LWBK271-FM_i-x.qxd 1/29/09 1:58 PM Page i LWBK271-C01_01-08.qxd Basic and Bedside Electrocardiography LWBK271-FM_i-x.qxd 1/29/09 1:58 PM Page ii LWBK271-C01_01-08.qxd LWBK271-FM_i-x.qxd 1/29/09 1:58 PM Page iii LWBK271-C01_01-08.qxd Basic and Bedside Electrocardiography Romulo F.Baltazar,MD,FACC Director,Noninvasive Cardiology Sinai Hospital of Baltimore Assistant Professor,Medicine Johns Hopkins University Baltimore,Maryland LWBK271-FM_i-x.qxd 1/29/09 1:58 PM Page iv LWBK271-C01_01-08.qxd Acquisitions Editor: Frances Destefano Managing Editor: Leanne McMillan Marketing Manager: Kimberly Schonberger Production Editor: Beth Martz Design Coordinator: Stephen Druding Compositor: Aptara,Inc. 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To request permission, please contact Lippincott Williams & Wilkins at 530 Walnut Street,Philadelphia,PA 19106,via email at [email protected],or via website at lww.com (products and services). 9 8 7 6 5 4 3 2 1 Library ofCongress Cataloging-in-Publication Data Baltazar,Romulo F. Basic and bedside electrocardiography / Romulo F.Baltazar. p.;cm. Includes index. ISBN-13:978-0-7817-8804-5 ISBN-10:0-7817-8804-8 1. Electrocardiography. I.Title. [DNLM: 1. Electrocardiography. 2. Heart Diseases—diagnosis. 3. Heart Diseases—therapy. 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LWBK271-FM_i-x.qxd 1/29/09 1:58 PM Page vi LWBK271-C01_01-08.qxd LWBK271-FM_i-x.qxd 1/29/09 1:58 PM Page vii LWBK271-C01_01-08.qxd Preface More than 100 years since its introduction,electrocar- Hartman, Kevin Hayes, Khawaja Farook, Jason Javillo, diography continues to provide invaluable clinical Jennifer Morales, Ubadullah Sharief, Ledys de Marsico, information.Even with the development of modern and Celian Valero,Samarina Ahmad,Kweku Hayford,Haritha more expensive technologies,its significance has not de- Pendli,Maya Morrison,and many others.I am also grate- clined.To the contrary,its clinical application continues ful to Kittane Vishnupriya for his very helpful comments to expand,and presently,it is the most utilized diagnostic and for the ECG that he painstakingly obtained to illus- modality in the whole practice ofmedicine.In the hospi- trate the significance ofthe posterior leads in the diagno- tal setting,it is routinely used to monitor both cardiac and sis of posterolateral myocardial infarction when he was a noncardiac patients, especially in acute care units and coronary care resident.I am also grateful to Drs.Gabriela during the performance of various cardiac and noncar- Szabo,Ameena Etherington, and Soma Sengupta for re- diac procedures. Thus, the information provided by the viewing chapters in the book,and Laura Baldwin,our su- electrocardiogram should be standard knowledge for perb cardiology technician,who has taught me how to re- every medical and paramedical professional who is in- trieve and record electrocardiograms from our archives. volved with patient care. I am also grateful to Dr.Morton Mower who has been This book is purposely written in a format that will my mentor since I was a resident.His suggestions for im- assist the beginner, including medical students, nurses, proving the book are greatly appreciated.I would also like and paramedical professionals, in understanding basic to express my deep appreciation to Dr.Steven Gambert, electrocardiography. It is also intended for interns, resi- Chief of the Department of Medicine, Johns Hopkins dents,physician assistants,fellows,anesthesiologists,and University/Sinai Hospital Program in Internal Medicine, clinical cardiologists by including standard of care treat- for his support and encouragement and for his enthusi- ment ofpatients with electrocardiographic abnormalities asm in having this book published. based on the most recent practice guidelines when guide- Finally,I am grateful to my daughter,Cristina,who is lines are available. Thus, the book is a combination of instrumental in teaching me how to use the computer in both basic and bedside electrocardiography. the preparation ofthis book and my son Romulo,Jr who The book integrates the comments and suggestions of decided on Radiology as his specialty, for his comments many interns, residents, and attending physicians to and suggestions for simplifying some of the chapters, whom I owe a great deal ofgratitude.I would like to thank especially those dealing with Basic Electrocardiography. Drs. Miruais Hamed, Paul Aoun, Eileen Zingman, Olga Szalasny,Katja Vassiliades,Manish Arora,Onyi Onuoha, Romulo F.Baltazar,MD,FACC Brandon Togioka, Darshana Purohit, Ranjani Ra- Director,Noninvasive Cardiology,Department ofMedicine manathan,Binu Matthew,Paolo Caimi,Mulugeta Fissha, Johns Hopkins University/Sinai Hospital Program in Hany Bashandy, Cindy Huang, Suzan Fattohy, Rachel Internal Medicine vii LWBK271-FM_i-x.qxd 1/29/09 1:58 PM Page viii LWBK271-C01_01-08.qxd LWBK271-FM_i-x.qxd 1/29/09 1:58 PM Page ix LWBK271-C01_01-08.qxd Contents Preface vii 1 Basic Anatomy and Electrophysiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2 Basic Electrocardiography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 3 The Lead System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 4 The Electrical Axis and Cardiac Rotation . . . . . . . . . . . . . . . . . . . . . . . . . 30 5 Heart Rate and Voltage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 6 Depolarization and Repolarization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 7 Chamber Enlargement and Hypertrophy . . . . . . . . . . . . . . . . . . . . . . . . . 62 8 Atrioventricular Block . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 9 Intraventricular Conduction Defect:Fascicular Block . . . . . . . . . . . . . . 112 10 Intraventricular Conduction Defect:Bundle Branch Block . . . . . . . . . . 120 11 Intraventricular Conduction Defect:Trifascicular Block . . . . . . . . . . . . 138 12 Sinus Node Dysfunction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 148 13 Premature Supraventricular Complexes . . . . . . . . . . . . . . . . . . . . . . . . . 167 14 Sinus Tachycardia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180 15 Supraventricular Tachycardia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 16 Supraventricular Tachycardia due to Reentry . . . . . . . . . . . . . . . . . . . . . 187 17 Supraventricular Tachycardia due to Altered Automaticity . . . . . . . . . . 211 18 Atrial Flutter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 233 19 Atrial Fibrillation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 246 20 Wolff-Parkinson-White Syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 262 21 Ventricular Arrhythmias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287 22 Wide Complex Tachycardia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310 23 Acute Coronary Syndrome:ST Elevation Myocardial Infarction . . . . . . 331 24 Acute Coronary Syndrome:Non-ST Elevation Myocardial Infarction and Unstable Angina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379 25 Electrolyte Abnormalities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 396 26 The ECG of Cardiac Pacemakers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 414 Appendix:Commonly Used Injectable Pharmacologic Agents . . . . . . . . . . . . . 435 Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449 ix LWBK271-FM_i-x.qxd 1/29/09 1:58 PM Page x LWBK271-C01_01-08.qxd