Biopolymers 1993: Vol 33 Index

25 Pages·1993·7.6 MB·English

BIOPOLYMERS
ORIGINAL RESEARCH ON BIOMOLECULES
Volume 33 e 1993
EDITOR
Murray Goodman, Department of Chemistry, University of California, San Diego, La Jolla, California 92093
EDITORIAL BOARD
Kenneth J. Breslauer, Department of Chemistry, Rutgers University, Piscataway, New Jersey, 08855-0939
C. Allen Bush, Department of Chemistry and Biochemistry, University of Maryland, Baltimore, Maryland 21228
David A. Case, Department of Molecular Biology, MB2, Research Institute of Scripps Clinic, La Jolla, California 92037
Charles M. Deber, Biochemistry Department, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
Ken A. Dill, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco,
California 94143
Paul J. Hagerman, Departments of Biochemistry, Biophysics and Genetics, University of Colorado Medical Center,
Denver, Colorado 80262
David R. Kearns, Department of Chemistry, University of California, San Diego, La Jolla, California 93093
David E. Wemmer, Department of Chemistry, University of California, Berkeley, California 94720
FOUNDING EDITORS
Elkan Blout, Harvard Medical School, Boston, Massachusetts 02115
Ephraim (Katchalski) Katzir, The Weizmann Institute of Science, Rehovot, Israel
ADVISORY BOARD
E. D. T. Atkins L. Gierasch W. L. Mattice J. Schellman
R. L. Baldwin A. Hagler J. A. McCammon H. A. Scheraga
E. Benedetti W. C. Johnson T. Miyazawa P. Schiller
D. L. Beveridge R. Kaptein L. Moroder J. D. Simon
V. Bloomfield I. L. Karle F. Naider A. Stone
J.S. Cohen M. Karplus W. Olson I. Tinoco
D. M. Crothers H. Kessler E. Peggion G. J. Thomas, Jr.
D. Eisenberg P. Kollman M. T. Record, Jr. G. Van Binst
E. L. Elson S. Krimm G. Rose K. Wiithrich
G. Fasman I. Kuntz, Jr. S. Sakakibara B. H. Zimm
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Biopolymers
Subject Index to Volume 33
A dehydropeptide, 1111 Amylose, crystallographic Base tilt, 245
Ab initio, 1591 studies, 363 16 Base-pair (CG), sequence,
Absorption spectra, Amylose, molecular mechanics 1725
photoinduction of DNA- calculation with B-DNA structural analysis, 12-
protein cross-linking constraints, 363 and 14mers containing
measured by, 239 Amylose, starch-iodine GAATTC, 459
Acetylcholine, 961 complex, 363 B-DNA structural analysis, by
Acetylcholine receptor, 961 A-NaDNA, 633 molecular dynamics
Adenine binding study of, the Analogous, 1073 simulations, 459
ricin A-chain by Analogues, 1037, 1149 B-DNA structural analysis,
spectroscopy, 1687 Analysis, of SEC elution structural predictions of,
Aggregation in solution, 521 profiles for the 459
Aib, helical peptide containing, ribonuclease G-alanine, 621
995 conformational transition B-strand segment, 1271
Aib peptide, 401 in guanidine @-turn, 665
Aib-containing peptide, 1337 hydrochloride, 135 8-turn conformation, formed
Alanine-based peptides Anion binding, detected by by (aMe)Phe homo-
sequence dependence of NMR, 1709 peptides, 1617
a-helical stability, 971 Anionic melittin analogs, 305 Beta-turns, 201
Alginate aqueous solution, Antiamoebin, 401 Binding of adenine, ricin A-
chain with, at acidic pH,
Ca(II), Cu(II), Co(II), Antifreeze molecules, 1481
1687
Mn(II), cross-link Antifreeze polypeptides, 1481
Bioactive peptides, 1083
formation, 703 Antlion method, 293
Biologically active peptides,
Alkyl-linked DNAs, 1765 Apolar oligopeptide, 1337
1073
a-amino acids, 1061 Application to loops in bpti,
Biophysical scales, 293
a-aminoisobutyric acid 1271
Blood substitutes, 1803
peptides, 865 Ascomycin, 535
Bovine serum albumin,
a-aminoisobutyric acid, use in Assignments, 535
influence of hydration on
