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Bone 1993: Vol 14 Index & Table of Contents PDF

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BONE CELL & MOLECULAR BIOLOGY PATHOPHYSIOLOGY ® TREATMENT VOLUME 14, 1993 LIST OF CONTENTS AND AUTHOR INDEX ©) PERGAMON PRESS _ NewYork = Oxford @ Seoul # Tokyo BONE CELL & MOLECULAR BIOLOGY PATHOPHYSIOLOGY ® TREATMENT AMERICAN EDITORIAL OFFICES EUROPEAN EDITORIAL OFFICES ASIAN EDITORIAL OFFICES EDITOR: Roland Baron EDITOR: John Kanis EDITOR: Etsuro Ogata Departments of Orthopaedics and Cell Department of Human Metabolism Japanese Foundation for Cancer Research Biology University of Sheffield Medical School Cancer Institute Hospital Yale University School of Medicine Beech Hill Road Kami-Ikabukuro 1-37-1 P.O. Box 208044 Sheffield, $10 2RX, UK Toshima-ku 333 Cedar Street, SHM IES5 44 (742) 739176 Tokyo 170, Japan New Haven, CT 06520-8044 FAX 44 (742) 739826 81-339-18-0111 (203) 785-4150 FAX 81 353 94 3886 FAX (203) 785-2744 ASSOCIATE EDITORS ASSOCIATE EDITORS ASSOCIATE EDITORS Herbert Fleisch Tatsuo Suda Ernesto Canalis Pathologisches Institut der Universitat Department of Biochemistry Endocrine-Metabolic Section Bern Showa University School of Dentistry St. Francis Hospital and Medical Center Murtenstrasse 35, 3010 Bern, Switzerland 1-5-8 Hatanodai 114 Woodland Street 31-64-25-18 Shinagawa-ku, Tokyo 142, Japan Hartford, CT 06105 81-3-784-8162 (203) 548-4068 Jean-Philippe Bonjour David Goltzman Division de Physiopathologie Clinique Hideaki E. Takahashi Calcium Research Laboratory H6pital Cantonal Universitaire de Genéve Department of Orthopedic Surgery Royal Victoria Hospital 24 rue Micheli du Crest Niigata University School of 687 Pine Avenue West 1211 Genéve 4, Switzerland Medicine Montreal 43A 1A1, Canada 41-22-226620 1-757 Asahimachi-dori (514) 843-1632 Niigata, Niigata 951, Japan FAX (514) 982-0872 81-25-229-1674 Honorary Editor: Ralph S. Goldsmith Managing Editor: Toshio Matsumoto EDITORIAL BOARD Clarke H. Anderson, Kansas City (USA) Helen L. Henry, Riverside (USA) Anthony W. Norman, Riverside (USA) Claude D. Arnaud, San Francisco (USA) Keith A. Hruska, St. Louis (USA) Maureen E. Owen, Oxford (England) Sara B. Arnaud, Moffett Field (USA) Webster S. S. Jee, Salt Lake City (USA) Hidehiro Ozawa, Niigata (Japan) Jane E. Aubin, Toronto (Canada) Arnold J. Kahn, San Francisco (USA) A. Michael Parfitt, Detroit (USA) David J. Baylink, Loma Linda (USA) Michael Kleerekoper, Detroit (USA) William A. Peck, St. Louis (USA) Olav Bijvoet, Leiden (Netherlands) Stephen M. Krane, Boston (USA) Meinrad Peterlik, Vienna (Austria) Itzhak Binderman, Tel Aviv (Israel) Masayoshi Kumegawa, Saitamo (Japan) Solomon Posen, St. Leonards (Australia) Jean-Philippe Bonjour, Geneve (Switzerland) Takahide Kurokawa, Tokyo (Japan) Lawrence G. Raisz, Farmington (USA) Alan Boyde, London (England) Joseph M. Lane, New York (USA) Howard Rasmussen, Augusta (USA) Arthur E. Broadus, New Haven (USA) Robert Lindsay, West Haverstraw (USA) Robert R. Recker, Omaha (USA) Christopher E. Cann, San Francisco (USA) Paul