic effects of inhaled salbutamol in
patients with advanced cancer: K.A. Slaviero, SJ. Clarke, asthmatic subjects expressing common homozygous
AJ. McLachlan, E.Y.L. Blair & L.P. Rivory fB.-adrenoceptor haplotypes at positions 16 and 27:
Effect of age on the pharmacokinetics of duloxetine D.K.C. Lee, CE. Bates & BJ. Lipworth
in women: M.H. Skinner, H.-Y. Kuan, A. Skerjanec, Large interindividual variability in the in vitro formation
M.E. Seger, M. Heathman, L. O’Brien, S. Reddy & of tamoxifen metabolites related to the development
M.P. Knadler of genotoxicity: J.K. Coller, N. Krebsfaenger, K. Klein,
Elimination of ephedrines in urine following multiple R. Wolbold, A. Nussler, P. Neuhaus, U.M. Zanger,
dosing: the consequences for athletes, in relation to M. Eichelbaum & TE. Mirdter
doping control: V. Chester, D.R. Mottram, T. Reilly &
M. Powell Book reviews
Pharmacology, 5th edn: G. McLean
Pharmacogenetics Oxford Textbook of Clinical Pharmacology and Drug
The arginine-16 B,-adrenoceptor polymorphism Therapy: AJ. Smith
predisposes to bronchoprotective subsensitivity in The Regulation of Medical Products: N. Baber
patients treated with formoterol and salmeterol:
D.K.C. Lee, G.P. Currie, LP. Hall, JJ. Lima &
Letter to the Editor
BJ. Lipworth
Paediatric methylphenidate (Ritalin") restrictive
conditions of prescription in France: C. Frances,
Pharmacoepidemiology
G. Hoizey, H. Millart & T. Trenque
Clinical pharmacology studies in UK Phase 1 units:
an AHPPI survey 1999-2000: N. Calder, M. Boyce,
J. Posner & D. Sciberras Errata
Volume 57, Number 2, February 2004
Editors’ View 127 Application of data mining techniques in
119 In defence of polypharmacy: J.K. Aronson pharmacovigilance: A.M. Wilson, L. Thabane &
A. Holbrook
Reviews Pharmacokinetics
121 Adverse drug reactions in elderly patients: Comparative population pharmacokinetics of lorazepam
PA. Routledge, M.S. O'Mahony & K.W. Woodhouse and midazolam during long-term continuous infusion in
Contents
Volume 57, Number 1, January 2004
Editors’ View 80 Quality of drug information on the World Wide Web
On Being 30: J.K. Aronson and strategies to improve pages with poor information
quality. An intervention study on pages about sildenafil:
Reviews M. Martin-Facklam, M. Kostrzewa, P. Martin &
Age-related changes in pharmacokinetics and WE. Haefeli
pharmacodynamics: basic principles and practical
applications: AA. Mangoni & S.H.D. Jackson
Therapeutics
Stroke, dementia, and drug delivery: G.A. Ford,
Differences between clinical trials and postmarketing
CA. Bryant, AA. Mangoni & S.H.D. Jackson use: K. Martin, B. Bégaud, P. Latry,
Vasopeptidase inhibitors: will they have a role in clinical
G. Miremont-Salamé, A. Fourrier & N. Moore
practice?: M./. Worthley, R.Corti & S.G. Worthley
Safety evaluation of fixed combination piperaquine plus
dihydroartemisinin (Artekin®) in Cambodian children
Pharmacodynamics
and adults with malaria: H. Karunajeewa, C. Lim,
Effects of passive smoking on blood pressure and
T-Y. Hung, K.F. lett, M.B. Denis, D. Socheat &
aortic pressure waveform in healthy young adults —
TM.E. Davis
influence of gender: A. Mahmud & J. Feely
Pharmacokinetics Short reports
Population pharmacokinetics of weekly docetaxel in Acute systemic effects of inhaled salbutamol in
patients with advanced cancer: K.A. Slaviero, SJ. Clarke, asthmatic subjects expressing common homozygous
AJ. McLachlan, E.Y.L. Blair & L.P. Rivory fB.-adrenoceptor haplotypes at positions 16 and 27:
