Annals of internal Medicine Volume 125 Number 1 1 July 1996 ARTICLES AdLibitum 7 The Long-Term Clinical Course of Acute Deep Venous Prandoni, Lensing, Letters 77 Thrombosis Cogo, and others Three-Year Follow-up on Effects The Appropriateness of Coronary Artery Bypass Graft Leape, Hilborne, of Transdermal Estrogen Surgery in Academic Medical Centers Schwartz, and others Medical Heuristics Deletion Polymorphism of the Angiotensin I- Winkelmann, Nauck, The Literature Converting Enzyme Gene Is Associated with Klein, Russ, B6hm, of Medicine Increased Plasma Angiotensin-Converting Enzyme Activity Siekmeier, Ihnken, 79 but Not with Increased Risk for Myocardial Infarction Verho, GroB, and Marz and Coronary Artery Disease Somatostatin Receptor Scintigraphy: Its Sensitivity Gibril, Reynolds, Compared with That of Other Imaging Methods in Doppman, Chen, Detecting Primary and Metastatic Gastrinomas. Venzon, Termanini, A Prospective Study Weber, and others BRIEF COMMUNICATION Nonsustained Ventricular Tachycardia in Coronary Artery Buxton, Lee, DiCarlo, Disease: Relation to Inducible Sustained Ventricular Echt, Fisher, Greer, Tachycardia Josephson, and others UPDATE Update in Cardiology Alpert and Cheitlin REVIEW Anthracycline-Induced Cardiotoxicity 47 Shan and others MEDICINE AND PUBLIC ISSUES Physician-Run Health Plans and Antitrust 59 American College of Physicians IN THE BALANCE Mandated Choice for Organ Donation: Time To Give It a Spital Try Who Are the Donors in Organ Donation? The Family’s Klassen and Klassen Perspective in Mandated Choice EDITORIALS Farewell to the “Shy-Drager Syndrome” Schatz Updates and Progress Davidoff Annals of Internal Medicine + Index to Volume 125 V Annals of Internal Medicine Volume 125 Number 2 15 July 1996 ARTICLES Ad Libitum Zinc Gluconate Lozenges for Treating the Common Cold. A Mossad, Macknin, Before Morning Rounds Randomized, Double-Blind, Placebo-Controlled Study Medendorp, and Nez Percés Mason Pre-op Effectiveness and Safety of Intranasal Ipratropium Hayden, Diamond, Bromide in Common Colds. A Randomized, Double-Blind, Wood, Korts, and Letters 152 Placebo-Controlled Trial Wecker The Literature Treatment of Cytomegalovirus Retinitis with Intravitreous Rahhal, Arevalo, of Medicine Cidofovir in Patients with AIDS. Chavez de la Paz, 159 A Preliminary Report Munguia, and others Physicians’ Attitudes about the Care of Patients in the Payne, Taylor, Persistent Vegetative State: A National Survey Stocking, and Sachs BRIEF COMMUNICATIONS Serpentine Thrombus Traversing the Foramen Ovale: Barbour, Izban, Reyes, Paradoxical Embolism Shown by Transesophageal McKiernan, and Louie Echocardiography Management of an Outbreak of Tuberculosis in a Small Allos, Gensheimer, Community Bloch, and others UPDATE Prostate Cancer: Emerging Concepts. Part I Garnick and Fair NIH CONFERENCE Advances in the Management of AIDS-Related Masur, Whitcup, Cytomegalovirus Retinitis Cartwright, and others PERSPECTIVE Whose Death Is It, Anyway? Gilligan and Raffin EDITORIALS Zinc: The Biology and Therapeutics of an Ion Prasad Treatment of Cytomegalovirus Retinitis in Patients with Jabs AIDS Clinical Incoherence about Persons: The Problem of the Cassell Persistent Vegetative State Currents Davidoff ON BEING A PATIENT A Letter from a Patient’s Daughter Hansot VI Annals of Internal Medicine + Index to Volume 125 Annals of Internal Medicine Volume 125 Number 3 1 August 1996 ARTICLES Ad Libitum Lamivudine Plus Zidovudine Compared with Zalcitabine Bartlett, Benoit, The Test Plus Zidovudine in Patients with HIV Infection Johnson, Quinn, Grand Rounds Sepulveda, and others Whispers of Spring Black Women