Table Of Content

Biol. Chem., Vol. 378, pp. 1541 - 1549, December 1997 - Copyright © by Walter de Gruyter & Co - Berlin - New York Contents Biological Chemistry, Volume 378, 1997 Editorials Fritz, H. and W. Bode Auerbach, G. and H. Nar Robert Huber — A Life Devoted to Protein Structures The Pathway from GTP to Tetrahydrobiopterin: Three-Dimensional Structures of GTP and Functions Cyclohydrolase | and 6-Pyruvoy! Tetrahydropterin Hagmann, M. and W. Schaffner Synthase Rolf M. Zinkernagel — Felix Hoppe-Seyler Lecturer 1997 Baumeister, W., Z. Cejka, M. Kania and E. Seemiiller The Proteasome: A Macromolecular Assembly Schaffner, W Designed to Confine Proteolysis to a Nanocompartment Schaffner, W. Granny’s Remedy Explained at the Molecular Level: Bentley, N. J. and A. M. Carr Helenalin Inhibits NF-«B DNA Structure-Dependent Checkpoints in Model Systems Schaffner, W. Hershey Heaven Revisited Benz, J. and A. Hofmann Annexins: From Structure to Function Sies, H. and J. Krutmann Highlight: Molecular and Cellular Responses to Berg, A. and A. De Kok 2-Oxo Acid Dehydrogenase Multienzyme Ultraviolet Radiation Complexes. The Central Role of the Lipoy! Guest Editorials Besse, D., N. Budisa, W. Karnbrock, C. Minks, Aguzzi, A. H.-J. Musiol, S. Pegoraro, F. Siedler, E. Weyher and Prions and Antiprions L. Moroder Chalcogen-Analogs of Amino Acids. Their Use in Losson, R. X-Ray Crystallographic and Folding Studies of KRAB Zinc Finger Proteins and Nuclear Receptors: Peptides and Proteins A Possible Cross-talk Betz, M. Miiller-Hill, B. One Century of Protein Crystallography: Reflections and a Modest Proposal The Phycobiliproteins Scherrer, K. Braun, V. The Arolla Workshop — Some of Its History Avoidance of Iron Toxicity through Regulation of Bacterial Iron Transport Felix Hoppe-Seyler Lecture 1997 Briviba, K., L.-O. Klotz and H. Sies Zinkernagel, R.M. Toxic and Signaling Effects of Photochemically or Protective Antibody Responses against Viruses.... 725 Chemically Generated Singlet Oxygen in Biological Systems Reviews Cadet, J., M. Berger, T. Douki, B. Morin, S. Raoul, Alcedo, J. and M. Noll J.-L. Ravanat and S. Spinelli Hedgehog and Its Patched-Smoothened Receptor Effects of UV and Visible Radiation on DNA - Final Complex: A Novel Signalling Mechanism at the Cell Base Damage Cazzulo, J.J., V. Stoka and V. Turk Amano, N., Y. Ohfuku and M. Suzuki Cruzipain, the Major Cysteine Proteinase from the Genomes and DNA Conformation Protozoan Parasite Trypanosoma cruzi 1542 Contents Volume 378, 1997 Chattopadhyay, N., P.M. Vassilev and E.M. Brown Nuclear and Non-Nuclear Targets of Genotoxic Caicium-Sensing Receptor: Roles in and beyond Agents in the Induction of Gene Expression. Shared Systemic Calcium Homeostasis Principles in Yeast, Rodents, Man and Plants Chersi, A., F. Di Modugno and L. Rosano’ Hindges, R. and U. Hiibscher Aims and Limitations in the Use of Antipeptide DNA Polymerase 8, an Essential Enzyme for DNA Antibodies in Molecular Biology Transactions Cooper, A.J.L. and B.S. Kristal Hug, H. Multiple Roles of Glutathione in the Central Fas-Mediated Apoptosis in Tumor Formation and Nervous System Defense Creighton, T.E. Humm, A., E. Fritsche and S. Steinbacher Protein Folding Coupled to Disulphide Bond Structure and Reaction Mechanism of Formation L-Arginine:Glycine Amidinotransferase Dornburg, R. Ito, K. and S. Kawanishi From the Natural Evolution to the Genetic Site-Specific DNA Damage Induced by UVA Manipulation of the Host-Range of Radiation in the Presence of Endogenous Retroviruses Photosensitizer Escher, C.