Brain Edema XIII

461 Pages·2006·12.342 MB·English

by  T. Kawamata, Y. Katayama (auth.), Julian T. Hoff, Richard F. Keep, Guohua Xi, Ya Hua (eds.)

W
Acta Neurochirurgica
Supplements
Editor: H.-J. Steiger
Brain Edema XIII
Edited by
J.T. Hoff, R.F. Keep, G. Xi, and Y. Hua (eds.)
Acta Neurochirurgica
Supplement 96
SpringerWienNewYork
JulianT.Ho¤
RichardF.Keep
GuohuaXi
YaHua
UniversityofMichigan,DepartmentofNeurosurgery,AnnArbor,Michigan,USA
Thisworkissubjecttocopyright.
Allrightsarereserved,whetherthewholeorpartofthematerialisconcerned,specificallythoseoftranslation,reprinting,re-useof
illustrations,broadcasting,reproductionbyphotocopyingmachinesorsimilarmeans,andstorageindatabanks.
ProductLiability:Thepublishercangivenoguaranteeforalltheinformationcontainedinthisbook.Thisalsoreferstothatondrugdosage
andapplicationthereof.Ineachindividualcasetherespectiveusermustchecktheaccuracyoftheinformationgivenbyconsultingother
pharmaceuticalliterature.Theuseofregisterednames,trademarks,etc.inthispublicationdoesnotimply,evenintheabsenceofspecific
statement,thatsuchnamesareexemptfromtherelevantprotectivelawsandregulationsandthereforefreeforgeneraluse.
62006Springer-Verlag/Wien
PrintedinAustria
SpringerWienNewYorkisapartofSpringerScienceþBusinessMedia
springeronline.com
Typesetting:AscoTypesetters,HongKong
PrintingandBinding:DruckereiTheissGmbH,St.Stefan,Austria,www.theiss.at
Printedonacid-freeandchlorine-freebleachedpaper
SPIN:11594406
LibraryofCongressControlNumber:2005937333
WithpartlycolouredFigures
ISSN0065-1419
ISBN-10 3-211-30712-5SpringerWienNewYork
ISBN-13 978-3-211-30712-0SpringerWienNewYork
Preface
TheXIIIInternationalSymposiumonBrainEdema intracerebralhemorrhage,includingtheprimaryevent
andTissueInjurywasheldJune1–3,2005,inAnnAr- andthesecondaryinjurythatfollows,promptedaone-
bor,Michigan,USA.Thisvolumeincludespaperspre- daysatelliteconferenceonthesubject.Theconference
sented at the symposium as well as papers that were was held immediately after the Brain Edema Sympo-
presentedatasatelliteIntracerebralHemorrhageCon- sium. Most participants in the Brain Edema Sympo-
ferenceonJune4,2005.Inkeepingwiththeoutstand- sium stayed an extra day to learn about the latest de-
ingXIISymposiumheldinHakone,Japanin2002,we velopments in intracerebral hemorrhage research,
chose to include brain tissue injury as well as brain includingongoingclinicaltrialsandbasicresearchin-
edema as the subject matter for this meeting. Brain vestigationfocusingprimarilyonthesecondaryevents
edema, in many respects, is a marker of underlying whichdevelopafterthehemorrhage.
pathological processes which include tissue injury There was considerable enthusiasm to continue the
frommanydiseases. Brain Edema Symposium series at the conclusion of
The scientific sessions included invited speakers, the thirteenth meeting. The Advisory Board chose
oral presentations, poster sessions, and panel discus- Warsaw,Polandasthenextsiteforthemeetingunder
sions. The meeting emphasized scientific excellence in the direction of Professor Zbigniew Czernicki and his
a congenial atmosphere focusing on both basic and colleagues. Symposium attendees look forward to a
clinicalscience. successfulmeetinginthatcityin2008.
