Table Of Content

Biological Psychiatry A Journal of Psychiatric Research Contents Volume 38, Number 1, July 1, 1995 EDITORIAL Early Intervention for Schizophrenia: Can the Course of the Illness Be Altered? Richard Jed Wyatt ORIGINAL ARTICLES Decreased DOPAC in the Anterior Cingulate Cortex of Individuals with Schizophrenia Richard Jed Wyatt, Farouk Karoum, and Manuel F. Casanova Inversion of the Hemispheric Laterality of the Anterior Cingulate Gyrus in Schizophrenics Alfonso M. Albanese, Alicia B. Merlo, Tomas A. Mascitti, Elba B. Tornese, Elena E. Gomez, Victor Konopka, and Eduardo F. Albanese Evidence in Postmortem Brain Tissue for Decreased Numbers of Hippocampal Nicotinic Receptors in Schizophrenia Robert Freedman, Michael Hall, Lawrence E. Adler, and Sherry Leonard Selected Quantitative EEG (QEEG) and Event-Related Potential (ERP) Variables as Discriminators for Positive and Negative Schizophrenia Montserrat Gerez and Armando Tello Schizophrenic Patients with Deficit Syndrome Have Higher Plasma Homovanillic Acid Concentrations and Ventricular Enlargement Masashi Nibuya, Shigenobu Kanba, Utako Sekiya, Eiji Suzuki, Yoko Matsuo, Norihisa Konoshita, Futoshi Shintani, Gohei Yagi, and Masahiro Asai Olfactory Indentification Ability in Pre- and Postmenopausal Women with Schizophrenia Lili C. Kopala, Kim Good, and William G. Honer BRIEF REPORTS Neuroleptic Treatment and Negative Symptoms in Deficit and Nondeficit Schizophrenia Juan R. Bustillo, Brian Kirkpatrick, and Robert W. Buchanan Affective Reactivity of Language and the Startle Response in Schizophrenia Nancy M. Docherty and Christian Grillon Volume 38, Number 2, July 15, 1995 EDITORIAL Elmer Ernest Southard (1876-1920) Manuel F. Casanova ORIGINAL ARTICLES Effects of Tryptophan Depletion on Responses to Yohimbine in Healthy Human Subjects Andrew W. Goddard, Dennis S. Charney, Mark Germine, Scott W. Woods, George R. Heninger, John H. Krystal, Wayne K. Goodman, and Lawrence H. Price White Matter Signal Hyperintensities in the Brains of Patients with Late Paraphrenia and the Normal, Community-Living Elderly Robert Howard, Timothy Cox, Osvaldo Almeida, Richard Mullen, Phillipa Graves, Adrienne Reveley, and Raymond Levy 92 Human Oculomotor Function: Reliability and Diurnal Variation Peter Roy-Byrne, Allen Radant, Dane Wingerson, and Deborah S. Cowley 98 All-Night EEG Spectral Analysis as a Tool for the Prediction of Clinical Response to Antidepressant Treatment Rémy Luthringer, Richard Minot, Michel Toussaint, Francoise Calvi-Gries, Nicolas Schaltenbrand, and Jean-Paul Macher Modifiability of Neuropsychological Dysfunction in Schizophrenia Lauren M. Tompkins, Robert S. Goldman, and Bradley N. Axelrod 112 Decreased Dopamine Uptake into Platelet Storage Granules in Gilles de La Tourette Disease Jose Martin Rabey, Ziona Oberman, Eran Graff, and Amos D. Korczyn CASE REPORTS 116 A Case of Bipolar Disorder with Balanced Chromosomal Translocation Hiroshi Kunugi, Shinichiro Nanko, and Hajime Kazamatsuri 119 Melatonin Treatment of a Non-24-Hour Sleep—Wake Cycle in a Blind Retarded Child Odile Lapierre and Marie Dumont BRIEF REPORTS 123. Drug Screening in “Normal” Controls Neal R. Swerdlow, Mark A. Geyer, William