Receive Less Mammography Even with Burns, McCarthy, Similar Use of Primary Care Freund, and others Letters 253 Quinolone-Based Antibacterial Chemoprophylaxis in Bow, Mandell, Louie, Bone Mineral Density in Neutropenic Patients Feld, and others Non-Insulin-Dependent Diabetes The Association between Mortality Rates and Decreased Donnelly, Strieter, Asklepios Concentrations of Interleukin-10 and Interleukin-1 Reid, Kunkel, Burdick, Receptor Antagonist in the Lung Fluids of Patients with Armstrong, Mackenzie, The Literature the Adult Respiratory Distress Syndrome and Haslett of Medicine 255 BRIEF COMMUNICATIONS Serodiagnosis and Monitoring of Aspergillus Infections Tomee, Mannes, van after Lung Transplantation der Bij, and others Effects of Sodium Intake on Albumin Excretion in Bakris and Smith Patients with Diabetic Nephropathy Treated with Long-Acting Calcium Antagonists UPDATES Prostate Cancer: Emerging Concepts. Part II Garnick and Fair Update in Women’s Health Grisso and Ness REVIEW Non-Insulin-Dependent Diabetes Mellitus in Minorities in Carter, Pugh, and the United States Monterrosa ABROAD Heterologous Antisera and Antivenins Are Essential Wilde, Thipkong, Biologicals: Perspectives on a Worldwide Crisis Sitprija, and Chaiyabutr EDITORIALS A Compelling Research Agenda Nickens Can Physicians Diagnose Strengths and Weaknesses in Borowsky, Goertz, and Health Plans? Lurie POSITION PAPER Insurance Reform in a Voluntary System: Implications for American College of the Sick, the Well, and Universal Health Care Physicians ON BEING A DOCTOR The Examination Epstein Annals of Internal Medicine + Index to Volume 125 VII Annals of Internal Medicine Volume 125 Number 4 15 August 1996 ARTICLES Currents I-56 Clinical and Epidemiologic Features of Primary HIV Schacker, Collier, Ad Libitum Infection Hughes, Shea, and Veined Hands Corey The Western Blot Reduced Response to Activated Protein C Is Associated van der Bom, Bots, with Increased Risk for Cerebrovascular Disease Haverkate, and others Letters 344 Safety and Immunogenicity of a Candidate HIV-1 Vaccine Graham, Keefer, Extrahepatic Manifestations of in Healthy Adults: Recombinant Glycoprotein (rgp) 120 McElrath, and others Hepatitis C Virus Infection Self-Assessment of Tuberculin Skin Test Reactions by Prezant, Kelly, Karwa, Diuretics and Sudden Cardiac New York City Firefighters: Reliability and Cost- and Kavanagh Death Effectiveness in an Occupational Health Care Setting B-Blockers and Sudden Cardiac Factors Associated with Do-Not-Resuscitate Orders: Hakim, Teno, Harrell, Death Patients’ Preferences, Prognoses, and Physicians’ Knaus, Wenger, Judgments Phillips, and others Relapsing Group B Streptococcal Infection BRIEF COMMUNICATIONS The Literature Splenectomy Done during Hematologic Remission Crowther, Heddle, of Medicine To Prevent Relapse in Patients with Thrombotic Hayward, Warkentin, 351 Thrombocytopenic Purpura and Kelton Formation of Antibodies to Factor VIII in Patients with Mauser-Bunschoten, Hemophilia A Who Are Treated with Interferon for Damen, Reesink, Chronic Hepatitis C Roosendaal, and others The Urinary Metanephrine-to-Creatinine Ratio for the Héron, Chateilier, Diagnosis of Pheochromocytoma Billaud, and others REVIEWS Diabetic and Hypertensive Heart Disease Grossman and Messerli Atrial Fibrillation: Restoration and Maintenance of Sinus Golzari, Cebul, and Rhythm and Indications for Anticoagulation Therapy Bahler ABROAD Heterosexual Transmission of HIV in Haiti Deschamps and others EDITORIAL Plasma or Urinary Metanephrines for the Diagnosis of Bravo Pheochromocytoma? That Is the Question POSITION PAPER Medical Savings Accounts