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Biotechnology and Bioengineering 1999: Vol 63 Index PDF

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Biotechnology Dad Bioengineering Editor Douglas S. Clark tb Associate Editors James D Bryers Maria-Regina Kula j LJ ap r 1 e Ls Jonathan S. Dordick ' eg en Tadashi Matsunaga I ant Oy George Georgiou sity ¢ exa Elettherios T. Papoutsakis versity lettrey A. Hubbell f TH Z~ UTICN h aann d lTeochhnn icaVli llUanidvseernsi ty sity of Zurich Denmark Founding Editor: Elmer L. Gaden, /r., Univ Postmaster Advertising Sales: Reprints: k ) Manuscripts Manuscripts All Other Correspondence N\ k NY Subscription Price Editorial Production, John Wiley 8) we Le x, This paper meets the requirement of ANSI/NISO Z39.48-1992 Pee rmanen» ce of Paper) Biotechnology and Bioengineering Author Index to Volume 63 Acuna, M.I Blackall, L.L. See Bond, P.L., 50 Dahlems, U. See Mayer, A.F., 373 Pérez, | Boam, A.T. See Doig, S.D., 601 Davis, H.E. See Le Doux, J.M., 654 Microb Bond, P.L. de Koning, W. See Sipkema, E.M., 56 Biot Keller, J.; Blackall, L.1 Anaerobic de Sousa, P.C., Jr. See Foguel, D., 552 Wast Phosphate Release from Activated Deepika, N.-U.-A. See Agrawal, R., 249 Agrawal, R. Sludge with Enhanced Biological Demuth, B. See Dols, M., 308 1) Phosphorus Removal. A Possible Dexheimer, J. See Oerther, S., 206 | Mechanism of Intracellular pH Control, Diekmann, H. See Beuse, M., 410 507 Doig, S.D. 3 Bou, J.J. See Pérez-Camero, G., 110 Boam, A.1 Livingston, A.G.: Stuckey, Boudrant, J. See Gschaedler, A 9|4 D.C.: Epoxidatior of 1,7-Octadiene by Ahring, B.K. See Ar Boures, E. See Bousquet, M.-P., 730 Pseudomonas oleovorans in a Aldaz, A. See Lopez-l Bousquet, M.-P. Membrane Bioreactor, 601 Allan, V.J.M. S« Willemot, R.-M.; Monsan, P.; Boures Dols, M. Alves, S.S. See Mat E.: Enzymatic Synthesis of Unsaturated Remaud-Simeon, M.:; Willemot, R.-M Ameer, G.A. Fatty Acid Glucoside Esters for Demuth, B.; Jérdening, H.-J.: Buchholz Dermo-Cosmetic Applications K.; Monsan, P.: Kinetic Modeling of Bramble, J. See Muzzio, F.J., 185 Oligosaccharide Synthesis Catalyzed by Branlant, C. See Gschaedler, A Leuconostoc mesenteroides NRRI Briihlmann, F. B-1299 Dextransucrase, 308 Chen, W Tuning Bipheny| Donaldson, M. Dioxy genase for Extended Substrate ; Wood, H.A.; Kulakosky, P.¢ : Shuler, Angelidaki, I. Specificity, 544 M.L.: Glycosylation of a Recombinant Ell ird, | \ Buchholz, K. See Dols, M., 308 Protein in the Tn5B1-4 Insect Cell Line Model of Bull, A.T. See Hooker, A.D Influence of Ammonia, Time of ( omplex Substrates to Harvest, Temperature, and Dissolved allow, M.E. See Finlay. J.A., 8 Oxygen, 255 Anton, J. S L6pez-Lop arbonell, R.G. See Huang, P.Y., 633 Dordick, J.S. See Ru, M.T., 233 Araujo, M.L.( Pile arpenter, J.F. See Heller, M.C., 166 dos Santos, V.A.P.M. See Hellendoorn., | Cicwshes R.« Hokka, C.O Studies arrier, R.L. See Obradovic, B., 197 694 spiration Rate of Free and ‘hang, H.N. See Park, J.K., 116 Dowd, J.E. ‘havarie, C. See Jolicoeur, M., 224 ; Weber, L.; Rodriguez, B.; Piret, J.M.; hen, W. See Briihlmann, F., 544 Kwok, K.E Predictive Control of See Mulchandani, A., 216 Hollow-Fiber Bioreactors for the Archambault, J. Se« ‘hou, C.P. Production of Monoclonal Antibodies Aristidou, A.A. - Yu, C.-( Tseng, J.-H.; Lin, M.-L; Lin 484 K.-Y H.-K Genetic Manipulation to Identify Limiting Steps and Develop Strategies Eaves, C.J. See Zandstra, P.W., 493 for High-Le vel Expression of Penicillin Edwards, G.H. See Hu. Y.