Perry, Kristin Cadenhead, and David L. Braff 125 Acute Effect of Exercise on Human Blood Platelet Serotonin Uptake and Monoamine Oxidase Activity Peer N. Jensen, Holger J. Moller, Donald F. Smith, and Raben Rosenberg 128 Serial Dexamethasone Suppression Tests by Measuring Urinary Cortisol among Rapidly Cycling Patients Shin-ichiro Tomitaka, Kaoru Sakamoto, Itaru Kojima, and Hiroko Fujita CORRESPONDENCE 131 Osteoporosis and Schizophrenia: Can We Limit Known Risk Factors?; Phasic Asymmetries in Phasic Affective Disorders; Magnetic Resonance Imaging Evaluation of Brain Iron Levels; Response; Buprenorphine for Human Immunovirus-Positive Opiate-Dependent Patients Volume 38, Number 3, August 1, 1995 EDITORIAL 137 Undivided Publication of Research Findings: A Uniform Editorial Policy of the Consortium of Editors of Journals Relating to Human Development and Psychopathology Wagner H. Bridger ORIGINAL ARTICLES 138 m-Chlorophenylpiperazine in Patients with Obsessive Compulsive Disorder: Absence of Symptom Exacerbation Wayne K. Goodman, Christopher J. McDougle, Lawrence H. Price, Linda C. Barr, Oscar F. Hills, James F. Caplik, Dennis S. Charney, and George R. Heninger Auditory Event-Related Brain Potentials in Autistic Children and Three Different Control Groups Chantal Kemner, Marinus N. Verbaten, Juliane M. Cuperus, Gert Camfferman, and Herman van Engeland Plasma Neurotransmitters, Blood Pressure, and Heart Rate During Supine-Resting, Orthostasis, and Moderate Exercise Conditions in Major Depressed Patients Fuad Lechin, Bertha van der Dijs, Beatriz Orozco, Marcel E. Lechin, Scarlet Bdez, Alex E. Lechin, Isais Rada, Emilio Acosta, Luis Arocha, Vladimir Jimenéz, Gladys Leén, and Zulay Garcia Nocturnal/Daytime Urine Noradrenergic Measures and Sleep in Combat-Related PTSD Thomas A. Mellman, Adarsh Kumar, Renee Kulick-Bell, Mahendra Kumar, and Bruce Nolan Reduced Echogenicity of Brainstem Raphe Specific to Unipolar Depression: A Transcranial Color-Coded Real-Time Sonography Study Georg Becker, Thomas Becker, Michael Struck, Alfred Lindner, Klaus Burzer, Wolfgang Retz, Ulrich Bogdahn, and Helmut Beckmann Plasma 3-Methoxy-4-Hydroxyphenylglycol (MHPG) and Clinical Symptoms in Alzheimer’s Disease Brian A. Lawlor, Linda M. Bierer, Theresa M. Ryan, James Schmeidler, Peter J. Knott, Lizette L. Williams, Richard C. Mohs, and Kenneth L. Davis CASE REPORTS Recurrent Absence Status Epilepticus and Hyponatremia in a Patient with Polydipsia Alberto Primavera, Alessandra Fonti, Laura Giberti, and Leonardo Cocito Tricyclic-Induced Musical Hallucinations and States of Relative Sensory Deprivation Takeshi Terao Neuroleptic-Induced Emesis: A New Indication for Clozapine? Juan R. Bustillo and Robert W. Buchanan Clozapine in Tardive Tourette Syndrome Emily Jaffe, Fabien Tremeau, Zafar Sharif, and Ronald Reider BRIEF REPORTS Negative Correlations between Alpha-1-Acid-Glycoprotein Plasma Level and Response to Haloperidol in the Acute Treatment of Schizophrenia Ilan Levinson and Stewart Levine Growth Hormone Response to Clonidine in Nondepressed Patients with a History of Suicide Attempts William Pitchot, Michel Hansenne, Antonio Gonzalez Moreno, and Marc Ansseau NEWS AND NOTES Volume 38, Number 4, August 