Biotechnology Unzipped Promises and Realities BIOTECHNOLOGY UNZIPPED PROMISES & REALITIES Eric S$. GRACE JOSEPLL HENRY PRESS. Washington, D.C. 1997 aera ELS “a JOSREH HINES PRPS. on imgeirso he NATIONAL ACADEME TESS. ra hy he al Sader a Senne ele thi ‘ceca eet 3 “ae gel of tag anak on seen “echr ge ak Teal tee widdly eee ps‘enna atthe abe an Henne seatra: Lolinncn be Wana ery af elence sade ot yal sea oa Ay wate. aig crcunons se wresemendareny ete thi Seuse ws Boe fe cetera Jn oot mrsrar he iw Us Sut anedany oferta neo Lary Cans Cal te Nar ne a esa vg Sank eM eluent agi uae bo aso TSE EMU HES SAT ONE ACADEMY PRESS ‘wagon D9 EID avert iphoaet e352 iho Wingo reece en ah our of ss verdad eter tonkeo wlng Pr earensd Syst 197 Bi. Gece. tag srr [bls Ue asagaunat an 8 Pinebio Gud Contents Prefece Chaster 1 How Blotochnotogy Came About What is neteclinalegy? Ta the begining, he voyager ant uke monk, 8 sxiking coincidence Colored bouies trait sia the lab Lo there be DNA, ‘Uamewelirg the dauble belie orm Hoss does DNA store information? Acopyin every call ‘What do genes du Protsin primer samples of pro Protsinsare es The amines acids Gears. proeins, ard youn eyes ‘Ihe poner ence [Natore. che experl packer “Hove genes make proteinn Daring mecieotide adventures Chapter 2 Tools in the Gonotic Engineering Workshop Why bacteria Ahead start « ‘cena sips Hackers and wakecule sippers Fist catch your DNA, DNA na tbe Making recombinant DNA Yueding neve genes inta edis Gene expression Croniag plants, animals Mouselocal anetodies DNA probes DNA“ fingenptiting” Pelpamsase chain ceaction . nd cols Chapter 3 Biotechnology and the Body ew pars fr ald Weallic th -Exumuples of conditians knowa to gene be The beginnings ReLOVEEUSES nnn ‘The cance: of sun lovers ‘The Human Genome Project ne thexepe The cautiauing story of gene thera ‘The impostance of ean cells Miczo2es in medicine Meu: ines ‘icin plants The inteciecon sory Genesand eacciaes Netuue’s snagic Dulles Designer drugs ‘A.cose study: eyptaphen Closing thoughts ‘he problem wich amtibioties 38 38 38 an 4 4 4s a8 8 x0 ey neipter 4 jotechnology on the Farm oF “Milking ie for lls wert 1 Let us spray 5 nsec: fasts 196 Developing regulations ws eat exprarations nd litte plant with a biy fulst€ soosansnennonce TIT ess and discases wt nz A varsatile hacterionn ws ne Weather and soil 1 Faumer-ceptical’ ew us (Closing thoughts Chapter S Biotechnology and the Environment 13 -Mxiobes dean 09 nnnuaninnns TE atenzed ofteaters : rnin EAL Microbes in niforrns wenn 18 ‘Add Liquid and str se 1B Miersbes as monitors : 19) Fingingthe riphr micrbes far the job —oneansemer 41 Aquckreading nse TAB “Miccobes.and mines as Hot becteria Golden harvest Calls keen working aller hey ‘re deac Anna angleto landscaping Of caabagesand metas ighting chernicals with chemicils ‘Making new Fels lecaic ees (Closing shoughes Chapter 6 Blotechnotogy In Seas and Trees sninar 181 An ocean of oppor nity ravine 162 onl is ir on 164 Gndersate~ drugs - 166 A cornucopia of chumicas vena, 18 Car parts from crabs 10 esearch and develapraent aL Cholers kits rnin VEE ee!s from the sex ‘Farming the seas Disescesand pollation Proven sh ‘Ths forest and the: Aharvest of wood Boildinghetter mroes Forests ofthe firures Ciosing thowgh s Chapier 7 Ethical Issues 1 Maing oninions 193 — 197 Aquestiomairs 197 senting peaple 200 ‘uoblems with patents 203 what cra he patented? 206 “rofiting rom the poor 20 Protecting consamers 208 Health ileromas at Geng therapy revisited US. Pater No, 5,399,346 Bios ara cons of gone therapy Fromethevs wer sted Postscrpt Glossary Fucthes Reading Internet Resonrces Inéex Plota Ciedits & Sources