Table Of Content

SUBJECT INDEX A transgenic mice studies of, 496 Behavioral genetics, 1-19 £-Amyloid protein, 481 1Q and, 2, 4-6 AB Anisomycin, 130 personality traits and, 2, 6-8 amyloid precursor protein and, Ankyrin, 114 general occupational themes, 479-80, 482-89 Anti-Hu sensory neuronopathy, 7 presenilin and, 495 212-14 phenotypic variance, 2 Acetylcholine signaling, 299-300 Anti-MAG, 211-12 Behavioral plasticity, 407-8, 434 Action potential Aplysia, 33-34, 38-39, 127, Bipolar disorder linkage studies, presynaptic, 158, 161 131-44 10 Activating transcription factor cAMP-PKA pathway and Blood-nerve barrier, 189, 191-92 group of CREB family, 128, long-term sensitization in, leukocyte trafficking, 192 130 131-32 Bone morphogenetic proteins, 464 Adhesion molecules, 97-120, 192 californica, 33-34, 38-39 LI, 97, 112-20 CREB activation, 140-41 merosin, 97-105, 120 CREB and memory formation C muscular dystrophy and, in, 127, 131-32 97-105 long-term potentiation, 139 Ca?+-binding proteins, 75, 81-92 mutations in, 97-120 Apolipoprotein (apoE), 479, 482 C2-domains and, 89 Po, 97, 105-7, 109-12, 120 Apoptosis C>-domains, 75, 86-90 vascular cell adhesion merosin and, 102 Ca?+-binding properties of, 89 molecule-1 (VCAM1), 192 zinc and, 356-62 Caenorhabditis elegans, 279-304, Adoption studies, 2-8, 12, 48 Attention-deficit disorder linkage 380 Agrin, 103 studies, 11 chemosensory neurons, 287-92 Alcohol dehydrogenase, 10 Audition, 167, 227, 235-37, TGF-B-related peptide and, Alcoholism 252-53, 260-61 279, 289-91 adoption studies, 13 neuronal pooling and, 252-53 dauer larvae of, 289-92 linkage studies, 11 Autapse, 39 G-protein signaling pathways Aldeyhyde dehydrogenase Autism linkage studies, 11 in, 279-304 (ALDH), 10 Autoimmunity, 187, 190-217 heat-shock gene pair, 380 Alzheimer’s disease, 479-98, 364 mechanisms of, 193-95 mechanosensation in, 279, amyloid precursor protein antibody disruption of 281-304 (APP) and, 479-80, neuronal function, 195 body touch response, 284 482-89 antibody-mediated attack, nose touch response, 284 autosomal dominant familial 195-96 thermosensation, 284-85 (FAD), 479-80, 482-98 cytokines’ and macrophages’ touch reception model, cellular abnormalities, 482 direct effects, 195 282-83 clinical features, 480, 482 cytotoxic T cell-mediated nervous system structure of, neuropathology, 480 attack, 193-94 279-81 presenilins and, 479-80, neuropathies, 196-217 neurotransmitter receptors in, 483-84, 489-95 therapies, 215-17 292-97 tau and glycosaminoglycan superantigens and, 190 excitatory glutamate interactions and, 481 Axolotl receptors, 294-95 zinc toxicity and, 364 neural plate fate maps, 449-59 GABA, 296 AMPA receptor—mediated Axonal guidance, 309-38 inhibitory glutamate responses ephrins and, 309-38 receptors, 295 zinc and, 351, 358, 362, 365 Eph receptors and, 309-38 nicotinic acetylcholine Amyloid precursor protein (APP), motor, 328-32 receptors, 292-94 479-80 regional patterning of nervous Calmodulin kinases (CaMKs), Alzheimer’s disease and system, 332-38 128 alterations of, 479-80, retinotectal topographic cAMP responsive element (CRE), 482-89 mapping, 319-28 127-45 gene-targeted mice studies of, cAMP responsive element binding 496-98 B protein (CREB), 127-45 Kunitz family of protease activating transcription factor inhibitors (KPI), 485 Bartel cortex, 165-66 (ATF) group, 128 507 508 SUBJECT INDEX CREB group, 128 laminar organization of, Dystrophin-glycoprotein complex, CREM group, 128 52-68 100-3 memory formation and, Cortical map plasticity, 149, 152, dystrophin-associated 127-45 167-80 glycoproteins (DAGs), Aplysia, 131-32 CaM-kinase-dependent, 