British Journal of Clinical Pharmacology 1996: Vol 42 Table of Contents

5 Pages·1996·1.9 MB·English

Contents
Volume 42, Number 1, July 1996
Proceedings of the Festschrift in honour of Professor Dissecting the function of P450: A. R. Boobis,
Sir Colin Dollery R. J. Edwards, D. A. Adams & D. S. Davies
Heterocyclic amines: evaluation of their role in diet
Preface: D. S. Davies associated with human cancer: N. J. Gooderham,
Pathophysiology of asthma: P. J. Barnes S. Murray, A. M. Lynch, R. J. Edwards,
The asthma death problem revisited: R. W. Fuller M. Yadollahi-Farsani, C. Bratt, K. J. Rich, K. Zhao,
8-Epi PGF,,: specific analysis of an isoeicosanoid as B. P. Murray, S. Bhadresa, S. J. Crosbie,
an index of oxidant stress in vivo: N. Delanty, A. R. Boobis & D. S. Davies
M. Reilly, D. Pratico, D. J. Fitzgerald, J. A. Lawson A possible role for mono(ADP-ribosyl) transferase
& G. A. Fitzgerald in the signalling pathway mediating neutrophil
The causes of essential hypertension: M. J. Brown chemotaxis: J. R. Allport, L. E. Donnelly,
The treatment of hypertension: J. Chalmers P. Kefalas, G. Lo, A. Nunn, M. Yadollahi-Farsani,
New therapeutic agents for hypertension: J. L. Reid N. B. Rendell, S. Murray, G. W. Taylor &
Transgenic mouse models in carcinogenesis: J. MacDermot
interaction of c-myc with transforming growth factor Hypertensive cardiac hypertrophy — is genetic
a and hepatocyte growth factor in variance the missing link?: D. J. R. Nunez,
hepatocarcinogenesis: S. S. Thorgeirsson & C. P. Clifford, S. Al-Mahdawi & D. Dutka
E. Santoni-Rugiu Excursions in biomedical mass spectrometry:
A clinical pharmacologist’s view of drug toxicity: G. W. Taylor, L. E. Donnelly, S. Murray &
A. Breckenridge N. B. Rendell
The clinical pharmacologist in drug regulation: a The regulation of pulmonary vascular tone:
European perspective: M. D. Rawlins M. R. Wilkins, L. Zhao & R. Al-Tubuly
Clinical pharmacologists and drug regulation — future The clinical pharmacologist in drug discovery and
perspective in Japan: K. Hirokawa development: P. Lewis
The clinical pharmacologist in drug regulation: the Clinical pharmacology: future prospects for the
US perspective: R. J. Temple discipline: C. Dollery
Volume 42, Number 2, August 1996
Editorial Cholesterol lowering therapy inhibits the low-flow
Multi-centre trials: U-turns by bandwagons and the mediated vasoconstriction of the brachial artery in
patient left by the wayside: S. M. Dobbs, R. J. Dobbs hypercholesterolaemic subjects: J. L. Megnien,
& A. Charlett A. Simon, A. Andriani, P. Segond, S. Jeannin &
J. Levenson
Papers Combination of methotrexate and sulphasalazine in
Disposition of diazepam in young and elderly patients with rheumatoid arthritis: pharmacokinetic
subjects after acute and chronic dosing: R. J. Herman analysis and relationship to clinical response:
& G. R. Wilkinson C. J. Haagsma, F. G. M. Russel, T. B. Vree,
Diazepam-omeprazole inhibition interaction: an P.L. C. M. Riel& L. B. A. Van de Putte
in vitro investigation using human liver microsomes: Pharmacokinetics of bismuth and ranitidine following
K. Zomorodi & J. B. Houston single doses of ranitidine bismuth citrate:
The influence of renal function on the K. M. Koch, J. M. Davis, A. E. Gooding &
pharmacokinetics of unchanged and acyl- Y. Yin
glucuroconjugated ketoprofen enantiomers after 50 Pharmacokinetics of bismuth and ranitidine following
and 100 mg racemic ketoprofen: K. J. Skeith, multiple doses of ranitidine bismuth citrate:
M. Dasgupta, R. Lange & F. Jamali K. M. Koch, B. M. Kerr, A. E. Gooding & I. M. Davis
Pharmacodynamics and pharmacokinetics of BAY x A cohort study of the ocular safety of anti-ulcer
7195 aerosol, a new and selective receptor antagonist drugs: L. A. Garcia Rodriguez, S. Mannino,
