British Journal of Clinical Pharmacology 2003: Vol 55 Table of Contents

9 Pages·2003·2.4 MB·English

The British Journal of
Clinical Pharmacology
Volume 55
2003
Published for
The British Pharmacological Society by
Blackwell Publishing
© 2003, Blackwell Publishing Ltd
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Contents
This article is considered particularly suitable for continuing medical education.
Volume 55, Number 1, January 2003
Viewpoint Polymorphisms in the cytochrome P450 CYP1A2 gene
Good clinical practice: a nuisance, a help or a necessity (CYPIA2) in colorectal cancer patients and controls:
for clinical pharmacology?:J . Sweatinan allele frequencies, linkage disequilibrium and influence
on caffeine metabolism: C. Sachse, U. Bhambra, G. Smith,
Pharmacokinetics TJ. Lightfoot, J.H. Barrett,J . Scollay, R.C. Garner,
Pharmacokinetics of oral betaine in healthy subjects and 1.R. Boobis, C.R. Wolf & N.J. Gooderham
patients with homocystinuria: B.C. Sclwahn, D. Hafner,
[? Holilfeld, N. Balkenhol, M.D. Laryea & U. Wendel Drug Disposition
Rectal ropivacaine is absorbed proportionally to the dose, Diabetes mellitus increases the in vivo activity of
with low intraindividual variability: E. Arlander, J. Sjévall, cytochrome P450 2E1 in humans: Z. Wang, S.D. Hall,
J. Sorstad, C. Norsten-Ho6g & L.L. Gustafsson J.-E Maya, L. Li, A. Asghar & J.C. Gorski
Population pharmacokinetics of theophylline during
paediatric extracorporeal membrane oxygenation: Drug Interactions
H. Mulla, E Nabi, S. Nichani, G. Lawson, R.K. Firmin & Effect of the CYP3A4 inhibitor erythromycin on the
D.R. Upton pharmacokinetics of lignocaine and its pharmacologically
Population pharmacokinetic analysis of meloxicam in active metabolites in subjects with normal and impaired
rheumatoid arthritis patients: I. Meineke & D. Tiirck liver function: R. Orlando, P. Piccoli, S. De Martin,
R. Padrini & P. Palatini
Lack of effect of ketoconazole on the pharmacokinetics
Pharmacodynamics
of rosuvastatin in healthy subjects: K.J. Cooper, PD. Martin,
Biomarkers for the effects of benzodiazepines in healthy
A.L. Dane, M.J. Wanvick,A . Raza & D.Wé. Schneck
volunteers: S.J. de Visser, J.P van der Post, PP. de Waal,
Pharmacokinetic interaction between amprenavir and
FE. Cornet, ALE Cohen & J.M.A,. van Gerven
delavirdine after multiple-dose administration in healthy
volunteers: U.S. Justesen, N.A. Klitgaard, K. Brosen &
Pharmacokinetics/pharmacodynamics C. Pedersen
Pharmacokinetics of diclofenac and inhibition of
cyclooxygenases | and 2: no relationship to the CYP2C9 Short report
genetic polymorphism in humans:J . Kirchheiner, MMR vaccine and idiopathic thrombocytopaeni
I. Meineke, N. Steinbach, C. Meisel, I. Roots & J. Brockmoller purpura:
C. Black, JA. Kaye & H. Jick
Pharmacogenetics
NAT2 and CYP1A2 phenotyping with caffeine: Letter
head-to-head comparison of AFMU vs. AAMU in the Unwanted pregnancy on self-medication with St John’s
urine metabolite ratios: A. Nyéki, T? Buclin,J . Biollaz & wort despite hormonal contraception: ULI. Schivarz,
L.A. Decosterd B. Biischel & Wo Kirch
Volume 55, Number 2, February 2003
Pharmacokinetics Differential effects of carvedilol and atenolol on plasma
Pharmacokinetics, food intake requirements and noradrenaline during exercise in humans: R.B. Herman,
tolerability of once-daily combinations of nelfinavir and PJ. Jesudason, A.M. Mustafa, R. Husain, A.M.J. Choy &
low-dose ritonavir in healthy volunteers: R.E. Aarnoutse, C.C. Lang