174-75 100-1 Drosophila, 132-33, 137 horizontal connectivity and, dystrophin-associated proteins mutant mice, 133-35, 152 (DAPs), 100 137-38 models of, 175-77 Docking, 75, 77, 84 rats, 135 NMDA-dependent, 174-75 a-latrotoxin and, 84 synaptic remodeling, 143-44 sites of, 173-74 Dopamine receptor transcriptional activation, synaptic plasticity alcoholism and, 10 128-29, 143 relationship to, 170-80 schizophrenia and, 9 transcriptional repression, training dependent, 167-70 Dynamic clamp, 25-29 129-30, 139 Cortical representational Dyslexia linkage studies, 11 cAMP response element plasticity, 149, 153, 162-67 modulator (CREM) gene, auditory, 167 128, 130 barrel cortex and, 165-66 E isoform somatosensory cortex and, inducible cAMP early 162-65 Ecdysone repressor (ICER), 128, 130 visual cortex and, 166-67 inducible gene expression and, cAMP signal transduction cascade Cortical synaptic plasticity, 149, 377, 379-89, 401-2 olfactory learning and, 411, 153-60, 170-80 Electrical coupling, 29-30 416 relationship to cortical map Endocytosis, 77 Campylobacter, 190, 196, 207-8 plasticity, 170-80 Eph receptors, 309-38 Cellular conditioning, 153, CREB (See also under cAMP bidirectional signaling and, 160-62 responsive binding element) 319 auditory cortex, 161 CREB-binding protein, 139 ligand (See Ephrins) intracortical microstimulation CREB-mediated gene expression, phylogeny, 314 (ICMS), 162 429-30 receptor-ligand binding, 315-17 Cerberus, 466 CREB-mediated transcription, regional patterning of nervous Charcot-Marie-Tooth disease, 97, 424-25 system and, 332-38 107-12 Cyclic adenosine monophosphate, Ephrins, 309-38 mutations of Po gene and, 285 axon guidance and, 311, 319-28 107-12 (See also under cAMP) retinotectal topgraphic Chemoaffinity labels, 320-21 Cyclic guanosine monophosphate mapping, 319-28 Chemosensory neurons (cGMP), 285 bidirectional signaling and, 319 C. elegans and, 279, 286-92 Cytomegalovirus, 206 expression in forebrain, 334-35 G protein-coupled receptors phosphorylation sites, 318 and, 286-87 phylogeny, 314 signal transduction, 287-88 D receptor-ligand binding, 315-17 sr genes and, 286-87 structure, 313 Chordin, 466 Dejerine-Sottas diseases, 107-12 Epilepsy Chronic inflammatory mutations of Po gene and, zinc exposure and, 347, 364 demyelinating 107-12 Epistasis, 417 polyneuropathy (CIDP), Diacylglycerol-protein kinase C Estrogen receptor, 377, 379, 208-9 (DAG-PKC), 131 387-89 Computation, 25-41 Drosophila melanogaster mutant, 387-89 Cortex, 36, 149-80 cAMP-PKA pathway and N-Ethylamaleimide sensitive architecture, 151-52 learning in, 132 factor (NSF), 78 circuitry, 150-52 learning and memory in, Eukaryotic cells, 77 cortical plasticity, 149-80 132-33, 135, 137, 144, Excitatory junctional potentials cortical map plasticity, 149, 407-38 (EJPs), 34 152, 167-80 genetic dissection, 407-8, Excitatory postsynaptic potential synaptic, 149, 153-60, 420-38 (EPSP), 32, 153-59 170-80 quantitative genetic studies, LTD of, 157-59 cortical representational 408-10, 416-20 LTP of, 154-57 plasticity, 149, 153, single-gene mutants, 410-16 Excitotoxicity 162-67 olfactory memory in zinc modulation of, 364—67 information flow, 151-52 CREB and, 127, 132-33, Exocytosis synaptic depression in, 36 135, 137, 144 synaptic vesicle (See Synaptic Cortical circuits Duchenne muscular dystrophy, 99 vesicle exocytosis) SUBJECT INDEX 509 Experimental autoimmune neuritis Gap junctions acute motor-sensory axonal (EAN), 193, 202 Pas-related proteins and, neuropathy (AMSAN), Extrastriate cortex, 58 296-97 198-99, 202 GDI, 81-82, 86 Campylobacter and, 190, 196, GDP, 81-82, 86 207-8 F Gene