T. Lips, Amsterdam (Netherlands) Eberhard Ritz, Heidelberg (Germany) Claus Christiansen, Glostrop (Denmark) Iain MacIntyre, London (England) Gideon A. Rodan, West Point (USA) Pierre D. Delmas, Lyon (France) T. J. Martin, Victoria (Australia) R. G. G. Russell, Sheffield (England) Erik F. Eriksen, Aarhus (Denmark) Sandy C. Marks, Worcester (USA) Fujio Suzuki, Osaka (Japan) Jan A. Fischer, Zurich (Switzerland) Richard B. Mazess, Madison (USA) Steven L. Teitelbaum, St. Louis (USA) Takuo Fujita, Hyogo (Japan) Flemming Melsen, Aahus (Denmark) John D. Termine, Indianapolis (USA) Robert F. Gagel, Houston (USA) Pierre Meunier, Lyon (France) Gilbert Vaes, Brussels (Belgium) Carlo Gennari, Siena (Italy) Scott C. Miller, Salt Lake City (USA) Shlomo Wientroub, Tel Aviv (Israel) Francis H. Glorieux, Montreal (Canada) Gregory R. Mundy, San Antonio (USA) Thomas J. Wronski, Gainesville (USA) Steve Goldring, Boston (USA) Robert Neer, Cambridge (USA) Roy E. Wuthier, Columbia (USA) John G. Haddad, Philadelphia (USA) Peter J. Nijweide, Leiden (Netherlands) Alberta M. Zambonin-Zallone, Bari (Italy) Robert P. Heaney, Omaha (USA) Production Editor: Bruce Cooper, Pergamon Press, Tarrytown, New York. Manuscript Submissions: Manuscripts should be-addressed to any of the Editors or Associate Editors (see addresses listed above). Publishing, Subscription, and Advertising Offices: Pergamon Press Inc., 660 White Plains Road, Tarrytown, NY 10591-5153, USA, E-mail Address: [email protected]; or Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, England. Published Bimonthly: Annual Instituticnal Subscription Rates 1994: North, Central, and South America, U.S.$735.00, Rest of World £478.00. Associated Personal Subscription Rates are available on request for those whose institutions are library subscribers. Sterling prices exclude VAT. Non-VAT registered customers in the European Community will be charged the appropriate VAT in addition to the price listed. Prices include postage and insurance and are subject to change without notice. Bone, 14, pp. IlI-XV, (1993) 8756-3282/93 $6.00 + 00 Printed in the USA. All rights reserved. Copyright © 1993 Pergamon Press Ltd. Volume 14, Number 1, 1993 ORIGINAL ARTICLES Li. Mosekilde, C. C. Danielsen and U. B. Knudsen The Effect of Aging and Ovariectomy on the Vertebral Bone Mass and Biomechanical Properties of Mature Rats ... S. Suzuki, M. Koga, K. Takaoka, K. Ono and B. Sato Effects of Retinoic Acid on Steroid and Vitamin D, Receptors in Cultured Mouse Osteosarcoma Cells A. L. Wucherpfennig, F. E. Dewhirst and P. Stashenko Platelet Activating Factor Increases Intracellular Calcium in Isolated Osteoclasts But Does Not Modify Bone Resorption Li. Mosekilde and B. Bak The Effects of Growth Hormone on Fracture Healing in Rats: A Histological Description M. Wakasugi, R. Wakao, M. Tawata, N. Gan, K. Koizumi and T. Onaya Bone Mineral Density Measured by Dual Energy X-ray Absorptiometry in Patients with Non-Insulin-Dependent Diabetes Mellitus S. Shibata, O. Baba, Y. Sakamoto, M. Ohsako, Y. Yamashita and T. Ichijo An