-C., 721 in Batch and Acylase in Escherichia coli, 263 Eliopoulos, E. See | abrou, N I > 322 Continu hristiansen, T. Ellegaard, L. See Angelidaki, I., 363 Asboth, B. See Sasvari, Z., 459 Spohr, A.B.:; Nielsen, J.: On-Line Study Erbeldinger, M. Auria, R. See Acufia, M.E., 175 of Growth Kinetics of Single Hyphae of Ni, X.; Halling, P.J.: Kinetics of | ae in a Flow Through Enzymatic Solid-to-Solid Peptide Bailey, J.E. See Kaufmann, H., 57 Synthesis: Intersubstrate Compound, Baines, A.J. See Hooker, A.D., 559 Substrate Ratio, and Mixing Effects, Balcarcel, R.R. See Follstad, B.D., 675 Expression of Soluble and 316 Basnakova, G. See Finlay. J.A.. 8 Catalytically Active Plant (Monocot) Ergas, S.J. Bédard, C. See Zeiser, A., 122 B-Glucosidases in fF 392 Shumway, | Fitch, M.W.; Neemann, Beeftink, H.H. See Marchal, L.M., 344 lapés, P. J.J.: Membrane Process for Biological Beenackers, A.A.C.M. See Sipkema, E.M Moran, C.; Infante, M.R Enzymatic Treatment of Contaminated Gas fh Synthesis of Arginine-Based Cationic Streams, 431 Behie, L.A. See Kallos, M.S., 47 Surfactants Esen, A. See Cicek, M., 392 Bennett, G.N. See Aristidou, A.A lark, D.S. See Ru, M.1 Exposito, E. See Lopez-Lopez, Bently, W.E. See Hu, Y.-¢ lonis, Y.D. See Labrou, N.E., 322 Bergsma, J. See Marchal, L.M ‘ongregado, F. See Pérez-Camero, G., 110 Fahnestock, P. See Muzzio, F.J., 185 Beuse, M. ‘onner, A. See Finlay, J.A., 87 Fann, C.H. Kopmann, A.; Diekmann, H Thoma ‘onverti, A. See Palazzi, E., 273 Guarna, M.M.; Kilburn, D.G.: Piret, M.: Oxygen, pH Value ind Carbon Cooney, C.L. See Ameer, G.A., 618 J.M.: Relationship Between Source Induced ( hanges of the Mode of Coughlin, R.W. See Schreyer, H.B., 129 Recombinant Activated Protein C (O scillation in Synchronous Continuous Secretion Rates and mRNA Levels in ulture of Saccharomyce erevisiae da Fonseca, M.M.R. See Mateus, D.M.R.. Baby Hamster Kidney Cells, 464 110 625 Ferrasson, E. See Michon, T., 449 Biotechnology and Bioengineering, Vol. 63, Pp. 760-763 (1999) Fiefler, R.G. See Smets, B.F., 642 McFarlane, C.M.: Use of Multi-Staining Kallos, M.S. Finlay, J.A. Flow Cytometry to Characterise the ; Behie, L.A Inoculation and Growth ; Allan, V.J.M.; Conner, A.; Callow, Physiological State of Escherichia coli Conditions for High-Cell-Density M.E.; Basnakova, G.; Macaskie, L.E.: W3110 in High Cell Density Fed-Batch Expansion of Mammalian Neural Stem Phosphate Release and Heavy Metal Cultures, 705 Cells in Suspension Bioreactors, 473 Accumulation by Biofilm-Immobilized Higashiyama, K. Kamen, A.A. See Zeiser, A., 122 and Chemically-Coupled Cells of a ; Murakami, K.; Tsujimura, H.; Kaneva, I. See Mulchandani, A., 216 Citrobacter sp. Pre-Grown in Matsumoto, N.; Fujikawa, S.: Effects of Kaufmann, H. Continuous Culture, 87 Dissolved Oxygen on the Morphology ; Mazur, X.; Fussenegger, M.; Bailey Fitch, M.W. See Ergas, S.J., 431 of an Arachidonic Acid Production by J.E.: Influence of Low Temperature on Foguel, D. Mortierella alpina \S-4, 442 Productivity, Proteome and Protein ; Robinson, C.R.; de Sousa, P.C., J1 Hill, C.G., Jr. See Rice, K.E., 33 Phosphorylation of CHO Cells, 5 Silva, J.L.; Robinson, A.S.: Hydrostatic Hoare, M. See Tsoka, S., 290 Keller, J. See Bond, P.L.. 507 Pressure Rescues Native Protein from ; See Yeung, K.S.Y., 684 Kilburn, D.G. See Fann, C.H., 464 Aggregates, 552 Hokka, C.O. See Araujo, M.L.G.C., 593 ; See Zandstra, P.W., 493 Follstad, B.D. Holwill, I. See Tsoka, S., 290 Klibanov, A.M. See Knubovets, T., 242 ; Balcarcel, R.R.; Stephanopoulos, G.:; Hooker, A.D. Knubovets, T. Wang, D.1.C.: Metabolic Flux Analysis ; Green, N.H.; Baines, A.J.; Bull, A.T.; ; Osterhout, J.J Klibanov, A.M of Hybridoma Continuous Culture Jenkins, N.; Strange, P.G.; James, D.C Structure of Lysozyme Dissolved in Steady State Multiplicity, 675 Constraints on the Transport and Neat Organic Solvents as Assessed by Fortin, J.A. See Jolicoeur, M., 224 Glycosylation of Recombinant IFN-y in NMR and CD Spectroscopies, 242 Freed, L.E. See Obradovic, B., 197 Chinese Hamster Ovary and Insect Kopmann, A. See Beuse, M., 410 Fregapane, G. Cells, 559 Kroner, K.-H. See Vogel, J.H., 663 ; Rubio-Fernandez, H.; Nieto, J.; Hu, Y.-C. Kulakosky, P.C. See Donaldson, M., 255 Salvador, M.D.: Wine Vinegar ; Bently, W.E.; Edwards, G.H.; Vakharia, Kumar, G. Production Using a Noncommercial V.N.: Chimeric Infectious Bursal ; Smith, P.J.; Payne, G.I Enzymatic 100-Litre Bubble Column Reactor Disease Virus-Like Particles Expressed Grafting of a Natural Product onto Equipped with a Novel Type of in Insect Cells and Purified by Chitosan to Confer Water Solubility Dynamic Sparger, 141 Immobilized Metal Affinity Under Basic Conditions, 154 Fujikawa, S. See Higashiyama, K., 442 Chromatography, 721 Kwok, K.E. See Dowd, J.E., 484 Fussenegger, M. See Kaufmann, H., 573 Huang, P.Y. ; Carbonell, R.G.: Affinity Labrou, N.E. Ganzeveld, K.J. See Sipkema, E.M., 56 Chromatographic Screening of Soluble ; Eliopoulos, E.; Clonis, Y.D.: Molecular Gervais, C. See Mercille, S., 516 Combinatorial Peptide Libraries, 633 Modeling for the Design of a Giordano, R.C. See Araujo, M.L.G.C., 593 Hubert, P. See Oerther, S., 206 Biomimetic Chimeric Ligand Gladden, S.G. See Saarinen, M.A., 612 Application to the Purification of Goetheer, E. See Marchal, L.M., 344 Infante, M.R. See Clapés, P., 333 Bovine Heart L-Lactate Dehydrogenase Grage, H. See Palmqvist, E., 46 Ingle, J.D., Jr. See Stuart, S.L., 69 299 Green, N.H. See Hooker, A.D., 559 Iyer, M.S. Langer, R. See Ameer, G.A., 618 Gschaedler, A. ; Wiesner, T.F; Rhinehart, R.R Dynamic Lapicque, F. See Oerther, S., 206 ; Robas, N.: Boudrant, J.; Branlant, C Reoptimization of a Fed-Batch Lapicque, F. See Oerther, S., 206 Effects of Pulse Addition of Carbon Fermentor, 10 Lazarova, Z. Sources On Continuous Cultivation of Escherichia coli Containing a James, D.C. See Hooker, A.D., 559 : Tonova, K Integrated Reversed Recombinant E. coli gapA Gene, 71 Janssen, D.B. See Sipkema, E.M., 56 Micellar Extraction and Stripping of Guarna, M.M. See Fann, C.H., 464 Jaouen, P. See Vandanjon, L., | a-Amylase, 583 Guéguen, J. See Michon, T., 449 Jardin, B. See Zeiser, A.. 122 Le Doux, J.M. ; Davis, H.E.; Morgan, J.R.; Yarmush, Jenkins, N. See Hooker, A.D., 559 Hahn-Hiagerdal, B. See Palmqvist, E., 46 Jensen, N.B.S. M.L.: Kinetics of Retrovirus Production Halling, P.J. See Erbeldinger, M., 316 : Jokumsen, K.V.; Villadsen, J and Decay, 654 Harmon, W. See Ameer, G.A., 618 Determination of the Phosphorylated Le Gall, H. See Oerther, S., 206 Haynes, C.A. See Zandstra, P.W., 493 Sugars of the Embden-Meyerhoff-Parnas Lemmon, T.L. See Stuart, S.L., 69 Hellendoorn, L. Pathway in Lactococcus lactis Using a Lendenmann, U. See Smets, B.F., 642 ; Ottengraf, S.P.P.; van den Heuvel, J.C Fast Sampling Technique and Solid Lin, H.-K. See Chou, C.P., 263 Pennings, J.A.M.M.; dos Santos, Phase Extraction, 356 Lin, M.