of cysteinyl-leukotrienes, in normal volunteers: M-A. Wallander & B. Lindblom
G. Wensing, R. Heinig & J. Kuhlmann (-)-Timolol is a more potent antagonist of the
A study of 5 day fractionated ifosfamide positive inotropic effects of (—)-adrenaline than of
pharmacokinetics in consecutive treatment cycles: those of (—)-noradrenaline in human atrium:
L. L. Lewis T. Wang, A. J. Kaumann & M. J. Brown
The acute cardiovascular actions of intravenous Atovaquone has no effect on the pharmacokinetics of
thyrotrophin releasing hormone (TRH) in man are phenytoin in healthy male volunteers: J. D. Davis,
mediated by non-catecholamine mechanisms: R. Dixon, A. Z. Khan, S. Toon, P. E. Rolan &
P-M. Bouloux, S. Corsello, M. Besser & A. Grossman J. Posner
Lack of pharmacokinetic interaction of pantoprazole
Short reports
with diazepam in man: R. Gugler, M. Hartmann,
Calcium supplementation and ototoxicity in patients
J. Rudi, I. Brod, R. Huber, V. W. Steinijans,
receiving cisplatin: J. J. Grau, J. Estapé, M. A. Cuchi,
H. Bliesath, W. Wurst & U. Klotz
J. L. Firvida, J. L. Blanch & C. Ascaso
Patient awareness of the adverse effects of non-
Effect of locally applied prazosin on the kinetics of
steroidal anti-inflammatory drugs (NSAIDs):
the pupillary light reflex: S-A. Mortlock,
H. A. Wynne & A. Long
R. W. Langley, C. M. Bradshaw & E. Szabadi
The effects of reboxetine and amitriptyline, with and Letter to the Editors
without alcohol on cognitive function and Lung bioavailability of chlorofluorocarbon free, dry
psychomotor performance: J. S. Kerr, J. Powell & powder and chloroflurocarbon containing
I. Hindmarch formulations of salbutamol: H. Chrystyn:
Clonidine and or adrenaline decrease lignocaine B. J. Lipworth & D. J. Clark
plasma peak concentration after epidural injection: Proceedings of the British Pharmacological Society
J. X. Mazoit, D. Benhamou, Y. Veillette & K. Samii (The University of Leicester, 17-19 April 1996)
Volume 42, Number 3, September 1996
Reviews M. Audran, F. Bressolle, R. Gareau, A. Duvallet &
Estimating impossible curves using NONMEM: J.-L. Chanal
R. C. Schoemaker & A. F. Cohen y-L-glutamyl-5-hydroxy-L-tryptophan, but not y-L-
Clinical pharmacology of B3-adrenoceptors: glutamyl-L-tryptophan, causes sodium retention in
B. J. Lipworth normal man: T. C. Li Kam Wa, S. Freestone,
R. R. Samson, N. R. Johnson & M. R. Lee
Suppression of vagus-mediated pancreatic
Papers
polypeptide release by the p-opiate receptor agonist
The effect of age on the pharmacokinetics of the
loperamide in man: R. L. Riepl, B. Reichardt,
opioid antagonist nalmefene: R. F. Frye,
C. J. Auernhammer, G. Beier, J. Schopohl,
G. R. Matzke, N. S. Jallad, J. A. Wilhelm &
G. K. Stalla & P. Lehnert
G. B. Bikhazi
Pharmacokinetics, pharmacodynamics, long-term
A randomized, double-blind, placebo-controlled trial
efficacy and safety of oral 1-deamino-8-D-arginine
controlling pethidine to metamizol for treatment of
vasopressin in adult patients with central diabetes
post-anaesthetic shivering: A. Monsd, J. Riudeubas,
insipidus: K. S. L. Lam, M. S. Wat, K. L. Choi,
F. Barbal, J-R. Laporte & A. P. M. Arnau
T. P. Ip, R. W. C. Pang & C. R. Kumana
Taste loss to terbinafine: a case-control study of
potential risk factors: B. H. Ch. Stricker, Short reports
M. M. Van Riemsdijk, M. C. J. M. Sturkenboom & Expression of CYP3A4, CYP3A5 and CYP3A7 in
J. P. Ottervanger human duodenal tissue: K. T. Kivisté, G. Bookjans,
A prospective study of adverse drug reactions as a M. F. Fromm, E.-U. Griese, P. Miinzel &
cause of admission to a paediatric hospital: H. K. Kroemer
I. Martinez-Mir, M. Garcia-Lopez, V. Palop, Variable contribution of CYP2D6 to the N-
J. M. Ferrer, L. Estafi, E. Rubio & F. J. Morales- dealkylation of S-(-)-propranolol by human liver