American College of Physicians ON BEING A DOCTOR The Longest House Call Fournier VIII Annals of Internal Medicine + Index to Volume 125 Annals of Internal Medicine Volume 125. Number 5 1 September 1996 ARTICLES Ad Libitum 418 Relation of Dietary Intake and Serum Levels of Vitamin McAlindon, Felson, Letters 419 D to Progression of Osteoarthritis of the Knee among Zhang, Hannan, Methionine Loading, Vitamin B, Participants in the Framingham Study Aliabadi, and others Status, and Premature Effect of Hormone Replacement Therapy on Bone Mineral Grey, Stapleton, Evans, Thromboembolic Disease Density in Postmenopausal Women with Mild Primary Tatnell, and Reid Aspirin for Asymptomatic Carotid Hyperparathyroidism. A Randomized, Controlled Trial Artery Stenosis A Prognostic Model for Predicting 10-Year Survival in Schuchter, Schultz, Theophylline and Atrioventricular Patients with Primary Melanoma Synnestvedt, and others Block Acyclovir with and without Prednisone for the Treatment Whitley, Weiss, Gnann, Pressure Ulcers of Herpes Zoster. A Randomized, Placebo-Controlled Trial Tyring, Mertz, Pappas, Schleupner, and others Cortical Brain Lesions in Acute Intermittent Porphyria BRIEF COMMUNICATION Relation between Intake of Flavonoids and Risk for Rimm, Katan, The Literature Coronary Heart Disease in Male Health Professionals Ascherio, Stampfer, of Medicine and Willett 429 UPDATE Update in Geriatrics REVIEW War Syndromes and Their Evaluation: From the U.S. Hyams, Wignall, and Civil War to the Persian Gulf War Roswell PERSPECTIVE Predicting Clinical States in Individual Patients Braitman and Davidoff EDITORIAL Hormonal Influences on Bone Remodeling and Bone Loss: Parfitt Application to the Management of Primary Hyperparathyroidism ON BEING A DOCTOR Atonement Paltiel Annals of Internal Medicine + Index to Volume 125 IX Annals of Internal Medicine Volume 125 Number 6 15 September 1996 ARTICLES Currents I-61 Echocardiography for Assessing Cardiac Risk in Patients Halm, Browner, Tubau, Ad Libitum 447 Having Noncardiac Surgery Tateo, and Mangano Letters 514 Piperacillin To Prevent Cholangitis after Endoscopic van den Hazel, Retrograde Cholangiopancreatography Speelman, and others Natural History of Polycythemia Vera A Comparison of the Effect of Universal Use of Gloves Slaughter, Hayden, and Gowns with That of Glove Use Alone on Acquisition Nathan, Hu, Rice, Van Diagnosis of Clostridium difficile of Vancomycin-Resistant Enterococci in a Medical Voorhis, Matushek, Colitis Intensive Care Unit Franklin, and Surgical Treatment of Weinstein Asymptomatic Carotid Stenosis Identifying Adverse Events Caused by Medical Care: Localio, Weaver, Abuse History and Degree of Physician Agreement in a Retrospective Chart Landis, Lawthers, Gastrointestinal Disorders Review Brennan, and others The Literature The Emergence of Neisseria gonorrhoeae with Decreased Gordon, Carlyn, Doyle, of Medicine Susceptibility to Ciprofloxacin in Cleveland, Ohio Knapp, and others 527 BRIEF COMMUNICATIONS Performance Characteristics of a Rapid HIV Antibody Irwin, Olivo, Schable, Assay in a Hospital with a High Prevalence of HIV Weber, Janssen, Ernst, Infection and others Survival and Functional Independence after Impiantation Shen, Hayes, Hammill, of a Permanent Pacemaker in Octogenarians and Bailey, Ballard, and Nonagenarians. A Population-Based Study Gersh Resolution of Heart Failure in Patients with AL Dubrey, Mendes, Amyloidosis Skinner, and Falk UPDATE Oral Manifestations of HIV Infection Weinert and others PERSPECTIVES Prophylaxis for Occupational Exposure to HIV Gerberding Lowering Risk without Lewering Cholesters!: Implications Avins and