-L. and F. Widmer Keppler, D., |. Leier and G. Jedlitschky Lipid Mobilization and Gluconeogenesis in Plants: Transport of Glutathione Conjugates and Do Glyoxylate Cycle Enzyme Activities Constitute Glucuronides by the Multidrug Resistance Proteins a Real Cycle? A Hypothesis MRP1 and MRP2 Freist, W., D.H. Gauss, M. Ibba and D. Sdll Nagase, H. Glutaminyl-tRNA Synthetase Activation Mechanisms of Matrix Metalloproteinases Freist, W., D. H. Gauss, D. S6ll and J. Lapointe Glutamyl-tRNA Synthetase Neddermann, P., L. Tomei, C. Steinkiihler, P. Gallinari, A. Tramontano and R. De Francesco Geiselmann, J. The Nonstructural Proteins of the Hepatitis C Virus: The Role of DNA Conformation in Transcriptional Structure and Functions Initiation and Activation in Escherichia coli Neuefeind, T., P. Reinemer and B. Bieseler Goldberg, A.L., T.N. Akopian, A.F. Kisselev, D.H. Lee Plant Glutathione S-Transferases and Herbicide and M. Rohrwild Detoxification New Insights into the Mechanisms and Importance of the Proteasome in Intracellular Protein Pieters, J. Degradation MHC Class || Compartments: Specialized Organelles of the Endocytic Pathway in Antigen Presenting Graw, J. The Crystallins: Genes, Proteins and Diseases Piette, J., B. Piret, G. Bonizzi, S. Schoonbroodt, Grether-Beck, S., R. Buettner and J. Krutmann M.-P. Merville, S. Legrand-Poels and V. Bours Ultraviolet A Radiation-Induced Expression of Multiple Redox Regulation in NF-«B Transcription Human Genes: Molecular and Photobiological Factor Activation Mechanisms Riechmann, J.L. and E.M. Meyerowitz Habenicht, A. MADS Domain Proteins in Plant Development The Non-Phosphorylating Glyceraldehyde-3- Phosphate Dehydrogenase: Biochemistry, Scharffetter-Kochanek, K., M. Wlaschek, Structure, Occurrence and Evolution P. Brenneisen, M. Schauen, R. Blaudschun and J. Wenk Herrlich, P., C. Blattner, A. Knebel, K. Bender and UV-induced Reactive Oxygen Species in H. J. Rahmsdorf Photocarcinogenesis and Photoaging Contents Volume 378, 1997 Shore, D. Hagmann, M. Telomere Length Regulation: Getting the Measure RAGged Repair: What's New in V(D)J of Chromosome Ends Recombination Spada, S., C. Krebber and A. Pliickthun Honda, A. and A. Ishihama Selectively Infective Phages (SIP) The Molecular Anatomy of Influenza Virus RNA Polymerase Thiele, J. J., M. Podda and L. Packer Tropospheric Ozone: An Emerging Environmental Lai, M.M.C. Stress to Skin RNA-Protein Interactions in the Regulation of Coronavirus RNA Replication and Transcription. ... Turk, B., V. Turk and D. Turk Structural and Functional Aspects of Papain-Like Neuefeind, T., A. Bergner, F. Schneider, Cysteine Proteinases and Their Protein A. Messerschmidt and J. Knablein Inhibitors The Suitability of TagBr,2°* for Phasing in Protein Crystallography Valenta, R., S. Flicker, P.-B. Eibensteiner, P. Steinberger, S. Laffer, C. Dolecek and D. Kraft Steenken, S. Recombinant Allergen-Specific Antibody Fragments: Electron Transfer in DNA? Competition by Ultra-Fast Tools for Diagnosis, Prevention and Therapy of Type | PT IIE 5 65 boc ow bis kick meanncce sueesun 1293 Allergy van Veen, H.W. and W.N. Konings Drug Efflux Proteins in Multidrug Resistant Research Articles Bacteria Altschmied, J., L. Ditzel and M. Schartl Ventura, S., FX. Gomis-Ruth, A. Puigserver, F. X. Avilés Demethylation of the Xmrk Oncogene Promoter and J. Vendrell in Melanoma Cells of Xiphophorus Pancreatic Procarboxypeptidases: Oligomeric Structures and Activation Processes Revisited Arini, A., M. P. Keller and W. Arber An Antisense RNA in IS30 Regulates the Verbeek, M.M., D.J. Ruiter and R.M.W. de Waal Translational Expression of the Transposase The Role of Amyloid in the Pathogenesis of Alzheimers’s Disease Arnold, D., W. Keilholz, H. Schild, T. Dumrese, S. Stefanovic and H.