15, 1995 EDITORIAL Nonspecific Abnormalities in Psychiatry: Do They Reflect an Ordered Pathway of Brain Dysfunction? Joseph I. Tracy White Matter Signal Hyperintensities in the Brains of Patients with Late Paraphrenia and the Normal, Community-Living Elderly Robert Howard, Timothy Cox, Osvaldo Almeida, Richard Mullen, Phillipa Graves, Adrienne Reveley, and Raymond Levy 92 Human Oculomotor Function: Reliability and Diurnal Variation Peter Roy-Byrne, Allen Radant, Dane Wingerson, and Deborah S. Cowley 98 All-Night EEG Spectral Analysis as a Tool for the Prediction of Clinical Response to Antidepressant Treatment Rémy Luthringer, Richard Minot, Michel Toussaint, Frangoise Calvi-Gries, Nicolas Schaltenbrand, and Jean-Paul Macher Modifiability of Neuropsychological Dysfunction in Schizophrenia Lauren M. Tompkins, Robert S. Goldman, and Bradley N. Axelrod 112 Decreased Dopamine Uptake into Platelet Storage Granules in Gilles de La Tourette Disease Jose Martin Rabey, Ziona Oberman, Eran Graff, and Amos D. Korczyn CASE REPORTS 116 A Case of Bipolar Disorder with Balanced Chromosomal Translocation Hiroshi Kunugi, Shinichiro Nanko, and Hajime Kazamatsuri 119 Melatonin Treatment of a Non-24-Hour Sleep—Wake Cycle in a Blind Retarded Child Odile Lapierre and Marie Dumont BRIEF REPORTS 123 Drug Screening in “Normal” Controls Neal R. Swerdlow, Mark A. Geyer, William Perry, Kristin Cadenhead, and David L. Braff 125 Acute Effect of Exercise on Human Blood Platelet Serotonin Uptake and Monoamine Oxidase Activity Peer N. Jensen, Holger J. Moller, Donald F. Smith, and Raben Rosenberg 128 Serial Dexamethasone Suppression Tests by Measuring Urinary Cortisol among Rapidly Cycling Patients Shin-ichiro Tomitaka, Kaoru Sakamoto, Itaru Kojima, and Hiroko Fujita CORRESPONDENCE 131 Osteoporosis and Schizophrenia: Can We Limit Known Risk Factors?; Phasic Asymmetries in Phasic Affective Disorders; Magnetic Resonance Imaging Evaluation of Brain Iron Levels; Response; Buprenorphine for Human Immunovirus-Positive Opiate-Dependent Patients Volume 38, Number 3, August 1, 1995 EDITORIAL 137 Undivided Publication of Research Findings: A Uniform Editorial Policy of the Consortium of Editors of Journals Relating to Human Development and Psychopathology Wagner H. Bridger ORIGINAL ARTICLES 138 m-Chlorophenylpiperazine in Patients with Obsessive Compulsive Disorder: Absence of Symptom Exacerbation Wayne K. Goodman, Christopher J. McDougle, Lawrence H. Price, Linda C. Barr, Oscar F. Hills, James F. Caplik, Dennis S. Charney, and George R. Heninger Auditory Event-Related Brain Potentials in Autistic Children and Three Different Control Groups Chantal Kemner, Marinus N. Verbaten, Juliane M. Cuperus, Gert Camfferman, and Herman van Engeland Plasma Neurotransmitters, Blood Pressure, and Heart Rate During Supine-Resting, Orthostasis, and Moderate Exercise Conditions in Major Depressed Patients Fuad Lechin, Bertha van der Dijs, Beatriz Orozco, Marcel E. Lechin, Scarlet Baez, Alex E. Lechin, Isais Rada, Emilio Acosta, Luis Arocha, Vladimir Jimenéz, Gladys Leon, and Zulay Garcia Nocturnal/Daytime Urine Noradrenergic Measures and Sleep in Combat-Related PTSD Thomas A. Mellman, Adarsh Kumar, Renee Kulick-Bell, Mahendra