Olivas microsomes: K. Rowland, S. Wynne Ellis,
Single-dose pharmacokinetics of ampicillin and M. S. Lennard & G. T. Tucker
tobramycin administered by hyperdermoclysis in Influence of liver cirrhosis on sertraline
young and older healthy volunteers: N. Champoux, pharmacokinetics: J-L. Démolis, P. Angebaud,
P. Du Souich, M. Ravaoarinoro, D. Phaneuf, J-D. Grangé, P. Coates, C. Funck-Brentano &
J. Latour & J. R. Cusson P. Jaillon
Lipid-lowering drugs and mitochondrial function:
effects of HMG-CoA reductase inhibitors on serum Letters to the Editors
ubiquinone and blood lactate/pyruvate ratio: G. De Drug-induced QT interval prolongation:
Pinieux, P. Chariot, M. Ammi-Said, F. Louarn, S. H. L. Thomas: M. Thomas, J. G. Maconochie &
J. L. Lejonc, A. Astier, B. Jacotot & R. Gherardi E. Fletcher
Racial differences in propranolol enantiomer kinetics Cross over trials: P. R. Jackson & W. W. Yeo:
following simultaneous i.v. and oral administration: T. J. M. Cleophas
K. M. Sowinski, J. J. Lima, B. S. Burlew, Parenteral administration of 8-methoxypsoralen:
J. D. Massie & J. A. Johnson R. M. Knobler & F. Trautinger: V. Billard &
The effect of fluconazole and ketoconazole on the S. L. Shafer
metabolism of sulphamethoxazole: H. J. Gill,
Book review
J. L. Maggs, S. Madden, M. Pirmohamed &
Handbook of Drugs for Tropical Parasitic Infections
B. K. Park
(2nd edn) by Y. A. Abdi, L. L. Gustafsson,
Pharmacokinetics and pharmacodynamics of
O. Ericsson & U. Hellgren: 1. G. Edwards
recombinant human erythropoietin in athletes. Blood
sampling and doping control: A. Souillard, Erratum
Volume 42, Number 4, October 1996
Review M. J. Ouwersloot-Van der Meij, H. G. J. Hoedemaker
Drug toxicity and surveillance in children: & A. F. Cohen
I. Choonara, A. Gill & A. Nunn Absence of effects of prolonged simvastatin therapy
on nocturnal sleep in a larger randomized placebo-
Opinion
controlled study: A. C. Keech, J. M. Armitage,
Mefloquine: the benefits outweigh the risks:
K. R. Wallendszus, A. Lawson, A. J. Hauer,
P. Winstanley
S. E. Parish & R. Collins
Papers Double-blind comparative study of the
Neurological, cardiovascular and metabolic effects of antidepressant, unwanted and cardiac effects of
mefloquine in healthy volunteers: a double-blind, minaprine and amitriptyline: J. G. Edwards,
placebo-controlled trial: T. M. E. Davis, T. G. Dinan, D. G. Waller & S. G. Greentree
L. G. Dembo, S. A. Kaye-Eddie, B. J. Hewitt,
R. G. Hislop & K. T. Batty Short reports
Adverse drug reactions in a hospital general medical Assessment of changes in liver blood flow after food
unit meriting notification to the Committee on Safety intake—comparison of ICG clearance and echo-
of Medicines: C. C. Smith, P. M. Bennett, Doppler: J. Burggraaf, H. C. Schoemaker &
H. M. Pearce, P. I. Harrison, D. J. M. Reynolds, A. F. Cohen
J. K. Aronson & D. G. Grahame-Smith Miglitol (Bay m 1099) has no extraintestinal effects
5-HT,p receptor agonists and human coronary artery on glucose control in healthy volunteers:
reactivity in vitro: crossover comparisons of 5-HT J. P. J. E. Sels, J. J. P. Nauta, P. P. C. A. Menheere,
and sumatriptan with rizatriptan and L-741,519: B. H. R. Wolffenbuttel & A. C. Nieuwenhuijzen
J. Longmore, C. M. Boulanger, B. Desta, R. G. Hill, Kruseman
W. N. Schofield& A. A. Taylor a-adrenoceptor blocking drugs and female urinary
Pharmacokinetics of trapidil, an antagonist of incontinence: prevalence and reversibility:
platelet derived growth factor, in healthy subjects and H. J. Marshall & D. G. Beevers
in patients with liver cirrhosis: S. Harder, Food intake and dosage level, but not tablet vs
P. A. Thiirmann, A. Hellstern & Anna Benjaminov solution dosage form, affect the absorption of
