UNITY&FAITH,PEACE&PROGRESS NATIONAL GUIDELINES FOR INPATIENT MANAGEMENT OF SEVERE ACUTE MALNUTRITION IN INFANTS AND YOUNG CHILDREN IN NIGERIA FEDERAL MINISTRY OF HEALTH, NIGERIA FAMILY HEALTH DEPARTMENT, NUTRITION DIVISION FEBRUARY, 2016 UNITY&FAITH,PEACE&PROGRESS NATIONAL GUIDELINES FOR INPATIENT MANAGEMENT OF SEVERE ACUTE MALNUTRITION IN INFANTS AND YOUNG CHILDREN IN NIGERIA FEDERAL�MINISTRY�OF�HEALTH,�NIGERIA� FAMILY�HEALTH�DEPARTMENT,�NUTRITION�DIVISION FEBRUARY,�2016 NATIONAL GUIDELINES FOR INPATIENT MANAGEMENT OF SEVERE ACUTE MALNUTRITION IN INFANTS AND YOUNG CHILDREN IN NIGERIA Table of Contents Acknowledgements vi Foreword vii List of Contributors viii Acronyms and Abbreviations ix CHAPTER 1: Background 1 1.1. Severe Acute Malnutrition (SAM) in Nigeria 2 1.2. Integrated Management of Acute Malnutrition (IMAM) approach 3 CHAPTER 2: Assessment of severe acute malnutrition 5 2.1. Definition of severe acute malnutrition 6 2.2. Inpatient admission criteria 6 2.3. Nutritional Assessment 7 2.3.1. Measuring MUAC 7 2.3.2. Checking bilateral oedema and Grading 8 2.3.3. Measuring Weight 8 2.3.4. Measuring Length/Height 9 2.3.5. Determining Weight- for-Height/length Z-Score 10 2.4. Initial clinical assessment 12 2.5. Medical complications in patients with SAM 12 2.6. Appetite test 13 2.6.1. How to do Appetite Test 13 2.6.2. Interpretation of Appetite Test 14 CHAPTER 3: Principles of Inpatient care 15 3.1. Phases of Inpatient Care for Children 6-59m 16 3.1.1. Stabilization Phase 16 3.1.1.1 Dehydration in marasmic patients 17 3.1.1.2 Shock 23 3.1.1.3 Septic (Toxic) shock 24 3.1.1.4 Absent bowel sounds, gastric dilatation and intestinal splash with abdominal distension 26 3.1.1.5 Heart Failure 27 3.1.1.6 Correct electrolyte 29 3.1.1.7 Correct Severe Anaemia 30 3.1.1.8 Hypoglycemia 31 3.1.1.9 Hypothermia 33 3.1.1.10 Infection 34 3.1.1.11 Micronutrient deficiencies 35 3.1.1.12 Feeding including Breastfeeding 36 3.1.1.13 Addressing Associated Conditions 40 ii NATIONAL GUIDELINES FOR INPATIENT MANAGEMENT OF SEVERE ACUTE MALNUTRITION IN INFANTS AND YOUNG CHILDREN IN NIGERIA 3.1.2. Transition Phase 46 3.1.2.1. Catch-up Growth Feeding 46 3.1.3 Rehabilitation Phase 52 3.2 Infants <6months with SAM 54 CHAPTER 4: Organization of Inpatient Facility (IPF) 63 4.1. Admission ward 64 4.2. Roles of Service providers 64 4.2.1. Doctors 64 4.2.2. Nurses 65 4.2.3. Dietitians and Nutritionists 65 4.2.4. Pharmacist 65 4.2.5. Records Officer 65 4.2.6. Medical Social WorkersCommunity Health Extension workers/ Community Health Officers 65 4.3. Records 66 4.3.1. Malnutrition record books 66 4.3.2. Admission and monitoring charts 66 4.4. Medicines 66 4.4.1. Routine first line 66 4.4.2. Alternative and supplementary medicines 66 4.5. Equipment and supplies 67 4.5.1. Anthropometric tools 67 4.5.2. Kitchen equipment and supplies 67 4.5.3. Therapeutic foods and other materials 67 CHAPTER 5: Failure to respond to treatment 68 5.1. High Mortality 69 5.2. Low weight gain during rehabilitation phase 70 5.3. Re-feeding syndrome 72 CHAPTER 6: Transfer to Outpatient Therapeutic Program (OTP) 74 6.1. Transfer criteria for rehabilitation in OTP 75 6.2. Two way referral system 75 6.3. Follow-up at OTP 76 6.4. Discharge criteria 76 iii NATIONAL GUIDELINES FOR INPATIENT MANAGEMENT OF SEVERE ACUTE MALNUTRITION IN INFANTS AND YOUNG CHILDREN IN NIGERIA CHAPTER 7: Monitoring quality of care 77 7.1. Definition of terms 78 7.2. Performance indicators 81 7.3. Mortality audit 82 7.4. IPF Monthly reporting 82 7.5. Categories for report writing 83 7.6. IPF Supervision by relevant agents 84 List of Tables Table 1 Admission Criteria for inpatient care 6 Table 2 MUAC reading interpretation 7 Table 3 Grading of oedema 8 Table 4 Interpretation of weight for height Z-scores 11 Table 5 Medical Complications for admission into inpatient care 12 Table 6 Interpretation of Appetite test 14 Table 7 Vitamin A doses by age 36 Table 8 Amounts of F75 to give during Stabilization Phase 38 Table 9 Look up table for RUTF in Transition Phase per 24h 48 Table 10 Look up table for F-100 in Transition Phase per 24h 48 Table 11 Admission criteria for infants < 6 months 54 Table 12 Criteria for Failure-to-respond for In-Patients 69 Table 13 Case fatality rates 69 