B i o l o g y Concepts and Applications 8e Copyright 2011 Cengage Learning, Inc. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. 4466773355__0000__ffmm__pp0000ii--000011..iinndddd ii 44//2211//1100 88::1111 AAMM B i o l o g y Concepts and Applications 8e Cecie Starr Christine A. Evers Lisa Starr Australia • Brazil • Japan • Korea • Mexico • Singapore • Spain • United Kingdom • United States Copyright 2011 Cengage Learning, Inc. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. 4466773355__0000__ffmm__pp0000ii--000011..iinndddd iiiiii 44//2211//1100 88::1111 AAMM This is an electronic version of the print textbook. Due to electronic rights restrictions, some third party may be suppressed. Edition review has deemed that any suppressed content does not materially a ffect the over all learning experience. The publisher reserves the right to remove the contents from this title at any time if subsequent rights restrictions require it. For valuable information on pricing, previous editions, changes to current editions, and alternate format, please visit w ww.cengage.com/highered to search by ISBN#, author, title, or keyword for materials in your areas of interest. Copyright 2011 Cengage Learning, Inc. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. 5522660099__0000__ffmm__ppii--ppxxxxvvii..iinndddd iiii 22//11//1100 1111::3377::4433 PPMM Biology: Concepts and Applications, © 2011, 2008 Brooks/Cole, Cengage Learning Eighth Edition ALL RIGHTS RESERVED. No part of this work covered by the copyright herein Cecie Starr, Christine A. 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To learn more about Brooks/Cole, visit www.cengage.com/brookscole Purchase any of our products at your local college store or at our preferred online store www.cengagebrain.com Printed in the United States of America 1 2 3 4 5 6 7 14 13 12 11 10 Copyright 2011 Cengage Learning, Inc. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. 4466773355__0000__ffmm__pp0000ii--000011..iinndddd iivv 44//2211//1100 88::1111 AAMM CONTENTS IN BRIEF introduction unit v how plants work 1 Invitation to Biology 25 Plant Tissues 26 Plant Nutrition and Transport unit i principles of cellular life 27 Plant Reproduction and Development 2 Life’s Chemical Basis unit vi how animals work 3 Molecules of Life 4 Cell Structure 28 Animal Tissues and Organ Systems 5 Ground Rules of Metabolism 29 Neural Control 6 Where It Starts—Photosynthesis 30 Sensory Perception 7 How Cells Release Chemical Energy 31 Endocrine Control 32 Structural Support and Movement unit ii genetics 33 Circulation 8 DNA Structure and Function 34 Immunity 9 From DNA to Protein 35 Respiration 10 Controls Over Genes 36 Digestion and Human Nutrition 11 How Cells Reproduce 37 The Internal Environment 12 Meiosis and Sexual Reproduction 38 Reproduction and Development 13 Observing Patterns in Inherited Traits unit vii principles of ecology 14 Human Inheritance 15 Biotechnology 39 Animal Behavior 40 Population Ecology unit iii principles of evolution 41 Community Ecology 16 Evidence of Evolution 42 Ecosystems 17 Processes of Evolution 43 The Biosphere 18 Life’s Origin and Early Evolution 44 Human Effects on the Biosphere unit iv evolution and biodiversity 19 Viruses, Bacteria, and Archaeans 20 The Protists 21 Plant Evolution 22 Fungi 23 Animals I: Major Invertebrate Groups 24 Animals II: The Chordates Copyright 2011 Cengage Learning, Inc. 