Kumar, and Bruce Nolan Reduced Echogenicity of Brainstem Raphe Specific to Unipolar Depression: A Transcranial Color-Coded Real-Time Sonography Study Georg Becker, Thomas Becker, Michael Struck, Alfred Lindner, Klaus Burzer, Wolfgang Retz, Ulrich Bogdahn, and Helmut Beckmann Plasma 3-Methoxy-4-Hydroxyphenylglycol (MHPG) and Clinical Symptoms in Alzheimer’s Disease Brian A. Lawlor, Linda M. Bierer, Theresa M. Ryan, James Schmeidler, Peter J. Knott, Lizette L. Williams, Richard C. Mohs, and Kenneth L. Davis CASE REPORTS Recurrent Absence Status Epilepticus and Hyponatremia in a Patient with Polydipsia Alberto Primavera, Alessandra Fonti, Laura Giberti, and Leonardo Cocito Tricyclic-Induced Musical Hallucinations and States of Relative Sensory Deprivation Takeshi Terao Neuroleptic-Induced Emesis: A New Indication for Clozapine? Juan R. Bustillo and Robert W. Buchanan Clozapine in Tardive Tourette Syndrome Emily Jaffe, Fabien Tremeau, Zafar Sharif, and Ronald Reider BRIEF REPORTS Negative Correlations between Alpha-1-Acid-Glycoprotein Plasma Level and Response to Haloperidol in the Acute Treatment of Schizophrenia Ilan Levinson and Stewart Levine Growth Hormone Response to Clonidine in Nondepressed Patients with a History of Suicide Attempts William Pitchot, Michel Hansenne, Antonio Gonzalez Moreno, and Marc Ansseau NEWS AND NOTES Volume 38, Number 4, August 15, 1995 EDITORIAL Nonspecific Abnormalities in Psychiatry: Do They Reflect an Ordered Pathway of Brain Dysfunction? Joseph I. Tracy ORIGINAL ARTICLES Cerebrospinal Fluid Neuropeptides in Alzheimer’s Disease and Vascular Dementia Markus Heilig, Magnus Sjégren, Kaj Blennow, Rolf Ekman, and Anders Wallin Immunoglobulin Production in Vitro in Major Depression: A Pilot Study on the Modulating Action of Endogenous Cortisol Frans W. Kok, Cobi J. Heijnen, Jan A. Bruijn, Herman G.M. Westenberg, and Jan M. van Ree Polyamines and Their Metabolizing Enzymes in Human Frontal Cortex and Hippocampus: Preliminary Measurements in Affective Disorders Gad M. Gilad, Varda H. Gilad, Manuel F. Casanova, and Robert A. Casero, Jr. Prolactin Response to Buspirone Challenge in the Presence of Dopaminergic Blockade Douglas D. Maskall, Athanasios P. Zis, Raymond W. Lam, Campbell M. Clark, and Annie J. Kuan Rebreathing Tests in Panic Disorder Laszlo A. Papp, Jose M. Martinez, Donald F. Klein, Jeremy D. Coplan, and Jack M. Gorman Monosialoganglioside Cotreatment Prevents Haloperidol Treatment-Associated Loss of Cholinergic Enzymes in Rat Brain Sahebarao P. Mahadik and Sukdeb Mukherjee Prefrontal Cortical and Hippocampal Modulation of Haloperidol-Induced Catalepsy and Apomorphine-Induced Stereotypic Behaviors in the Rat Barbara K. Lipska, George E. Jaskiw, Allen R. Braun, and Daniel R. Weinberger BRIEF REPORTS Effects of Cocaine on D; and D, Receptor Expression in the Human Striatum James H. Meador-Woodruff, Karley Y. Little, Scott P. Damask, and Stanley J. Watson Plasma Prolactin and Plasma Homovanillic Acid: Predictors of Clinical Response in Schizophrenia Ricardo Davila, Miguel A. Gonzalez, Mercedes Zumarraga, Isabel Andia, Jose Guimon, Raul R. Silva, and Arnold J. Friedhoff Affective Disorders in Holland after Prenatal Exposure