Thesymposiumfeaturedbasicscienceresearchpre- The editors wish to thank Ms. Kathleen Donahoe,
sentations as well as clinical observations in a variety Ms. Holly Wagner, and the sta¤ of Springer-Verlag
of categories, including traumatic brain injury, cere- for the commitment and editorial skills necessary to
bral hemorrhage, cerebral ischemia, hydrocephalus, preparethisvolumeforpublication.
intracranialpressure,waterchannels,andblood-brain
barrier disruption. The recent increase of interest in JulianT.Ho¤,RichardKeep,GuohuaXi,andYaHua
Acknowledgments
The Editors would like to express their sincere J.R.Carhuapoma
thankstothosewhomadetheBrainEdemaXIIISym- D.F.Hanley
posium and the satellite Intracerebral Hemorrhage S.A.Mayer
Conference possible. Thanks are due especially to the A.D.Mendelow
International and Local Advisory Boards for both S.Nagao
meetings: R.J.Traystman
K.R.Wagner
M.Zuccarello
BrainEdemaXIII
LocalOrganizingCommittee
InternationalAdvisoryBoard
J.T.Ho¤(Chair)
A.Baethmann
W.G.Barsan
Z.Czernicki
R.F.Keep
U.Ito
L.B.Morgenstern
Y.Katayama
Y.Hua
T.Kuroiwa
G.Xi
A.Marmarou
A.D.Mendelow
The meeting would not have been possible without
thehardworkofKathleenDonahoeandHeidiZayan
LocalOrganizingCommittee asSecretariat,PamelaStatonandmembersofUniver-
sity of Michigan Conference Management Services,
J.T.Ho¤(Chair)
Drs. Yangdong He, Shuijiang Song, and Wenquan
R.F.Keep
Liu (Department of Neurosurgery, University of
Y.Hua
Michigan)fortheirexpertisewiththeaudio/visualpre-
G.Xi
sentations,andDrs.JohnCowanandJean-Christophe
Leveque(DepartmentofNeurosurgery,Universityof
IntracerebralHemorrhageConference Michigan) for design and maintenance of the Brain
Edema2005website.
WewouldalsoliketothanktheNationalInstitutes
InternationalAdvisoryBoard
ofHeathandNovoNordiskforprovidingeducational
J.Aronowski grantsinsupportofthemeeting.
K.J.Becker
Contents
HumanBrainInjury
Kawamata,T.,Katayama,Y.:
Surgicalmanagementofearlymassiveedemacausedbycerebralcontusioninheadtraumapatients...... 3
Chambers,I.R.,Barnes,J.,Piper,I.,Citerio,G.,Enblad,P.,Howells,T.,Kiening,K.,Mattern,J.,
Nilsson,P.,Ragauskas,A.,Sahuquillo,J.andYau,Y.H.fortheBrainITGroup:
BrainIT:atrans-nationalheadinjurymonitoringresearchnetwork........................................ 7
Timofeev,I.,Kirkpatrick,P.J.,Corteen,E.,Hiler,M.,Czosnyka,M.,Menon,D.K.,Pickard,J.D.,
Hutchinson,P.J.:
Decompressivecraniectomyintraumaticbraininjury:outcomefollowingprotocol-driventherapy....... 11
Hutchinson,P.J.,Corteen,E.,Czosnyka,M.,Mendelow,A.D.,Menon,D.K.,Mitchell,P.,Murray,G.,
Pickard,J.D.,Rickels,E.,Sahuquillo,J.,Servadei,F.,Teasdale,G.M.,Timofeev,I.,Unterberg,A.,
Kirkpatrick,P.J.:
Decompressivecraniectomyintraumaticbraininjury:therandomizedmulticenterRESCUEicpstudy
(www.RESCUEicp.com) ................................................................................... 17
Ng,S.C.P.,Poon,W.S.,Chan,M.T.V.:
Cerebralhemisphereasymmetryincerebrovascularregulationinventilatedtraumaticbraininjury....... 21
Marmarou,A.,Signoretti,S.,Aygok,G.,Fatouros,P.,Portella,G.:
Traumaticbrainedemaindi¤useandfocalinjury:cellularorvasogenic?.................................. 24
Beaumont,A.,Gennarelli,T.:
CTpredictionofcontusionevolutionafterclosedheadinjury:theroleofpericontusionaledema......... 30
Utagawa,A.,Sakurai,A.,Kinoshita,K.,Moriya,T.,Okuno,K.,Tanjoh,K.:
Organdysfunctionassessmentscoreforsevereheadinjurypatientsduringbrainhypothermia............ 33
Kinoshita,K.,Sakurai,A.,Utagawa,A.,Ebihara,T.,Furukawa,M.,Moriya,T.,Okuno,K.,
Yoshitake,A.,Noda,E.,Tanjoh,K.:
Importanceofcerebralperfusionpressuremanagementusingcerebrospinaldrainageinseveretraumatic
braininjury.................................................................................................. 37
Mori,T.,Katayama,Y.,Kawamata,T.:
Acutehemisphericswellingassociatedwiththinsubduralhematomas:pathophysiologyofrepetitivehead
injuryinsports.............................................................................................. 40
Kinoshita,K.,Utagawa,A.,Ebihara,T.,Furukawa,M.,Sakurai,A.,Noda,A.,Moriya,T.,Tanjoh,K.:
Rewarmingfollowingaccidentalhypothermiainpatientswithacutesubduralhematoma:casereport.... 44
X Contents
Furukawa,M.,Kinoshita,K.,Ebihara,T.,Sakurai,A.,Noda,A.,Kitahata,Y.,Utagawa,A.,Moriya,T.,
Okuno,K.,Tanjoh,K.:
Clinicalcharacteristicsofpostoperativecontralateralintracranialhematomaaftertraumaticbraininjury 48
HumanIntracranialHemorrhage
Compagnone,C.,Tagliaferri,F.,Fainardi,E.,Tanfani,A.,Pascarella,R.,Ravaldini,M.,Targa,L.,
Chieregato,A.:
Diagnosticimpactofthespectrumofischemiccerebralbloodflowthresholdsinsedatedsubarachnoid
hemorrhagepatients......................................................................................... 53
Dohi,K.,Jimbo,H.,Ikeda,Y.,Fujita,S.,Ohtaki,H.,Shioda,S.,Abe,T.,Aruga,T.:
Pharmacologicalbraincoolingwithindomethacininacutehemorrhagicstroke:antiinflammatory
cytokinesandantioxidativee¤ects.......................................................................... 57
Prasad,K.S.M.,Gregson,B.A.,Bhattathiri,P.S.,Mitchell,P.,Mendelow,A.D.:
ThesignificanceofcrossoversafterrandomizationintheSTICHtrial ..................................... 61
Bhattathiri,P.S.,Gregson,B.,Prasad,K.S.M.,Mendelow,A.D.:
Intraventricularhemorrhageandhydrocephalusafterspontaneousintracerebralhemorrhage:results
fromtheSTICHtrial........................................................................................ 65
Ebihara,T.,Kinoshita,K.,Utagawa,A.,Sakurai,A.,Furukawa,M.,Kitahata,Y.,Tominaga,Y.,
Chiba,N.,Moriya,T.,Nagao,K.,Tanjoh,K.:
Changesincoagulativeandfibrinolyticactivitiesinpatientswithintracranialhemorrhage................ 69
Okuda,M.,Suzuki,R.,Moriya,M.,Fujimoto,M.,Chang,C.W.,Fujimoto,T.:
Thee¤ectofhematomaremovalforreducingthedevelopmentofbrainedemaincasesofputaminal
hemorrhage ................................................................................................. 74
Wu,G.,Xi,G.,Huang,F.:
Spontaneousintracerebralhemorrhageinhumans:hematomaenlargement,clotlysis,andbrainedema.. 78
Fainardi,E.,Borrelli,M.,Saletti,A.,Schivalocchi,R.,Russo,M.,Azzini,C.,Cavallo,M.,Ceruti,S.,
Tamarozzi,R.,Chieregato,A.:
Evaluationofacuteperihematomalregionalapparentdi¤usioncoe‰cientabnormalitiesbydi¤usion-
weightedimaging............................................................................................ 81
Tagliaferri,F.,Compagnone,C.,Fainardi,E.,Tanfani,A.,Pascarella,R.,Sarpieri,F.,Targa,L.,