synthetic peptide helix Asymmetric synthesis, 1073
conformation of, 1871
models, 389 Atomic flexibility, 735
Bovine serum albumin, solid
a-carbon, 1061 Atomic friction coefficients,
state °C NMR
a-helical segment, 1271 methods for calculation of,
spectroscopy of, 1871
a-helix, 255, 1195, 1337 1423
Bradykinin agonists and
Alpha helices, 1481 Auto-cooperative binding,
antagonists, 769
AMBER 3a program, 1811 complex formation, 703
Bradykinin analogs, 769
Amide bonds, 1135 Azapeptides, 1051
Bradykinin antagonists, 1237
Amino acid aggregation, 283 AzaProline residue, 1051
Branched chain polypeptides,
Amino acid conformation, 283
873
Amino acid-succinate B—A transition in DNA, 37 Brownian dynamics, 1519
interactions, 283 Backbone conformation, 1093 Building blocks, 1037
Amino group analysis, Backbone, virtual bond
Bulged cytosine, in a
detection of amino modeling of, 329
deoxyribooligonucleotide,
derivatised polysialic acid Backbone/side chain 27
by, 453 interaction, 665
AMP, 1791 Base pair, 351 8C spectra, 1365
Amphiphilicity, 1195 Base pairs, 797 Ca?* titrations, 497
Biopolymers, Vol. 33, 1911-1920 (1993)
1912 SUBJECT INDEX
Calcium, effect of in promoting Circular dichroism studies, of Conformational constraints,
laminin aggregation, 475 synthetic peptide helix 1135
Calculation and determination models, 389 Conformational energy
of dipole moment of Circular dichroism studies, of computations, 1061
proteins, 59 uteroglobin fragments, Conformational energy
Canonical A form and Z form, 1877 minimization, 329
1715 Circular dichroism study, of Conformational mobility, 1093
Capillary gel electrophoresis, of poly(L-Glu), 1299 Conformational search, by
poly(L-Glu), 1299 Cis Phe peptide bond, 693 dynamic programming, 173
Capillary gei electrophoresis, Cisplatin, 1631 Conformational similarity
split peaks, 1299 cis-trans isomerism, 915 between Aib and Iva
Carbonic anhydrase hydrolase Cis—trans isomerization, 781, peptides, 1207
activity, C,N, as selective 933 Conformational space, 1003
probe for, 687 C*-Methyl phenylalanine, Conformational studies, 305
Carboplatin, 1631 homo-peptides from, 1617 Conformational transitions,
Cardiotoxin, snake venom CMP, 1791 497, 903
protein; cytolytic activity, Coil-helix transitions, 985 Continuum models, 1851
1659 Collagen, peptide of, 521
Convergence temperatures,
Catechin, 275 Combinatory map, 1389 denaturation entropy and
Cationic drugs, 1415
Comparison of flexibility of enthalpy, 1185
CD spectra, 1111
collagen type I and type Correlation functions, 1519
CD spectroscopy, 1415 IV, 897 Correlation length, 1389
CD studies, 1019
Complexation, 305 Correlation matrix, 1605
Chain stiffness, 561
Compressibility, 11 COSY, correlated
CHARMM force field, 1843
Computer simulation, 329 spectroscopy, 1659
Chemical evolution, 283
Computer simulations, 903 Counterion concentration, 1029
Chemotactic peptide analog,
Computer-aided modelling, of Counterions, 1537
synthesis, conformation,
peptides and the Coupling constant, 275
and activity of, 437
interaction between Coupling constants, 1003
Chiral discrimination, 933, 1377
peptide and t-Boc- Coupling constants, averaged
Chloroquine/quinacrine
binding to DNA, 887 aminoacids, 933 values found by MD, 575
Concerted helix motions, 735
Circular dichroism, 497, 665, Coupling constants, values for
Condensation, 1819
927, 1195, 1779 chair, boat, and twist boat
Circular dichroism, calculated, Conformation, 75, 275, 401, forms, 575
of A*Phe-peptides, 1173 479, 665, 961, 1591 Cross polarization magic-angle
Circular dichroism, of Conformation of deoxyribose spinning °C NMR