to the 1957 A2 Influenza Epidemic Alan S. Brown, Ezra S. Susser, Shang P. Lin, and Jack M. Gorman Serotonin—Induced Platelet Calcium Mobilization Is Enhanced in Bulimia Nervosa but Not in Anorexia Nervosa Yasumasa Okamoto, Yuri Okamoto, Ariyuki Kagaya, Satoshi Tamiya, Yasunobu Fujita, Yoshikuni Tohoda, Nobutaka Motohashi, and Shigeto Yamawaki Volume 38, Number 5, September 1, 1995 EDITORIAL Drug Development and the Deficit Syndrome Schizophrenia Brian Kirkpatrick and William T. Carpenter ORIGINAL ARTICLES Asymmetry of Temporal Lobe Phosphorous Metabolism in Schizophrenia: A *'Phosphorous Magnetic Resonance Spectroscopic Imaging Study Raymond F. Deicken, Giovanna Calabrese, Edward L. Merrin, Sophia Vinogradov, George Fein, and Michael W. Weiner Language Comprehension in Schizophrenia: Trait or State Indicator? Ruth Condray, Daniel P. van Kammen, Stuart R. Steinhauer, Annette Kasparek, and Jeffrey K. Yao Cytokine Production in Drug-Free and Neuroleptic-Treated Schizophrenic Patients Hanna Bessler, Zvi Levental, Leon Karp, Ilan Modai, Meir Djaldetti, and Abraham Weizman Quantitative EEG in Never-Treated Schizophrenic Patients Masao Omori, Yoshifumi Koshino, Tetsuhito Murata, Ichiro Murata, Masashi Nishio, Kazumasa Sakamoto, Tan Horie, and Kiminori Isaki Effect of Pindolol Pretreatment on MK-212-Induced Plasma Cortisol and Prolactin Responses in Normal Men Herbert Y. Meltzer and Michael Maes Effects of the Benzodiazepine Antagonist Flumazenil in PTSD Penny K. Randall, J. Douglas Bremner, John H. Krystal, Linda M. Nagy, George R. Heninger, Andreas L. Nicolaou, and Dennis S. Charney Growth Hormone Response to Growth Hormone-Releasing Hormone and Clonidine in Depression Horst Gann, Dieter Riemann, Siegfried Stoll, Mathias Berger, and Walter E. Miiller BRIEF REPORTS Cerebrospinal Fluid Corticotropin-Releasing Hormone, Vasopressin, and Oxytocin Concentrations in Treated Patients with Major Depression and Controls Andrew F. Pitts, Stephen D. Samuelson, William H. Meller, Garth Bissette, Charles B. Nemeroff, and Roger G. Kathol Fluctuation of Tardive Dyskinesia Michael P. Caligiuri, James B. Lohr, Rebecca M. Vaughan, and LouAnn McAdams Effects of Sleep Deprivation on Spontaneous Eye Blink Rate and Alpha EEG Power Giuseppe Barbato, Gianluca Ficca, Michele Beatrice, Margherita Casiello, Giovanni Muscettola, and Franco Rinaldi CORRESPONDENCE Glucose Metabolism in Murderers; Response; Alcohol Abuse and HIV; Response NEWS AND NOTES Volume 38, Number 6, September 15, 1995 EDITORIAL Sexual Dimorphism in the Brain: It’s Worse Than You Thought Brian Kirkpatrick and Nancy L. Bryant ORIGINAL ARTICLES A Prospective Follow-up Study of Brain Morphology and Cognition in First-Episode Schizophrenic Patients: Preliminary Findings Lynn E. DeLisi, William Tew, Shu-hong Xie, Anne L. Hoff; Michael Sakuma, Maureen Kushner, Gregory Lee, Karen Shedlack, Angela M. Smith, and Roger Grimson Platelet Monamine Oxidase Activity Levels in Subgroups of Alcoholics: Diagnostic, Temporal, and Clinical Correlates Robert M. Anthenelli, Tom L. Smith, Claire E. Craig, Boris Tabakoff, and Marc A. Schuckit Menstrual Phase-Independent Retrieval Deficit in Women with PMS Pamela A. Keenan, Laurie A. Lindamer, and