Anemia of Chronic Disease - G. Weiss, et. al., (CRC, 2005) WW

782 Pages·2005·8.25 MB·English

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Contents

Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xiii

Introduction: Anemia of Chronic Disease:
The Enigma and the Challenge
Chaim Hershko, Victor R. Gordeuk and Gu€nter Weiss . . xvii

PART I: BASICS

1. Regulation of Iron Metabolism
. . . . . . . . . . . . .
1
Kostas Pantopoulos
Biology of Iron . . . .
1
Iron’s Toxicity . . . .
3
Iron Distribution in the Body . . . .
5
Biomedical Aspects of Iron Metabolism . . . .
5
Mechanisms for Dietary Iron Absorption and Erythroid
Iron Utilization . . . .
8
Regulation of Dietary Iron Absorption and Erythroid Iron
Utilization . . . .
13
Cellular Iron Uptake . . . .
17
Intracellular Iron Storage . . . .
22
iii