Ultrastructural Study of the Mitotic Preosteoblasts in the Primary Spongiosa of the Rat Mandibular Condyle.... C. Cooper, P. Hannaford, P. Croft and C. R. Kay Oral Contraceptive Pill Use and Fractures in Women: A Prospective Study K. Sato, Y. Nishii, F. N. Woodiel and L. G. Raisz Effects of Two New Vitamin D, Derivatives, 22-Oxa-la-25-Dihydroxyvitamin D, (OCT) and 2B-(3-Hydroxypropoxy)-1a,25-Dihydroxyvitamin D, (ED-71), on Bone Metabolism in Organ Culture D. L. Cochran, C. A. Rouse, S. E. Lynch and D. T. Graves Effects of Platelet-Derived Growth Factor Isoforms on Calcium Release from Neonatal Mouse Calvariae A. P. Mee, M. T. Gordon, C. May, D. Bennett, D. C. Anderson and P. T. Sharpe Canine Distemper Virus Transcripts Detected in the Bone Cells of Dogs with Metaphyseal Osteopathy Abstracts from the Advances in Renal Osteodistrophy Symposium Volume 14, Number 2, 1993 ORIGINAL ARTICLES Y. Ishida and S. Kawai Characterization of Cultured Cells Derived from Ossification of the Posterior Longitudinal Ligament of the Spine... 85 H. Rico, M. Revilla, E. R. Hernandez, F. Gémez-Castresana and L. F. Villa Bone Mineral Content and Body Composition in Postpubertal Cyclist Boys M. Zaidi, A. S. M. T. Alam, B. E. Bax, V. S. Shankar, C. M. R. Bax, J. S. Gill, M. Pazianas, C. L.-H. Huang, T. Sahinoglu, B. S. Moonga, C. R. Stevens and D. R. Blake Role of the Endothelial Cell in Osteoclast Control: New Perspectives Ill IV List of Contents S. Mori and D. B. Burr Increased Intracortical Remodeling Following Fatigue Damage H. Ohta, T. Ikeda, T. Masuzawa, K. Makita, Y. Suda and S. Nozawa Differences in Axial Bone Mineral Density, Serum Levels of Sex Steroids, and Bone Metabolism between Postmenopausal and Age- and Body Size-Matched Premenopausal Subjects T. Tanaka, Y. Taniguchi, K. Gotoh, R. Satoh, M. Inazu and H. Ozawa Morphological Study of Recombinant Human Transforming Growth Factor B,-Induced Intramembranous Ossification in Neonatal Rat Parietal Bone B. M. Mortensen, H. P. Aarseth, R. Ganss, E. Haug, K. M. Gautvik and J. O. Gordeladze 24,25-Dihydroxy Vitamin D, Treatment Inhibits Parathyroid-Stimulated Adenylate Cyclase in Iliac Crest Biopsies from Uremic Patients E. De Bisschop, R. Luypaert, O. Louis and M. Osteaux Fat Fraction of Lumbar Bone Marrow Using In Vivo Proton Nuclear Magnetic Resonance Spectroscopy S. Giannini, A. D’Angelo, L. Malvasi, R. Castrignano, T. Pati, R. Tronca, L. Liberto, M. Nobile and G. Crepaldi Effects of One-Year Cyclical Treatment with Clodronate on Postmenopausal Bone Loss S. C. Miller and S. C. Marks, Jr. Local Stimulation of New Bone Formation by Prostaglandin E,: Quantitative Histomorphometry and Comparison of Delivery by Minipumps and Controlled-Release Pellets H. Maeda, D. B. Kimmel, D. M. Raab and N. E. Lane Musculoskeletal Recovery Following Hindlimb Immobilization in Adult Female Rats M. K. Karlsson, O. Johnell, B. E. Nilsson, I. Sernbo and K. J. Obrant Bone Mineral Mass in Hip Fracture Patients P. Pietschmann, K. H. Farsoudi, O. Hoffmann, K. Klaushofer, H. Hérandner and M. Peterlik Inhibitory Effect of