Table 14 Categorization of weight changes 70 Table 15 Admission and exit criteria 81 Table 16 SPHERE Indicators 82 List of Figures Figure 1 Care model for severe acute malnutrition 4 Figure 2 Bilateral pitting pedal oedema 8 Figure 3 Measuring the length of the child less than 87cm 9 Figure 4 Measuring the height of the child greater than 87cm 10 Figure 5 Determination of Weight for height Z –Scores using unisex table 11 Figure 6 Treatment of dehydration in marasmic children 20 Figure 7 Monitoring rehydration in Marasmic children 20 Figure 8 Algorithm of respiratory distress 29 Figure 9 Managing Anaemia 31 Figure 10 Feeding F-75 by mouth 39 Figure 11 Breastfeeding Infant 53 Figure 12 Supplementary suckling technique 57 iv NATIONAL GUIDELINES FOR INPATIENT MANAGEMENT OF SEVERE ACUTE MALNUTRITION IN INFANTS AND YOUNG CHILDREN IN NIGERIA Annexes 85 Annex 1 Anthropometric measurement techniques 86 Annex 2 Weight for length/Height Unisex Table 94 Annex 3 Recipes for F-75,F-100 and ReSoMal 98 Annex 4 Critical Care Pathway Chart 100 Annex 5 Weight loss and weight gain by 5% chart 101 Annex 6 Drug reference tables 102 Annex 7 RUTF specification 108 Annex 8 Daily Ward Feed chart 112 Annex 9 F-75 feed volumes for children 113 Annex 10 Multi- chart for monitoring progress 114 Annex 11 Inserting a Nasogastric tube RUTF ration chart 118 Annex 12 Simple toys for emotional and psychological stimulation 120 Annex 13 RUTF/F-100 ration chart 121 Annex 14 Supplementary Sucking technique milk volumes 123 Annex 15 IPF Record book 125 Annex 16 F-100 Dilute look- up table 126 Annex 17 Transfer form 127 Annex 18 IPF Monthly reporting form 128 Annex 19 IPF Supervisory checklist 129 v NATIONAL GUIDELINES FOR INPATIENT MANAGEMENT OF SEVERE ACUTE MALNUTRITION IN INFANTS AND YOUNG CHILDREN IN NIGERIA ACKNOWLEDGEMENT The Federal Ministry of Health is indebted to several Stakeholders for their concerted efforts in the development of this guideline. The process included series of consultative meetings and workshops in collaboration with relevant stakeholders in Nutrition on the review of various materials and experiences in the management of acute malnutrition in Nigeria and global research findings. The technical and financial contributions of UN Agencies, Development partners, Multi-lateral and Bi-lateral agencies, representatives from the Core Technical Committee on Maternal, Newborn and Child Health (MNCH), National Primary Health Care Development Agency (NPHCDA), State Ministries of Health and State Primary Health Care Development Boards is highly commendable. The Academia and Professional bodies including Dietitians Association of Nigeria, Nutrition Society of Nigeria, Paediatric Association of Nigeria, Paediatric Nurses Association of Nigeria and Consultants whose contributions in reviewing this document are also appreciated. Finally, the facilitation of the Federal Ministry of Health; Department of Family Health, Nutrition Division under the leadership of Dr. Chris Osa Isokpunwu is acknowledged gratefully. Dr. Wapada I. Balami, mni Head, Family Health Department February, 2016 vi NATIONAL GUIDELINES FOR INPATIENT MANAGEMENT OF SEVERE ACUTE MALNUTRITION IN INFANTS AND YOUNG CHILDREN IN NIGERIA FOREWORD Management of acute malnutrition has been primordial due to the nutritional effects on the socio- economic development of any nation. The 21st century eight-millennium development goals and the current seventeen Sustainable Development Goals (SDGs) emphasized at various International and National Summits have direct or indirect link to nutrition. Though poor knowledge of basic nutrition education and poverty are major challenges to optimal nutritional practices, yet, inherent behavioural factors are consistently the basic cause of poor health seeking and promotion practices in Nigeria. Nigeria has developed National Guidelines and Training Manuals for Community Management of Acute Malnutrition with emphasis on management at Primary Health facilities called Outpatient Therapeutic Programme (OTP) sites. According to WHO (2013), the use of Inpatient guidelines on Management of Severe Acute Malnutrition has contributed immensely to the reduction of case fatality load in secondary and tertiary facilities. The use