Soo K. Jong 378 Fear-Potentiated Startle in Posttraumatic Stress Disorder C. A. Morgan III, Christian Grillon, Steven M. Southwick, Michael Davis, and Dennis S. Charney 386 Behavioral Laterality in Individuals with Gilles de la Tourette’s Syndrome and Basal Ganglia Alterations: A Preliminary Report M. Yank: Yazgan, Bradley Peterson, Bruce E. Wexler, and James F. Leckman REVIEW ARTICLE 391 Sleep Research in Depressive Illness: Clinical Implications—A Tasting Menu David J. Kupfer CASE REPORTS 404 Vulnerability to Fluoxetine-Induced Indifference Syndrome among Opiate Addicts: A Case Report Gilles Bertschy and Pierre Baumann 407 Clomipramine Efficacy for Tourette Syndrome and Major Depression: A Case Study lulian Iancu, Moshe Kotler, Avraham Bleich, and Elie Lepkifker BRIEF REPORTS 410 Prior Antidepressant Treatment Does Not Have an Impact on Response to Desipramine Treatment in Major Depression L. Trevor Young, Robert G. Cooke, Anthony J. Levitt, and Russell T. Joffe 413 No Difference in the Effect of Biperiden and Amantadine on Negative Symptoms in Medicated Chronic Schizophrenic Patients Henry Silver and Nabil Geraisy CORRESPONDENCE 416 Dopamine Uptake in Platelets; Response; Prolactin Is Synthesized and Secreted by the Endometrium 418 CALL FOR PAPERS Volume 38, Number 7, October 1, 1995 EDITORIAL 419 Transcranial Magnetic Stimulation: A Potential New Frontier in Psychiatry Robert H. Belmaker and Amos Fleischmann ORIGINAL ARTICLES 422 Variability of Brain Lithium Levels during Maintenance Treatment: A Magnetic Resonance Spectroscopy Study Gary S. Sachs, Perry F. Renshaw, Beny Lafer, Andrew L. Stoll, Alexander R. Guimaraes, Jerrold F. Rosenbaum, and R. Gilberto Gonzalez 429 Regional '**Xenon Cerebral Blood Flow and Cerebral ?°"Tc-HMPAO Uptake in Patients with Obsessive-Compulsive Disorder Before and During Treatment Robert T. Rubin, Jambur Ananth, Javier Villanueva-Meyer, Peter G. Trajmar, and Ismael Mena Abnormal Brain Glucose Metabolism in the Delusional Misidentification Syndromes: A Positron Emission Tomography Study in Alzheimer Disease Marc J. Mentis, Edward A. Weinstein, Barry Horwitz, Andrew R. McIntosh, Pietro Pietrini, Gene E. Alexander, Maura Furey, and Declan G.M. Murphy Effects of Ipsapirone on Plasma Cortisol and Body Temperature in Major Depression Herbert Y. Meltzer and Michael Maes The Role of Pterins in Depression and the Effects of Antidepressive Therapy M.T. Abou-Saleh, David N. Anderson, James Collins, Kevin Hughes, Richard J. Cattell, Christopher G.B. Hamon, and John A. Blair Changes in Platelet 3-H-Imipramine Binding: Influences of Protein Concentration of Varying Proportions of Cytosol or Intact Platelets and Displacing Agents Used P. Rosel-Soria, J. Vallejo, M. Oros, J. Serrallonga, J.M. Menchon, and M.A. Navarro Long-Term Decrease in the Hippocampal [*H] Inositoltriphosphate Binding Following Repeated Electroshock in the Rat Jorn Kragh, Ma:tin B. Jorgensen, Nils H. Diemer, and Tom G. Bolwig Attributes of Heavy vs. Occasional Marijuana Smokers in a College Population Elena Kouri, Harrison G. Pope, Jr., Deborah A. Yurgelun-Todd, and Staci Gruber CASE REPORT Diagnostic Specificity of Focal White Matter Abnormalities in Bipolar and