Effect of age on the pharmacokinetics of duloxetine D.K.C. Lee, CE. Bates & BJ. Lipworth
in women: M.H. Skinner, H.-Y. Kuan, A. Skerjanec, Large interindividual variability in the in vitro formation
M.E. Seger, M. Heathman, L. O’Brien, S. Reddy & of tamoxifen metabolites related to the development
M.P. Knadler of genotoxicity: J.K. Coller, N. Krebsfaenger, K. Klein,
Elimination of ephedrines in urine following multiple R. Wolbold, A. Nussler, P. Neuhaus, U.M. Zanger,
dosing: the consequences for athletes, in relation to M. Eichelbaum & TE. Mirdter
doping control: V. Chester, D.R. Mottram, T. Reilly &
M. Powell Book reviews
Pharmacology, 5th edn: G. McLean
Pharmacogenetics Oxford Textbook of Clinical Pharmacology and Drug
The arginine-16 B,-adrenoceptor polymorphism Therapy: AJ. Smith
predisposes to bronchoprotective subsensitivity in The Regulation of Medical Products: N. Baber
patients treated with formoterol and salmeterol:
D.K.C. Lee, G.P. Currie, LP. Hall, JJ. Lima &
Letter to the Editor
BJ. Lipworth
Paediatric methylphenidate (Ritalin") restrictive
conditions of prescription in France: C. Frances,
Pharmacoepidemiology
G. Hoizey, H. Millart & T. Trenque
Clinical pharmacology studies in UK Phase 1 units:
an AHPPI survey 1999-2000: N. Calder, M. Boyce,
J. Posner & D. Sciberras Errata
Volume 57, Number 2, February 2004
Editors’ View 127 Application of data mining techniques in
119 In defence of polypharmacy: J.K. Aronson pharmacovigilance: A.M. Wilson, L. Thabane &
A. Holbrook
Reviews Pharmacokinetics
121 Adverse drug reactions in elderly patients: Comparative population pharmacokinetics of lorazepam
PA. Routledge, M.S. O'Mahony & K.W. Woodhouse and midazolam during long-term continuous infusion in
critically ill patients: E.L. Swart, K.P. Zuideveld, toxicity: $.V. Morant, A.D. McMahon, J.G.F. Cleland,
J. de Jongh, M. Danhof, L.G. Thijs & P.G. Davey & TM. MacDonald
RM.J. Strack van Schijndel
Population pharmacokinetics of artemether and Data interpretation in drug development
dihydroartemisinin following single intramuscular dosing The influence of diet upon liver function tests and
of artemether in African children with severe falciparum serum lipids in healthy male volunteers resident in
malaria: S. Mithwani, L. Aarons, G.O. Kokwaro, a Phase | unit: L. Purkins, E.R. Love M.D. Eve,
O. Majid, S. Muchohi, G. Edwards, S. Mohamed, CL. Wooldridge, C. Cowan, TS. Smart, PJ. Johnson &
K. Marsh & W. Watkins W.G. Rapeport
Pharmacodynamics
Short reports
Modelling acute tolerance to the EEG effect of two
Sildenafil does not improve nitric oxide-mediated
benzodiazepines: H. /Ihmsen, S. Albrecht, W. Hering,
endothelium-dependent vascular responses in smokers:
J. Schittler & H. Schwilden
V. Dishy, PA. Harris, R. Pierce, H.C. Prasad,
G. Sofowora, H.L. Bonar, AJ.J. Wood & C.M. Stein
Pharmacokinetics and Pharmacodynamics
Protective role of glutathione S-transferase P1 (GSTP1)
Pharmacokinetic and pharmacodynamic assessment of
Vall05Val genotype in patients with bronchial asthma:
a five-probe metabolic cocktail for CYPs 1A2, 3A4,
A.S. Aynacioglu, M. Nacak, A. Filiz, E. Ekinci & |. Roots
2C9, 2D6 and 2E1: G.E. Blakey, J.A. Lockton, J. Perrett,
Effect of food on the relative bioavailability of two oral
P. Norwood, M. Russell, Z. Aherne & J. Plume
formulations of posaconazole in healthy adults:
Assessment of the relative in vivo potency of the
R. Courtney, D. Wexler, E. Radwanski, J. Lim &
hydroxylated metabolite of darifenacin in its ability to
M. Laughlin