-G. Rammensee Wenger, R.H. and M. Gassmann Evolutionary Conserved Cathepsin E Substrate Oxygen(es) and the Hypoxia-Inducible Factor-1.... 609 Specificity as Defined by N-Terminal and C-Terminal Sequencing of Peptide Pools Arts, G.-J., L. Engimeier and |.W. Mattaj Minireviews Energy-and Temperature-Dependent /n Vitro Blickling, S. and J. Knablein Export of RNA from Synthesis Nuclei Feedback Inhibition of Dihydrodipicolinate Synthase Enzymes by L-Lysine Balboni, G., R. Guerrini, S. Salvadori, R. Tomatis, S. D. Bryant, C. Bianchi, M. Attila and L. H. Lazarus De, B.P., T. Das and A.K. Banerjee Opioid Diketopiperazines: Synthesis and Activity Role of Cellular Kinases in the Gene Expression of of a Prototypic Class of Opioid Antagonists Nonsegmented Negative Strand RNA Viruses Beaucamp, N., H. Schurig and R. Jaenicke Eklund, H., M. Eriksson, U. Uhlin, P. Nordlund and The PGK-TIM Fusion Protein from Thermotoga D. Logan maritima and |ts Constituent Parts Are Intrinsically Ribonucleotide Reductase — Structural Studies of a Stable and Fold Independently Radical Enzyme Bergner, A., T. Muta, S. lwanaga, H.-G. Beisel, Gentil, A., F. Le Page and A. Sarasin R. Delotto and W. Bode The Consequence of Translesional Replication Horseshoe Crab Coagulogen Is an Invertebrate of Unique UV-induced Photoproducts Protein with a Nerve Growth Factor-Like Domain... 283 1544 Contents Volume 378, 1997 Boehm, M. and P. Résch De Frutos, T., J. Martin-Nieto and A. Villalobo Expression in Escherichia coli, Purification, and Phosphorylation of Calmodulin by Permeabilized Spectroscopic Characterization of Two Mutant Fibroblasts Overexpressing the Human Epidermal Bet v 1 Proteins Growth Factor Receptor Diedrich, T., U. Firstenau and W. Knepel Bonnycastle, L.L.C., K.L. Brown, J. Tang and Glucagon Gene G3 Enhancer: Evidence that Activity J.K. Scott Depends on Combination of an Islet-Specific Factor Assaying Phage-Borne Peptides by Phage Capture and a Winged Helix Protein on Fibrinogen or Streptavidin Ditzel, L., D. Stock and J. Lowe Breek, C.K.D., D. Speijer, H.D ekker, A.O. Muijsers Structural Investigation of Proteasome Inhibition... 239 and R. Benne Further Evidence for the Presence of Mitochondrially Emonard, H. and W. Hornebeck Encoded Subunits in Cytochrome c Oxidase of the Binding of 92 kDa and 72 kDa Progelatinases to Trypanosomatid Crithidia fasciculata Insoluble Elastin Modulates Their Proteolytic Activation Bryant, S.D., G. Balboni, R. Guerrini, S. Salvadori, Escherich, A., L. Ditzel, H.-J. Musiol, M. Groll, R. Tomatis and L.H. Lazarus R. Huber and L. Moroder Opioid Diketopiperazines: Refinement of the 6 Synthesis, Kinetic Characterization and X-Ray Opioid Antagonist Pharmacophore Analysis of Peptide Aldehydes as Inhibitors of the 20S Proteasomes from Thermoplasma acidophilum Birgle, M., M. Koppitz, C. Riemer, H. Kessler, B. and Saccharomyces cerevisiae K6nig, U. H. Weidle, J. Kellermann, F. Lottspeich, H. Graeff, M. Schmitt, L. Goretzki, U. Reuning, Fischer-Schliebs, E., E. Ball, E. Berndt, O. Wilhelm and V. Magdolen E. Besemfeider-Butz, M.L. Binzel, M. Drobny, D. Inhibition of the Interaction of Urokinase-Type Mihlenhoff, M.L. Miller, K. Rakowski and Plasminogen Activator (uPA) with Its Receptor R. Ratajczak (uPAR) by Synthetic Peptides Differential Immunological Cross-Reactions with Antisera against the V-ATPase of Kalanchoé Bunik, V., H. Follmann and H. Bisswanger