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May not be copied, scanned, or duplicated, in whole or in part. 4466773355__0000__ffmm__pp0000ii--000011..iinndddd vv 44//2211//1100 88::1111 AAMM DETAILED CONTENTS Swapping Electrons 27 INTRODUCTION Sharing Electrons 27 2.4 Why Atoms Interact 28 1 Invitation to Biology Ionic Bonds 28 Covalent Bonds 28 1.1 The Secret Life of Earth 3 Hydrogen Bonds 29 1.2 The Science of Nature 4 2.5 Water’s Life-Giving Properties 30 Life Is More Than the Sum of Its Parts 4 Each Water Molecule Is Polar 30 A Pattern in Life’s Organization 4 Water Is an Excellent Solvent 30 1.3 How Living Things Are Alike 6 Cohesion 31 Organisms Require Energy and Nutrients 6 Water Stabilizes Temperature 31 Organisms Sense and Respond to Change 7 2.6 Acids and Bases 32 Organisms Use DNA 7 Mercury Rising (revisited) 33 1.4 How Living Things Differ 8 1.5 Organizing Information About Species 10 3 Molecules of Life A Rose by Any Other Name . . . 10 1.6 The Nature of Science 12 3.1 Fear of Frying 37 Thinking About Thinking 12 3.2 The Molecules of Life—From Structure to Function 38 How Science Works 12 Functional Groups 38 1.7 Examples of Biology Experiments 14 What Cells Do to Organic Compounds 39 Potato Chips and Stomachaches 14 3.3 Carbohydrates 40 Butterflies and Birds 14 Simple Sugars 40 1.8 Asking Useful Questions 16 Short-Chain Carbohydrates 40 The Trouble With Trends 16 Complex Carbohydrates 40 Problems With Probability 16 3.4 Lipids 42 Bothering With Bias 17 Fats 42 1.9 Philosophy of Science 18 Phospholipids 43 About the Word “Theory” 18 Waxes 43 The Limits of Science 18 Steroids 43 The Secret Life of Earth (revisited) 19 3.5 Proteins—Diversity in Structure and Function 44 Amino Acids 44 Building Proteins 44 UNIT I PRINCIPLES OF CELLULAR LIFE Protein Structure 44 3.6 The Importance of Protein Structure 46 2 Life’s Chemical Basis 3.7 Nucleic Acids 47 Fear of Frying (revisited) 47 2.1 Mercury Rising 23 2.2 Start With Atoms 24 4 Cell Structure Isotopes and Radioisotopes 25 2.3 Why Electrons Matter 26 4.1 Food for Thought 51 Energy Levels 26 4.2 What, Exactly, Is a Cell? 52 Copyright 2011 Cengage Learning, Inc. 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May not be copied, scanned, or duplicated, in whole or in part. 4466773355__0000__ffmm__pp0000ii--000011..iinndddd vvii 44//2211//1100 88::1122 AAMM Traits Common to All Cells 52 Effects of Temperature, pH, and Salinity 81 Constraints on Cell Size 52 Help From Cofactors 81 Cell Theory 53 5.5 Metabolism: Organized, Enzyme-Mediated Reactions 82 4.3 Spying on Cells 54 Types of Metabolic Pathways 82 4.4 Membrane Structure and Function 56 Controls Over Metabolism 82 Membrane Proteins 56 Redox Reactions 83 Variations on the Model 57 5.6 Movement of Ions and Molecules 84 4.5 Introducing Bacteria and Archaeans 58 Diffusion Across Membranes 84 Biofilms 59 Turgor 85 4.6 Introducing Eukaryotic Cells 60 5.7 Membrane-Crossing Mechanisms 86 Passive Transport 86 4.7 The Nucleus 61 Active Transport 86 4.8 The Endomembrane System 62 5.8 Membrane Trafficking 88 Endoplasmic Reticulum 62 A Variety of Vesicles 62 A Toast to Alcohol Dehydrogenase (revisited) 89 Golgi Bodies 63 4.9 Mitochondria and Plastids 64 6 Where It Starts—Photosynthesis Mitochondria 64 6.1 Green Energy 93 Chloroplasts and Other Plastids 65 6.2 