decrease salivary flow using pooled population
pharmacokinetic-pharmacodynamic data: 7 Kerbusch,
Book review
PA. Milligan & M.O. Karlsson
Clinical Pharmacology: G. Shenfield
Drug interactions
Effect of rifampicin on pravastatin pharmacokinetics in Letter to the Editor
healthy subjects: C. Kyrklund, J.T. Backman, Cerebrospinal fluid pharmacokinetics of paracetamol
M. Neuvonen & PJ. Neuvonen after intravenous propacetamol in a preterm infant:
K. Allegaert, R. Verbesselt, H. Devlieger, J. de Hoon &
Pharmacoeconomics D. Tibboel
Cardiovascular prophylaxis with aspirin: costs of supply
and management of upper gastrointestinal and renal Errata
Volume 57, Number 3, March 2004
Editors’ View Concentration-time profile for perhexiline and
Rational prescribing, appropriate prescribing: J.K. Aronson hydroxyperhexiline in patients at steady state:
TE. Jones, R.G. Morris & J.D. Horowitz
Reviews Pharmacokinetic evaluation of a new oral sustained
Optimization of drug prescribing: S.H.D. Jackson, release dosage form of tramadol: H. Malonne,
AA. Mangoni & G.M. Batty B. Sonet, B. Streel, S. Lebrun, S. De Niet, A. Sereno &
Metabolic inertia in contracting skeletal muscle: F. Vanderbist
a novel approach for pharmacological intervention in The effect of rosuvastatin on oestrogen & progestin
peripheral vascular disease: PL. Greenhaff pharmacokinetics in healthy women taking an oral
S.P. Campbell-O’Sullivan, D. Constantin-Teodosiu, contraceptive: S.G. Simonson, P.D. Martin, MJ. Warwick,
S.M. Poucher, PA. Roberts & J.A. Timmons PD. Mitchell, & D.W. Schneck
Pharmacokinetics Drug metabolism
Oral contraception does not alter single dose saquinavir CYP2D6 and CYP3A4 involvement in the primary
pharmacokinetics in women: M. Fréhlich, J. Burhenne, oxidative metabolism of hydrocodone by human liver
M. Martin-Facklam, J. Weiss, M. von Wolff. T. Strowitzki, microsomes: M.R. Hutchinson, A. Menelaou,
|. Walter-Sack & WE. Haefeli D.J.R. Foster, J.K. Coller & AAA. Somogyi
Population pharmacokinetics of piperaquine in adults
and children with uncomplicated falciparum or vivax Drug distribution
malaria: T-¥ Hung, TM.E. Davis, K.F. llett Factors affecting variability in distribution of tacrolimus
H. Karungjeewa, S. Hewitt, M.B. Denis, C. Lim & in liver transplant recipients: H. Zahir, G. McCaughan,
D. Socheat M. Gleeson, RA. Nand & AJ. McLachlan
Education Short reports
Impact of a short postgraduate course in rational Influence of mild liver impairment on the
pharmacotherapy for general practitioners: A. Akici, pharmacokinetics of tezosentan, a drug excreted
S. Kalaca, M.U. Ugurlu, A. Karaalp, A. Cali & U. Oktay unchanged into bile: J. Dingemanse &
PLM. van Giersbergen
Drug Utilisation Tizanidine is mainly metabolized by cytochrome P450
Trends in accessibility to medicines for children in New 1A2 in vitro: M.T. Granfors, J.T. Backman, J. Laitila &
Zealand: 1998-2002: J. Chui, J. Tordoff, J. Kennedy, & PJ. Neuvonen
D. Reith
Book review
Therapeutics Experimental Therapeutics: edited by M.R. Wilkins;
The effect of hypertension and hypercholesterolemia reviewed by J.M. Ritter
screening with subsequent intervention letter on the
use of blood pressure and lipid lowering drugs: Abstracts
J. Atthobari, T.B.M. Monster, PE. de Jong, L.TW. de Proceedings of the Dutch Society for Clinical
Jong-van den Berg for the Prevend Study Group Pharmacology and Biopharmacy, 11 April 2003
Have COX-2 inhibitors influenced the co-prescription of
anti-ulcer drugs with NSAIDs?: M. Teeling, K. Bennett &
J. Feely