Captopril has no significant scavenging antioxidant metformin HCl in man: N. C. Sambol, L. G. Brookes,
activity in human plasma in vitro or in vivo: J. Chiang, A. M. Goodman, E. T. Lin, C. Y. Liu &
D. Lapenna, S. De Gioia, G. Ciofani, F. Daniele & L. Z. Benet
F. Cuccurullo Lack of pharmacokinetic interaction between
Inhibition of ex vivo neutrophil activation by oral butorphanol nasal spray and cimetidine: W. C. Shyu
LY293111, a novel leukotriene B, receptor & R. H. Barbhaiya
antagonist: P. Marder, S. M. Spaethe, L. L. Froelich, In vivo inhibition of CYP2C19 but not CYP2D6 by
B. J. Cerimele, B. H. Petersen, T. Tanner & fluvoxamine: Z-H. Xu, H-G. Xie & H-H. Zhou
R. A. Lucas Effects of frusemide on the urinary excretion of
Effect of fluconazole dose on the extent of dopamine and 5-hydroxytryptamine in normal man:
fluconazole-triazolam interaction: A. Varhe, T. C. Li Kam Wa, S. Freestone, J. L. McCrindle,
K. T. Olkkola & P. J. Neuvonen R. R. Samson, N. R. Johnston & M. R. Lee
The elimination of diazepam in Chinese subjects is Mercaptopurine in childhood leukaemia: the effects
dependent on the mephenytoin oxidation phenotype: of dose escalation on thioguanine nucleotide
J. Wan, H. Xia, N. He, Y-Q. Lu & H-H. Zhou metabolites: L. Lennard, J. Welch & J. S. Lilleyman
Self-medication of a single headache episode with
ketoprofen, ibuprofen or placebo, home-monitored Letter to the Editor
with an electronic patient diary: J. M. A. Van Gerven, CYP2E1 activity is not altered by influenza
R. C. Schoemaker, L-D. Jacobs, A. Reints, vaccination: R. B. Kim & G. R. Wilkinson
Volume 42, Number 5, November 1996
Review Medicine taking in Southampton: a second look:
The new generation of antiepileptic drugs: advantages M. J. Sullivan & C. F. George
and disadvantages: E. Perucca Single and multiple dose pharmacokinetics of
nefazodone in subjects classified as extensive and
Meeting report poor metabolizers of dextromethorphan:
Symposium on Pharmacogenetics R. H. Barbhaiya, A. B. Buch & D. S. Greene
Pharmacokinetics and pharmacodynamics of
Papers (+)-sotalol in healthy male volunteers: M. Kimura,
Drug and Therapeutics Committees in Australia: K. Umemura, Y. Ikeda, K. Kosuge, A. Mizuno,
expected and actual performance: L. M. Weekes & H. Nakanomyo, K. Ohashi & M. Nakashima
C. Brooks Population pharmacokinetics of proguanil in patients
Postmarketing surveillance of oral terbinafine in the with acute P. falciparum malaria after combined
UK: report of a large cohort study: D. P. O'Sullivan, therapy with atovaquone: Z. Hussein, C. J. Eaves,
C. A. Needham, A. Bangs, K. Atkin & F. D. Kendall D. B. Hutchinson & C. J. Canfield
Comparative bioavailability of oral, rectal, and Short reports
intramuscular artemether in healthy subjects: use of Effect of intravenous magnesium sulphate on airway
simultaneous measurement by high performance calibre and airway reactivity to histamine in
liquid chromatography and bioassay: asthmatic subjects: J. M. Hill & J. Britton
P. Teja-Isavadharm, F. Nosten, D. E. Kyle, Lack of gender effect on ciprofloxacin
C. Luxemburger, F. Ter Kuile, J. O. Peggins, pharmacokinetics in humans: K. Gallicano & J. Sahai
T. G. Brewer & N. J. White A single sample saliva test to determine acetylator
The implications of non-linear red blood cell phenotype: A. D. Hutchings & P. A. Routledge
partitioning for the pharmacokinetics and Erythrocyte thiopurine methyltransferase activity in a
pharmacodynamics of the nucleoside transport Korean population: I. J. Jang, S. G. Shin, K. H. Lee,
inhibitor draflazine: E. Snoeck, P. Jacqmin, D. S. Yim, M. S. Lee, H. H. Koo, H. K. Kim &
A. Van Peer, M. Danhof, K. Ver Donck, H. Van Belle, D. R. Sohn
R. Woestenborghs, R. Crabbé, R. Van Gool, Diltiazem does not always increase blood cyclosporin
A. Dupont & J. Heykants concentration: T. E. Jones & R. G. Morris