dehydropeptides, 1 in polynucleotides, sugar spectroscopy of bovine
Circular dichroism, of nucleic ring flexibility in the serum albumin, 1871
acids, 315 process of, 37 Cross polarization magic-angle
Circular dichroism, of Conformation of D/L-Iva-L-pro spinning “C NMR
photochromic sequence, 1207 spectroscopy of lysozyme,
polypeptides, 1505 Conformation of tachykinin 513
Circular dichroism studies, in peptides, 1901 Crystal state conformation,
trifluorethanol/water Conformational analysis, 971, 1051
mixtures, 389 1101 Crystal structure, 275, 335, 401,
Circular dichroism studies, of Conformational analysis, by 1337
collagen-model peptides, 'H-NMR, IR and circular Crystal structure analysis,
1695 dichroism studies, 1173 molecular conformation of
Circular dichroism studies, of Conformational analysis, of Dnp-(L/pD)-Val-Aib-Gly-
partially hydrolyzed polypeptides, 173 Leu-pNA by X-ray single
xanthan, 151 Conformational changes, 827 crystal analysis of
Circular dichroism studies, of Conformational tetrapeptide containing
poly(L-Lys), 1553 considerations, 1073 Aib residue, 813
SUBJECT INDEX 1913
Crystal structure Dehydrophenylalanine calorimetry (DSC), of
determination, 1207 containing peptides, 209 partially hydrolyzed
Crystal structure, of Dehydrophenylalanine, xanthan, 151
didehydrophenylalanine peptides containing, 1 Diffusion-collision model, 1519
pentapeptide, 209 Dehydrophenylalanine- Dinucleotide monophosphates,
Crystal structures, 1101 possessing peptides, 75
Curved DNA, 639 conformations, 1173 Dipole moment calculation for
Cyanogen, ethanedinitrile, salt 6-opioid receptor, bioactive the various deoxyribose
bridge conversion to structure, 647 puckered states, 37
covalent links in carbonic Denaturation, 797, 1819 Dipole moment of small
anhydrase, 687 Denaturation thermodynamics, proteins, 59
Cyclic enkephalins, computer hydrophobicity and, for Discrimination from a-helix,
assisted conformational model proteins, 1185 995
analysis, 647 Denaturation to renaturation, Disulfide bridge, 1591
Cyclic enkephalins, structure 193 Disulfide bridged peptides, 865
Deoxyadenosine, molecular DNA, 75, 147, 377, 797, 1537,
activity relationship, 647
Cyclic oligopeptides, 1093 dynamics simulations on, 1725, 1819
Cyclic peptide, 933 1167 DNA bases, 1851
Deoxyadenosine, molecular DNA chain overstretching,
Cyclic peptide flexibility,
modeling of, 1167 during pulsed field gel
simulation analysis, 1249
Deoxyadenosine, transition electrophoresis, 1359
Cyclic peptides, 201
pathways for, 1167 DNA crystal, 1715
Cyclic peptides, cis—trans
Depolarization ratios of DNA dumbbell, and single
isomerization, 693, 1377
Raman bands, 1791 strand studied by, 1779
Cyclic pseudopentapeptides,
Dermenkephalin, 1889 DNA dumbbells, optical
1101
Design of synthetic, melting studies of, 1765
Cyclobutane ring
biodegradable carriers for DNA dumbbells, with alkyl
conformation, substituent
drug delivery, 873 end-loops, 1765
effects, 713
Design of synthetic, DNA, fluctuational opening of,
Cyclobutane ring flexibility,
biodegradable carriers for 351
substituent effects, 713 vaccine development, 873 DNA hydration, 117
Cyrosolvents, 915
Detection of interactions, DNA intercalating agents as
Cystine peptides, 865
between functional groups effective inducers of cross-
Cystiny] cycloheptapeptide, and metal ions, by °C linking, 239
1083
nuclear magnetic DNA intercalation, 887
resonance, 703 DNA, melting, 351
2D NMR, 915 Deuterium exchange of purine DNA oligonucleotides, 943
d(C,,GCG,,), 1715 C8H, 943, 943 DNA orientation, 1225
Decay of tryptophan Dextran, benzene DNA, suprahelical
fluorescence anisotropy, tetracarboxylate- organization, 1415
