Table Of Content

Medicines Optimisation Contents Appendices Contents Appendix A: Guideline Development Group Declarations of Interest ....................... 2 A.1 GDG members ........................................................................................... 2 A.2 NICE Medicines prescribing centre team and additional GDG meeting attendees ................................................................................................. 11 Appendix B: Scope ................................................................................................ 16 Appendix C: How this guideline was developed ..................................................... 21 C.1 Search strategies for the Medicines Optimisation guideline ..................... 21 C.2 Review questions and review protocols ................................................... 34 C.3 Clinical consort diagrams ......................................................................... 53 C.4 Economic consort diagrams ..................................................................... 58 C.5 Clinical excluded studies .......................................................................... 64 C.6 Economic excluded studies .................................................................... 145 Appendix D: Clinical Evidence Tables and GRADE profiles ................................. 166 D.1 Evidence Tables .................................................................................... 166 D.2 Grade profiles and forest plots ............................................................... 320 D.3 Medicines reconciliation algorithm.......................................................... 399 Appendix E: Economic Evidence Tables .............................................................. 401 Appendix F: ................................................................................................................ 423 F.1 Medication review cost analysis ............................................................. 423 F.2 Full Health Economics Report ................................................................ 428 NICE guideline 5 – Medicines optimisation appendices (March 2015) 1 Medicines Optimisation Guideline Development Group Declarations of Interest Appendix A: Guideline Development Group Declarations of Interest A.1 GDG members Weeliat Chong (Chair) GDG meeting Declaration of interest Action taken Recruitment/ First None None GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh GDG No changes to record None meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Stephen Dean GDG meeting Declaration of interest Action taken Recruitment/ First None None GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July NICE guideline 5 – Medicines optimisation appendices (March 2015) 2 Medicines Optimisation Guideline Development Group Declarations of Interest GDG meeting Declaration of interest Action taken 2014) Seventh GDG No changes to record None meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) David Erskine GDG meeting Declaration of interest Action taken Recruitment/ First None None GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh GDG No changes to record None meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Leslie Galloway (member until end May 2014) GDG Type meeting Declaration of interest Action taken Recruitment/ Presents to members of EMIG Advice given regarding Specific personal non- First GDG and will be asked about speaking about financial meeting (27 medicines optimisation. medicines optimisation. November He stated he will not 2013) answer questions directly relating to medicines optimisation while on the GDG Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None NICE guideline 5 – Medicines optimisation appendices (March 2015) 3 Medicines Optimisation Guideline Development Group Declarations of Interest GDG Type meeting Declaration of interest Action taken meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Withdrew from GDG Brian Hawkins GDG Type meeting Declaration of interest Action taken Recruitment/ Presentation at training event for None Non-specific personal First GDG MSD staff - May 2011 non-financial meeting (27 November Presentation at training event for Non-specific personal 2013) Lilly staff – June 2011 non-financial Employer, Cwm Taf LHB, has Non-specific non- received funding for project from personal financial TEVA UK ltd and GSK. Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh Asked to be a speaker at the Advised he needs to be Specific personal non- GDG hospital pharmacy Europe very careful of the financial meeting (5 conference in Birmingham on 9 content of the August 2014) September 2014 on the subject of presentation and not “Optimising medicines discuss the guideline. management”. Eigth GDG No changes to record None meeting (25 November 2014) John Holden GDG meeting Declaration of interest Action taken Recruitment/ First None None GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 NICE guideline 5 – Medicines optimisation appendices (March 2015) 4 Medicines Optimisation Guideline Development Group Declarations of Interest GDG meeting Declaration of interest Action taken January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh GDG No changes to record None meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Tessa Lewis GDG meeting Declaration of interest Action taken Recruitment/ None None First GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG Wrote an article on medication None at present. Specific personal non- meeting (4 review. financial March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) NICE guideline 5 – Medicines optimisation appendices (March 2015) 5 Medicines Optimisation Guideline Development Group Declarations of Interest Harriet Lewis GDG Type meeting Declaration of interest Action taken Recruitment/ Employee of Association of None Non-specific personal First GDG British Pharmaceutical Industry financial meeting (27 (ABPI) November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Margaret Ogden GDG Type meeting Declaration of interest Action taken Recruitment/ Sits on a voluntary patient Advised not to discuss Non-specific personal First GDG advisory group with a the guideline. non-financial meeting (27 pharmaceutical company November Attended a one-to-one meeting Non-specific personal 2013) with a small pharmaceutical non-financial company. Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG Working with Alzheimer’s Society None at present Non-specific personal meeting (2 on patient reported outcomes non-financial April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG Attending a medication safety None at present Non-specific personal NICE guideline 5 – Medicines optimisation appendices (March 2015) 6 Medicines Optimisation Guideline Development Group Declarations of Interest GDG Type meeting Declaration of interest Action taken meeting (2 focus group on 11 July for NIHR non-financial July 2014) Greater Manchester Primary Care Patient Safety Translational Research Centre Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Bunis Packham GDG Type meeting Declaration of interest Action taken Recruitment/ Previously work involved None Non-specific personal First GDG medicines adherence non-financial meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Richard Seal GDG Type meeting Declaration of interest Action taken Recruitment/ Wife is a practice support Advised to be careful Non-specific personal First GDG pharmacist employed by Arden when discussing financial meeting (27 Commissioning Support Unit and medicines optimisation November also employed as a practice and to not discuss the 2013) pharmacist by a GP practice. guideline. NICE guideline 5 – Medicines optimisation appendices (March 2015) 7 Medicines Optimisation Guideline Development Group Declarations of Interest GDG Type meeting Declaration of interest Action taken Provides advisory support for Non-specific personal pharmaceutical journal for which non-financial he receives no recompense. Spoken on medicine optimisation Specific personal non- at the Pharmacy Management financial National Seminar. Second GDG No changes to record None meeting (14 January 2014) Third GDG Notified the GDG that he is no None NA meeting (4 longer a member of Pharmacy March 2014) Management Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) David Terry GDG Type meeting Declaration of interest Action taken Recruitment/ Presenting at a conference in Advised not to discuss Non-specific personal First GDG March 2014. the guideline and be non-financial meeting (27 careful of presentation November content. 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG Co-ownership of NuCo R&D Ltd. None at present but Non-specific personal meeting (4 NuCo was incorporated as a may review at future financial March 2014) company on 26th February 2014. meetings. It is a research company but may in the future also distribute and or sell medicines. At present does not believe there is anything on NuCo’s agenda / portfolio that causes concern with this NICE guideline 5 – Medicines optimisation appendices (March 2015) 8 Medicines Optimisation Guideline Development Group Declarations of Interest GDG Type meeting Declaration of interest Action taken guideline. NuCo is not currently trading. Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG Accepted an invitation to take None Non-specific personal meeting (29 part in The Clinical Pharmacy non-financial April 2014) Congress 2014, 25 – 26 April 2014. He joined a panel, sponsored by Sanofi-Aventis to discuss the subject: The wider role of pharmacists in delivering outcomes in diabetes Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Katrina Vout GDG meeting Declaration of interest Action taken Recruitment/ First None None GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh GDG No changes to record None meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) NICE guideline 5 – Medicines optimisation appendices (March 2015) 9 Medicines Optimisation Guideline Development Group Declarations of Interest Mary Weatherstone GDG Type meeting Declaration of interest Action taken Recruitment/ Member of an NHS England Advised not to discuss Specific personal non- First GDG clinical reference group on the guideline at the financial meeting (27 Medicines Optimisation. reference group. November 2013) Is a NICE MPC Associate Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Nigel Westwood GDG Type meeting Declaration of interest Action taken Recruitment/ Received travel expenses and Advised not to discuss Non-specific personal First GDG attendance fees from a number of the guideline. financial meeting (27 pharmaceutical companies when November attending meetings (Abbott, 2013) Proctor and Gamble, Kinetic Concepts Inc., UCB and Warner Chillcott) as a speaker on patient experience to pharmaceutical staff, trainee medical professionals and specialist registrars. Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 NICE guideline 5 – Medicines optimisation appendices (March 2015) 10

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NICE guideline 5 – Medicines optimisation appendices (March 2015). 1. Medicines Optimisation. Contents . Sixth GDG meeting (2 July. 2014).