Amylin on Basal and Parathyroid Hormone-Stimulated Bone Resorption in Cultured Neonatal Mouse Calvaria A. Odgaard and H. J. G. Gundersen Quantification of Connectivity in Cancellous Bone, with Special Emphasis on 3-D Reconstructions Letter to the Editor Volume 14, Number 3, 1993 Special Issue Bone Morphometry 1992 Sixth International Congress Proceedings Lexington, Kentucky, October 4-9 Group Photo of Bone Morphometry 1992 List of Participants List of Contents BONE STRUCTURE: New Perspectives J. E. Compston, N. J. Garrahan, P. 1. Croucher, C. D. P. Wright and K. Yamaguchi Quantitative Analysis of Trabecular Bone Structure A. Vesterby Marrow Space Star Volume Can Reveal Change of Trabecular Connectivity M. Vogel, M. Hahn and G. Delling Relation Between 2- and 3-Dimensional Architecture of Trabecular Bone in the Human Spine A. Boyde, J. C. Elliott and S. J. Jones Stereology and Histogram Analysis of Backscattered Electron Images: Age Changes in Bone D. H. Birkenhager-Frenkel, A. L. Nigg, C. J. J. Hens and J. C. Birkenhager Changes of Interstitial Bone Thickness with Age in Men and Women H. J. G. Gundersen, R. W. Boyce, J. R. Nyengaard and A. Odgaard The ConnEulor: Unbiased Estimation of Connectivity Using Physical Disectors under Projection BONE MORPHOMETRY IN ORTHOPEDIC SURGERY B. K. Bay, R. B. Martin, N. A. Sharkey and M. W. Chapman Repair of Large Cortical Defects with Block Coralline Hydroxyapatite L. D. Dorr, M.-C. Faugere, A. M. Mackel, T. A. Gruen, B. Bognar and H. H. Malluche Structural and Cellular Assessment of Bone Quality of Proximal Femur D. S. Metsger, I. Arnala, M.-C. Faugere and H. H. Malluche Histomorphometric Analysis of Tricalcium Phosphate Ceramic Implanted into Turkeys J. M. Zanelli, J. Pearson, S. T. Moyes, J. Green, J. Reeve, N. J. Garrahan, M. R. Stanton, J.-P. Roux, M. E. Arlot and P. J. Meunier Methods for the Histological Study of Femoral Neck Bone Remodelling in Patients with Fractured Neck of Femur .. BONE BIOMECHANICS: Relationship with Bone Morphometry T. S. Horn The Identification of Cortical Microdamage in Fatigue-Loaded Bone Using a Non-Invasive Impulse Response Vibration Testing Technique J. L. Ferretti, R. F. Capozza, N. Mondelo, E. Montuori and J. R. Zanchetta Determination of Femur Structural Properties by Geometric and Material Variables as a Function of Body Weight in Rats. Evidence of Sexual Dimorphism HORMONES, GROWTH FACTORS, PROSTAGLANDINS AND BONE E. Canalis Insulin Like Growth Factors and the Local Regulation of Bone Formation M. Gunness and J. M. Hock Anabolic Effect of Parathyroid Hormone on Cancellous and Cortical Bone Histology M. Li, W. S. S. Jee, H. Z. Ke, X. G. Liang, B. Y. Lin, Y. F. Ma and R. B. Setterberg Prostaglandin E, Restores Cancellous Bone to Immobilized Limb and Adds Bone to Overloaded Limb in Right PUN MEAN NOsS RM REINO hoc a ccancen dav graa sda eau ade tan yadaadasi wos nana avade gee cescaayecre(hcedep abendasetacnanaenscnedodecdaaees E. L. Khoury and C. D. Arnaud Alkaline Phosphatase-Positive Human Osteoblasts Do Not Normally Express MHC Class II Antigens In