expression, inducible, Fisher syndrome, 199, 206 377-402 susceptibility factor, 206 Facilitation, 25, 35-37 FK5S06 dimer, 379, 383-85 Glycosylphosphatidylinositol Fate maps, 445, 449-59 glucocorticoid, 385-89 (GPI), 78 vertebrate prosencephalic heat shock and, 378-80 neural plate, 449-59 heavy metal ion, 379-81 telencephalic subdivisions, interferon, 381-83 H 458-59 lac operator/repressor-based FGF8, 445, 460, 467-68 systems, 389-92 Heat-shock FK506 dimer, 383-85 tetracycline transactivator, 377, response, 378-80 Follistatin, 466 379, 392-98 transcription factors, 378 Forebrain, 332-38, 445-72 Gene identification Heavy metal ion, 379-81 Eph receptors and, 332-38 association studies, 4, 11 Hebbian ephrins and, 332-38 behavioral traits and, 2-4 learning rule, 152, 160 neural plate linkage studies, 4, 9-12 plasticity, 153-57, 165 eye field induction and schizophrenia, 9-10 Hebb’s postulate, 154 patterning, 469-70 Gene targeting, 127 Hemagglutinin, 77-79, 90 fate maps of, 449-59 General occupational themes, 7 Heritability, 1-19 gene expression maps in, Genetic background, 407 general cognitive ability, 6 459-61 Genetic dissection joint influence of genes and olfactory bulb induction, of learning and memory, 407-8, environment, 2 470 420-38 personality and interests, 6-8 posterior pituitary, 470-71 biochemical pathways, psychopathology, 8-12 telencephalon induction and 420-24 sexual orientation, 7, 9 patterning, 468 memory formation, 425-34 specific mental abilities, 6 ventral hypothalamus, neuroanatomical pathways, social attitudes, 8 470-71 421-24 twin studies, 2-8, 12, 18 Founder effect, 419 synaptic plasticity, 424-25 Herpes simplex virus, 392-93 Fukuyama’s classical congenital Genotype-environment Hippocamposepal projection, 328 muscular dystrophy (FCMD), correlation, 14, 16-19 Hippocampus 99 Genotype-environment CREB activation in, 141-43 Fusion, 75-92 interaction, 1, 14, 17-19 homosynaptic LTD in, 157 Ca**+ -triggered, 82-92 Glial cell death late-LTP induction in, 139 lipid bilayer, 77 zinc-induced, 354-62 LTP and, 150, 154, 157 proteins involved in, 78-80 Glucocorticoid zinc release and re-uptake in, rab3 and, 82-88 inducible gene expression and, 350 synaptotagmin and, 75-79, 81, 385-89 Hox genes, 332 88-92 Glucocorticoid-responsive Hypothalamus, 470-71 elements (GREs), 385 G Glutamate receptors excitatory, 294-95 I G protein-coupled receptors inhibitory, 295 chemosensation in C. elegans Glycogen synthase kinase, Immunoglobulin superfamily, and, 286-92 192 signal transduction in GTP, 81-82, 88 Inducible cAMP early repressor chemo-sensory neurons, GTP-binding activity (ICER), 128, 130 287-92 rab3 and, 81 Inhibitory postsynaptic potentials yr gene expression and, GTP-binding proteins, 75-92 (IPSPs), 157-60 286-87 Guillain-Barré syndrome, 187, Integrin, 102-3, 105, 192 G-protein signaling pathway 190-91, 196-208 Intercellular adhesion molecule-1 C. elegans, 297-304 acute inflammatory (ICAM-1), 192 G proteins, 279, 297-304 demyelinating Interferon, 377, 379, 381-83 Gal4 polyneuropathy (AIDP), Interferon-y , 193 Saccharomyces cerevisiae, 198, 202 Interleukin-6, 381 378 acute motor axonal neuropathy Intraocular dominance, 417 Gal4-ER, 386 (AMAN), 199, 202-3 Intrinsic circuits, 47, 68-70 510 SUBJECT INDEX Ischemia receptors in C. elegans dystrophin-glycoprotein transient global and, 292-94 complex and, 100-3 zinc exposure and, 347, Long-term depression (LTD), a@2 gene mutations, 104-5 362-63 149-80 muscular dystrophy and, Ivermectin, 295 associative, 158-59 97-105 of excitatory synapses, 157-59 myelinogenesis and, 104 K heterosynaptic, 157, 159, 178 myogenesis and, 