-I. See Chou, C.P., 263 V.A.P.M.; Wijffels, R.H Kinetics and Jervis, E. See Zandstra, P.W., 493 Litster, J.D. See Stuart, D.M., 383 Performance of a Co-Immobilised Jin, Y.B. See Park, J.K., 116 Liu, M. See Muzzio, F.J., 185 System of Amyloglucosidase and Johns, M.R. See Stuart, D.M., 383 Livingston, A.G. See Doig, S.D., 601 Zymomonas mobilis, 694 Jokumsen, K.V. See Jensen, N.B.S., 356 Lobo, R. Heller, M.C. Jolicoeur, M. : Revah, S.; Viveros-Garcia, T.: An ; Carpenter, J.F.; Randolph, T.W Protein ; Williams, R.D.; Chavarie, C.; Fortin Analysis of a Trickle-Bed Bioreactor Formulation and Lyophilization Cycle J.A.; Archambault, J Production of Carbon Disulfide Removal, 98 Design: Prevention of Damage Due to Glomus intraradices Propagules, an Lopez-Ulibarri, R. See Mayer, A.F., 373 Freeze-Concentration Induced Phase Arbuscular Mycorrhizal Fungus, in an Lortie, R. See Pepin, P., 502 Separation, 166 Airlift Bioreactor, 224 Lépez-Lopez, A. Hellmuth, K. See Mayer, A.F., 373 Jolicoeur, P. See Mercille, S.. 516 ; Exposito, E.; Anton, J.; Hewitt, C.J. Jérdening, H.-J. See Dols, M., 308 Rodriguez-Valera, F.; Aldaz, A Use of ; Nebe-Von Caron, G.; Nienow, A.W.; Joseph, R. See Agrawal, R., 249 Thiobacillus ferrooxidans in a Coupled AUTHOR INDEX Organophosphate Nerve Agents by Furtural, and p-Hydroxybenzoie Acid on Immobilized Eschert i coli with Growth and Ethanol Productivity of Surtace-Expresse¢ rganophosphoru Yeast 16 Macaskie, L.I Hydrolase Paquette, D. Se \ Mi Marchal, L.M. Munoz-Guerra, S. Sec Park, J.K. 06 lin, Y.B.: Chans Murakami, K. See Hi siosorbents in Capsules from Zo. Murhammer, D.W. S ramigere | Cadmium Remo 6] 116 Mutharasan, R. S« Payan, E. See Oerther, S., 206 Muzzio, F.J. Payne, G.F. See Kumar, G Massie, B. S Unger, D.R.; Liu, M Pennings, J.A.M.M. See Hellendoorn, | See Mer 1: Fahnestock, P 6904 Mateus, D.M.R. tational and Experimenta Pepin, P. M.M.R 1 of Flow and Particl Lortie, R.: Influence of Water Activity Biot on the Enantioselective Esterification of RS) Ibuprok n by Cand I IPase B in Solventh Nebe-Von Caron, G. Sci Pérez, F. See Acuna, M.I Matheson, N.H. See Noronha, S.B., 285 Neemann, J.J. Sce Erga Pérez-Camero, G. Matsumoto, N. See Higashiyan Netter, P. See Oerther, S Congregado, F.; Bou, JJ Mayer, A.F. Ni, X. See Erbeldinger, M Munoz-Guerra, S.: Biosynthesis and Hellmuth, K.: Schlieker, H Nielsen, J. See Christians« Ultrasonic Degradationo f Bacterial nez-Ulibarri, R.; Oert Nienow, A.W. Sex Poly(y-Glutamic Acid) St r, A.W.M Nieto, J. Sce Fri Piret, J.M. See Dowd, J.1 \.P.G.M.: An Expre Noronha, S.B. See Fann, C.H., 464 \ Mi Wavm See Zandstra, P.W lor Phytas« Shiloa ce « Ethanol Sensor Presle, N. See Oerther, S ol Growth and mbinant Strain Quemeneur, F. S Mazur, X. See Kau Raghavan, S. See Ameer, G.A., 618 McFarlane, C.M. Randolph, T.W. See Heller, M4 lO Meinander, N.Q. Reimer, J.A. See Ru, M.T., 233 Menon, M.K. Remaud-Simeon, M. See Dol Revah, S. See Acuna, M.E., 175 En See Lobo, R.. 9S M Oertel, S. S Rhinehart, R.R. Scx Mercille, S. Oecerther, S. Rice, K.FE. Jol r, P Watkin M D.D t Menhac Ly Dependent Nutrient-Limit Hollow-Fiber Reactor M ma i Cel Tran Robas, N. See Gschaedler, A EIB-I9K Adenovira I chanism Robert, J.M. See Vandanjon Massie, B.: Apoptosis-Resistant Okkerse, M. See Okket Robinson, A.S. See Fovucl 1 B-19K-Expressing NS/O Myeloma Okkerse, W.J.H. Robinson, C.R. See Foguc! Cells Exhibit Incre: ed Viability and Ottengrat, S.P.P.; Osin Kuipers, B Rodriguez, B. Sce Dowd, J.1 Chimeric Antibody Productivity undet Okkerse, M.: Bioma Accumulation Rodriguez-Valera, F. See Loy Pertusion Culture Conditions, 529 ind Clogging in Biotrickling Filters for \) Michon, T. Waste Gas Treatment. Evaluation of Rossignol, N. See Vandanjon, | Wane, W IT: I CGueguen