Vivo J. M. Lean, J. W. M. Chow and T. J. Chambers Estrogen Induces Bone Formation on Non-Resorptive Surfaces in the Rat VI List of Contents NEW FRONTIERS IN BONE MORPHOMETRY I: Immunocytochemistry and In Situ Hybridization R. A. Dodds, K. Merry, A. Littlewood and M. Gowen A Method for the Localization of Cytokine mRNA Expression in Adult Human Bone by In Situ Hybridization R. S. Tuan Analysis of Gene Expression in Skeletal Tissues by In Situ Hybridization P. Bianco, J. N. Bradbeer, M. Riminucci and A. Boyde Marrow Stromal (Westen-Bainton) Cells: Identification, Morphometry, Confocal Imaging and Changes in Disease P. Ballanti, J. N. Bradbeer, E. Bonucci, G. Coen, S. Mazzaferro and P. Bianco Evaluation of Osteoblastic Activity by Morphometric Comparison of Alkaline Phosphatase Cytochemistry vs. Tetracycline Fluorescence S. Matsunaga, K. Ijiri, T. Sakou and N. Morimoto Immunohistochemical Study of Activating Osteoblasts from Undifferentiated Mesenchymal Cells by Electrical Stimulation NEW FRONTIERS IN BONE MORPHOMETRY II: Use of Transgenic Mice—Novel Techniques B. F. Boyce, H. Chen, P. Soriano and G. R. Mundy Histomorphometric and Immunocytochemical Studies of src-Related Osteopetrosis K. Lee, J. D. Deeds, A. T. Bond, H. Jiippner, A.-B. Abou-Samra and G. V. Segre In Situ Localization of PTH/PTHrP Receptor mRNA in the Bone of Fetal and Young Rats S. M. Pockwinse, J. B. Lawrence, R. H. Singer, J. L. Stein, J. B. Lian and G. S. Stein Gene Expression at Single Cell Resolution Associated with Development of the Bone Cell Phenotype: Ultrastructural and In Situ Hybridization Analysis ANIMAL MODELS FOR METABOLIC BONE DISEASES J. W. M. Chow, S. Badve and T. J. Chambers A Comparison of Microanatomic Basis for Coupling between Bone Formation and Bone Resorption in Man and the Rat R. W. Norrdin, K. S. Moffat, M. A. Thrall and P. W. Gasper Characterization of Osteopenia in Feline Mucopolysaccharidosis VI and Evaluation of Bone Marrow Transplantation Therapy J. B. Rodgers, M.-C. Monier-Faugere and H. Malluche Animal Models for the Study of Bone Loss after Cessation of Ovarian Function L. Mosekilde, S. E. Weisbrode, J. A. Safron, H. F. Stills, M. L. Jankowsky, D. C. Ebert, C. C. Danielsen, C. H. Sogaard, A. F. Franks, M. L. Stevens, C. L. Paddock and R. W. Boyce Calcium-Restricted Ovariectomized Sinclair S-1 Minipigs: An Animal Model of Osteopenia and Trabecular Plate Perforation C. M. Schnitzler, U. Ripamonti and J. M. Mesquita Bone Histomorphometry in Baboons in Captivity K. Lundon and M. Grynpas The Longterm Effect of Ovariectomy on the Quality and Quantity of Cortical Bone in the Young Cynomolgus Monkey: A Comparison of Density Fractionation and Histomorphometric Techniques RENAL OSTEODYSTROPHY AND OTHER METABOLIC BONE ABNORMALITIES E. F. Eriksen, H. Kudsk, K. Emmertsen, L. Mosekilde and F. Melsen Bone Remodeling during Calcitonin Excess: Reconstruction of the Remodeling Sequence in Medullary Thyroid Carcinoma List of Contents P. Christiansen, T. Steiniche, H. Brockstedt, L. Mosekilde, 1. Hessov and F. Melsen Primary Hyperparathyroidism: Iliac Crest Cortical Thickness, Structure and Remodeling Evaluated by Histomorphometric Methods E. P. Boling, C. Primavera, G. Friedman, M. King, L. Bosserman, E. E. Schulz and W. G. Goodman Non-Invasive Measurements of Bone Mass in Adult Renal Osteodystrophy G. Coen, P. Ballanti, S. Mazzaferro, M. Pasquali and E. Bonucci Procollagen Type 1 C-Terminal Extension Peptide, PTH and 1,25(OH),D, in Chronic Renal Failure Y. Tsukamoto, R. Mariyo, Y. Nomura, N. Sato, M.-C. Faugere and H. H. Malluche Long-Term Effect of Oral Calcitriol Pulse Therapy on Bone in Hemodialysis Patients T. H. Ittel, U. Gladziwa and H. G. Sieberth Synergistic Effect of 1,25-Vitamin D, and Fluoride on Bone Aluminum Accumulation BONE RESORPTION: Morphometric Approaches A. M. Parfitt Morphometry of Bone Resorption: Introduction and Overview E. F. Eriksen Assessment of Erosion Depth by Lamellar Counting P. |. Croucher, N. J. Garrahan and J. E. Compston Assessment of Resorption Cavity Characteristics in Trabecular Bone: Changes in Primary and Secondary Osteoporosis S. J. Jones and A. Boyde Histomorphometry of Howship’s Lacunae Formed In Vivo and In Vitro: Depths and Volumes Measured by Scanning Electron and Confocal Microscopy BONE FORMATION: New Developments P. J. Marie and M. C. de Vernejoul Proliferation of Bone Surface-Derived Osteoblastic Cells and Control of Bone Formation B. Hinrichs, T. Dreyer, A. Battmann and A. Schulz Histomorphometry of Active Osteoblast Surface Labelled by Antibodies against Non-Collagenous Bone Matrix Proteins M. E. A. Brown, M. E. Arlot and J. Reeve Osteoblast Density and the Evolution of BMUs in Vertebral Osteoporosis H. Z. Ke, W. S. S. Jee, H. Ito, R. B. Setterberg, M. Li, B. Y. Lin, X. G. Liang and Y. F. Ma Greater Bone Formation Induction Occurred in Aged than Young Cancellous Bone Sites S. M. Ott Calculation of Active Formation Period Using Label Escape and Three Labels QUANTITATIVE ASSESSMENT OF THE EFFECTS OF BISPHOSPHONATES AND CALCITONIN ON BONE W.S. S. Jee, L. Tang, H. Z. Ke, R. B. Setterberg and D. B. Kimmel Maintaining Restored Bone with Bisphosphonate in the Ovariectomized Rat Skeleton: Dynamic Histomorphometry of Changes in Bone Mass R. Balena, A. Markatos, M. Gentile, P. Masarachia, J. G. Seedor, G. A. Rodan and M. Yamamoto The Aminobisphosphonat te Alendronate Inhibits Bone Loss Induced by Thyroid Hormone in the Rat: Comparison between Effects on Tibiae and Vertebrae Vill List of Contents M. E. Cohen-Solal, C. Roux, A. Valentin-Opran, M. Dougados, B. Amor and M. C. de Vernejoul Histomorphometric Effect of Six Month Treatment with Oral Risedronate in Patients with Multiple Myeloma T. M. Skerry and L. E. Lanyon Immobilisation Induced Bone Loss in the Sheep Is Not Modulated by Calcitonin Treatment OSTEOPOROSIS: Histomorphometric Studies M.