J.A.H. Droste, J.J.G. van Oosterhout, PP Koopmans, Blood pressure response to conventional and low-dose
M. Popescu, P. Reiss, ¥.A. Hekster & D.M. Burger enalapril in chronic renal failure: 7? Elung-Jensen,
J. Heisterberg, A.-L. Kamper,J . Sonne & S. Strandgaard
Pharmacodynamics
Comparative study of analgesic efficacy and morphine- Pharmacokinetics/Pharmacodynamics
sparing effect of intramuscular dexketoprofen trometamol Population PKPD modelling of the long-term
with ketoprofen or placebo after major orthopaedic hypoglycaemic effect of gliclazide given as a once-a-day
surgery: M.H. Hanna, K.M. Elliott, ME. Stuart- Taylor, modified release (MR) formulation: N. Frey, C. Laveille,
D.R. Roberts, D. Buggy & G.J. Arthurs M. Paraire, M. Francillard, N.H.G. Holford & R. Jochemsen
Pharmacogenetics 19] Interaction of ibuprofen and probenecid with drug
Slow acetylator phenotype and genotype in HIV-positive metabolizing enzyme phenotyping procedures using
patients with sulphamethoxazole hypersensitivity: caffeine as the probe drug: F | tic, WE. Haefeli, J. Drewe,
ilar, Ed G.L. Wilkins, S. Krahenbiihl & VI. Wenk
Ettect of short-term administration of garlic supplements
on single-dose ritonavir pharmacokinetics in healthy
Pharmacovigilance volunteers: K. Gallicano, B. Foster & S. Choudhri
ofile of rofecoxib as used in general practice in Alterations in cyclosporin A pharmacokinetics and
scription event monitoring study metabolism during treatment with St John’s wort in renal
Wilton & S.A.W Shaki transplant patients: S. Bauer, E. Stormer, A . JJ ohne,
H. Kriiger, K. Budde, H.-H. Neum yer, 1. Roots & 1. Vai
Drug Disposition
\ com} irison of 1 lative ibundance, activity factor and
nh=i bitorv monox ke Mal inti1b ody ipproaches in th' e Short reports
rization of human CYP enzymolo1 gy VLG Soa Low-dose atorvastatin therapy does not augment
wis> & R.fp. Ril endothelial function in active hypercholesterolaemic
t
males: M.M. Parnell, J. PF Chin-Dusting, J. Start
Drug Interactions D.M. Kay
The ettect of |k etoconazole on the i ) mMtestinal \ population-based study of maternal use of amoxicillin
fexofenadine using a regional perfusion ind pregnancy outcome in Denmark: P Jepsen,
| utson,| Knut On « M.V. Skriver, A. Floyd, L. Lip H.( Schonheyder é
H.T. Sorensen
Volume 55, Number 3, March 2003
Editor’s View Drug Disposition
Features of this month The distribution and gender difference of CYP3A activity
in Chinese subjects: B Zhu, Z.-Q. Liu, G.-L. Chen,
Editorial
X.-P Chen, D.-S. Ou- Yang, I mg, S.-L. Huang,
( ymplemen ines clinical pharmacology and Z.-R lan é H.-H. Zhou
therapeuti
Phenotyping CYP3A using midazolam in cancer and
Review Article noncancer Asian patients: H.S. | B.C. Goh, L. Fan,
Quality, efficacy and safety of complementary medicines YM. Khoo, L. Wang, R. Lim, A B. Ong & C. Chita
tashions, facts and the future Part I. Regulation and
quality J. Bari Pharmacogenetics
Arylamine N-acetyltransferas¢ enotypes in the
Clinical Toxicology Thai population: 17 Kukong 1] { Prawan,
Glutathione, glutathione-dependent e1 IZVMICS and We Tas aneyakul, |. Aiemsa-ard
mMuoNidant status in erythrocytes from children treated
vith high-dos« parac ‘ ol: | ozer, S. Evar ,_]. Barr, Therapeutics
I. Soriar Pet Aspirin for the prevention of cardiovascular disease:
calculating benefit and harm in th¢ individual patient:
Y.K. Loke, A. Bell & S. Dern
Pharmacokinetics
Who receives lipid-lowering drugs: the effects of