1423 substituted, 1803 DNA triplex, formed with a,
Deconvolution, 665 Dextran, conjugated to 1779
Deformations, 335 oxyhemoglobin, 1803 2D-NMR, proteins spectra,
Degree of polarization, of Diagonalization of large solution structure
optically anisotropic matrices, 599 determination, 1659
sphere, 69 4',6-Diamidino-2-phenylindole, 2D-NMR, two-dimensional
|
Dehydro amino acids, 209 1677 Nuclear Magnetic
Dehydro residues, 1111 Diastereomer of tetrapeptide, Resonance, analysis of,
Dehydroalanine, 1811 containing Dnp and pNA 1659
1
Dehydropeptides, chromophores, 813 Docking models, 933
|
conformation in solution Dielectric constant of protein Double helical structure of
1
of, 1 solutions, 59 amylose, central cavity,
Dehydropeptides, synthesis of, Dielectric functions, 1537 363
1 Differential scanning Double helical structure of
1914 SUBJECT INDEX
amylose, energetic Empirical model, for Global structural homologies,
stability, 363 simulation of size 1829
Double helical structure of exclusion chromatographic Globular proteins, 11
amyluse, hydrogen bonds, elution profiles, 127 GMP, 1791
363 Energetics of local region, 1271
Double helical structure of Energy, 1591 1H NMR of
amylose, left-handed- Energy minimization, 75 d(CGCGAATTCGCG),,
right-handed, 363 Energy, minimization of, 329 943
Double helical structure of Enthalpy, 753 "H NMR spectroscopy, 1237
amylose, parallel- Entropy, 753 Heat capacity, 753
stranded-antiparallel- Equilibrium model, 1643 Helical conformation, 1901
stranded, 363 Excluded volume, 491 Helical peptides,
DQF-COSY, double-quantum Extracellular matrix proteins, conformationa!]
filtered COSY, 1659 475 constrained, 1173
Drugs, 1051 Extrahelical cytosine, in an 3,9-Helices, formed by
dTMP, 1791 A:T tract, 27 (aMe)Phe homo-peptides,
Dynamic light scattering, 551, 1617
1643 Filterable aggregate (FA), 953 3,9-Helix, 401
Dynamic light scattering FK506 binding protein, 535 3,9-helix, 1337
(DLS), 409, 1747 Flexible macromolecules, 409 Helix conformation,
Dynamic light scattering, Flory—Huggins interaction stabilization by
intramolecular entropy and enthalpy in trifluoroethanol, 389
interference effects in, elastogenesis, 743 Helix conformation,
1757 Fluctuations (role of) in the stabilization in synthetic
Dynamic light scattering, of self-assembly of peptide models, 389
small rings, 1757 bioelastomeric structures Helix dipole model, 1195
Dynamics, 275 from solutions, 743 Helix formation, 491
Dynamics (MD) simulations, Fluorescence, 1431 3,9 helix, in model
1123 Fluorescence microscopy, 45 dehydropeptides, 209
Dynamics of DNA, during Fluorescence quenching, 1677 3,o-helix, observation from
pulsed field gel Fluorescence spectra, ROESY experiments, 995
electrophoresis, 1347, 1359 photodegradation of 3,9-Helix, reversal of screw
Dynamics of large proteins, 599 tryptophan characterized sense of, 1
Dynamics of water molecules by, 239 Helix screw sense, 1061
in hydrated A-DNA Fluorescent lipids, 45 Helix stability, in water and
oriented fibers, 633 Folding mechanism, 903 water-trifluoroethanol
Dynemicin-A-DNA cleavage Formation of molecular mixtures, 1159
mechanism, 377 complexes, 1377 Helix stabilization, 985
Formyltripeptide, crystal Helix structure, 335
Effective charge of DNA in structure and solution 3,9-Helix structure, presence
solution, 1347 conformation of, 437 of, in dehydropeptides, 1
Elasticity theory, 639 FTIR spectroscopy, 1819 Helix unfolding, 827
Electric birefringence study, of Fused 6y-turn, 1443 Helix—coil transition, 1029
separation of DNA in Helix-coil transitions, 971
agarose gels, 1347, 1359 y-turn, 621 Helix—coil transitions, 1519