Volume 57, Number 4, April 2004
Editors’ View Drug Disposition
Drug interactions — information, education, and the Biood—brain barrier transport of morphine in patients
British National Formulary: J.K. Aronson with severe brain trauma: P Ederoth, K. Tunblad,
R. Bouw, CJ.F. Lundberg, U. Ungerstedt
Reviews C.-H. Nordstr6m & M. Hammarlund-Udenaes
Recent advances in drug action and therapeutics:
Relevance of novel concepts in G-protein-coupled Drug Interactions
receptor and signal transduction pharmacology: Therapeutic drug monitoring of lopinavir/ritonavir given
CB. Brink, B.H. Harvey, J. Bodenstein, D.P. Venter & alone or with a non-nucleoside reverse transcriptase
D.W. Oliver inhibitor: C. Solas, |. Poizot-Martin, M.-P. Drogoul,
|. Ravaux, C. Dhiver, A. Lafeuillade, T. Allegre,
Pharmacodynamics M. Mokhtari, J. Moreau, G. Lepeu, N. Petit, A. Durand
The presence of ernphysema does not affect the & B. Lacarelle
systemic bioactivity of inhaled fluticasone in severe The CYP2C8 inhibitor trimethoprim increases the
chronic obstructive pulmonary disease: D.K.C. Lee & plasma concentrations of repaglinide in healthy
BJ. Lipworth subjects: M. Niemi, L.l. Kajosaari, M. Neuvonen,
Effects of a nonpeptide motilin receptor antagonist on J.T. Backman & PJ. Neuvonen
proximal gastric motor function: /.M.C. Kamerling, Effects of grapefruit juice on pharmacokinetics of
A.D. van Haarst, J. Burggraaf, R.C. Schoemaker, atorvastatin and pravastatin in Japanese: /. Fukazawa,
M.L. de Kam, H. Heinzerling, A.F. Cohen & N. Uchida, E. Uchida & H. Yasuhara
AA.M. Masclee Clinical inhibition of CYP2D6-catalysed metabolism
by the antianginal agent perhexiline: BJ.L. Davies,
Pharmacokinetics J.K. Coller, H.M. James, D. Gillis, AA. Somogyi,
Retrospective population pharmacokinetic analysis of J.D. Horowitz, R.G. Morris & B.C. Sallustio
cetirizine in children aged 6 months to 12 years: Potential for drug interactions involving cytochromes
M. Pitsiu, Z. Hussein, O. Majid, L. Aarons, P450 2D6 and 3A4 on general adult psychiatric and
M. de Longueville & A. Stockis functional elderly psychiatric wards: S.C. Davies,
Pharmacokinetics of levosimendan and its circulating S. Eayrs, P. Pratt & M.S. Lennard
metabolites in patients with heart failure after an Database analyses for the prediction of in vivo
extended continuous infusion of levosimendan: drug—drug interactions from in vitro data: K. Ito,
S. Antila, M. Kivikko, L. Lehtonen, J. Eha, A. Heikkilé, H.S. Brown & J.B. Houston
P. Pohjanjousi & P.J. Pentikdinen Different inhibitory effect of fluvoxamine on
Population pharmacokinetics of raltitrexed in patients omeprazole metabolism between CYP2C19 genotypes:
with advanced solid tumours: E.¥.L. Blair, L.P. Rivory, N. Yasui-Furukori, T. Takahata, T. Nakagami, G. Yoshiya,
SJ. Clarke & AJ. McLachlan ¥. Inoue, S. Kaneko & T. Tateishi
495 Effect of St John’s Wort on the activities of CYP1A2, acute care government funded hospitals: MJ. Dooley,
CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine K.M. Allen, CJ. Doecke, K.J. Galbraith, G.R. Taylor,
oxidase in healthy males and females: M. Wenk, J. Bright & D.L. Carey
L. Todesco & S. Krahenbihl
Short reports
Prescribing Overanticoagulation associated with combined use of
500 Acute otitis media in children: a retrospective analysis lactulose and acenocoumarol or phenprocoumon:
of physician prescribing patterns: C. Quach, J.-P. Collet L.E. Visser, F.J.A. Penning-van Beest, J.H.P. Wilson,
& J. LeLorier A.G. Vulto, AA.H. Kasbergen, PA.G.M. De Smet,