Pharmacokinetics and haemodynamic effects of the
angiotensin converting enzyme inhibitor cilazapril in
Letter to the Editor
hypertensive patients with normal and impaired renal
Effect of food on the comparative pharmacokinetics
function: H. J. Kloke, R. J. Ambros,
of modified-release morphine tablet formulations,
H. W. Van Hamersvelt, J. F. M. Wetzels,
Oramorph SR and MST Continus: A. J. Miller &
R. A. P. Koene & F. T. M. Huysmans
K. J. Smith: J. Drake, C. E. Horth & F. E. Crawford
Effects of lamotrigine on EEG paroxysmal
abnormalities and background activity: a
computerized analysis: M. G. Marciani, F. Spanedda, Proceedings
M. A. Bassetti, M. Maschio, G. L. Gigli, D. Mattia & Proceedings of the British Pharmacological Society
G. Bernardi (10-12 July 1996, University of Bath)
Volume 42, Number 6, December 1996
Editorial Characterization and validation of a pharmacokinetic
Thrombolysis for stroke: pushed out of the window?: model for controlled-release oxycodone:
K. W. Muir J. W. Mandema, R. F. Kaiko, B. Oshlack, R. F. Reder
& D. R. Stanski
Reviews A comparison of the post-marketing safety of four
Genes, disease and medicine: C. W. Dykes selective serotonin re-uptake inhibitors including the
Pharmacokinetics of inhaled drugs: B. J. Lipworth investigation of symptoms occurring on withdrawal:
J. S. Price, P. C. Waller, S. M. Wood &
A. V. P. MacKay
Papers Clinical drug monitoring by microdialysis:
Involvement of CYP2D6 but not CYP2C19 in application to levodopa therapy in Parkinson’s
nicergoline metabolism in humans: Y. Béttiger, disease: M. T. O’Connell, F. Tison, N. P. Quinn &
P. Dostert, M. Strolin Benedetti, M. Bani, P. N. Patsalos
F. Fiorentini, M. Casati, I. Poggesti, C. Alm, G. Alvan
Short reports
& L. Bertilsson
Proguanil metabolism in relation to S-mephenytoin
A novel mutant variant of the CYP2D6 gene
oxidation in a Turkish population: N. E. Basci,
(CYP2D6*17) common in a black African
A. Bozkurt, S. Kortunay, A. Isimer, A. Sayal &
population: association with diminished debrisoquine
S. O. Kayaalp
hydroxylase activity: C. Masimirembwa, I. Persson,
Limited value of the urinary phenytoin metabolic
L. Bertilsson, J. Hasler & M. Ingelman-Sundber-
ratio for the assessment of cytochrome P4502C9
Effect of captopril on prostacyclin and nitric oxide
activity in vivo: W. Tassaneeyakul, D. J. Birkett,
formation in healthy human subjects: Interaction
M. C. Pass & J. O. Miners
with low dose acetylsalicylic acid: R. H. Béger,
Pharmacokinetics of the individual enantiomers of
S. M. Bode-Béger, P. Kramme, D. Tsikas,
vigabatrin in neonates with uncontrolled seizures:
F-M. Gutzki & J. C. Frélich
F. Vauzelle-Kervroédan, E. Rey, G. Pons, Ph. d’Athis,
Erythropoietin production in healthy volunteers
C. Chiron, O. Dulac, C. Dumas & G. Olive
subjected to controlled haemorrhage: evidence
Effects of picotamide, an antiplatelet agent, on
against a major role for adenosine: C. H. Gleiter,
cardiovascular events in 438 claudicant patients with
S. Freudenthaler, U. Delabar, K. U. Eckardt,
diabetes: a retrospective analysis of the ADEP study:
B. Miihlbauer, U. Gundert-Remy & H. Osswald
M. Milani, A. Longoni & M. Maderna
A method for simultaneous determination of plasma
and erythrocyte antioxidant status. Evaluation of the
Letter to the Editors
antioxidant activity of vitamin E in healthy
Improved tolerability of ritonavir derived from
volunteers: A. Abella, C. Messaoudi, D. Laurent,
pharmacokinetic principles: C. Merry, M. Barry,
D. Marot, J. Chalas, J. Breux, C. Claise &
S. Gibbons, F. Mulcahy & D. Back
A. Lindenbaum
Effect of food on the absorption of frusemide and List of Referees
bumetanide in man: J. L. McCrindle,
T. C. Li Kam Wa, W. Barron & L. F. Prescott Indexes to Volume 42
oy