daigremontiana Reveal Structural Differences of Activation of Mitochondrial 2-Oxoacid V-ATPase Subunits of Different Plant Species Dehydrogenases by Thioredoxin Fraser-L’Hostis, C., F. Defrise-Quertain, D. Coral and J. Deshusses Bureik, M., A. Jungbluth, R. Drescher and P. Wagner Regulation of the Intracellular pH in the Protozoan Human p53 Restores DNA Synthesis Control in Parasite Trypanosoma brucei brucei Fission Yeast Fritsch, C., C. Abels, A. E. Goetz, W. Stahl, K. Bolsen, Cavarra, E., PA. Martorana, S. Cortese, F. Gambelli, T. Ruzicka, G. Goerz and H. Sies P. Di Simplicio and G. Lungarella Porphyrins Preferentially Accumulate in a Melanoma Neutrophils in Beige Mice Secrete Normal Amounts Following Intravenous Injection of 5-Aminolevulinic of Cathepsin G and a 46 kDa Latent Form of Elastase that Can Be Activated Extracellularly by Proteolytic Activity Galli, |., M. Uchiyama and T.S.F. Wang DNA Replication and Order of Cell Cycle Events: Chernov, A.V., P. Volimayr, J. Walter and T.A. Trautner Masc2, a C5-DNA-Methyltransferase from Ascobolus Gast, F.U., T. Brinkmann, U. Pieper, T. Kruger, immersus with Similarity to Methyltransferases of M. Noyer-Weidner and A. Pingoud Higher Organisms The Recognition of Methylated DNA by the GTP- Dependent Restriction Endonuclease McrBC Cinkaya, |., W. Buckel, M. Medina, C. Gomez-Moreno Resides in the N-Terminal Domain of McrB and R. Cammack Electron-Nuclear Double Resonance Spectroscopy Gaunitz, F.,C. Gaunitz, M. Papke and R. Gebhardt Investigation of 4-Hydroxybutyryl-CoA Dehydratase Cis-Regulatory Sequences from the First Intron of from Clostridium aminobutyricum: Comparison with the Rat Glutamine Synthetase Gene Are Involved in Other Flavin Radical Enzymes Hepatocyte Specific Expression of the Enzyme .... Contents Volume 378,1997 1545 Geng, J.-P., C.-H. Cheng and F. J. Castellino Kostoulas, G., D. Hérier, A. Naggi, B. Casu and The Functions of the First Epidermal Growth Factor A. Baici Homology Region of Human Protein C as Revealed Electrostatic Interactions between Human Leukocyte by a Charge-to-Alanine Scanning Mutagenesis Elastase and Sulfated Glycosaminoglycans: Investigation Physiological Implications Gronwald, W., D. Schomburg, W. Tegge and V. Wray Kroll Kristensen, A., C. Schou and P. Roepstorff Assessment by 'H NMR Spectroscopy of the Determination of Isoforms, N-Linked Glycan Structural Behaviour of Human Parathyroid- Structure and Disulfide Bond Linkages of the Hormone-Related Protein (1-34) and Its Close Major Cat Allergen Fel d 1 by a Mass Spectrometric Relationship with the N-Terminal Fragments of Approach Human Parathyroid Hormone in Solution Kulms, D., G. Schafer and U. Hahn Hentges, A. and E. Bause Overproduction of Sac7d and Sac7e Reveals only Affinity Purification and Characterization of Sac7e to Be a DNA-Binding Protein with Glucosidase II from Pig Liver Ribonuclease Activity from the Extremophilic Archaeon Sulfolobus acidocaldarius lannolo, G., O. Minenkova, S. Gonfloni, L. Castagnoli and G. Cesareni Kurth, D., J. Neumann, K. Demleitner, J. Hildmann, Construction, Exploitation and Evolution of a New M. Mehlig, C. Scheicher, U. Wendling, D. Sun and Peptide Library Displayed at High Density by Fusion K. Reske to the Major Coat Protein of Filamentous Phage.... 517 Full Length cDNA of Rat RT1.DMa and RT1.DMb and Expression of RT1.DM Genes in Dendritic Kawabata, S., T. Saito, K. Saeki, N. Okino, and Langerhans Cells A. Mizutani, Y. Toh and S. lwanaga cDNA Cloning, Tissue Distribution, and Subcellular Landt, O., J. Thélke, H.