Browner for National Cholesterol Policy EDITORIALS Antibiotic-Resistant Neisseria gonorrhoeae: The Calm Handsfield and before Another Storm? Whittington Rapid Testing for HIV Antibody: A Technology Whose Spielberg and Kassler Time Has Come ON BEING A DOCTOR Doctor’s Orders Rodowski The Gift Kennedy X Annals of Internal Medicine + Index to Volume 125 Annals of Internal Medicine Volume 125 Number 7 1 October 1996 ARTICLES Letters 621 Effect of Combination Therapy with Lipid-Reducing Drugs Pasternak, Brown, Megatrials for Clinical Decision in Patients with Coronary Heart Disease and “Normal” Stone, Silverman, Making Cholesterol Levels. A Randomized, Placebo-Controlled Gibson, and Sacks Testing with Antineutrophil Trial Cytoplasmic Antibody To Cost-Effectiveness of Interferon-a and Conventional Kattan, Inoue, Giles, Diagnose Wegener Granulomatosis Chemotherapy in Chronic Myelogenous Leukemia Talpaz, and others Use of Bone Densitometry Results Methylprednisolone and Cyclophosphamide, Alone or in Gourley, Austin, Scott, for Decisions about Therapy for Combination, in Patients with Lupus Nephritis. Yarboro, Vaughan, Osteoporosis A Randomized, Controlled Trial Muir, and others Resistance to Thyroid Hormone An Outbreak of Type A Botulism Associated with a Townes, Cieslak, The Literature Commercial Cheese Sauce Hatheway, and others of Medicine BRIEF COMMUNICATIONS 624 Relation between Sodium Balance and Menstrual Cycle Olson, Forman, Lanza, Symptoms in Normal Women McAdam, and others The Pemberton Sign Wallace and Siminoski Update in Neurology Samuels CLINICAL REVIEW Cytomegalovirus Encephalitis Arribas and others REVIEW The Variant Forms of Autoimmune Hepatitis Czaja PERSPECTIVES High-Dose Chemotherapy for Breast Cancer Gradishar and others Surrogate End Points in Clinical Trials: Are We Being Fleming and DeMets Misled? EDITORIALS Interferons: Effectiveness, Toxicities, and Costs Borden and Parkinson Botulinum Toxin: A Deadly Poison Sheds Its Negative Simpson Image ON BEING A DOCTOR Balancing Family and Career: Advice from the Trenches Annals of Internal Medicine + Index to Volume 125 XI Annals of Internal Medicine Volume 125 Number 8 15 October 1996 ARTICLES Currents [I-55 Withdrawing Life Support from Mechanically Ventilated Rubenfeld and Ad Libitum 694 Recipients of Bone Marrow Transplants: A Case for Crawford Evidence-Based Guidelines Letters 695 Hepatitis C Virus Genotypes in the United States: Zein, Rakela, Krawitt, Midline Catheterization in Epidemiology, Pathogenicity, and Response to Interferon Reddy, Tominaga, Hospitalized Patients Therapy Persing, and others Efficacy of Holter Monitors Important Elements of Outpatient Care: A Comparison of Laine, Davidoff, Lewis, Bell Palsy and Herpes Simplex Patients’ and Physicians’ Opinions Nelson, and others Virus Diagnosis of 22 New Cases of Bartonella Endocarditis Raoult and others Ribavirin for Chronic Hepatitis C BRIEF COMMUNICATION Treatment of a-1-Antitrypsin Deficiency, Massive Edema, and Association of Fibrinogen with Glycemic Control and Bruno, Cavallo-Perin, Panniculitis with a-1 Protease Albumin Excretion Rate in Patients with Bargero, Borra, Inhibitor Non-Insulin-Dependent Diabetes Mellitus D’Errico, and Pagano Effect of Ethinyl Estradiol on UPDATE Chronic Active Hepatitis Hepatitis C 658 Sharara The Literature MEDICINE AND PUBLIC ISSUES of Medicine 702 Medical Futility: Response to Critiques 669 Schneiderman, Jecker, and Jonsen PERSPECTIVES The Medicalization of Race: Scientific Legitimization of a Witzig Flawed Social Construct Immunologic Dissonance: A Continuing Evolution in Our Bone Understanding of the Systemic Inflammatory Response