Dynamic Model Using Dichloromethar Ru, M.T. Wheat Prola rossiinking Throu t Model Pollutant, 41% Dordick, J.S.; Reimer, J.A.; Clark, D.S Dityrosine rmation Catalyzedb y Osinga-Kuipers, B. See Okkerse. W.J.H Optimizing the Salt-Induced Activation Peroxida Improvement in the +1 of Enzymes in Organic Solvents: Effect Modificationo f a Poorly Accessibk Osterhout, J.J. See Knubovets, 1 of Lyophilization Time and Water Substrate by “Indirect” Catalysis, 449 Ottengraf, S.P.P. See Hellendoorn, | Content Misawa, N. See Verdoes, J. SO See Okker W.J.H., 418 Rubio-Fernandez, H. Sce Fregapane, G Mitchell, D.A. See Stuart, D.M., 383 Mitchell-Logean, C.M. See Saarinen, M.A Palazzi, EF. 612 Convert, A.: Generalized Linearization Saarinen, M.A. Monsan, P. See Bousquet, M.-P # Kinetics of Glucose Isomerization to Troutner, K.A.; Gladden, S.G See Dols, M., 308 Fructose by Immobilized Glucos« Mitchell-Logean, C.M.: Murhammet Moran, C. See Clapés, P., 333 Isomerase, 273 D.W.: Recombinant Protein Synthesis in Morgan, J.R. See Le Doux, J.M., 654 Palmqvist, E. Trichoplusia ni BTI-Tn-S5BI1-4 Insect Mosser, D.D. See Mercille, S.. 516 Grage, H.; Meinander, N.Q Cell Aggregates, 612 Mulchandani, A. Hahn-Hiigerdal, B.: Main and Salvador, M.D. See Fregapane, G., 141 Kaneva, |.; Chen, W Detoxification of Interaction Effects of Acetic Acid San, K.-Y. See Aristidou, A.A AUTHOR INDEX Sasisekharan, R. See Ameer, G.A., 618 Variables Affect Performance through and Characterization of the Astaxanthin Sasvari, Z. Their Effects on Transport Phenomena, Biosynthetic Gene Encoding Phytoene ; Asboth, B Crosslinking of 383 Desaturase of Xanthophyllomyces Glucoamylases via Carbohydrates Stuart, S.L. dendrorhous, 750 Hardly Affects Catalysis but Impairs ; Woods, S.L.; Lemmon, T.L.; Ingle, J.D., Villadsen, J. See Jensen, N.B.S., 356 Stability, 459 Jr.: The Effect of Redox Potential Viveros-Garcia, T. See Lobo, R., 98 Schimmelpennink, E.B. See Marchal, Changes on Reductive Dechlorination of Vogel, J.H. L.M., 344 Pentachlorophenol and the Degradation ; Kroner, K.-H Controlled Shear Schlieker, H. See Mayer, A.F., 3 >4 of Acetate by a Mixed, Methanogenic Filtration: A Novel Technique for Schreyer, H.B. Culture, 69 Animal Cell Separation, 663 —; Coughlin, R.W.: Effects of Stratification Stuckey, D.C. See Doig, S.D., 601 Voyer, R. See Zeiser, A., 122 in a Fluidized Bed Bioreactor During Vunjak-Novakovic, G. See Obradovic, B 197 Treatment of Metalworking Wastewater, Tatiraju, S. 129 ; Soroush, M.; Mutharasan, R Searles, J. See Muzzio, F.J., 185 Multi-Rate Nonlinear State and Wagner, L.W. See Noronha, S.B., 285 Sekelsky, A.M. Parameter Estimation in a Bioreactor, 22 Wang, D.L.C. See Follstad, B.D., 675 ; Shreve, G.S.: Kinetic Model of Thoma, M. See Beuse, M., 410 Wang, W. See Michon, T., 449 Biosurfactant-Enhanced Hexadecane Thornhill, N.F. See Yeung, K.S.Y., 684 Watkins, J. See Rice, K.E., 33 Biodegradation by Pseudomonas Tom, R. See Zeiser, A., 122 Weber, I. See Dowd, J.E., 484 aeruginosa, 401 Tonova, K. See Lazarova, Z., 583 Wiesner, T.F See lyer, M.S., 10 Shiloach, J. See Noronha, S.B., 285 Tramper, J. See Marchal, L.M., 344 Wijffels, R.H. See Hellendoorn, L., 694 Shreve, G.S. See Sekelsky, A.M., 401 Troutner, K.A. See Saarinen, M.A., 612 Willemot, R.-M. See Bousquet, M.-P., 730 Shuler, M.L. See Donaldson, M., 255 Tseng, J.