102 homosynaptic, 157, 159 peripheral nerves and, 102-3 Long-term facilitation (LTF), 131 structure, 98-99 Krox-20 gene, 333-34 Kunitz family of protease Long-term potentiation (LTP), Metal-activated factors (MAFs), 127, 136-40, 149-80, 380-81 inhibitors, 485 399-402 Metallothionein associative, 1174-75, 177-78 gene family, 380-81 L early (E-LTP), 136 proteins of excitatory synapses, 154-57 cellular zinc homeostasis LI cell adhesion molecule, 112-20 hippocampal, 150, 154 and, 360 CRASH syndrome and, | 14-20 late (L-LTP), 136, 139 Microneurography, 254-56, Lactose operon, 378 neocortical, 154-57 268-69 Lamert-Eaton myasthenic induction protocols, 156 MK-801, 85 syndrome (LEMs), 190, 195, zinc and, 353-54 Modulatory commissural neuron | 214-15 Long-term sensitization (LTS), (MCN1), 32 Lamin, 98, 100-3, 114 131-32 Molecular mimicry, 190, 198, Lateral geniculate nucleus (LGN), cAMP-PKA pathways in 206-8 47-48, 50, 70 Aplysia and, 131-32 Monoamine oxidase A gene, | 1 neuronal projections to Lower envelope principle, 241-43, Monoclonal gammopathy, 209-10 extrastriate cortex, 58-68 265-68 Monocyte chemoattractant a-Latrotoxin, 82, 84 Lymphocytes, 188-89 protein-1, 189 Learning and memory, 127-45, Multifocal motor neuropathy, 407-38 210-11 genetic architecture underlying, M Muncl8, 78-80 410, 416-20 Muscle-eye-brain disease, 99 genetic dissection of, 407-8, Macrophages, 188 Muscular dystrophy, 97-105 420-38 Manic depression linkage studies, congenital, 99-105 memory consolidation features 10 classification, 99-100 universally conserved, 437 MASA syndrome, | 14-15 dystrophin-glycoprotein memory formation, 425-34 Mast cells, 188-90 complex and, 100-3 temporal phases of, 425 Mechanosensation, 279, 281 mutations in merosin and, Pavlovian olfactory learning, Membrane fusion, 75-92 98-105 410, 416, 420, 423 Ca?+-triggered, 82 Mutant mice quantitative genetic studies, hemagglutinin and, 77-78 CREB and long-term memory, 408-10, 416-20 a-latrotoxin and, 82 127, 133-35, 137-38 single-gene mutants, 410-16 mechanisms, 77-78 Mycoplasma arthritidis, 190 synaptic plasticity, 424-25 rab3 and, 75-79, 81-88 Mycoplasma pneumoniae, 207 (See also Memory) regulation, 81 Myelin-associated glycoprotein, Leukocyte-endothelial synaptic vesicle exocytosis and, 191 interactions, 192 76-77 Myelination cell adhesion molecules and, synaptotagmin and, 75-79, 81, merosin and, 97-104 192 88-92 Po and, 97, 105-7, 109-12 Limulus, 233, 235 zipper model, 80-81 Myelinogenesis Linkage studies Memory merosin and, 104 alcoholism, 10-11 CREB and, 127-45 Myogenesis attention-deficit disorder, 11 long-term facilitation and, 131 merosin and, 102 borderline mental retardation, long-term potentiation and, 127, 11 136-40 dyslexia, 11 (See also Learning and N impulsive agression, | | memory) manic depression, 10 Mental retardation Nature-nurture debate, | schizophrenia, 9-10 LI cell adhesion molecule Nerve growth factor (NGF), 312 Tourette syndrome, 11] mutations and, 114-16 N-ethylamaleimide sensitive Locomotion Merosin, 97-105, 120 factor (NSF), 78 nicotinic acetylcholine apoptosis and, 102 Neural crest, 332-38 SUBJECT INDEX 511 Neural plate, 445-72 G protein—couple receptors gene-targeted mice, 496 A/P patterning, 463-65 and, 286-87 transgenic mice, 497-98 fate maps of, 449-59 Olfactory learning Primary visual cortex, 47-70 gene expression maps in, cAMP signal transduction feedback pathway, 47, 53-68 459-81 cascade and, 411, 416 feedforward pathway, 47, 53-68 mediolateral patterning, 463-65 CREB and, 127, 132-33, 135, striate cortex, 47 prosencephalic regionalization 137, 144 V1, 47-70 of, 471-72 Paviovian, 410, 