Electron microscopy, 561 Gel permeation Hemoglobin, normal adult, 735
Electrostatic interaction of chromatography, 561 Hemoglobin, sickle, 735
sugar pucker with Generalized Langevin High-frequency dielectric
phosphate groups and equation, 1423 dispersion, 1029
counterions, 37 Geometry, 479 ‘H-nmr spectroscopy, 1061,
Electrostatics, 1537 Gibbs function, 753 1149
Elongational flow Global minimization, of Homologous proteins, 839
birefringence, 897 molecular mechanics Homo-peptides, from
Emerimicin, 401 potential functions, 173 (aMe)Phe, 1617
SUBJECT INDEX 1915
(?H,)TSP, sodium 3-trimethyl- Leu-L-Lys), poly(L-Leu-.- incompatible compounds,
silyl-(2,2’,3,3’- Leu-L-Asp), 1553 453
*H)propionate, 1659 Interaction mechanisms Local region, 1271
Human hemoglobin, 1803 between peptide and Long time peptide dynamics,
Human immunodeficiency t-Boc-aminoacids, 933 1423
virus (HIV) proteases, Intercalation, 1431 Long-range electron transfer
1405 Interference effects, in (LRET), 781
Hydration, 797 dynamic light scattering, Loop conformations, 1271
Hydrodynamic, 1225 1757 Low energy conformations,
Hydrodynamic diameter, 1643 1843
Interference effects, of small
Hydrodynamic measurements, rings, 1757 Low frequency molecular
409 Intermolecular hydrogen vibrations, 599
Hydrogen bond, 797 bonding, 933 Low oxygen affinity
Hydrogen bond rupture by conjugates, 1803
Intermolecular motions, 725
solvation, 827 Intersegment energy, 1271 Lysozyme, influence of
Hydrogen bonds, 1337 hydration on conformation
Intrasegment energy, 1271
Hydrophobic hydration, effect of, 513
Intrinsic optical anisotropy, of
of, on protein stabilities, Lysozyme, solid state *C NMR
southern bean mosaic
1185 spectroscopy of, 513
virus, 69
Inverse y-turn, 1443
Iduronate (IdoA) ring Macromolecular cyclization,
IR, 1461
conformations, 193
IR studies, on the solid state
interchange between, 575 Magnetic relaxation, off-
secondary structure, of
Iduronate (IdoA) ring resonance rotating frame
hydrophobic sequential
conformations, molecular spin-lattice, 1581
polypeptides, 1477
dynamics simulation, 575 Magnetic relaxation, rotational
Isotropic reorientational
Iduronate (IdoA) ring correlation time, 1581
motion, determination of
conformations, relative Main immunogenic region
the rotational
proportions found by (MIR) analogues, 1123
correlational time, 1581
NMR, 575 Markers modes of the
Isotropic reorientational
Immunosuppressant, 535 canonical A form, 1715
motion, of globular
Incipient formation of 8-bulge, Mean-field approximation
proteins, 1581
163 (validity of) in describing
Inclusion compound, 283 solvent-induced
Individual site-binding data, x-Carrageenan, anion binding interactions and
to, 1709
analysis of, 1327 concentration fluctuations
Infrared spectroscopy, 201 x-Carrageenan, helix-coil in solutions of
Instability, spinodal line and transition, 1709 bioelastomers, 743
critical behavior of , Melittin, 293, 491
solutions of bioelastomers, Laminin-—nidogen, 475 Melting, 797
743 Landscape, 1389 Membrane proteins, 255
Insulin, 927, 1643 Langmuir-Blodgett films, 45 Mesh size of agarose gels, 1347
Integrated optics studies, of Lattice, modeling the dynamics Metal ions, 1819
protein binding at a lipid of, 329 Methylated polypeptides, 491
membrane surface, 475 Lattice vibrations, 725 Metropolis sampling, in Monte
Interaction, 1431 Lifson-Roig theory, 1605 Carlo simulation, 1307
Interaction between peptide Light absorption, 1431 Micro FTIR, micro Raman
and t-Boc-aminoacids, Light scattering, 561 studies, 1715
933, 933 Linear aggregates, 551 Microdomains, 1519