Syndrome (SIRS) and the Multiple Organ Dysfunction Syndrome (MODS) EDITORIALS Odds and Ends: Trust and the Debate over Medical Caplan Futility Everyone Sang Davidoff ON BEING A DOCTOR The Bet Novack XII Annals of Internal Medicine + Index to Volume 125 Annals of Internal Medicine Volume 125 Number 9 1 November 1996 ARTICLES Ad Libitum Effects of Lamivudine on Replication of Hepatitis B Virus Benhamou, Katlama, Ten Years Later in HIV-Infected Men Lunel, and others Teaching CPR Twenty-Year Dynamics of Serum Cholesterol Levels in the Jousilahti, Vartiainen, Letters 776 Middle-Aged Population of Eastern Finland Tuomilehto, and Puska Chemotherapy plus Radiotherapy Compared with Pritchard and Anthony Acyclovir Suppresses Subclinical Radiotherapy Alone in the Treatment of Locally Advanced, Shedding of Herpes Simplex Virus Unresectable, Non—Small-Cell Lung Cancer. Trends in Infectious Disease and A Meta-Analysis Cancer in HIV Infection Prevalence and Sources of Patients’ Unmet Expectations Kravitz, Callahan, Hyperkalemia and for Care Paterniti, and others Trimethoprim-Sulfamethoxazole BRIEF COMMUNICATIONS Allogeneic Bone Marrow Transplantation in Chronic Subfulminant Liver Failure and Severe Hepatotoxicity Schiano, Bellary, Lymphocytic Leukemia Caused by Loratadine Use Cassidy, and others Shark Cartilage-Induced Hepatitis Effect of Hepatitis G Virus Infection on Chronic Hepatitis Tanaka, Alter, Cc Nakatsuji, and others The Literature UPDATE of Medicine 783 Update in Allergy and Immunology Condemi REVIEW Acute Myocardial Infarction Associated with Pregnancy Roth and Elkayam PERSPECTIVE Physician Recommendations and Patient Autonomy: Quill and Brody Finding a Balance between Physician Power and Patient Choice EDITORIALS The Virtue of Qualitative and Quantitative Research Inui Hepatitis G Virus Infection: A Work in Progress Di Bisceglie ON BEING A DOCTOR April May Be Cruel, but November’s Pretty Lousy, Too Siegler Annals of Internal Medicine + Index to Volume 125 XIil Annals of Internal Medicine Volume 125 Number 10 15 November 1996 ARTICLES Currents = I-65 Importance of Findings on the Initial Evaluation for Cornuz, Pearson, Ad Libitum 857 Cancer in Patients with Symptomatic Idiopathic Deep Creager, Cook, and Venous Thrombosis Goldman Letters 858 Sporadic Urban Leptospirosis Vinetz and others Vancomycin-Resistant Staphylococcus aureus Outbreak of Invasive Mycoses Caused by Paecilomyces Orth, Frei, Itin, lilacinus from a Contaminated Skin Lotion Rinaldi, Speck, and Hypernatremia in Hospitalized others Patients Patterns of Ordering Diagnostic Tests for Patients with Carey, Garrett, Hemorrhagic Proctosigmoiditis Acute Low Back Pain and others and Blastocystis hominis Risk for Subsequent Cancer after Diagnosis of Basal-Cell Frisch, Hjalgrim, Olsen, Neurotoxicity and Tretinoin Carcinoma. A Population-Based, Epidemiologic Study and Melbye The Literature BRIEF COMMUNICATION of Medicine 862 Body Cavity-Based Malignant Lymphoma Containing Strauchen, Hauser, Kaposi Sarcoma-Associated Herpesvirus in an Burstein, Jimenez, HIV-Negative Man with Previous Kaposi Sarcoma Moore, and Chang REVIEW Occupationally Acquired Infections in Health Care Sepkowitz Workers. Pari I ABROAD I’ve Been Where It’s Gone, So I Know What I Got... 835 Hardison An American Fulbright Lecturer in Albania, 1994-1995 MEDICINE AND PUBLIC ISSUES Quality Comes Home 839 Berwick PERSPECTIVE Are All Diseases Infectious? EDITORIAL Basal-Cell Carcinoma of the Skin: A Harbinger of Schottenfeld Cutaneous and Noncutaneous Multiple Primary Cancer ON BEING A PATIENT My Not-So-Near-Death Experience XIV Annals of Internal Medicine + Index to Volume 125