-S. Shih, M. A. Cook, C. A. Spence, S. Palnitkar, H. McElroy and A. M. Parfitt Relationship between Bone Formation Rate and Osteoblast Surface on Different Subdivisions on the Endosteal Envelope in Aging & Osteoporosis A. B. Hodsman and B. M. Steer Early Histomorphometric Changes in Response to Parathyroid Hormone Therapy in Osteoporosis: Evidence for de novo Bone Formation on Quiescent Cancellous Surfaces TECHNICAL DEVELOPMENTS FOR BONE MORPHOMETRY H. E. Gruber In Vitro Tetracycline Labelling and Bone Cell Survival in Human Trabecular Bone Explants M. Mendes and K. P. H. Pritzker Optimizing Multiple Fluorochrome Bone Histodynamic Markers H. M. Theuns, H. Bekker, H. Fokkenrood and E. Offerman Methyl-Methacrylate Embedding of Undecalcified Rat Bone and Simultaneous Staining for Alkaline and Tartrate Resistant Acid Phosphatase S. Palle, C. Genty, L. Vanelle and C. Alexandre Electron Microscope Examination of Osteoblast-Like Cells (ROS 17/2.8) after Colorimetric Evaluation of the Proliferation WORKSHOP: QUALITY CONTROL IN BONE MORPHOMETRY M. C. Monier-Faugere Quality Assurance—Quality Control in Bone Histopathology and Bone Histomorphometry BONE MORPHOMETRY FOR ORAL AND MAXILLOFACIAL ABNORMALITIES J. Hollinger Strategies for Regenerating Bone of the Craniofacial Complex T. B. Aufdemorte, W. C. Fox, D. Miller, K. Buffum, G. R. Holt and K. D. Carey A Non-Human Primate Model for the Study of Osteoporosis and Oral Bone Loss 581 S.C. Miller and S. C. Marks, Jr. - ts Alveolar Bone Augmentation following the Local Administration of Prostaglandin E, by Controlled-Release Pellets . 587 Volume 14, Number 4, 1993 REVIEW ARTICLE C. H. Turner and D. B. Burr Basic Biomechanical Measurements of Bone: A Tutorial List of Contents ORIGINAL ARTICLES L. D. Swain, Z. Schwartz, K. Caulfield, B. P. Brooks and B. D. Boyan Nongenomic Regulation of Chondrocyte Membrane Fluidity by 1,25-(OH),D, and 24,25-(OH),D, Is Dependent on Cell Maturation J. H. Tobias, J. W. M. Chow and T. J. Chambers 3-Amino-1-Hydroxypropylidine-1-Bisphosphonate (AHPrBP) Suppresses Not Only the Induction of New, but Also the Persistence of Existing Bone-Forming Surfaces in Rat Cancellous Bone J. E. Anderson, D. L. Lentz and R. B. Johnson Recovery from Disuse Osteopenia Coincident to Restoration of Muscle Strength in mdx Mice M. C. H. van der Meulen, G. S. Beaupré and D. R. Carter Mechanobiologic Influences in Long Bone Cross-Sectional Growth J. A. Falch, T. S. Kaastad, G. Bohler, J. Espeland and O.-J. Sundsvold Secular Increase and Geographical Differences in Hip Fracture Incidence in Norway G. J. Salem, R. F. Zernicke, D. A. Martinez and A. C. Vailas Adaptations of Immature Trabecular Bone to Moderate Exercise: Geometrical, Biochemical, and Biomechanical Correlates M. Nagai, Y. Suzuki and M. Ota Systematic Assessment of Bone Resorption, Collagen Synthesis, and Calcification in Chick Embryonic Calvaria In Vitro: Effects of Prostaglandin E, C. T. Begley, M. J. Doherty, D. P. Hankey and D. J. Wilson The Culture of Human Osteoblasts upon Bone Graft Substitutes G. @rtoft, Lis Mosekilde, C. Hasling and Leif Mosekilde Estimation of Vertebral Body Strength by Dual Photon Absorptiometry in Elderly Individuals: Comparison between Measurements of Total Vertebral and Vertebral Body Bone Mineral S. C. Marks, Jr., C. A. MacKay, M. E. Jackson, E. K. Larson, M. J. Cielinski, E. R. Stanley