Interaction complexes, of Linear dichroism, 245, 1225, Microwave spectrometry, 147
poly(L-Lys), 1553 1431, 1677 Mixed counterion systems, 985
Interaction complexes of, Lipid dynamics, 45 Model for methylated proteins,
poly(L-Lys), poly(D-Lys), Liposomes, potential as 305
poly(L-Glu), poly(L-Leu-.- interface between solvent Model of the motion of the
1916 SUBJECT INDEX
DNA chain, during pulsed Multisite enzymes, 1405 methylamide, influence of
field gel electrophoresis, Myasthenia gravis (MG), 1123 hydrogen bonding on the
1359 Myoglobin, immunogenic conformation of, 659
Modeling, of protein backbones peptide of, 1159 N-t-butoxycarbonylproline N’-
on lattices, 329 methylamide, infrared
Modelling, 479 N*, N‘-trimethylated melittin spectra, 659
Molar mass, 1643 (permethylated melittin), N-t-butoxycarbonylproline N’-
Molecular chains, 1829 305 methylamide,
Molecular dynamics, 201, 665, Nascent helix, 1443 thermodynamic data, 659
1537, 1567 Neural networks, 293 N-telopeptide, 1443
Molecular dynamics (MD), Neuropeptide Y, 1195 N-terminal analog peptide,
735, 1003, 1083 Neurotoxin, 961 401, 401
Molecular dynamics, of NF-M neurofilament Nuclear magnetic resonance
iduronate containing fragments, 497 line-shape studies, 1093
trisaccharide (GleNAc- N-formyl]-methiony]-(Z)-2,3- Nuclear magnetic resonance
IdoA-GleNAc), 575 didehydroleucyl- studies, of oligonucleotide
Molecular dynamics, of phenylalanine, methyl containing unpaired base,
iduronate methyl glycoside ester, 437 27
(IdoAOMe), 575 N-glycopeptides, 665 Nuclear magnetic resonance
Molecular dynamics, sampling NMR, 107, 665 studies of purine C8H
phase space by, 1307 NMR and helical peptides, 1567 exchange, 943
Molecular dynamics NMR, composite pulses, 1709 Nuclear magnetic resonance
simulation, 335, 377 NMR, logitudinal relaxation studies, of uteroglobin
Molecular dynamics time, 1709 fragments, 1877
simulation, of helix NMR of, 943 Nuclear Overhauser effect,
stability in mixed solvents, NMR spectra, 839 1901
1159 NMR spectroscopy, 1287, 1443 Nuclear Overhauser effect
Molecular dynamics studies, of NMR spectroscopy, °C restrained molecular
a series of cyclic peptide relaxation times, 575 dynamics, 1149
analogs, 1249 NMR spectroscopy, carbon Nucleic acid analysis, platinum
Molecular interactions, 1377 and proton, of peptides, drugs, using, 1631
Molecular mechanics, 769, 1591 521 Nucleic acid analysis, studies
Molecular mechanics and NMR spectroscopy, coupling of interactions with, 1631
molecular dynamics, 693 constants, 575 Nucleic acids, 479
Molecular modeling, 219, 231, nmr studies, 865 Nucleotides of RNA and DNA,
1377 NMR studies, 933 1791
Molecular recognition, 1377 NMR, transverse relaxation
Molecular surfaces, surface time, 1709 Oligomers, 1643
analysis, 219, 231 NOE, nuclear Overhauser Oligonucleotides, 335
Molecular surfaces, surface effect, 1659 Optical rotation studies, of
characterization, 219, 231 NOESY, NOE spectroscopy, partially hydrolyzed
Molecular weight distribution, 1659 xanthan, 151
561 Nonapeptide, 401 Order parameters, 1567
Monoclonal anti-MIR Nonaqueous solvents, 927 Ordinary-—extraordinary (o-e)
antibody, 1123 Nonbonded interactions, 725 transition, 953
Monte Carlo calculations, 75 Noncoded amino acids, 1811 Organic solvents, 1003
Monte Carlo chain growth Normal mode analysis, of Orientation of the DNA chain,
method, use of cyclic peptides, 1249 during electrophoretic
experimental observation Normal modes, 599 transport, 1347, 1359
in, 1843 N-t-butoxycarbonylproline N’- Orientational correlation time,
Monte Carlo simulated methylamide, complexes 1423
annealing, 1271 of, with phenol derivatives, Oriented biopolymers,