-P. Grunert, W. Saenger and Localization of Horseshoe Crab Big Defensin U. Hahn Ribonuclease T1 Is Active when Both Catalytic Keller, H., PR. Devchand, M. Perroud and W. Wahii Histidines Are Replaced by Aspartate PPARa Structure-Function Relationships Derived from Species-Specific Differences in Lauvrak, V., O. H. Brekke, ©. Ihle and B. H. Lindquist Responsiveness to Hypolipidemic Agents Identification and Characterisation of C1q-Binding Phage Displayed Peptides Kessler, R., N.B. Laursen, T. Trib, M.B. Kalousek and R. Klemenz Linn, H., K.S. Ermekova, S. Rentschier, A.B. Sparks, Cooperative Interactions of AP-1 and Basic Helix- B.K. Kay and M. Sudol Loop-Helix Transcription Factors Regulate T1 Gene Using Molecular Repertoires to Identify High-Affinity Expression Peptide Ligands of the WW Domain of Human and Mouse YAP Kido, H., Y. Beppu, K. Sakai and T. Towatari Molecular Basis of Proteolytic Activation of Sendai Logemann, E., S. Reinold, |.£. Somssich and Virus Infection and the Defensive Compounds for K. Hahlbrock Infection A Novel Type of Pathogen Defense-Related Kilger, C. and S. Paabo Cinnamyl Alcohol Dehydrogenase Direct Exponential Amplification and Sequencing (DEXAS) of Genomic DNA Lopata, M., D. Schlieper, B. von Wilcken-Bergmann and B. Miller-Hill Knablein, J., H. Dobbek, S. Ehlert and F. Schneider ALethal Mutant of the Catabolite Gene Activator Isolation, Cloning, Sequence Analysis and X-Ray Protein CAP of Escherichia coli Structure of Dimethy! Sulfoxide/Trimethylamine N-Oxide Reductase from Rhodobacter Lu, B., Q. Liand W.-Y. Liu capsulatus Dynamic Structure of the Sarcin/Ricin Domain in Rat 28S Ribosomal RNA Investigated by Hybridization Kolkenbrock, H., A. Hecker-Kia, D. Orgel, N. Ulbrich with Oligodeoxynucleotide and H. Will Activation of Progelatinase A and Progelatinase Luschnig, C. and A. Bachmair A/TIMP-2 Complex by Membrane Type 2-Matrix RNA Packaging of Yeast Retrotransposon Ty1 in Metalloproteinase the Heterologous Host, Escherichia coli 1546 Contents Volume 378, 1997 Lyss, G., T.J. Schmidt, |. Merfort and H. Pahl Oberosler, P. and W. Nellen Helenalin, an Anti-Inflammatory Sesquiterpene Functional Activity and Developmental Regulation Lactone from Arnica, Selectively Inhibits of DdRBP1, a RNA Binding Protein in Dictyostelium Transcription Factor NF-«B discoideum Macheroux, P., C. Sanner, H. Biittner, V. Kieweg, Ohlsson, S., B. Tufvesson, A. Polling and K. Ohisson H. Riterjans and S. Ghisla Distribution of the Secretory Leucocyte Proteinase Medium-Chain Acyl CoA Dehydrogenase: Inhibitor in Human Articular Cartilage Evidence for Phosphorylation Orlandi, R., C. Formantici, S. Ménard, C. M. Boyer, Marienfeld, J.R., M. Unseld, P. Brandt and J. R. Wiener and M. |. Colnaghi A. Brennicke A Linear Region of a Monoclonal Antibody Mosaic Open Reading Frames in the Arabidopsis Conformational Epitope Mapped on p185"*** thaliana Mitochondrial Genome Oncoprotein Messerschmidt, A., L. Prade and R. Wever Orru, S., A. Scaloni, M. Giannattasio, K. Urech, Implications for the Catalytic Mechanism of the P. Pucci and G. Schaller Vanadium-Containing Enzyme Chloroperoxidase Amino Acid Sequence, S-S Bridge Arrangement and from the Fungus Curvularia inaequalis by X-Ray Distribution in Plant Tissue of Thionins from Viscum Structures of the Native and Peroxide Form Meyer, W., U. Bomer and E. Pratje Patzel, V., J. zu Putlitz, S. Wieland, H.E. Blum and Mitochondrial Inner Membrane Bound Pet1402 G. Sezakiel Protein Is Rapidly Imported into Mitochondria and Theoretical and Experimental Selection Parameters Affects the Integrity of the Cytochrome Oxidase for HBV-Directed Antisense RNA Are Related to and Ubiquinol-Cytochrome c Oxidoreductase Increased RNA-RNA Annealing Complexes Peters, K., H.