A. Hofman & B.H. Stricker
Pharmacovigilance Professional athletes suffering from familial
Low body mass index is associated with an increased hypercholesterolaemia rarely tolerate statin treatment
risk of neuropsychiatric adverse events and because of muscular problems: H. Sinzinger &
concentration impairment in women on mefloquine: J. O'Grady
M.M. van Riemsdijk, M.C.J.M. Sturkenboom, J.M. Ditters, Protein binding and o:8 anomer ratio of
J.H.M. Tulen, RJ. Ligthelm, D. Overbosch & B.H. Stricker dihydroartemisinin in vivo: K.T. Batty, K.F. llett &
TM.E. Davis
Pharmacoeconomics Notice of future meetings
A prospective multicentre study of pharmacist initiated
changes to drug therapy and patient management in
Volume 57, Number 5, May 2004
Editor's View patients undergoing in vitro fertilization and embryo
5355 Characterizing variability in cardiovascular drug transfer: I. Goggin, Q.TX. Nguyen & A. Munafo
responses: R. Donnelly
Pharmacokinetics/pharmacodynamics
Editor's report Single-dose FTY720 pharmacokinetics, food effect,
The British Journal of Clinical Pharmacology Editors’ and pharmacological responses in healthy subjects:
Report for 2003: J.K. Aronson, M.S. Lennard, J.M. Ritter, J.M. Kovarik, R. Schmouder, D. Barilla, ¥. Wang &
N.S. Baber & EJ. Begg G. Kraus
Review Drug interactions
Drug metabolism and ageing: M.T. Kinirons & Effect of St John’s wort and ginseng on the
M.S. O'Mahony pharmacokinetics and pharmacodynamics of warfarin in
healthy subjects: X. Jiang, K.M. Williams, WS. Liauw,
Pharmacodynamics AJ. Ammit, B.D. Roufogalis, CC. Duke, R.O. Day &
The |,-imidazoline agonist moxonidine decreases AJ. McLachlan
sympathetic tone under physical and mental stress:
RR. Wenzel, A. Mitchell, W. Siffert. S. Bihrmann, Drug distribution
T. Philipp & RF. Schdfers The effect of quinidine, used as a probe for the
Modelling the cardiovascular effects of ephedrine: involvement of P-glycoprotein, on the intestinal
A.M. Persky, N.S. Berry, G.M. Pollack & absorption and pharmacodynamics of methadone:
K.L.R. Brouwer E.D. Kharasch, C. Hoffer & D. Whittington
Pharmacokinetics Adverse drug reactions
Tissue pharmacokinetics of levofloxacin in human Frequency and characteristics of hospital admissions
soft tissue infections: R. Bellmann, G. Kuchling, associated with drug-related problems in paediatrics:
P. Dehghanyar, M. Zeitlinger, E. Minar, B.X. Mayer, K.L. Easton, C.B. Chapman & J.E. Brien
M. Miller & C. Joukhadar A comparison of three different sources of data in
Effects of various factors on steady-state plasma assessing the frequencies of adverse reactions to
concentrations of risperidone and 9-hydroxyrisperidone: amiodarone: ¥.K. Loke, S. Derry & J.K. Aronson
lack of impact of MDR-1 genotypes: NV. Yasui-Furukori,
K. Mihara, T. Takahata, A. Suzuki, T- Nakagami, Therapeutics
R. De Vries, T. Tateishi, T Kondo & S. Kaneko Furosemide responsiveness, non-adherence and
Population pharmacokinetic modelling of Emfilermin resistance during the chronic treatment of heart failure:
(recombinant human leukaemia inhibitory factor, r-hLiF) a longitudinal study: RJ. MacFadyen, J.C. Gorski,
in healthy postmenopausal women and in infertile D.C. Brater & A.D. Struthers
632 Comparison of once-daily nifedipine controlled-release Book reviews
with twice-daily nifedipine retard in the treatment of The Maudsley 2003 Prescribing Guidelines, 7th edition:
essential hypertension: J. Minami, A. Numabe, edited by D. Taylor, C. Paton & R. Kerwin; reviewed by
