Brain: Fetal and Infant

359 Pages·1977·8.488 MB·English

by  Paul Mandel M.D., Ph.D., Henry Dreyfus Ph.D., Suzanne Harth Ph.D. (auth.), Samuel R. Berenberg M.D. (eds.)

BRAIN
BRAIN
FETAL AND INFANT
Curren! Research on Normal and Abnormal Development
edited by
SAMUEL R. BERENBERG, M.D.
1977
MARTINUS NIJHOFF MEDICAL DIVISION -THE HAGUE
This volume is based on the proceedings of a conference held under the joint auspice,
of the Josiah Macy jr. Foundation and the International Children's Center in Paris,
December 14-16, 1976.
The conference was dedicated to the memory of Dr. Nathalie Masse, for many years
Director of Teaching at the International Children's Center.
ISBN 978-94-011-8221-8 ISBN 978-94-011-8884-5 (eBook)
DOl 10.1007/978-94-011-8884-5
© 1977 by Martinus Nijhoff. The Hague. Netherlands
Softcover reprint of the hardcover 1st edition 1977
No part of this book may be reproduced in any form. by print. photoprint.
microfilm or any other means. without written permission from the publisher.
HOMMAGE TO DR. NATHALIE P. MASSE
During the conference, the Macy Foundation presented a plaque as an en
during memorial to the contributions of Nathalie Masse, and the following
comments were made at the ceremony:
"Nathalie Masse was Professor of Pediatrics to the world. More than a
thousand pediatricians from scores of countries attended her classes in
Europe, Latin America, Asia, and Africa.
"Nathalie's many travels were made easier by her assurance that she would
return to a loving husband, and himself a distinguished physician, Paul
Masse.
"Her professional life was intertwined with that of her patron and France's
most distinguished medical statesman, Professor Robert Debre.
"She loved to recall leading the 'force de frappe', which, under the orders of
Robert Debre, converted an abandoned chateau in the Bois de Boulogne into
the splendid Centre International de L'Enfance that we meet in today.
"Nath-alie Masse was lovely in her features; she was endearing and loved
people; and she was a remarkably versatile scholar.
"She died in August, 1975.
"We mourn her loss, but today we wish to express our thanks and to rejoice
for the children of the world who benefitted from the life of Nathalie Masse."