-J. Hinz and G. Cesareni Milkereit, P., P. Schultz and H. Tschochner Introduction of a Proline Residue into Position 31 Resolution of RNA Polymerase | into Dimers and of the Loop of the Dimeric 4-a-Helical Protein ROP Monomers and Their Function in Transcription Causes a Drastic Destabilization Moosmann, P., O. Georgiev, H.-J. Thiesen, Poethke, R., W. Hartig, G. Brickner, K. Felgenhauer M. Hagmann and W. Schaffner and M. Mader Silencing of RNA Polymerases II and IIl-Dependent Characterization of Monoclonal and Polyclonal Transcription by the KRAB Protein Domain of KOX1, Antibodies to Human Choline Acetyltransferase and a Krippel-Type Zinc Finger Factor Epitope Analysis Mueller, H., R. Liu, F. David and U. Eppenberger Poloni, F. M., Castagna, F. Felici and M. Cianfriglia Selective Modulation of Protein Kinase A and Protein A New Immunohistochemical Methodology for the Kinase C Activities in Epidermal Growth Factor Specific Detection of MDR-1-P-Glycoprotein in (EGF)-Stimulated MCF-7 Breast Cancer Cells 1023 Human Tissues Based on Phage-Displayed Peptides Mimicking the MM4.17 Epitope Miller, J. C. D., E. Graf von Roedern, F. Grams, H. Nagase and L. Moroder Potempa, J., R. Pike and J. Travis Non-Peptide Cysteine Derivatives as Inhibitors of Titration and Mapping of the Active Site of Cysteine Matrix Metalloproteinases Proteinases from Porphyromonas gingivalis (Gingipains) Using Peptidyl Chloromethanes Napiwotzki, J., K. Shinzawa-ltoh, S. Yoshikawa and B. Kadenbach RieBland, R. and R. Jaenicke ATP and ADP Bind to Cytochrome c Oxidase and Determination of the Regulatory Disulfide Bonds Regulate Its Activity of NADP-Dependent Malate Dehydrogenase from Pisum sativum by Site-Directed Mutagenesis Nogoceke, E., D.U. Gommel, M. KieB, H.M. Kalisz and L. Flohé Rother, K. |., O. K. Clay, J.-P. Bourquin, J. Silke and A Unique Cascade of Oxidoreductases Catalyses W. Schaffner Trypanothione-Mediated Peroxide Metabolism in Long Non-Stop Reading Frames on the Antisense Crithidia fasciculata Strand of Heat Shock Protein 70 Genes and Prion Contents Volume 378,1997 1547 Protein (PrP) Genes Are Conserved between Identification of HCV Core Mimotopes: Improved Methods for the Selection and Use of Disease-Related Phage-Displayed Peptides Runge, D., D.M. Runge, W.C. Bowen, J. Locker and G.K. Michalopoulos Tanaka, A.S., M.U. Sampaio, S. Marangoni, Matrix Induced Re-Differentiation of Cultured Rat B. de Oliveira, J.C. Novello, M.L.V. Oliva, E. Fink Hepatocytes and Changes of CCAAT/Enhancer and C.A.M. Sampaio Binding Proteins Purification and Primary Structure Determination of a Bowman-Birk Trypsin Inhibitor from Torresea Sakurai, M., B. Watanabe, S. Nagata and M. Ichikawa cearensis Seeds Identification of Atrial-Specific Myosin Heavy Chain in Cardiac Muscle of Adult Chickens Terry ,T.D., P. Malik and R.N. Perham Accessibility of Peptides Displayed on Saris, N.-E.L. Filamentous Bacteriophage Virions: Susceptibility On the Mechanism of Rebounding of Calcium in to Proteinases Liver Mitochondria Thielking, V., S. Du Bois, R. Eritja and W. Guschibauer Schenkels, L.C.P.M., E. Walgreen-Weterings, Dam Methyltransferase from Escherichia coli: Kinetic L.C.J.M. Oomen, J.G.M. Bolscher, E.C.1. Veerman Studies Using Modified DNA Oligomers: and A.V. Nieuw Amerongen Nonmethylated Substrates In Vivo Binding of the Salivary Glycoprotein EP-GP (identical to GCDFP-15) to Oral and Non-Oral Van Kuilenburg, A.B.P., H. Van Lenthe, R.J.A. Wanders Bacteria. Detection and Identification of EP-GP and A.H. Van Gennip Binding Species Subcellular Localization of Dihydropyrimidine Dehydrogenase Schmid H., M. Koop, S. Utermann, L. Lambacher, P. Mayer and L. Schaefer Warth, R., P.