N. Andoh, N. Kobayashi, S. Horinaka, T. Ishimitsu & E. Szabadi
H. Matsuoka The Practice of Medicinal Chemistry: edited by C.G.
Meta-analysis of large randomized controlled trials to Wermuth,; reviewed by P. Jeffrey
evaluate the impact of statins on cardiovascular
outcomes: B.M.Y. Cheung, IJ. Lauder, C-P. Lau & Letters to the editor
CR. Kumana 663 Genotyping of the A6986G polymorphism of CYP3A5:
J. Weiss & WE. Haefeli
Short reports 664 CYP3A5 phenotype-genotype correlations in a British
Effect of duloxetine on tolterodine pharmacokinetics in population: A.K. Daly & B.P. King
healthy volunteers: ZC. Hua, A. Pan, C. Chan, ¥.K. Poo,
M.H. Skinner, M.P. Knadler, CR. Gonzales & S.D. Wise 664 Erratum
An investigation of components of variance and
tachyphylaxis in a placebo-controlled intravenous 665 Proceedings of the British Pharmacological Society
tyramine study: M.V. Cantarini, CL. Watkins, J. Growcott Clinical Pharmacology Section 16-18 December 2003
& AM. Hughes
Volume 57, Number 6, June 2004
Editors’ View Population pharmacokinetics of total and unbound
On the waterfront — the breadth and depth of clinical plasma cisplatin in adult patients: S. Urien & F. Lokiec
pharmacology: J.K. Aronson 764 Maximum a posterior! Bayesian estimation of epirubicin
clearance by limited sampling: L.D. Ralph,
Review A.H. Thomson, N.A. Dobbs & C. Twelves
The revision of the Declaration of Helsinki: past,
present and future: R.V. Carlson, K.M. Boyd & Pharmacokinetics/Pharmacodynamics
DJ. Webb The effects of renal impairment on the
pharmacokinetics and safety of fosfluconazole and
Pharmacodynamics fluconazole following a single intravenous bolus
Effects of single or combined histamine H,-receptor injection of fosfluconazole: S. Sobue, K. Tan, G. Layton,
and leukotriene CysLT,-receptor antagonism on nasal V. Leclerc & A. Weil
adenosine monophosphate challenge in persistent
allergic rhinitis: D.K.C. Lee, CM. Jackson, P.-C. Soutar, Pharmacogenetics
T.-C. Fardon & BJ. Lipworth Relationship between Type A and Bp ersonality and
Endothelins and their inhibition in the human skin debrisoquine hydroxylation capacity: SH. Gan, R. Ismail,
microcirculation: ET,,_;;, a mew vasoconstrictor peptide: WA.W. Adnan, W. Zulmi, N. Kumaraswamy &
SJ. Leslie, M.Q. Rahman, M.A. Denvir, D.E. Newby & E.T. Larmie
DJ. Webb
The calcimimetic agent KRN 1493 lowers plasma Therapeutics
parathyroid hormone and ionized calcium Leflunomide in active rheumatoid arthritis: a
concentrations in patients with chronic renal failure on prospective study in daily practice: E.N. Van Roon,
haemodialysis both on the day of haemodialysis and T.L.TH.A. Jansen, L. Mourad, PM. Houtman,
on the day without haemodialysis: N. Ohashi, G.A.W. Bruyn, E.N. Griep, B. Wilffert H. Tobi &
T. Uematsu, S. Nagashima, M. Kanamaru, A. Togawa, J.R.B.J. Brouwers
A. Hishida, E. Uchida, T. Akizawa & S. Koshikawa Stroke prevention and atrial fibrillation: reasons leading
to an inappropriate management. Main results of the
Pharmacokinetics SAFE II study: D. Deplanque, D. Leys, L. Parnetti,
Population pharmacokinetics of pyrimethamine and R. Schmidt, J. Ferro, J.D. Reuck, J.-L. Mas, V. Gallai &
sulfadoxine in children with congenital toxoplasmosis: the SAFE Il Investigators
T. Trenque, N. Simon, |. Villena, C. Chemia, C. Quereux,
B. Leroux, R. Jaussaud, G. Rémy, D. Dupouy, H. Millart, Adverse Drug Reactions
J.-M. Pinon & S. Urien Subclinical alteration of taste sensitivity induced by
Population pharmacokinetics of (R)-, (S)- and candesartan in healthy subjects: S. 7suruoka,
rac- methadone in methadone maintenance patients: M. Wakaumi, K. Nishiki, N. Araki, K. Harada,
D.J.R. Foster, AA. Somogyi, J.M. White & F Bochner K. Sugimoto & A. Fujimura
Short Reports Book Review
813 Bisphosphonate use and subsequent prescription of 818 Handbook of Drug Interactions. A Clinical and Forensic
acid suppressants: E.E. Roughead, K. McGeechan & Guide: edited by A. Mozayani, L.P. Raymon; reviewed
G.P. Sayer by RJ. Flanagan
Announcements
Letter to the Editors 819 11-14 September 2005 Ninth International Conference
817 Quinine intoxications: a continuing problem: S. Taylor on Endothelin (ET-9)
817 Author's reply: NJ. Langford, AM. Good, WJ. Laing &
D.N. Bateman 820 Indices for Volume 57