Pharmacokinetics of vanadium in humans aftet
intravenous administration of i vanadium containing comorbidities and patient charact ristics on treatment
initiation: C.-C Yang, S.S. Jick & M.A. Testa
wbumin solution: G. Heinemann, B. Fichtl & W. Voet
Pharmacodynamics Clinical Trial Design
a
Comparative effect of human solubk insulin and insulin Planning and monitoring of plac« controlled survival
ispart upon hypogly 1ema-indu ed alterations in cardia¢ trials: comparison of the triangular test with usual interim
repolarization: R.T/C.1 Robin On, N.D. Harris, inalyses methods: J.-S. Hulot, M. Cucherat, A. Charlesworth,
R.H. Ireland, A. Lindl S.R Heller D.J. Van Veldhuisen, J.-C Corvol, A Viallet, J.-P. Boissel,
J. Hampton & P. Lechat
Pharmacokinetics/Pharmacodynamics
Population pharmacokinetics and concentration—eftect Short Reports
relationships of capecitabine metabolites in colorectal Low blood selenium concentrations in schizophrenic
mcer patients: R. Gir hke, H.-l Burger, B. Reigner, patients on clozapine: K.S. Vaddadi, I Soosat ¢
K.S. Blesch & [.-l Stemmel G. Vaddadi
Systemic bioactivity of intranasal triamcinolone and Genotyping of four genetic polymorphisms in the
mometasone in perennial allergic rhinitis: D.K.C. Lee, CYPIA2 gene in the Egyptian population: S.J. Hamdy,
EM. Robb, E.J. Sims, G.P Currie, L.C. McFarlane & M. Hiratsuka, K. Narahara, N. Endo, M. El-Enany,
B.J. Lipworth N. Moursi, M.S-E. Ahmed & M. Mizugaki
A placebo-controlled pharmacodynamic and
pharmacokinetic interaction study between tamsulosin
and acenocoumarol: P Rolan, I,J. Terpstra, C. Clarke, Letters to the Editers
FE Mullins & J.N. Visser Concomitant overdosing of other drugs in patients with
Development, implementation and cost-effectiveness of a paracetamol poisoning: G.K. Isbister, ILM. Whyte,
protocol for review of combination diuretic prescribing: FE. Downes, A.H. Dawson & P. McGettigan
J.D. Morgan, D.J. Wright, H. Chrystyn, B. George, Concomitant overdosing of other drugs in patients with
1.C. Booth & D.J. Shoesmith paracetamol poisoning: L.E. Schmidt & K. Dalhoff
Volume 55, Number 4, April 2003
Editor’s View Pharmacokinetics/pharmacodynamics
Features of this month’s Journal: [.K. Aronson Pharmacokinetics and systemic effects of inhaled
fluticasone propionate in chronic obstructive pulmonary
disease: S.D. Singh, C. Whale, N. Houghton, P- Daley- Yates,
S.M. Kirby & A.A. Woodcock
Editor’s Report
Time effects of food intake on the pharmacokinetics and
The British Journal of Clinical Pharmacology Editors’ Report
pharmacodynamics of quazepam: N. Yasui-Furukori,
for 2002: J.K. Aronson, M.S. Lennard, ].M. Ritter,
T. Takahata, TI; Kondo, K. Mihara, S. Kaneko, &
N.S. Baber, E.J. Begg
T. Tateishi
Pharmacoepidemiology
Review Undertreatment of hypercholesterolaemia: a population-
Quality, efficacy and safety of complementary medicines: based study: A.K. Mantel-Teeuwisse, WM.M. Verschuren,
fashions, facts and the future. Part II: Efficacy and safety: O.H. Klungel, D. Kromhout, A.D. Lindemans,J . Avorn,
J. Barnes A.J. Porsius & A. de Boe
Clinical Toxicology
Valproate overdose: a comparative cohort study of self
Pharmacodynamics
poisonings: G.K. Isbister, C.R. Balit, 1M. Whyte ¢
Bronchodilator effects of intravenous olprinone, a
A. Dawson
phosphodiesterase 3 inhibitor, with and without
aminophIy lline in asthmatic Ip atients: S. Myo) u, M. Fujimura, Therapeutics
Y. Kamio, T. Hirose, IT. Kita, H. Tachibana, Y. Ishiura,