and S. L. Aukerman The Skeletal Effects of Colony-Stimulating Factor-1 in Toothless (Osteopetrotic) Rats: Persistent Metaphyseal Sclerosis and the Failure to Restore Subepiphyseal Osteoclasts H. Brockstedt, M. Kassem, E. F. Eriksen, L. Mosekilde and F. Melsen Age- and Sex-Related Changes in Iliac Cortical Bone Mass and Remodeling Abstracts from the Steroids and Bone Symposium Volume 14, Number 5, 1993 CASE REPORTS S. Minisola, E. Romagnoli, L. Scarnecchia, M. T. Pacitti, R. Rosso, V. Carnevale, G. Minisola and G. Mazzuoli Parathyroid Storm: Immediate Recognition and Pathophysiological Considerations X List of Contents G. W. Edelson, M.-S. Shih and A. M. Parfitt A Unique Case of Adult Hypophosphatemic Osteomalacia ORIGINAL ARTICLES H. E. Gruber Ultrastructural Alterations and Retention of the C-Propeptide of Type II Collagen in Human Chondrocytes Exposed In Vitro to Brefeldin A C. C. Pilbeam, C. B. Alander, H. A. Simmons and L. G. Raisz Comparison of the Effects of Various Lengths of Synthetic Human Parathyroid Hormone-Related Peptide (hPTHrP) of Malignancy on Bone Resorption and Formation in Organ Culture P. Chavassieux, G. Boivin, C. M. Serre and P. J. Meunier Fluoride Increases Rat Osteoblast Function and Population After In Vivo Administration but not After In Vitro Exposure M. D. Stone, D. J. Hosking, C. Garcia-Himmelstine, D. A. White, D. Rosenblum and H. G. Worth The Renal Response to Exogenous Parathyroid Hormone in Treated Pseudohypoparathyroidism K. Hasegawa, H. E. Takahashi, Y. Koga, T. Kawashima, T. Hara, Y. Tanabe and S. Tanaka Mechanical Properties of Osteopenic Vertebral Bodies Monitored by Acoustic Emission S. Naito, M. Ito, I. Sekine, M. Ito, T. Hirano, K. Iwasaki and M. Niwa Femoral Head Necrosis and Osteopenia in Stroke-Prone Spontaneously Hypertensive Rats (SHRSPs) P. Christiansen, T. Steiniche, H. Brockstedt, L. Mosekilde, I. Hessov and F. Melsen Primary Hyperparathyroidism: Iliac Crest Cortical Thickness, Structure, and Remodeling Evaluated by Histomorphometric Methods M. Thavarajah, D. B. Evans and J. A. Kanis Differentiation of Heterogeneous Phenotypes in Human Osteoblast Cultures in Response to 1,25-Dihydroxyvitamin D, T. M. Boyce and R. D. Bloebaum Cortical Aging Differences and Fracture Implications for the Human Femoral Neck B. M. Thomson, V. Dean, C. Farquharson and B. S. Noble Visualisation and Selective Elimination of a Subpopulation of Mitogen-Responsive Bone Marrow Stromal Cells Using Bromodeoxyuridine and Photo-Induced Cell Killing J. C. Woodard, G. Berra, B. Ruksan, B. Carrillo and G. Erdos Toxic Effects of Solanum Malacoxylon on Sheep Bone M. Iwamoto, K. Shibano, J. Watanabe, M. Asada-Kubota, R. Ogawa and S. Kanamura Culture of Marrow Stromal Cells Derived from Bone Marrow Specimens Formed at Fracture Site of Human Volume 14, Number 6, 1993 ORIGINAL ARTICLES D. Scott, H. Abu Damir, W. Buchan, A. Duncan and S. P. Robins Factors Affecting Urinary Pyridinoline and Deoxypyridinoline Excretion in the Growing Lamb

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