JOHN Z. BOWERS
CONTENTS
Hommage to DR. NATHALIE P. MASSE. V
Participants XI
Abbreviations. XIII
1. PAUL MANDEL. HENRI DREYFUS. SUZANNE HARTH. LOUIS FREYSZ.
and PAUL-FRANCIS URBAN. Lipids of chick retina during
ontogenesis
2. ROGER N. ROSENBERG.Protein synthesis by differentiating neuro
blasts and glioblasts in cell culture: a model system for analysis
of genetic neurologic disease. 22
3. TH. RABINOWICZ. G. LEUBA. and D. HEUMANN. Morphologic
maturation of the brain: a quantitative study 28
4. DOMINICK P. PURPURA. Factors contributing to abnormal neu-
ronal development in the cerebral cortex of the human infant. 54
5. HEINZ F. R. PRECHTL. Assessment and significance of behavioural
states 79
6. JEAN-LoUIS VALATX. Sleep behavior: genetic regulation. 91
7. MICHEL IMBERT. Developmental plasticity in the visual cortex 99
8. HENRY HECAEN. Language representation and brain development 112
9. ARTHUR L. PRENSKY and LAURA HILLMAN. Zinc and the develop-
ing nervous system: toxic effects of zinc on the central nervouS
system of the preweanling rabbit 124
VII I CONTENTS
10. JACQUES LEGRAND. Morphologic and biochemical effects of hor
mones on the developing nervous system in mammals 137
II. ELLSWORTH C. ALVORD. JR. and S. MARK SUM I. Effects of drugs.
narcotics and toxins on the chemical maturation of the infant
brain 165
12. LOUIS B. SOKOLOFF. Toxic effects of elevated oxygen tension on
brain maturation 178
13. BARRY G.W. ARNASON. Nerve growth factor 184
14. RICHARD T. JOHNSON. Viral infections and brain development 213
15. ELLSWORTH C. ALVORD. JR. and CHENG-MEl SHAW. Infectious
and immunologic diseases affecting the developing nervous
system 224
16. M. HAMON and S. BOURGOIN. Biochemical aspects of the matura
tion of serotoninergic neurons in the rat brain . 239
17. ROBERT Y. MOORE. The development of central catecholamine
neuron systems: some implications for disease . 262
18. FRED PLUM and C. G. WASTERLAIN. Developmental retardation
in rat brain after perinatal seizures 266
19. CLAUDE G. WASTERLAIN and THOMAS E. DUFFY. Pathophysiologic
basis for the selective vulnerability of the immature rat brain to
seizures. 274
20. JEAN AICARDI. Post-natal seizures clinical effects. 295
21. MADGE E. SCHEIBEL and ARNOLD B. SCHEIBEL. Specific postnatal
threats to brain development: dendritic changes 302
22. THOMAS E. DUFFY and ROBERT C. VANNUCCI. Metabolic aspects of
cerebral anoxia-asphyxia in the fetus and newborn 316
CONTENTS IX
23. LOUIS B. SOKOLOFF. Postnatal maturation of the local cerebral
circulation. 324
24. BRUNO E. WILL, Methods for promoting functional recovery fol
lowing brain damage 330
Index. 345
PARTICIPANTS
Jean Aicardi, M.D., Maitre de Recherche a nnstitut National de Ii Sante et de la Recherche
Medicale, H6pital St Vincent de Paul, 74 Avenue Denfert Rochereau, 75674 Paris Cede x 14,
France
Ellsworth C. Alvord, Jr., M.D., Professor of Pathology, Neuropathology Laboratory (RJ-05)
University of Washington School of Medicine, Seattle, Washington 98195, USA [co-author
for chapter 15: Cheng-Mei Shaw, M.D., Professor of Pathology, at above address]
Barry G.W. Arnason, M.D., Professor and Chairman, Department of Neurology, The Pritzker
School of Medicine, University of Chicago, Chicago, Illinois, USA
Thomas E. Duffy, Ph.D., Associate Professor of Biochemistry in Neurology, Departments of
Neurology and Biochemistry, Cornell University Medical College, 525 East 68th Street, New
York, N.Y. 10021, USA [co-author for chapter 22: Robert C. Vannucci, M.D., Assistant
Professor of Pediatric Neurology, Department of Pediatrics, Milton S. Hershey Medical
Center, The Pennsylvania State University, Hershey, Pennsylvania, USA]
Edith Farkas, M.D., Service du Professeur Thieffry, H6pital St Vincent de Paul, 74 Avenue
Denfert Rochereau, 75674 Paris Cedex 14, France
Michel Hamon, M.D., Groupe de Neuropharmacologie Biochimique, INSERM U.114,
Laboratoire de Neurophysiologie, College de France, II Place Marcelin Berthelot, 75231
Paris Cedex 05, France [co-author for chapter 16: S. Bourgoin, Ph.D., at above address]
a
Henry Hecaen, M.D., Directeur d'Etudes I'E.H.E.S.S., Centre de Recherches de l'INSERM
sur les Maladies du Systeme Nerveux Central, 2 ter rue de'Alesia, 75014 Paris, France
Michellmbert, M.D., Laboratoire de Neurophysiologie, College de France, II Place Marcelin
Berthelot, 75231 Paris Cedex 05, France
Richard T. Johnson, M.D., Eisenhower Professor of Neurology and Professor of Microbiology,
School of Medicine, The Johns Hopkins University, 601 North Broadway, Baltimore,
Maryland 21205, USA
A. Jost, M.D., Professeur, Laboratoire de Physiologie du Developpement du College de France
et de l'Universite Pierre et Marie Curie, 9 Quai St Bernard, 75230 Paris Cedex 05, France
Jacques Legrand, M.D., Professeur, Laboratoire de Physiologie Comparee, Universite des
Sciences et Techniques du Languedoc, Place Eugene Bataillon, 34060 Montpe:Iier Cedex,
France
Paul Mandel, M.D., Professor of Biochemistry at the Medical School, Centre de Neurochimie,
II rue Humann, 67085 Strasbourg Cedex, France [co-authors du CNRS, Faculte de Medicine
a
for chapter I: Henry Dreyfus, Ph.D., Attache de Recherche I'INSERM; Suzanne Harth,
X I I PARTICIPANTS
Ph.D .. Charge de Recherche au CNRS: Louis Freysz. Ph.D .. Charge de Recherche au CNRS:
Paul-Francis Crban. Ph.D .. Charge de Recherche au CNRS - all at above address]
Robert Y. Moore. M.D .. Professor. Department of Neurosciences. School of Medicine.
University of California at San Diego. La Jolla. Calif. 92093. USA
Fred Plum. M.D .. Ann Parrish Titzell Professor of Neurology. Department of Neurology. The
New York Hospital-Cornell Medical Center. 525 East 68th Street. New York. N.Y. 10021.