Chieregato,A.:
Reperfusionoflowattenuationareascomplicatingsubarachnoidhemorrhage............................. 85
HumanCerebralIschemia
Nanda,A.,Vannemreddy,P.,Willis,B.,Kelley,R.:
Strokeintheyoung:relationshipofactivecocaineusewithstrokemechanismandoutcome.............. 91
Sakurai,A.,Kinoshita,K.,Inada,K.,Furukawa,M.,Ebihara,T.,Moriya,T.,Utagawa,A.,Kitahata,Y.,
Okuno,K.,Tanjoh,K.:
Brainoxygenmetabolismmayrelatetothetemperaturegradientbetweenthejugularveinand
pulmonaryarteryaftercardiopulmonaryresuscitation..................................................... 97
Contents XI
Imaging/Monitoring
Daley,M.L.,Le¿er,C.W.,Czosnyka,M.,Pickard,J.D.:
Intracranialpressuremonitoring:modelingcerebrovascularpressuretransmission........................ 103
Guendling,K.,Smielewski,P.,Czosnyka,M.,Lewis,P.,Nortje,J.,Timofeev,I.,Hutchinson,P.J.,
Pickard,J.D.:
UseofICMþsoftwareforon-lineanalysisofintracranialandarterialpressuresinhead-injuredpatients. 108
Czosnyka,M.,Hutchinson,P.J.,Balestreri,M.,Hiler,M.,Smielewski,P.,Pickard,J.D.:
Monitoringandinterpretationofintracranialpressureafterheadinjury................................... 114
ExperimentalBrainInjury
O’Connor,C.A.,Cernak,I.,Vink,R.:
Thetemporalprofileofedemaformationdi¤ersbetweenmaleandfemaleratsfollowingdi¤use
traumaticbraininjury....................................................................................... 121
James,H.E.:
Thee¤ectofintravenousfluidreplacementontheresponsetomannitolinexperimentalcerebraledema:
ananalysisofintracranialpressure,serumosmolality,serumelectrolytes,andbrainwatercontent ....... 125
Shigemori,Y.,Katayama,Y.,Mori,T.,Maeda,T.,Kawamata,T.:
Matrixmetalloproteinase-9isassociatedwithblood-brainbarrieropeningandbrainedemaformation
aftercorticalcontusioninrats .............................................................................. 130
Nakamura,T.,Miyamoto,O.,Yamashita,S.,Keep,R.F.,Itano,T.,Nagao,S.:
Delayedprecursorcellmarkerresponseinhippocampusfollowingcoldinjury-inducedbrainedema...... 134
Sakowitz,O.W.,Schardt,C.,Neher,M.,Stover,J.F.,Unterberg,A.W.,Kiening,K.L.:
Granulocytecolony-stimulatingfactordoesnota¤ectcontusionsize,brainedemaorcerebrospinalfluid
glutamateconcentrationsinratsfollowingcontrolledcorticalimpact...................................... 139
Li,S.,Kuroiwa,T.,Katsumata,N.,Ishibashi,S.,Sun,L.,Endo,S.,Ohno,K.:
Unilateralspatialneglectandmemorydeficitassociatedwithabnormalb-amyloidprecursorprotein
accumulationafterlateralfluidpercussioninjuryinMongoliangerbils.................................... 144
Ohsumi,A.,Nawashiro,H.,Otani,N.,Ooigawa,H.,Toyooka,T.,Yano,A.,Nomura,N.,Shima,K.:
Alterationofgapjunctionproteins(connexins)followinglateralfluidpercussioninjuryinrats ........... 148
Vannemreddy,P.,Ray,A.K.,Patnaik,R.,Patnaik,S.,Mohanty,S.,Sharma,H.S.:
ZincprotoporphyrinIXattenuatesclosedheadinjury-inducededemaformation,blood-brainbarrier
disruption,andserotoninlevelsintherat................................................................... 151
Uchino,H.,Morota,S.,Takahashi,T.,Ikeda,Y.,Kudo,Y.,Ishii,N.,Siesjo¨,B.K.,
Shibasaki,F.:
AnovelneuroprotectivecompoundFR901459withdualinhibitionofcalcineurinandcyclophilins....... 157
Ishikawa,Y.,Uchino,H.,Morota,S.,Li,C.,Takahashi,T.,Ikeda,Y.,Ishii,N.,Shibasaki,F.:
Searchfornovelgenemarkersoftraumaticbraininjurybytimedi¤erentialmicroarrayanalysis ......... 163
Zhao,F.Y.,Kuroiwa,T.,Miyasakai,N.,Tanabe,F.,Nagaoka,T.,Akimoto,H.,Ohno,K.,Tamura,A.:
Di¤usiontensorfeatureinvasogenicbrainedemaincats .................................................. 168
XII Contents
Beaumont,A.,Fatouros,P.,Gennarelli,T.,Corwin,F.,Marmarou,A.:
BolustracerdeliverymeasuredbyMRIconfirmsedemawithoutblood-brainbarrierpermeabilityin
di¤usetraumaticbraininjury ............................................................................... 171
ExperimentalIntracranialHemorrhage
Wagner,K.R.,Beiler,S.,Beiler,C.,Kirkman,J.,Casey,K.,Robinson,T.,Larnard,D.,deCourten-
Myers,G.M.,Linke,M.J.,Zuccarello,M.:
Delayedprofoundlocalbrainhypothermiamarkedlyreducesinterleukin-1bgeneexpressionand
vasogenicedemadevelopmentinaporcinemodelofintracerebralhemorrhage............................ 177
Shao,J.,Xi,G.,Hua,Y.,Schallert,T.,Felt,B.T.:
Alterationsinintracerebralhemorrhage-inducedbraininjuryintheirondeficientrat ..................... 183
Ostrowski,R.P.,Colohan,A.R.T.,Zhang,J.H.:
Neuroprotectivee¤ectofhyperbaricoxygeninaratmodelofsubarachnoidhemorrhage ................. 188
Nakamura,T.,Keep,R.F.,Hua,Y.,Nagao,S.,Ho¤,J.T.,Xi,G.:
Iron-inducedoxidativebraininjuryafterexperimentalintracerebralhemorrhage.......................... 194
Wan,S.,Hua,Y.,Keep,R.F.,Ho¤,J.T.,Xi,G.:
DeferoxaminereducesCSFfreeironlevelsfollowingintracerebralhemorrhage........................... 199
Yang,S.,Hua,Y.,Nakamura,T.,Keep,R.F.,Xi,G.:
Up-regulationofbrainceruloplasmininthrombinpreconditioning........................................ 203
Lodhia,K.R.,Shakui,P.,Keep,R.F.:
Hydrocephalusinaratmodelofintraventricularhemorrhage ............................................. 207
Kawai,N.,Nakamura,T.,Nagao,S.:
EarlyhemostatictherapyusingrecombinantfactorVIIaincollagenase-inducedintracerebral
hemorrhagemodelinrats................................................................................... 212
Nakamura,T.,Xi,G.,Keep,R.F.,Wang,M.,Nagao,S.,Ho¤,J.T.,Hua,Y.:
E¤ectsofendogenousandexogenousestrogenonintracerebralhemorrhage-inducedbraindamagein
rats.......................................................................................................... 218
Cannon,J.R.,Nakamura,T.,Keep,R.F.,Richardson,R.J.,Hua,Y.,Xi,G.:
Dopaminechangesinaratmodelofintracerebralhemorrhage ............................................ 222
Yang,S.,Nakamura,T.,Hua,Y.,Keep,R.F.,Younger,J.G.,Ho¤,J.T.,Xi,G.:
IntracerebralhemorrhageincomplementC3-deficientmice................................................ 227
Gong,Y.,Tian,H.,Xi,G.,Keep,R.F.,Ho¤,J.T.,Hua,Y.:
Systemiczincprotoporphyrinadministrationreducesintracerebralhemorrhage-inducedbraininjury..... 232
ExperimentalCerebralIschemia
Ito,U.,Kawakami,E.,Nagasao,J.,Kuroiwa,T.,Nakano,I.,Oyanagi,K.:
Restitutionofischemicinjuriesinpenumbraofcerebralcortexaftertemporaryischemia ................. 239
Luo,J.,Chen,H.,Kintner,D.B.,Shull,G.E.,Sun,D.:
InhibitionofNaþ/Hþ exchangerisoform1attenuatesmitochondrialcytochromeCreleaseincortical
neuronsfollowinginvitroischemia......................................................................... 244