-H. See Chou, C.P., 263 : See Dols, M., 308 Shumway, L. See Ergas, S.J., 431 Tsoka, S. Williams, R.D. See Jolicoeur, M., 224 Silva, J.L. See Foguel, D., 552 ; Holwill, 1.; Hoare, M.: Virus-Like Williams, T. See Yeung, K.S.Y., 684 Sipkema, E.M. Particle Analysis in Yeast Homogenate Wood, H.A. See Donaldson, M., 255 ; de Koning, W.; Van Hylckama Vlieg, Using a Laser Light-Scattering Assay, Woods, S.L. See Stuart, S.L., 69 J.E.T.; Ganzeveld, K.J.; Janssen, D.B.; 290 Beenackers, A.A.C.M.: Trichloroethene Tsujimura, H. See Higashiyama, K., 442 Yarmush, M.L. See Le Doux, J.M., 654 Degradation in a Two-Step System by Yeung, K.S.Y. Methylosinus trichosporium OB3b Unger, D.R. See Muzzio, F.J., 185 ; Hoare, M.; Thornhill, N.F.; Williams Optimization of System Performance T.; Vaghyiani, J.D.: Near-Infrared Use of Formate and Methane, 56 Vaghijiani, J.D. See Yeung, K.S.Y., 684 Spectroscopy for Bioprocess Monitoring Smets, B.F. Vakharia, V.N. See Hu, Y.-C., 721 and Control, 684 ; Fiefler, R.G.; Lendenmann, U.; Spain, van de Laar, A.M.J. See Marchal, L.M.., Yu, C.-C. See Chou, C.P., 263 J.C.: Kinetic Analysis of Simultaneous 344 2,4-Dinitrotoluene (DNT) and 2,6-DNT van den Heuvel, J.C. See Hellendoorn, L., Zandstra, P.W. Biodegradation in an Aerobic 694 ; Jervis, E.; Haynes, C.A.; Kilburn, D.G Fluidized-Bed Biofilm Reactor, 642 Van Hylickama Vlieg, J.E.T. See Sipkema, Eaves, C.J.; Piret, J.M Smith, P.J. See Kumar, G., 154 E.M., 56 Concentration-Dependent Internalizatior Soroush, M. See Tatiraju, S., 22 van Loon, A.P.G.M. See Mayer, A.F., 373 of a Cytokine/Cytokine Receptor Spain, J.C. See Smets, B.F., 642 van Ooyen, A.J.J. See Verdoes, J.C., 750 Complex in Human Hematopoietic Spohr, A.B. See Christiansen, T., 147 Vandanjon, L. Cells, 493 Stephanopoulos, G. See Follstad, B.D., 675 ; Rossignol, N.; Jaouen, P.; Robert, J.M.; Zeiser, A. Strange, P.G. See Hooker, A.D., 559 Quémeéneur, F.: Effects of Shear on ; Bédard, C.; Voyer, R.; Jardin, B.; Tom Strasser, A.W.M. See Mayer, A.F., 373 Two Microalgae Species. Contribution R.; Kamen, A.A.: On-Line Monitoring Stuart, D.M. of Pumps and Valves in Tangential of the Progress of Infection in Sf-9 -; Mitchell, D.A.; Johns, M.R.; Litster, Flow Filtration Systems, | Insect Cell Cultures Using Relative J.D.: Solid-State Fermentation in Verdoes, J.C. Permittivity Measurements, 122 Rotating Drum Bioreactors: Operating ; Misawa, N.; van Ooyen, A.J.J.: Cloning Zydney, A.L. See Menon, M.K., 298 AUTHOR INDEX Biotechnology and Bioengineering Subject Index to Volume 63 Acceptor reaction, 308 ‘entral metabolism, 675 Ethanol, 285 Acetic acid fermentation | Cephalosporin C production, 593 Ethanolic fermentation, 46 Activated sludge ‘hemostat culture, 675 xpansion, 473 ADH2, 285 ‘hitosan, 154 :xperimental design, 46 Affinity chromato ‘hlorogenic ac id, 154 xpression, 392 Affinity ligand, 63 HO cells, 559 xpression system, 373 Agarose bioreactor, 618 ‘hondrocyte metabolism, 197 =xtraction method, 356 Aggregates, 473 ‘ircular dichroism (CD), 242 Air pollution control, 418 itrobacter, 87 Fed-batch, 705 Albumin, 298 ‘o-immobilised systems, 694 Fed-batch fermentor, 10 ALS ‘odigestion, 363 Fermentation development, 373 AM fungi, 224 ‘ombinatorial libraries, 633 Ferrous iron oxidation, 79 Amino acid-based surtactants omplementation, 750 Flourescence-assisted carbohydrate Ammonia ‘ontinuous culture, 410 electrophoresis, 255 amylase ontinuous fermentation, 712 Flow cytometry, 705 iAeM M Yi| OLriu ontrolled shear filtration, 663 Fluidized bed, 618 Anaerobic ARANRRRAA ‘RRAo oRAli ng rate, 166 Apoptosis 529 ‘ovalent enzyme oligomers, 459 gapA gene, 712 Arachidonic acid ‘rossflow. 