of both National Guidelines for Inpatient and Community Management of Acute Malnutrition would “strengthen the effective and safe nutrition actions to counteract the public health effects of malnutrition”. The National Guidelines for Inpatient Management of Severe Acute Malnutrition at Inpatient facilities seek to provide practical guide to health and nutrition workers who design, implement, monitor and evaluate acute management programmes in Secondary and Tertiary health facilities. The adaptation of this guideline is from the 2013 WHO Updates on the management of Acute malnutrition in infants and children and the 2012 Generic Protocol for Integrated Management of Acute Malnutrition (WHO, 2013; Golden et al., 2012). It would be useful to all health practitioners and planners/managers in Public and Private Institutions as it takes cognizance of the local realities and circumstances of Nigeria. I recommend that this relevant information for management of complicated acute malnutrition will be useful to all health workers in various Referral Health institutions across the Federation. Professor Isaac F. Adewole FAS, FSPSP, DSc (Hons) Honourable Minister of Health February, 2016 vii NATIONAL GUIDELINES FOR INPATIENT MANAGEMENT OF SEVERE ACUTE MALNUTRITION IN INFANTS AND YOUNG CHILDREN IN NIGERIA LIST OF CONTRIBUTORS Federal Ministry of Health Dr. Wapada I. Balami, mni Dr. Chris Osa Isokpunwu Mrs. R. E. Gabriel Mr. J. E. Uruakpa Thompson K.C. Mr. E. A. Peter Ms. F. R. Kia Mrs. B.N. Ali Mrs. F.U.Oyibo Pharm Gbenga. S. Joseph Mrs. O.E. Oladapo National Primary Health Care Development Agency Mrs. Chinwe Ezeife Dr. Ogechi Akalonu Lagos State Ministry of Health Dr. Abimbola Ajayi Mrs. Oluwatoyin Adams Aishatu Yahya Muhammad, Kano State Primary Health Care Management Board Mrs. Endaline Ezeri, Women and Children Welfare Clinic, Sokoto Prof. E. O. Ojefeitimi, Academia Professional Bodies Sani S. Hassan, Nutrition Society of Nigeria Tamra Runsewe-Abiodun, Paediatric Association of Nigeria Lawal R. Olubunmi, Paediatric Nurses Association of Nigeria Partners Dr. Andrew L. Mbewe, WHO Dr. B.D. Omotola, UNICEF Christine Kaligirwa Oluniyi Oyedokun Dr. Tamanna Ferdous, ACF Dr. Adaeze Oramalu, SCI Dr. Friday Ilop Joseph Consultants Dr. Chika Ndiokwelu Dr. Halima Abdu Administrative staff Mrs. Theresa Danjuma Mr. Umar Abdul Mrs. Glory Owunna Mrs. Theresa Oyi viii NATIONAL GUIDELINES FOR INPATIENT MANAGEMENT OF SEVERE ACUTE MALNUTRITION IN INFANTS AND YOUNG CHILDREN IN NIGERIA ACRONYMS AND ABBREVIATIONS ACF Action La Contre Faim (Action against Hunger) ACT Artemisinin Combination Therapy AIDS Acquired immunodeficiency syndrome ART Antiretroviral therapy BCG Bacille Calmette-Guérin CSF Cerebrospinal fluid DHS Demographic and Health Survey F-75 Therapeutic milk used in acute phase of SAM Inpatient treatment F-100 Therapeutic milk used in Transition/Recovery phases of SAM treatment GAM Global Acute Malnutrition GMP Growth Monitoring and Promotion Hb Haemoglobin HIV Human immunodeficiency virus IFE Infant Feeding in Emergency (documents on feeding infants less than 6 months IM Intramuscular (injection), intramuscularly IMAM Integrated Management of Acute Malnutrition IMCI Integrated Management of Childhood Illness IPF In-Patient Facility IU International Units IV Intravenous (injection), intravenously IYCF Infant and Young Child Feeding Kg Kilogramme LoS Length of Stay MAM Moderate Acute Malnutrition MUAC Mid Upper Arm Circumference ORS Oral rehydration salt(s) OTP Outpatient Therapeutic Programme PENTA Pentavalent vaccine that has replaced Diphtheria, pertussis, tetanus (DPT) ReSoMal Rehydration solution for malnutrition RUTF Ready-to-Use Therapeutic Food (has same nutritional composition as F100 with added iron and clinically tested in efficacy trials to ensure their therapeutic equivalence to F100 SAM Severe Acute Malnutrition SC Stabilization Centre SD Standard Deviation SFP Supplementary Feeding Programme SNO State Nutrition Officer TB Tuberculosis UNICEF United Nations Children Fund WFH Weight-for-Height (Z scores) WFP World Food Programme WHO World Health Organization W/H &W/L Weight-for-Height & Weight-for-Length Z score Standard Deviations score ix
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