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Approach to Anemia PDF

52 Pages·2017·2.41 MB·English
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Approach to Anemia: An Interactive Discussion Mark M. Udden, MD Chief, Benign Hematology Baylor College of Medicine Disclosures I didn’t do it. You didn’t see me. You have no evidence. Consultant for Novartis Co-Investigator for same Free meals from Injectafer people Bart Simpson Objectives: Develop an Approach • to evaluation of microcytic anemia anemia • to evaluation of microcytic anemia • to evaluation of iron deficiency • to anemia of chronic disorders • to anemia of renal disease After the Hx and PE: Peripheral Blood Smear Reticulocyte Count Patient 1 A 25-year-old woman presents with weakness, fatigue, and pallor. She reports that she has had heavy periods for most of her adult life and that she has three children, the youngest of which is 10 months old. Her CBC shows a Hct of 28 %, with an MCV of 72 fL, and a platelet count of 540,000. The WBC is normal. Iron Deficiency Anemia • History – Bleeding – Pica – Restless Legs – Subtle neurologic dysfunction – Dysphagia • Physical Exam – Painless stomatitis – Spoon nails – Blue Sclera? – Telangiectasia Peripheral Blood Smear in Fe Deficeincy Peripheral Blood Smear in Fe Deficeincy Forms of Pica Reported in Association with Iron Deficiency • Pagophagia Ice • Geophagia Clay, dirt • Amylophagia Starch • Geomelophagia Potatoes • Gooberphagia Peanuts Unnamed Forms of Pica • Ash • Baking Powder • Card Board • Paper • Venetian Blind Dust • Wood, Toothpicks

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Mark M. Udden, MD. Chief, Benign Hematology. Baylor College of Medicine . Abcb7 deficiency and ataxia. – ALA synthase deficiency. • Acquired.
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