Sunlight as an Energy Source 94 4.10 The Dynamic Cytoskeleton 66 Properties of Light 94 4.11 Cell Surface Specializations 68 Pigments: The Rainbow Catchers 94 Matrixes Between and Around Cells 68 6.3 Exploring the Rainbow 96 Cell Junctions 69 6.4 Overview of Photosynthesis 97 4.12 A Visual Summary of Eukaryotic Cell Components 70 6.5 Light-Dependent Reactions 98 4.13 The Nature of Life 71 Capturing Light for Photosynthesis 98 Food for Thought (revisited) 71 The Noncyclic Pathway 98 Replacing Lost Electrons 98 5 Ground Rules of Metabolism Harvesting Electron Energy 98 The Cyclic Pathway 99 5.1 A Toast to Alcohol Dehydrogenase 75 6.6 Energy Flow in Photosynthesis 100 5.2 Energy and the World of Life 76 6.7 Light-Independent Reactions: The Sugar Factory 101 Energy Disperses 76 Energy’s One-Way Flow 76 6.8 Adaptations: Carbon-Fixing Pathways 102 5.3 Energy in the Molecules of Life 78 Green Energy (revisited) 103 Energy In, Energy Out 78 Why Earth Does Not Go Up in Flames 78 7 How Cells Release Chemical Energy ATP—The Cell’s Energy Currency 79 7.1 When Mitochondria Spin Their Wheels 107 5.4 How Enzymes Work 80 Helping Substrates Get Together 80 7.2 Extracting Energy From Carbohydrates 108 Orienting Substrates in Positions That Favor Reaction 80 Evolution of Earth’s Atmosphere 108 Inducing a Fit Between Enzyme and Substrate 80 Carbohydrate Breakdown Pathways 108 Shutting Out Water Molecules 81 7.3 Glycolysis—Glucose Breakdown Starts 110 Copyright 2011 Cengage Learning, Inc. 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May not be copied, scanned, or duplicated, in whole or in part. 4466773355__0000__ffmm__pp0000ii--000011..iinndddd vviiii 44//2211//1100 88::1122 AAMM 7.4 Second Stage of Aerobic Respiration 112 9.6 Mutated Genes and Their Protein Products 146 The Krebs Cycle 112 What Causes Mutations? 147 7.5 Aerobic Respiration’s Big Energy Payoff 114 Ricin and Your Ribosomes (revisited) 148 Electron Transfer Phosphorylation 114 Summing Up: The Energy Harvest 115 10 Controls Over Genes 7.6 Fermentation Pathways 116 10.1 Between You and Eternity 151 Alcoholic Fermentation 116 10.2 Gene Expression in Eukaryotic Cells 152 Lactate Fermentation 116 Control of Transcription 152 7.7 Alternative Energy Sources in the Body 118 mRNA Processing 153 Energy From Fats 119 mRNA Transport 153 Energy From Proteins 119 Translational Control 153 When Mitochondria Spin Their Wheels (revisited) 119 Post- Translational Modification 153 10.3 There’s a Fly in My Research 154 Homeotic Genes 154 UNIT II GENETICS Filling in Details of Body Plans 155 10.4 A Few Outcomes of Gene Controls 156 X Chromosome Inactivation 156 8 DNA Structure and Function Male Sex Determination in Humans 156 8.1 A Hero Dog’s Golden Clones 123 Flower Formation 157 8.2 Eukaryotic Chromosomes 124 10.5 Gene Control in Bacteria 158 The Lactose Operon 158 Chromosome Number 124 Lactose Intolerance 159 Types of Chromosomes 125 Between You and Eternity (revisited) 159 8.3 The Discovery of DNA’s Function 126 Early and Puzzling Clues 126 Confirmation of DNA’s Function 127 11 How Cells Reproduce 8.4 The Discovery of DNA’s Structure 128 11.1 Henrietta’s Immortal Cells 163 DNA’s Building Blocks 128 11.2 Multiplication by Division 164 DNA’s Base Pair Sequence 129 The Life of a Cell 164 8.5 Fame and Glory 130 A Bigger Picture of Cell Division 165 8.6 DNA Replication and Repair 130 11.3 