Monte Carlo simulation, 329 659 structural analysis of by
Multidimensional NMR, 535 N-t-butoxycarbonylproline N’- solid state *N NMR, 847
SUBJECT INDEX 1917
Ovalbumin, 551 Polarization effects, 1851 Polymorphonuclear leukocyte
Overshoot, 1359 PolyA: polyU, 315 (PMN) functions,
Poly[d(G-m°C),], 1677 selection of, 437
pEMAGGFDEKAGGAQL- Poly(bD-Leu-.L-Ile-L-Ile-L-Lev), Polynucleotide, 1431
GVMQ-NH,, 1443 Solid state secondary Polynucleotides, 245
Peptide conformation, 201, structure of, 1477 Polyols, 491
621, 865 Polyelectrolyte systems, 953 Polypeptide continuity
Peptide conformation in Poly(L-Ala), 1843 constraint, 1271
solution, 769, 1237, 1443 Poly(L-Ala-L-Ile-L-Ile-L-Leu), Polypeptide segment, 1271
Peptide design, synthesis of, Solid state secondary Potential energy calculations,
conformationally structure of, 1477 of poly(L-Lys), 1553
restricted peptides, 209 Poly(L-arginine - HCl), 753 Preference functions,
Peptide stability, 1605 Poly(L-asparagine), 753 hydrophobicity, 255
Peptide structure, 1481 Poly(L-cysteine), 753 Preferential protein solvation,
Peptide structure and Poly(L-Glu), capillary gel equivalence of excluded
dynamics, 521 electrophoresis, 1299 volume treatment of, 1629
Peptide structures, 1003 Poly(L-Glu), circular dichroism Primary structure—
Peptides, 1481 study, 1299 conformation correlation,
Peptides, containing Poly(L-Glu), interaction with 873
dehydroaminoacidic spermine, 1299 Principal axis orientation of
residues, 1 Poly(L-glutamic acid), Raman scattering tensors,
Peptides, correlating containing spiropyran 1791
properties, 1405 units, 1505 Proanthocyanidin, 275
Peptidomimetics, 1073 Poly(L-glutamine), 753 Proline helix, 1195
Persistence analysis, 335 Poly(L-histidine), 753 Proline peptide bonds, 781
Persistence length, 1225 Poly(L-histidine - HCl), 753 Proline-rich polypeptides, 1019
Persistent volume proteins, in Poly(L-isoleucine), 753 Protein backbones, 1829
size exclusion Poly(L-leucine), 753 Protein, chemical
chromatography, 127 Poly(t-Leu-L-Ile-L-Ile-Gly), modifications of single side
pEYEAYDVKSGVAGG-NH,, Solid state secondary chains, 1659
1443 structure of, 1477 Protein conformational
Phase space, of molecular Poly(L-Leu-.L-Ile-L-Ile-L-Leu), changes, influence of
systems, 1307 Solid state secondary hydration on, 513, 1871
Photochromic polypeptides, structure of, 1477 Protein denaturant, dependent
1505 Poly(L-Leu-.-Ile-L-Leu), Solid baseline changes in size
Photochromism, of state secondary structure exclusion
spiropyran-containing of, 1477 chromatography, 127
polypeptides, 1505 Poly(L-Lys), substituted with Protein, docking, 219, 231
Photodimer conformation, amino acids, 873 Protein folding, 293, 1271, 1519
substituent effects, 713 Poly(L-Lys), substituted with Protein folding, a-helices, 163
Photodimer flexibility, X-pL-Ala,, side chains, 873 Protein folding, computer
substituent effects, 713 Poly(L-lysine - HBr), 753 simulation of, 329
Photomodulation, of Poly(L-methionine), 753 Protein folding, observed by
polypeptide conformation, Poly(L-phenylalanine), 753 size exclusion
1505 Poly(L-proline), 753 chromatography, 127
Photon correlation Poly(L-serine), 753 Protein, folding, Protein,
spectroscopy, particle size Poly(L-threonine), 753 activity, 1659
determination by, 453 Poly(L-tryptophane), 753 Protein hydration, solid state
Photoresponsive polymers, Poly(L-tyrosine), 753 13C NMR spectroscopic
light-induced Poly(sodium-L-aspartate), 753 studies of, 513, 1871
conformational changes Poly(sodium-L-glutamate), 753 Protein, molecular modeling,
in, 1505 Polymorphism of 219, 231