-A. Briand and D. Picard Specific Catalytic Activity of Cathepsin S in Functional Analysis of the Yeast 40 kDa Cyclophilin Comparison to Cathepsins B and L along the Rat Cyp40 and Its Role for Viability and Steroid Receptor Nephron Regulation Schmidlin, A., H. Kalbacher and H. Wiesinger Winter, B., |. Kautzner, O-G. Issinger and Presence of Argininosuccinate Synthetase in Glial H.-H. Arnold Cells as Revealed by Peptide-Specific Antisera .. .. Two Putative Protein Kinase CK2 Phosphorylation Sites Are Important for Myf-5 Activity Schriever, C., G. Breithardt and A. Schmidt Undersulfation of Proteoheparan Sulfate Stimulates Wu, X., W. Liu, L. Xu and M. Li the Expression of Basic Fibroblast Growth Factor Topography of Ribosomes and Initiation Complexes and Protein Synthesis but Suppresses Replication from Rat Liver Revealed by Atomic Force of Coronary Smooth Muscle Cells Microscopy Sheng, G., E. Harris, C. Bertuccioli and C. Despian Yilmaz, O., S. Celik and N. Dilsiz Modular Organization of Pax/Homeodomain Proteins in Transcriptional Regulation Influences of Intraperitoneally and Dietary Administered Vitamin E and Selenium on the Lipid Steinbacher, S., S. Miller, U. Baxa, A. Weintraub and Composition in Reproductive Organs of Male R. Seckler Animals Interaction of Salmonella Phage P22 with Its O-Antigen Receptor Studied by X-Ray Zeidler, M.P. and M. Mlodzik Crystallography six-banded, a Novel Drosophila Gene, Is Expressed in 6 Segmental Stripes during Embryonic Swart, G.W.M., J.J.M. van Groningen, F. van Ruissen, Development and in the Eye imaginal Disc M. Bergers and J. Schalkwijk Transcription Factor C/EBPa: Novel Sites of Zimmermann, C., E. Guhl and A. Graessmann Expression and Cloning of the Human Gene Mouse DNA Methyitransferase (MTase) Deletion Mutants that Retain the Catalytic Domain Display Tafi, R., R. Bandi, C. Prezzi, M.U. Mondelli, R. Cortese, neither De Novo nor Maintenance Methylation P. Monaci and A. Nicosia Activity In Vivo 1548 Contents Volume 378, 1997 Zoche, M., M. Beyermann and K.-W. Koch lliopoulos, |., |. Tér6k and B.M. Mechler Introduction of a Phosphate at Serine”*' of the The DnaJ60 Gene of Drosophila melanogaster Calmodulin-Binding Domain of the Neuronal Encodes a New Member of the DnaJ Family of Nitric Oxide Synthase (NOS-I) Prevents Binding of Proteins Calmodulin Kisselev, A.F., R. Mentele and K. von der Helm Zou, M., C. Martin and V. Ullrich Cleavage of the Complement System C3 Tyrosine Nitration as a Mechanism of Selective Component by HIV-1 Proteinase Inactivation of Prostacyclin Synthase by Peroxynitrite Knablein, J., H. Dobbek and F. Schneider Organization of the DMSO Respiratory Operon of Zweimiller, M., S. Antus, T. Kovacs and Rhodobacter capsulatus and Its Consequences for J. Sonnenbichler Homologous Expression of DUSOR/TMAOR Biotransformation of the Fungal Toxin Fomannoxin by Conifer Cell Cultures Laboissiére, M.C.A., S.L. Sturley and R.T. Raines Protein Disulfide Isomerase in Spore Germination and Cell Division Short Communications Macedo-Ribeiro, S., B. Darimont and R. Sterner Auerbach, G., U. Jacob, M. Grattinger, H. Schurig and Structural Features Correlated with the Extreme R. Jaenicke Thermostability of 1[4Fe-4S] Ferredoxin from the Crystallographic Analysis of Phosphoglycerate Hyperthermophilic Bacterium Thermotoga Kinase from the Hyperthermophilic Bacterium maritima Thermotoga maritima Masat, L. and M. Wabl Bordusa, F., D. Ullmann and H.