Mitosis 166 Proofreading 131 11.4 Cytokinesis: Division of Cytoplasm 168 8.7 Using DNA To Duplicate Existing Mammals 132 11.5 Controls Over Cell Division 169 A Hero Dog’s Golden Clones (revisited) 133 11.6 Cancer: When Control Is Lost 170 Henrietta’s Immortal Cells (revisited) 171 9 From DNA to Protein 9.1 Ricin and Your Ribosomes 137 12 Meiosis and Sexual Reproduction 9.2 The Nature of Genetic Information 138 12.1 Why Sex? 175 Converting a Gene to an RNA 138 12.2 Meiosis Halves the Chromosome Number 176 Converting mRNA to Protein 138 Introducing Alleles 176 9.3 Transcription 140 What Meiosis Does 176 Post-Transcriptional Modifications 141 12.3 The Process of Meiosis 178 9.4 RNA and the Genetic Code 142 Meiosis I 178 rRNA and tRNA —The Translators 143 Meiosis II 179 9.5 Translating the Code: RNA to Protein 144 12.4 How Meiosis Introduces Variations in Traits 180 Copyright 2011 Cengage Learning, Inc. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. 4466773355__0000__ffmm__pp0000ii--000011..iinndddd vviiiiii 44//2211//1100 88::1122 AAMM Crossing Over in Prophase I 180 Duplication 210 Segregation of Chromosomes Into Gametes 180 Deletion 210 12.5 From Gametes to Offspring 182 Inversion 210 Gamete Formation in Plants 182 Translocation 210 Gamete Formation in Animals 182 Chromosome Changes in Evolution 210 Fertilization 182 14.6 Heritable Changes in the Chromosome Number 212 12.6 Mitosis and Meiosis—An Ancestral Connection? 184 Autosomal Change and Down Syndrome 212 Why Sex? (revisited) 185 Change in the Sex Chromosome Number 212 Female Sex Chromosome Abnormalities 212 13 Observing Patterns in Inherited Traits Male Sex Chromosome Abnormalities 213 13.1 Menacing Mucus 189 14.7 Genetic Screening 214 Prenatal Diagnosis 214 13.2 Mendel, Pea Plants, and Inheritance Patterns 190 Preimplantation Diagnosis 215 Mendel’s Experimental Approach 190 Inheritance in Modern Terms 191 Shades of Skin (revisited) 215 13.3 Mendel’s Law of Segregation 192 13.4 Mendel’s Law of Independent Assortment 194 15 Biotechnology The Contribution of Crossovers 195 15.1 Personal DNA Testing 219 13.5 Beyond Simple Dominance 196 15.2 Cloning DNA 220 Codominance 196 Incomplete Dominance 196 cDNA Cloning 221 Epistasis 197 15.3 From Haystacks to Needles 222 Pleiotropy 197 Isolating Genes 222 13.6 Complex Variation in Traits 198 PCR 222 Continuous Variation 198 15.4 DNA Sequencing 224 Environmental Effects on Phenotype 198 The Human Genome Project 225 Menacing Mucus (revisited) 199 15.5 Genomics 226 DNA Profiling 226 14 Human Inheritance 15.6 Genetic Engineering 228 14.1 Shades of Skin 203 15.7 Designer Plants 228 14.2 Human Genetic Analysis 204 15.8 Biotech Barnyards 230 Types of Genetic Variation 204 Knockouts and Organ Factories 230 14.3 Autosomal Inheritance Patterns 206 15.9 Safety Issues 231 The Autosomal Dominant Pattern 206 The Autosomal Recessive Pattern 207 15.10 Genetically Modified Humans 232 Getting Better 232 14.4 X-Linked Inheritance Patterns 208 Red–Green Color Blindness 208 Getting Worse 232 Hemophilia A 209 Getting Perfect 232 Duchenne Muscular Dystrophy 209 Getting There 233 14.5 Heritable Changes in Chromosome Structure 210 Personal DNA Testing (revisited) 233 Copyright 2011 Cengage Learning, Inc. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. 4466773355__0000__ffmm__pp0000ii--000011..iinndddd iixx 44//2211//1100 88::1122 AAMM