663 GAPDH, 712 j sper is, 2A4 9 ‘rosslinking, 449, 459 Gel-immobilised cells, 625 As ner 4S RrK ‘ulRture conditions, 255 Gene dosage, 464 ~ ‘ytokine depletion, 493 Gene expression, 263 Gene therapy, 654 Bac Baculo, virus Daucus carota, 224 Genetic manipulation, 263 Glomus intraradices, 224 Baculovirus expression vector Dextransucrase, 308 Glucoamylase, 459 BHK, 464 Dichloromethane, 418 Glucose isomerase, 273 Biochemical 1 Diffusion, 625 Glucose isomerization, 273 Biodegradation Diffusion phenomena, 206 B-glucosidase, 392 Biofilm, 87, 175 Discrete modes of oscillation, 410 Biofilter ) Dissolved oxygen, 255, 442 Glycolysis, 356 Glycosylation, 255 Biofiltration, 418 Dityrosine, 449 Growth conditions, 473 Biogas reactors, 363 DNA shuffling, 544 Growth kinetics, 147 Biological treatment, 431 Downstream processes, 5% Biological trickling filters + Dynamic light scattering, Hairy roots, 224 Biomimetic dye Dynamic model, 418 Bioprocess Dynamic modelling, 694 Hansenula polymorpha 3 2 Heat shock, 516 Biopro Dynamic re-optimization Hematopoietic cells, 493 Bioreactor Dynamic sparger, 141 Heparin neutralization, 618 Bioreactors Heparinase, 618 Bioseparation, 583 1B-19K, 529, 516 Heterologous expression, 750 Biosorption, 116 392, Hexadecane, 401 Biosurfactant, 401] ffectiveness factor, 593 High cell density, 705 Biphenyl! dioxygenase, 544 icosapentaenoic (EPA) and High cell-density cultivation, 373 Blood detoxification, 618 docosahexaenoic (DHA) acid residues, 33 Hollow-fiber bioreactors, 484 Bubble column reactor, 141 lectrochemical reactor, 79 Hollow fiber membranes, 431 am butylglucoside, 730 lectrochemical wastewater treatment, 79 Hollow-fiber reactor, 33 lectrostatic interactions, 298 HPAE-PAD, 356 xygen diffusivity MP pathway, 356 Human secreted alkaline phosphatase, 255 nantioselectivity, 502 Hybridoma, 529, 516 ndomycorrhizae, 224 Hydrolysis, 33 andida nvironment, 255 Hydrostatic pressure, 552 ( apacitance nzymatic, 316 ( apsule, 116 nzymatic amide and ester bond formation, Ibuprofen, 502 ( arbohydrates, 363 333 Immobilized cells, 87, 593 ( arbon disulfide removal QR nzyme, 154 Immobilized lipase, 33 ( arotenoid, 750 nzyme activation, 233 Immobilized metal affinity chromatography K Carrageenan nzyme inactivation, 273 (IMAC), 721 ( artilage, 19 nzyme purification, 322, 583 Inclusion body, 552 ( DNA copy number, 464 nzymes deposited onto supports, 333 Indole, 625 ( ell aggregates, 612 poxidation, 601 Inducible expression, 516 ( ell culture, 516, 663, 67 5 scherichia coli, 263 Infectious bursal disease virus (IBDV), 72 ( ‘ell cycle, 410 scherichia coli, 705, 73 Inhibitors, 46 ( ell separation, 663 sterification, 502, 730 Inoculation conditions, 473 Biotechnology and Bioengineering, Vol. 63, Pp. 764-765 (1999) Insect, 255 Organic solvents, 233, 242, 449 Shear effects, | Insect cells, 122, 559, 612 Oxygen, 197 Shear stress, 663 Interaction effects, 46 Simulation, 363 Interferon, 559 P22 tailspike, 552 Single hyphae, 147 lon binding, 298 Papain, 333 Size-exclusion HPLC, 552 Parameter estimation, 22 Sodium alginate, 206 Kinetic model, 308, 401 Particle settling, 185 Sodium butyrate, 464 Kinetics, 69, 273 » Penicillin acylase, 263 Sodium hyaluronate, 206 Penicillium, 249 Solid phase extraction, 356 L-serine, 625 Pentachlorophenol, 69 Solid-state fermentation, 383 L-tryptophan, 625 Peptide, 633 Solid-to-solid conversion, 316 Lactate dehy drogenase, 322 Peptide synthesis, 316 Soluble peptide library, 633 Lactococcus lactis, 356 Perfusion, 484, 529 Sorghum, 392 Ligand design, 322 Permittivity, 122 Spores, 224 Lipase, 233, 502, 730 Peroxidase, 449 Spray