Unipolar Mood Disorder Renee Dupont, Nelson Butters, Kimberly Schafer, Thomine Wilson, John Hesselink, and J. Christian Gillin BRIEF REPORT Abnormal Saccadic Eye Movements Associated with Positive Family History Schizophrenics Barry D. Schwartz, Beth A. O’Brien, William J. Evans, Barbara E. McDermott, Frederick J. Sautter Jr., and Daniel K. Winstead NEWS AND NOTES Volume 38, Number 8, October 15, 1995 IN MEMORIAM Eli Robins, M.D., 1921-1994 George E. Murphy EDITORIAL The Study of Paranoia and Suspiciousness Brian Kirkpatrick and Xavier F. Amador ORIGINAL ARTICLES Psychiatric Status After Human Fetal Mesencephalic Tissue Transplantation in Parkinson’s Disease Lawrence H. Price, Dennis D. Spencer, Kenneth L. Marek, Richard J. Robbins, Csaba Leranth, Anita Farhi, Frederick Naftolin, Robert H. Roth, Benjamin S. Bunney, Paul B. Hoffer, Robert Makuch, and D. Eugene Redmond, Jr. Electroencephalographic Sleep Profiles in Single-Episode and Recurrent Unipolar Forms of Major Depression: I. Comparison During Acute Depressive States Michael E. Thase, David J. Kupfer, Daniel J. Buysse, Ellen Frank, Anne D. Simons, Ann B. McEachran, Katherine F. Rashid, and Victoria J. Grochocinski 516 The Relationship of Minor Physical Anomalies and Other Putative Indices of Developmental Disturbance in Schizophrenia to Abnormalities of Cerebral Structure on Magnetic Resonance Imaging Eadbhard O’Callaghan, Peter Buckley, Cathy Madigan, Oonagh Redmond, John P. Stack, Anthony Kinsella, Conall Larkin, Joseph T. Ennis, and John L. Waddington 525 Effects of Acute Intravenous Clomipramine on Obsessive-Compulsive Symptoms and Response to Chronic Treatment Emanuela Mundo, Laura Bellodi, and Enrico Smeraldi 532 Oral Physostigmine in Alzheimer’s Disease: Effects on Norepinephrine and Vasopressin in Cerebrospinal Fluid and Plasma Elaine R. Peskind, Dane Wingerson, Marcella Pascualy, Leon Thal, Richard C. Veith, Daniel M. Dorsa, Sol Bodenheimer, and Murray A. Raskind 539 Delayed Startle Sensitization Distinguishes Rats Exposed to One or Three Stress Sessions: Further Evidence Toward an Animal Model of PTSD Richard J. Servatius, John E. Ottenweller, and Benjamin H. Natelson 547 Salivary Cortisol Responses and the Risk for Substance Abuse in Prepubertal Boys Howard B. Moss, Michael M. Vanyukov, and Christopher S. Martin CASE REPORT 556 Fluoxetine and Visual Hallucinations in Dementia Sabiha J. Omar, David Robinson, Helen D. Davies, Terry P. Miller, and Jared R. Tinklenberg BRIEF REPORT 559 Sodium Lactate Infusion in Fibromyalgia Patients Lars Tanum and Ulrik Fr. Malt NEWS AND NOTES 562 Ethics for the Society of Biological Psychiatry 566 CALL FOR PAPERS 567 ERRATUM Volume 38, Number 9, November 1, 1995 EDITORIAL 569 Lateralization in the Frontal Lobes: Searching the Right (and Left) Way Elkhonon Goldberg and Kenneth Podell ORIGINAL ARTICLES 572 Evidence for Heritability of Biogenic Amine Levels in the Cerebrospinal Fluid of Rhesus Monkeys A. Susan Clarke, Candace M. Kammerer, Karen P. George, David J. Kupfer, William T. McKinney, M. Anne Spence, and Gary W. Kraemer 578 Benzodiazepines as Antidepressants: Does GABA Play a Role in Depression? Frederick Petty, Madhukar H. Trivedi, Mark Fulton, and A. John Rush