Bodies in Flux: Scientific Methods for Negotiating Medical Uncertainty PDF
Preview Bodies in Flux: Scientific Methods for Negotiating Medical Uncertainty
Bodies in Flux Teston_9780226450520 i 2/27/2017 12:20:19 PM Teston_9780226450520 ii 2/27/2017 12:20:19 PM Teston_9780226450520 iii 2/27/2017 12:20:19 PM Bodies in Flux Scientific MethodS for negotiating Medical Uncertainty Christa teston the UniverSity of chicago PreSS Chicago and London Teston_9780226450520 iii 2/27/2017 12:20:19 PM The University of Chicago Press, Chicago 60637 The University of Chicago Press, Ltd., London © 2017 by The University of Chicago All rights reserved. No part of this book may be used or reproduced in any manner whatsoever without written permission, except in the case of brief quotations in critical articles and reviews. For more information, contact the University of Chicago Press, 1427 E. 60th St., Chicago, IL 60637. Published 2017 Printed in the United States of America 26 25 24 23 22 21 20 19 18 17 1 2 3 4 5 ISBN- 13: 978- 0- 226- 45052- 0 (cloth) ISBN- 13: 978- 0- 226- 45066- 7 (paper) ISBN-1 3: 978- 0- 226- 45083- 4 (e- book) DOI: 10.7208/chicago/9780226450834/001.0001 Library of Congress Cataloging-in-Publication Data Names: Teston, Christa, author. Title: Bodies in flux : scientific methods for negotiating medical uncertainty / Christa Teston. Description: Chicago ; London : The University of Chicago Press, 2017. | Includes bibliographical references and index. Identifiers: LCCN 2016038464| ISBN 9780226450520 (cloth : alk. paper) | ISBN 9780226450667 (pbk. : alk. paper) | ISBN 9780226450834 (e-book) Subjects: LCSH: Evidence-based medicine. | Uncertainty (Information theory) Classification: LCC R723.7 .T47 2017 | DDC 616—dc23 LC record available at https://lccn.loc.gov/2016038464 ♾ This paper meets the requirements of ANSI/NISO Z39.48–1992 (Permanence of Paper). Teston_9780226450520 iv 2/27/2017 12:20:19 PM Teston_9780226450520 v 2/27/2017 12:20:19 PM For Lolly and Paw, with love Teston_9780226450520 v 2/27/2017 12:20:19 PM Teston_9780226450520 vi 2/27/2017 12:20:19 PM Teston_9780226450520 vii 2/27/2017 12:20:19 PM Contents Acknowledgments ix 1. Evidential Matter(s) 1 2. Evidencing Visuals 26 3. Assessing Evidence 60 4. Synthesizing Evidence 94 5. Computing Evidence 134 6. Dwelling with Disease 169 Appendix A. ODAC Hearings Post- Avastin, 2011–2013 (Not Including Pediatric Hearings) 187 Appendix B. CSR Outlines 197 Appendix C. Genetic Testing Methods and Techniques, 1950–1990 204 Notes 205 References 215 Index 233 Teston_9780226450520 vii 2/27/2017 12:20:19 PM Teston_9780226450520 viii 2/27/2017 12:20:19 PM ATAeuusttthhooonrr___9iiss7bb8nn0 226iixx4 50520 ix 222///222777///222000111777 111222:::222000:::111999 PPPMMM aCknowledgments The wise eyes and kind minds of countless colleagues, friends, and loved ones helped make this book what it is. We all have those people in our lives who help prepare us for the things we don’t yet know we’re going to write. For this, I offer thanks to Casey Boyle, Jim Brown, Davida Charney, William Hart- Davidson, Scott Graham, Brian McNely, Margaret Price, Nathaniel Rivers, Chad Wickman, and Greg Wilson. You may not have known it, but our back- stage brainstorming at conferences, seminars, and through various social media and e- mail exchanges helped shape this book. So many of you gave of your time and suffered through early prose, under- developed drafts, and half-b aked ideas. You are priceless. For their kindness, patience, and disciplinary expertise, I am grateful to Ellen Barton, Jonathan Buehl, Scott DeWitt, Wendy Hesford, Candice Lanius, Jim Phelan, Thomas Rickert, Cindy Selfe, Clay Spinuzzi, Pamela Takayoshi, Karen Thompson, and the three anonymous peer reviewers whose revision recommendations were worth their weight in gold. Informal conversations and interviews with a host of experts in science and medicine also influenced how I conceive of doing rhetoric while dwelling in a world full of contingencies. For this, I am thankful to the kind folks in the Ohio State University’s Division of Human Genetics, the College of Public Health, and departments of pathology, mathematics, psychology, and statis- tics. I’m thankful to the Association of Teachers of Technical Writing (http:// www .attw .org) and Technical Communication Quarterly for allowing me to adapt for chapter 2 of this book portions of my (2012) article, “Moving from Artifact to Action: A Grounded Investigation of Visual Displays of Evidence during Medical Deliberations.” It is a privilege to work alongside budding scholars who are also interested in questions about how to make more livable worlds. I am especially grate- ful to the graduate students in my fall 2015 Research Methods Seminar who, without knowing it, were in so many ways this book’s very first audience. Other institutional structures and actors helped bring this book to frui- tion, including the graduate program at Kent State University from which I hail. Its founder, the late Stephen P. Witte, made the study of workplace writ- ing and literacy in Kent State’s Literacy, Rhetoric, and Social Practice pro- gram possible. And although I never met the man, I could swear he sat on my [ ix ] AATeuusttthhooonrr___9iiss7bb8nn0 226iixx4 50520 ix 222///222777///222000111777 111222:::222000:::111999 PPPMMM
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