freeze drying, 166 Lipids, 363 Pesticides, 216 Stability, 694 Low-cost protein produc22t ion, 373 PET21, 392 Staggered extension process, 544 Lyophilization, 166, 233 PH regulation, 507 State estimation, 22 Lysozyme, 242 Phase separation, 166 Structure, tertiary and secondary, : ~ S1L9 Phosphatase, 87 Subsite map, 344 Maize, 392 Phosphorus removal, 507 Substrate protection, 273 Malaria, 285 PLS, 684 Subtilisin Carlsberg, 233 Maltose, 308 Poly(y-glutamic acid) (PGGA), 110 Suspension bioreactor, 47 Mammalian cells, 675 Polychlorinated biphenyls (PCBs), 544 Sustained oscillation, 410 Mammalian neural stem cells, 473 Polymer modification, 154 Mass spectrometry, 559 Predictive control, 484 Tangential flow filtration Mathematical model, 363 Process monitoring, 22 Taylor-Couette flow, 618 Membrane bioreactor, 601 Process—model mismatch, 10 TBV25H, 285 Membrane integrity, 705 Product specificity, 344 emperature, 255, 344 Membrane potential, 705 Propagules, 224 Thermostability, 459 Menhaden oil, 33 Proteases, 316 Thiobacillus ferrooxidans Metabolic flux, 675 Protein aggregation, 552 Time of harvest, Metabolic flux analysis, 737 Protein extraction, 583 issue engineering, 197 Metabolic model, 507 Protein folding, 552 Toluene biodegradation, 175 Metal accumulation, 87 Protein purification, 721 rransduction efficiency, 654 Methylosinus trichosporium OB3b, 56 Protein separations, 298 Transformation capacity, 56 Microalgae, | Protein stability, 166 Transglycosylation, 344 Microcosms, 175 Proteins, 363 Transport phenomena, 383 Microfiltration, 663 Proteins dissolved in nonaqueous solvents, Triazine dye, 322 Mixing, 185 47 Trichloroethene, 56 Model, 98 Pseudomonas oleovorans, 601 rickle-bed bioreactor, 98 Model re-parametrization, 10 Pumps, | Irypsin, 333 Modeling, 431 I'wo-step bioreactor system, 56 Molecular modeling, 322 Random mutagenesis, 544 Tyrosinase, 154 Molecular weight distribution, 344 Rapid monitoring, 290 Monitoring, 684 Rate controlling step, 98 Ultrafiltration, 298, 721 Monoclonal antibodies, 484, 529 Reaction-diffusion model, 593 Ultrasonic degradation, 110 Monte Carlo simulation, 147 Real-time implementation, 22 Unsaturated fatty acid, 730 Morphology, 147, 442 Receptor internalization, 493 Uptake mechanism, 40] Recombinant DNA, 712 Mortierella alpina, 44? MRNA level, 464 Recombinant DNA technology, 263 Valves, | Multi-rate measurements, 22 Recombinant protein production, 464 Verbenol, 249 Mutant, 249 Recombinant retroviruses, 654 Vesicles, 224 Viability, 705 Myeloma, 529, 516 Redox potential, 69 Reductive dechlorination, 69 Virus decay, 654 N-glycosylation, 559 Resolution, 502 Virus-like particle, 290 Virus-like particles (VLP), 72 NAPL reduction, 401 Retransfection, 464 Virus production, 654 NIR spectroscopy, 684 Reversed micelles, 583 Non-conventional media, 730 Rheological measurements, 206 Virus titer, 654 Nuclear magnetic resonance (NMR), 242 Roller bottles, 185 Volatile organic compounds, 431 Nucleotide sugars, 559 Rotating drum bioreactor, 383 Waste gas treatment, 418 Water activity, 502 Oat, 392 Saccharide composition, 344 Wheat prolamines, 449 1,7-octadiene, 601 Saccharomyces, 285 Wine vinegar production, 14] Oligosaccharide, 308 Saccharomyces cerevisiae, 410 On-line monitoring, 122 Salts, 233 Yeast, 46, 750 OPH, 216 Secretion, 464, 559 Optimizing protein secretion, 373 SEM, 175 Zoogloea ramigera, 116 Organic media, 333 Sensor, 285 Zymomonas mobilis, 694 SUBJECT INDEX ‘ ‘ - 2 i: . ae poe eS i a 2 ri

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