USA
Heinz F.R. Prechtl. M.D .. Director. Department of Developmental Neurology. University
Hospital. Oostersingel 59. Groningen. The Netherlands
Arthur L. Prensky. M.D .. The Allen P. and Josephine B. Green Professor of Pediatric
Neurology. Mallinckrodt Department of Pediatrics and Department of Neurology.
Washington University School of Medicine. 500 S. Kingshighway Blvd. St. Louis. Missouri
63110. USA; Director of the Division of Pediatric Neurology. SI. Louis Children's Hospital.
SI. Louis. Missouri. USA [co-author for chapter 9: Laura Hillman. M.D .. Assistant Professor
of Pediatrics. Edward Mallinckrodt Department of Pediatrics. Washington University School
of Medicine. SI. Louis. Missouri]
Dominick P. Purpura. M.D .. Professor and Chairman. Department of Neuroscience. Albert
Einstein College of Medicine. Bronx. N.Y . .l0461. USA
Th. Rabinowicz. M.D .. Assoc. Professor. Head. Division of Neuropathology. I Ch. des Falaises.
Lausanne. Switzerland [co-authors for chapter 3: G. Leuba; D. Heumann]
Geoffrey Raisman. M.D .. National Institute for Medical Research. The Ridgeway. Mill Hill.
London NW7 IAA. United Kingdom
Roger N. Rosenberg. M.D .. Professor of Neurology and Physiology. Chairman. Department of
Neurology. Southwestern Medical School. Health Science Center at Dallas. The University of
Texas. 5323 Harry Hines Boulevard. Dallas. Texas 75235. USA
Arnold Scheibel. M.D. and Madge Scheibel. Departments of Anatomy and Psychiatry and Brain
Research Institute. L'CLA Center for the Health Sciences School of Medicine. Los Angeles.
California 90024. USA
Louis Sokoloff. M.D .. Chief. Laboratory of Cerebral Metabolism; National Institute of
Mental Health; U.S. Department of Health. Education. and Welfare; Public Health Service;
Alcohol. Drug Abuse. and Mental Health Adm. Bldg 36. Room IA-27. 900 Rockville Pike.
Bethesda. Maryland 20014. USA
Constantino Sotelo M.D .. Laboratoire de Neuromorphologie. Groupe U .106. INSERM. 123
Boulevard de Port-Royal. 75014 Paris. France
Jean-Louis Valatx. M.D .. Charge de Recherches. INSERM U. Departement de Medicine
Experimentale, Universite Claude Bernard, 8 Avenue Rockefeller, 69373 Lyon, France
Claude G. Wasterlain. M.D .. Associate Professor of Neurology. University of California. Los
Angeles. Calif.: Chief. Neurology Division, School of Medicine. San Fernando Valley Medical
Program. Veterans Administration Hospital. Sepulveda. California 91343. USA
Bruno E. Will. M.D .. Laboratoire de Psychophysiologie. Universite Louis Pasteur. 7 rue de
I'Universite. 67000 Strasbourg. France [co-author for chapter 19: Thomas E. Duffy. Ph.D ..
Associate Professor of Neurology and Biochemistry. Cornell University Medical College.
New York. New York]
ABBREVIA TIONS
ATP Adenosine Triphosphate
B2cAMP Dibutyryl Cyclic Adenosine Monophosphate
BudR Bromodeoxyuridine
CA. Chronologic age
Cer Cerebroside
CerSO, Sulpha tide. cerebroside sulphate
CGluT UDP-glucose: ceramide glucosyltransferase
CGluGalT UDP-galactose: glucosylceramide galactosyltransferase
CNS Central nervous system
CPT CDP-choline 1-2 diglyceride choline phosphotransferase
CST Cerebroside sulphotransferase
DNA Deoxyribonucleic acid
DNase I Deoxyribonuclease I
EEG Electroencephalogram
EPT CDP-ethanolamine 1-2 diglyceride ethanolamine phosphotransferase
ERG Electroretinogram
Ganglioside nomenclature of Svennerholm (1963)
GM3 Monosialosyl-Iactosylceramide
GM2 M onosialosyl-N -triglycosylceramide
GMI M onosialosyl-N -tetraglycosylceramide
GD3 Disialosyl-Iactosylceramide
GDla Disialosyl-N-tetraglycosylceramide
GDlb Disialosyl-N-tetraglycosylceramide
GTI Trisialosyl-N-tetraglycosylceramide