416, 420, 423 functional organization, later, 471-72 48-50 Neural tube, 332-38 geniculate input to, 50-52, P Neurodegeneration 58-68 zinc and, 354-68 interlaminar connections, Neuromere, 445 Parallel pathways, 47, 53-68 52-68 Neuromodulation, 37-39 Pas-related gene family, macaque, 47~70 Neuromuscular junction, 424 296-97 (See also Vision) Neuronal cell death, 354-68 Pas-related proteins, 297 Priming, 75, 77-80 zinc-induced, 354-68 Pattern formation, 445 proteins involved in, 78-80 cellular zinc homeostasis Pavlovian conditioning, 407, 410, Proboscis extension reflex (PER), and, 360-69 416, 420, 423 408, 422 excitotoxicity, 364-67 PDZ-domains, 75, 87 Proctolin, 38-39 inhibition of energy Perception Progesterone antagonist (RU486), production and, 362 neuronal activity and, 227-72 386-87 metallothionein proteins and, Perceptual tasks Prosencephalon, 445 360-61 defined, 228 Prosomeres, 446 toxic zinc entry into neurons, Peripheral nervous system, Prosomeric model, 458 358-59 187-217 Protein kinase A (PKA), 128, 131, Neuronal detection and blood-nerve barrier, 191-92 136, 141-43 discrimination function immune cell types of, 188-89 inhibitor (PKI), 141-43 measurement of, 231-33 immune injury and, 187-217 regulatory subunit of, 136 Neuronal pooling, 227, 241, Phenotypic variance, 2 Protein kinase C (PKC), 128 243-44, 249-52, 265-68 Pituitary adenylyl cyclase Protein-protein interactions, 76 detection of temperature activating peptide (PACAP), Proton pump, 77 changes and, 250-51 425 Psychometric detection function, vision and, 241, 243-44, 252 Plasma cell dyscrasia, 191 231, 233, 238 Neuropathies, autoimmune, 187, Plasticity, 149-80, 407-8, 434 Psychopathology, 8-12 196 associative (Hebbian), 153-58, Puromycin, 130 Neurotoxicity, 347 165, 170 Pyloric network, 30-32 Neurotransmitter receptors neocortex, 154 Pyramidal neurons, 64-68 C. elegans, 279, 292-27 behavioral, 107-8, 434 Neurotransmitter release, 75-92 cellular conditioning studies Nicotinic acetylcholine receptors and, 153, 150-62 R C. elegans and, 292-94 cortical map, 149, 164, 168-80 N-methyl-D-aspartate (NMDA) cortical representational, 149, Rab3, 75-79, 81-88 receptors, 129, 140, 154, 153, 162-67 dissociation 157-58, 351, 354, 365, cortical synaptic, 149-60, Ca?+ -triggered fusion and, 398-402 170-87 82-84 LTP and Hebbian, 153-58, 165, 170 effectors, 82, 85-88 tetracycline transactivator inhibitory, 159-60 GDI and, 81-82 system of inducible gene Po GDP and, 81-82 expression and, 398-402 Charcot-Marie-Tooth disease GTP-binding activity and, 81 zinc and, 351, 354, 365 and, 107-12 regulation, 85 Noggin, 466 Dejerine-Sottas diseases and, subfamily, 81 Nonshared environment, 1, 2, 5, 107-12 synaptic vesicle membrane 12-19 myelination and, 105-12 fusion and, 75-79, 81-88 Prechordal plate, 445, 464 Rabphilin, 85-88 Preoptic area, 458 Receptor tyrosine kinases O Presenilins (PS1, PS2) Eph receptors, 309-38 and AB, 495 transmembrane ligands for, Okadaic acid, 142 Alzheimer’s disease and 317-19 Olfaction, 279, 286-88, 411, 416 mutations in, 479-80, Regulation C. elegans 483-84, 489-95 activity-dependent, 25-41 512 SUBJECT INDEX Retinal ganglion cells (RGCs), Mycoplasma Thermotaxis 51 arthritidis-derived, 190 C. elegans and, 284-85, 287 Retinotectal topographic mapping, Staphylococcal enterotoxin B, Topographic maps 319-28 190 hippocamposeptal, 328 ephrins and Synapsins, 77 retinotectal, 319-28 chemoaffinity labels, 321-22 Synaptic depression, 25, 35-41 Tourette syndrome (TS) linkage mechanism, 324-26 cortex, 36 studies, 1 Rhombencephalon, 446 Synaptic plasticity, 424-25, Transcription, 127-45 RIM, 85-88 398-401 