Poisson-Boltzmann equation, oligonucleotide crystals, Protein rotational diffusion,
1029 1715 determination by '°C off-
1918 SUBJECT INDEX
resonance rotating frame conformational difference Sequence dependence, 479
spin-lattice relaxation, of diastereomer and HPCL Shape analysis, 219, 231
1581 separation, 813 Shape space covering, 1389
Protein rotational diffusion, Repetitive domain, 1019 Shear flow, 1225
effect of internal motion, Reptation, biased, 1347, 1359 Sialic acid determination,
1581 Residues, 839 detection of polysialic acid
Protein rotational diffusion, of Resonances, 147 and its derivatives by, 453
globular proteins, 1581 Restrained energy Sickle hemoglobin
Protein, shape analysis, 219, minimization, 1083 polymerization, 735
231 Restrained molecular Side-chain rotamer restrictions
Protein solutions, description mechanics calculations, and helix formation, 163
of thermodynamic 1443 Silk fibroin, structure of by
nonideality in, 1629 Ribonuclease conformational solid state "N NMR, 847
Protein stabilization by inert transition, comparison of Simplified representation, 1519
solutes, preferential spectral and SEC analysis, Simulated annealing, 329
solvation and excluded 135
Simulation, of the SEC elution
volume concepts of, 1629 Ribonuclease conformational profiles for the
Protein stabilization by inert transition, observed by
ribonuclease
solutes, thermodynamic SEC, 135
conformational transition
analysis of, 1629 Rigid-rod molecules, 897 in guanidine
Protein—DNA interaction, rmsd, root mean square
hydrochloride, 135
energetics of, 1327 deviation, 1659
Single mutation, 1605
Proteins, 107, 1461 RNA secondary structure, 1389
Single-stranded nucleic acids,
Pseudopeptide analogues, 1135 ROESY, discrimination from
75
Pseudorotation, boat/twist- a-helix, 995
Singlet oxygen an agent able to
boat interconversion, 575 ROESY, observation of
photo-oxidize DNA, 239
Pseudorotation potential 3,o-helix, 995
Size exclusion
energy profile of Rotational correlation time,
chromatography, 903
deoxyribose in the B- and determination by ‘°C off-
Size exclusion
A-helicies, 37 resonance rotating frame
chromatography,
Pseudorotation, study of by spin-lattice relaxation,
conformational transition,
molecular dynamics, 575 1581
135
Pulsed field gel electrophoresis, Rotational correlation time, of
Size exclusion
dynamics of DNA during, globular proteins, 1581
chromatography, of
1347, 1359 Rouse-Zimm model, 409
persistent volume
Purine C8 proton exchange AT
proteins, 127
tracts, 943 16 S RNA, 1747
Size exclusion
16S RNA, urea-induced
Quantitative analysis, of a unfolding, 1747 chromatography, of
natural opioid peptide, Scaling, 329 protein folding, 127
1889 Scatchard analysis, 887 Size exclusion
Quinacrine, 1431 Screw senses, 1111 chromatography, protein
Secondary structure, 107, 245, denaturant dependent
Ramachandran’s plot, 1843 1461 baseline changes in, 127
Random RNA sequence, 1389 Secondary structure Size exclusion
Rayleigh scattering of fluctuations, 1519 chromatography,
Mossbauer radiation, 633 Secondary structure simulation and analysis of
RCT-COSY, relayed prediction, 255 the ribonuclease, 135
coherence-transfer COSY, Secondary structures, 1843 Size exclusion
1659 Self Consistent Reaction Field chromatography,
Reaction kinetics of drug/ (SCRF) calculations, 1851 simulation of elution
nucleotide binding, 1631 Separation of mixtures of profiles using empirical
Receptor selectivity, 1889 DNA, 1359 model, 127
Refolding loops in proteins, Sequence assignment, of Aib Small rings, dynamic light
1271 rich peptides, containing scattering of, 1757
Relation between aromatic residues, 995 Small rings, interference