A randomized, double-blind crossover trial of paracetamol
K. Watanabe, T; Hashimoto & S. Nakao
1000 mg four times daily vs ibuprofen 600 mg: effect on
Influence of captopril on symptomatic and hormonal
swelling and other postoperative events after third molar
responses to hypoglycaemia in humans: K.M. Oltmanns,
surgery: G.A. Bjornsson, H.R. Haanas © L.A. Skoglund
E. Deininger, P Wellhoener, B. Schultes, Wo Kern, E. Marx,
P. Doeminiak,J . Born, H.L. Fehim & A. Peters
Letters to the Editors
An evaluation of short-term corticosteroid response 1n
A life-threatening interaction between lithium and
perennial allergic rhinitis using histamine and adenosine
celecoxib: L. Slordal, S. Samstad, ]. Bathen & O. Spigset
monophosphate nasal challenge: A.M. Wilson, E.J. Sims,
Common mutant alleles of CYP2D6 causing the defect
L.C. Orr, E Robb & BJ. Lipworth
of CYP2D6 enzyme activity in a Japanese population:
1. Ishiguro, I: Kubota, H. Sasaki, ¥. Yamada & T? Iga
Antiepileptic drug hypersensitivity syndrome in a patient
Pharmacokinetics treated with valproate: J.C. Arévalo-Lorido,
Pharmacokinetics of ribavirin in combined interferon J. Carretero-Gomez, J.C. Bureo-Dacal, C. Montero-Leal &
alpha 2b and ribavirin therapy for chronic hepatitis P Bureo-Dacal
C virus infection: A. Tsubota, ¥. Hirose, N. Izumi é
H. Kumada Erratum
The pharmacokinetics of pioglitazone in patients with
impaired renal function: K. Budde, H.-H. Neumayer, Proceedings of the British Pharmacological Society Clinical
L. Fritsche, W. Sulowicz, 12 Stompér & D. Eckland Pharmacology Section 7-10 January 2003
Volume 55, Number 5, May 2003
Proceedings of the Festschrift in Honour of $73 The role of clinical pharmacology in optimizing
Professor Alasdair M. Breckenridge antiretroviral therapy: D.J. Back & S.H. Khoo
177
$51 Protessor Alasdair Muir Breckenridge CBE NHS R & D achievements and future challenges:
453 A tarewell to Alasdan K.L. Woods
458 Progress in clinical pharmacology over the last 20 years 180) Training prescribers: past, present and future: M. Pearson
Vl. Eichelbaun $83 Clinical pharmacology and therapeutics into the future:
160 Management of severe malaria: implications for research: V.D. Rawlin
K. Mars! 4186 Adverse drug reactions: back to the future: M. Pirmohamed
464. The contribution of clinical pharmacology to antimalarial & B.K. Park
drug discovery and development: P Winstanle)
$69 Clinical trials of antiretroviral drugs: the role of the
MRC AIDS Therapeutic Trials Committee (ATTC) and
the MRC Clinical Trials Unit (CTL |. Darbyshire
Volume 55, Number 6, June 2003
Editor’s View Pharmacokinetics
$193 Features of this month’s Journal: J.K. Aronson Population pharmacokinetics of levosimendan in patients
with congestive heart failure: E.N. Jonsson, S. Antila,
Editorial L. McFadyen, L. Lehtonen & M.O. Karlsson
195 Making tomorrow's doctors better prescribers Population pharmacokinetics of netilmicin in short-term
V.D. Rawlin prophylactic treatment: N. Jaure¢ , LA. Wald,
1. Astobieta, J.M.R. Sasiain, J.C. Lukas & R. Calvo
Special Article
496 Teaching safe and effective prescribing in UK medical
Pharmacogenetics
schools: a core curriculum for tomorrow’s doctors:
S. Maxwell & T Wa 560 Genotype and allele frequencies of TPMT, NAT2,
GST, SULTIAI and MDR-I in the Egyptian population:
Pharmacodynamics S.1. Hamdy, M. Hiratsuka, K. Narahara, N. Endo,
504 Effect of carbocysteine on cough reflex to capsaicin in VW. El-Enany, N. Moursi, M.S.-E. Ahmed& M. Mizugaki