CREB-dependent Rsk-2, 114, 120 genetic dissection in D. activation, 128-29 RU486, 386-87 melanogaster of, 424-25 repression, 129-30 CREB-mediated Transgenic mice, 377-402 transcription and, 424 Trinucleotide repeat disorders S neuromuscular junction and, bipolar disorder, 10 424 linkage studies, 11 SCAMPs, 77 Synaptic remodeling, 143-44 Twin studies, 2-8, 12, 18 Schizophrenia CREB and, 143 human sexual orientation, 7 adoption studies, 13 Synaptic vesicle exocytosis, Minnesota Multiphasic linkage studies, 9-10 75-92 Personality Inventory serotonin receptor system docking, 75, 77, 84 (MMPI), 7 polymorphism and, 10 membrane fusion, 75-92 Minnesota Study of Twins nonshared environmental priming, 75, 77-80 Reared Apart (MISTRA), factors and, 15 rab3 and, 82-85, 88 6,7 Selectin, 192 SNAP-25 and, 78-79 Minnesota Twin Study of Adult Sensory threshold, 230 synaptobrevin and, 78, 78-80 Development and Aging Ser 142, 129-30 synaptotagmin and, 75-79, 81, (MTSADA), 5 Serotonin (5-HT), 131, 296 88-92 psychpathology, 8 Serotonin receptor system syntaxin and, 78-80 social attitudes, 8 polymorphism Synaptobrevin, 77, 78-80 Swedish Adoption/Twin Study schizophrenia and, 10 Synaptogyrin, 77 of Aging (SATSA), 5-6 Seven transmembrane receptors Synaptophysin, 77 Tyrosine kinase, 309-38 (7-TMRs), 297 Synaptoporin, 77 Sexual orientation Synchrony, 32 linkage studies, 11 Syndactyly, 165, 169 V twin studies, 11 Synaptotagmin Xq28 and, 11 effectors, 90-91 vi Short-term facilitation (STF), membrane fusion and, 75-79, functional organization, 131 81, 88-92 48-50 Slow inhibition, 32 Syntaxin, 78-80 blobs and interblobs, 50 Small-cell lung cancer (SCLC), orientation and ocular 190 dominance columns, SNARE, 80 T 49-50 Soluble NSF attachment proteins geniculate input to, 50-52, (SNAPs), 78-80 T cell antigen receptor, 383 58-68 receptor (SNARE), 80 T cell receptors, 190 koniocellular, 5~52, 58-68 a-SNAP, 80 T cells magnocellular, 50-52, SNAP-25, 78-80 cytotoxic T cell-mediated 58-68 Somatosensory cortex, 162-65 attack, 193-94 parvocellular, 50-52, 58-68 cortical plasticity and, helper/inducer, 194 interlaminar connections, 162-65 Temperature detection, 250-51, 52-68 Somatosensory system, 227, 263-64, 285 macaque, 47-70 235-72 Tetracycline-inducible gene Vascular cell adhesion molecule-1 frequency discrimination, expression, 377, 379, (VCAM1), 192 247 392-402 Vesicle-associated membrane Staphylococcal enterotoxin B, Tetracycline transactivator, 377, proteins (VAMPs), 77-78 190 379, 392-402 Vision, 227, 235-45 Striate cortex, 47 TGF-f-related peptide, 279 cortical detection of spatial Strong Vocational Interest Thermosensation, 250-51, contrast patterns, 245-46 Inventory/Strong-Campbell 263-64, 285 motion perception, 256-60 Interest Inventory, 7 cGMP second messenger in neuronal pooling and, 241, Superantigens, 190-91 C. elegans and, 285 243-44 SUBJECT INDEX 513 visual pattern discrimination, neural plate fate map of, global ischemia and, 347, 246-47 449-59 362-63 (See also Primary visual cortex) glycine receptor—mediated response, 353 Z membrance receptor and Ww channel effects, 350-53 Zebrafish, 408, 449-59, 467 LTP and, 353-54 Walker-Warburg syndrome, neural plate fate map of, metalloenzymes, 348 99 449-59, 467 neuronal cell death induced by, Zinc, 347-68 354-64 xX Alzheimer’s disease and, NMDA receptor—mediated 364 response and, 351, 358, X-linked hyrocephalus, 97, AMPA receptor—mediated 362 114 responses and, 351, 358, synaptic release and. LI cell adhesion molecule and, 362 transient global ischemia and, 114-15 epilepsy and, 347, 364 347 Xenopus GABA and, 352-53 zinc-binding proteins, 348-49