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428 Pages·2015·8.41 MB·English
by  Michael Heath
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Medicines Optimisation Contents Appendices Contents Appendix A: Guideline Development Group Declarations of Interest ....................... 2 A.1 GDG members ........................................................................................... 2 A.2 NICE Medicines prescribing centre team and additional GDG meeting attendees ................................................................................................. 11 Appendix B: Scope ................................................................................................ 16 Appendix C: How this guideline was developed ..................................................... 21 C.1 Search strategies for the Medicines Optimisation guideline ..................... 21 C.2 Review questions and review protocols ................................................... 34 C.3 Clinical consort diagrams ......................................................................... 53 C.4 Economic consort diagrams ..................................................................... 58 C.5 Clinical excluded studies .......................................................................... 64 C.6 Economic excluded studies .................................................................... 145 Appendix D: Clinical Evidence Tables and GRADE profiles ................................. 166 D.1 Evidence Tables .................................................................................... 166 D.2 Grade profiles and forest plots ............................................................... 320 D.3 Medicines reconciliation algorithm.......................................................... 399 Appendix E: Economic Evidence Tables .............................................................. 401 Appendix F: ................................................................................................................ 423 F.1 Medication review cost analysis ............................................................. 423 F.2 Full Health Economics Report ................................................................ 428 NICE guideline 5 – Medicines optimisation appendices (March 2015) 1 Medicines Optimisation Guideline Development Group Declarations of Interest Appendix A: Guideline Development Group Declarations of Interest A.1 GDG members Weeliat Chong (Chair) GDG meeting Declaration of interest Action taken Recruitment/ First None None GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh GDG No changes to record None meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Stephen Dean GDG meeting Declaration of interest Action taken Recruitment/ First None None GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July NICE guideline 5 – Medicines optimisation appendices (March 2015) 2 Medicines Optimisation Guideline Development Group Declarations of Interest GDG meeting Declaration of interest Action taken 2014) Seventh GDG No changes to record None meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) David Erskine GDG meeting Declaration of interest Action taken Recruitment/ First None None GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh GDG No changes to record None meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Leslie Galloway (member until end May 2014) GDG Type meeting Declaration of interest Action taken Recruitment/ Presents to members of EMIG Advice given regarding Specific personal non- First GDG and will be asked about speaking about financial meeting (27 medicines optimisation. medicines optimisation. November He stated he will not 2013) answer questions directly relating to medicines optimisation while on the GDG Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None NICE guideline 5 – Medicines optimisation appendices (March 2015) 3 Medicines Optimisation Guideline Development Group Declarations of Interest GDG Type meeting Declaration of interest Action taken meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Withdrew from GDG Brian Hawkins GDG Type meeting Declaration of interest Action taken Recruitment/ Presentation at training event for None Non-specific personal First GDG MSD staff - May 2011 non-financial meeting (27 November Presentation at training event for Non-specific personal 2013) Lilly staff – June 2011 non-financial Employer, Cwm Taf LHB, has Non-specific non- received funding for project from personal financial TEVA UK ltd and GSK. Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh Asked to be a speaker at the Advised he needs to be Specific personal non- GDG hospital pharmacy Europe very careful of the financial meeting (5 conference in Birmingham on 9 content of the August 2014) September 2014 on the subject of presentation and not “Optimising medicines discuss the guideline. management”. Eigth GDG No changes to record None meeting (25 November 2014) John Holden GDG meeting Declaration of interest Action taken Recruitment/ First None None GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 NICE guideline 5 – Medicines optimisation appendices (March 2015) 4 Medicines Optimisation Guideline Development Group Declarations of Interest GDG meeting Declaration of interest Action taken January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh GDG No changes to record None meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Tessa Lewis GDG meeting Declaration of interest Action taken Recruitment/ None None First GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG Wrote an article on medication None at present. Specific personal non- meeting (4 review. financial March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) NICE guideline 5 – Medicines optimisation appendices (March 2015) 5 Medicines Optimisation Guideline Development Group Declarations of Interest Harriet Lewis GDG Type meeting Declaration of interest Action taken Recruitment/ Employee of Association of None Non-specific personal First GDG British Pharmaceutical Industry financial meeting (27 (ABPI) November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Margaret Ogden GDG Type meeting Declaration of interest Action taken Recruitment/ Sits on a voluntary patient Advised not to discuss Non-specific personal First GDG advisory group with a the guideline. non-financial meeting (27 pharmaceutical company November Attended a one-to-one meeting Non-specific personal 2013) with a small pharmaceutical non-financial company. Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG Working with Alzheimer’s Society None at present Non-specific personal meeting (2 on patient reported outcomes non-financial April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG Attending a medication safety None at present Non-specific personal NICE guideline 5 – Medicines optimisation appendices (March 2015) 6 Medicines Optimisation Guideline Development Group Declarations of Interest GDG Type meeting Declaration of interest Action taken meeting (2 focus group on 11 July for NIHR non-financial July 2014) Greater Manchester Primary Care Patient Safety Translational Research Centre Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Bunis Packham GDG Type meeting Declaration of interest Action taken Recruitment/ Previously work involved None Non-specific personal First GDG medicines adherence non-financial meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Richard Seal GDG Type meeting Declaration of interest Action taken Recruitment/ Wife is a practice support Advised to be careful Non-specific personal First GDG pharmacist employed by Arden when discussing financial meeting (27 Commissioning Support Unit and medicines optimisation November also employed as a practice and to not discuss the 2013) pharmacist by a GP practice. guideline. NICE guideline 5 – Medicines optimisation appendices (March 2015) 7 Medicines Optimisation Guideline Development Group Declarations of Interest GDG Type meeting Declaration of interest Action taken Provides advisory support for Non-specific personal pharmaceutical journal for which non-financial he receives no recompense. Spoken on medicine optimisation Specific personal non- at the Pharmacy Management financial National Seminar. Second GDG No changes to record None meeting (14 January 2014) Third GDG Notified the GDG that he is no None NA meeting (4 longer a member of Pharmacy March 2014) Management Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) David Terry GDG Type meeting Declaration of interest Action taken Recruitment/ Presenting at a conference in Advised not to discuss Non-specific personal First GDG March 2014. the guideline and be non-financial meeting (27 careful of presentation November content. 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG Co-ownership of NuCo R&D Ltd. None at present but Non-specific personal meeting (4 NuCo was incorporated as a may review at future financial March 2014) company on 26th February 2014. meetings. It is a research company but may in the future also distribute and or sell medicines. At present does not believe there is anything on NuCo’s agenda / portfolio that causes concern with this NICE guideline 5 – Medicines optimisation appendices (March 2015) 8 Medicines Optimisation Guideline Development Group Declarations of Interest GDG Type meeting Declaration of interest Action taken guideline. NuCo is not currently trading. Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG Accepted an invitation to take None Non-specific personal meeting (29 part in The Clinical Pharmacy non-financial April 2014) Congress 2014, 25 – 26 April 2014. He joined a panel, sponsored by Sanofi-Aventis to discuss the subject: The wider role of pharmacists in delivering outcomes in diabetes Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Katrina Vout GDG meeting Declaration of interest Action taken Recruitment/ First None None GDG meeting (27 November 2013) Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh GDG No changes to record None meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) NICE guideline 5 – Medicines optimisation appendices (March 2015) 9 Medicines Optimisation Guideline Development Group Declarations of Interest Mary Weatherstone GDG Type meeting Declaration of interest Action taken Recruitment/ Member of an NHS England Advised not to discuss Specific personal non- First GDG clinical reference group on the guideline at the financial meeting (27 Medicines Optimisation. reference group. November 2013) Is a NICE MPC Associate Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 April 2014) Fifth GDG No changes to record None meeting (29 April 2014) Sixth GDG No changes to record None meeting (2 July 2014) Seventh No changes to record None GDG meeting (5 August 2014) Eigth GDG No changes to record None meeting (25 November 2014) Nigel Westwood GDG Type meeting Declaration of interest Action taken Recruitment/ Received travel expenses and Advised not to discuss Non-specific personal First GDG attendance fees from a number of the guideline. financial meeting (27 pharmaceutical companies when November attending meetings (Abbott, 2013) Proctor and Gamble, Kinetic Concepts Inc., UCB and Warner Chillcott) as a speaker on patient experience to pharmaceutical staff, trainee medical professionals and specialist registrars. Second GDG No changes to record None meeting (14 January 2014) Third GDG No changes to record None meeting (4 March 2014) Fourth GDG No changes to record None meeting (2 NICE guideline 5 – Medicines optimisation appendices (March 2015) 10

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NICE guideline 5 – Medicines optimisation appendices (March 2015). 1. Medicines Optimisation. Contents . Sixth GDG meeting (2 July. 2014).
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