isthmatic patients: Y. Ishiura, M. Fujimura, C. Yamamori,
K. Nobata, S. Myou, K. Kurashima, ¥. Michishita é
Drug Dispostion
I. Takegoshi
A novel metabolic pathway of morphine: formation of
511 Variability of heart rate correction methods for the QT
morphine glucosides in cancer patients: X.Y. Chen,
interval: M. Desai,L . Li, Z. Desta, M. Malik &
L.M. Zhao & D.E Zhong
D. Flockhart
Influence of age on the enantiomeric disposition of
518 Central nervous system effects of moxonidine
ibuprofen in healthy volunteers: S.C. ‘Tan, B.K. Patel,
experimental sustained release formulation in patients
S.H.D. Jackson, C.G. Swift & A.J. Hutt
with mild to moderate essential hypertension
M.J.B. Kemme, J.P vd Post, R.C. Schoemaker, M. Straub,
1.E Cohen & J.M.A. van Gerven Drug Interactions
526 C-peptide has no effect on forearm blood flow 588 Evidence of an interaction between nifedipine and
during local hyperinsulinaemia in healthy humans:
nafcillin in humans: C.C. Lang, S.K. Jamal, Z. Mohamed,
H. Langenberger, G. Schaller,J . Pleiner, EFM ittermayer,
VLR. Mustafa, A.M. Mustafa & T:C. Le
V1. Bayerle-Eder & M. Wolzt
531 Chronotherapy of high-dose active vitamin D3
in haemodialysis patients with secondary Pharmacovigilance
hyperparathyroidsm: a repeated dosing study: S. Tsuruoka, 591 Combined use of SSRIs and NSAIDs increases the
VI. Wakaumi, K. Sugimoto, T. Saito é risk of gastrointestinal adverse effects: J.C.E de Jong,
1. Fujimura PB. van den Berg, H. Tobi & L. TW. de Jong-van den Berg
The effect of motilin on the rectum in healthy 596 Effects of licence change on prescribing and poisons
volunteers: I.M.C. Kamerling,J . Burggraaf, A.D. van Haarst, enquiries for antipsychotic agents in England and
V.E Oppenhuizen-Duinker, H.C. Schoemaker, I. Biemond, Scotland: D.N. Bateman, A.M. Good, R. Afshari &
R. Jones, H. Heinzerling, A.E Cohen & A.A.M. Mascle C.A. Kelly
/
Pharmacoepidemiology CYP3A5 phenotype-genotype correlations in a British
Evidence for an age and gender bias in the secondary population: B.P King, J.B.S. Leathart, E. Mutch,
prevention of ischaemic heart disease in primary care: EM. Williams & A.K. Daly
D. Williams, K. Bennett & J. Feely Disposition of debrisoquine and nortriptyline in Korean
subjects in relation to CYP2D6 genotypes, and
Therapeutics comparison with Caucasians: P Dalén, M.-L. Dahil,
A proof of concept study to evaluate putative benefits H.-K. Roh, G. Tybring, M. Eichelbaum, G.R. Wilkinson &
of montelukast in moderate persistent asthmatics: L. Bertilsson
G.P. Currie, D.K.C. Lee, O.J. Dempsey, S.J. Fowler, Polymorphic hydroxylation of perhexiline in vitro:
L.M. Cowan & B.J. Lipworth L.B. Serensen, R.N. Sorensen, J.O. Miners, A.A. Somogyi,
N. Greurinovich & D.J. Birkett
Short Reports Phe effects of histamine and leukotriene receptor
Comparison of the micro- and macro-vascular effects of antagonism on nasal mannitol challenge in allergic
glimepiride and gliclazide in metformin- treated patients rhinitis: D.K.C. Lee, K. Haggart, G.P. Currie, S.D. Anderson
with Type 2 diabetes: a double-blind, crossover study: & B,J. Lipworth
P. Dhindsa, K.R. Davis & R. Donnelly
Penetration of piperacillin and tazobactam into 643 Erratum
pneumonic human lung tissue measured by in vivo
microdialysis: E Tomaselli, P. Dittrich, A. Maier, M. Woltsche, 644 Reviewers list
ly Matzi, J. Pinter, S. Nuhsbaumer, H. Pinter,J . Smelle &
EM. Smolle-Jiittne 646 Indices for Volume 55

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