-D. Jakubke Inducible Expression of the 81 Subunit of the Subsite Specificity Studies on the Unusual Cysteine Sodium Pump Protease Clostripain: Charged Residues in the P; Position Indicate a Narrow Subsite Region Mittag, M. and H. Waltenberger In Vitro Mutagenesis of Binding Site Elements Clausen, T., B. Laber and A. Messerschmidt for the Clock-Controlled Proteins CCTR and Mode of Action of Cystathionine B-Lyase Chlamy 1 Di Mascio, P., K. Briviba, S.T. Sasaki, L.H. Catalani, Miller, E., H. Hegewald, R. Klinger and H. Frunder M.H.G. Medeiros, E.J.H. Bechara and H. Sies Dependence on Intracellular Ca** of Mass and The Reaction of Peroxynitrite with tert-Butyl Turnover of Phosphoinositides and Phosphatidate Hydroperoxide Produces Singlet Molecular in Human Erythrocytes Nikogosyan, D. N. and H. Gérner Ehlers, C., F. Kopp and B. Dahimann Photolysis (193 nm) of Aliphatic Dipeptides in Screening for Molecules Interacting with Aqueous Solution Proteasomes in Thermoplasma acidophilum Oduncu, F., G. Krause, T. R6hnisch, B. Emmerich Finken-Eigen, M., S. Miller and K. K6hrer and K. Pachmann Cloning and Characterization of a Dominant- Complementary Anchor PCR of Rearranged Negative vps7 Allele of the Yeast Saccharomyces Variable T-Cell Receptor B-Chain cDNA Regions ... 1211 cerevisiae Pietrowski, D. and J. Graw Fitton, H.L., R.N. Pike, R.W. Carrell and W.S.W. Chang Autokinase Activity of a-Crystallin Inhibits Its Mechanisms of Antithrombin Polymerisation and Specific Interaction with the DOTIS Element in the Heparin Activation Probed by the Insertion of Murine yD/E/F-Crystallin Promoter /n Vitro Synthetic Reactive Loop Peptides Piubelli, L., G. Zanetti and H.R. Bosshard Haensler, M., U. Hahn and H.-D. Jakubke Recombinant Wild-Type and Mutant Complexes of Reverse Action of Ribonuclease T1 in Frozen Ferredoxin and Ferredoxin:NADP* Reductase Aqueous Systems Studied by Isothermal Titration Calorimetry Contents Volume 378, 1997 1549 Prade, L., P. Hof and B. Bieseler Polymerase II through a Conserved Interaction Dimer Interface of Glutathione S-Transferase from Arabidopsis thaliana: \nfluence of the G-Site Architecture on the Dimer Interface and Todorovska, E. G., A. Atanassova, L. S. Antonov Implications for Classification and K. P. Dudov Studies on the Mouse rpL32 Pseudogene Family: Redd, A.J., S.L. Clifford and M. Stoneking Features of a New Member Multiplex DNA Typing of Short-Tandem-Repeat Loci on the Y Chromosome Valentini, G., A. Mattevi, D. Barilla’, A. Galizzi and M.L. Speranza Sadoul, K., A. Berger, H. Niemann, R. Regazzi, Recombinant Pyruvate Kinase Type | from Escherichia S. Catsicas and P.A. Halban coli: Overproduction and Revised C-Terminus of the SNAP-25 Can Self-Associate to Form a Polypeptide Disulfide-Linked Complex Zerovnik, E., N. Cimerman, J. Kos, V. Turk and Seol, J.H., J.-A. Kwon, S.J. Yoo, H.S. Kim, M.-S. Kang K. Lohner and C.H. Chung Thermal Denaturation of Human Cystatin C and Site-Directed Mutagenesis of the Cys Residues Two of Its Variants; Comparison to Chicken in CIpA, the ATPase Component of Protease Cystatin Ti (CIpAP) in Escherichia coli Suchanek, B., P.H. Seeburg and R. Sprengel Acknowledgement Tissue Specific Control Regions of the N-Methyl- D-Aspartate Receptor Subunit NR2C Promoter .... Author Index Tanner, S., |. Stagljar, O. Georgiev, W. Schaffner and J.-P. Bourquin A Novel SR-Related Protein Specifically Interacts with the Carboxy-Terminal Domain (CTD) of RNA Subject Index