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Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.: Proceedings of the 21st Postgraduate Course in Critical Care Medicine Venice-Mestre, Italy — November 10–13, 2006 PDF

468 Pages·2007·4.16 MB·English
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A. Gullo(Editor) Anaesthesia, Pain, Intensive Care and Emergency – A.P.I.C.E. Proceedingsofthe 21stPostgraduateCourseinCriticalCareMedicine Venice-Mestre,Italy–November10-13,2006 A. Gullo (Editor) Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E. Proceedings of the 21st Postgraduate Course in Critical Care Medicine Venice-Mestre, Italy – November 10-13, 2006 Springer ANTONINOGULLO,M.D. Head,DepartmentofAnaesthesiaandIntensiveCare Head,PostgraduatedSchoolofAnaesthesiaandIntensiveCare CataniaUniversityHospital Catania,Italy LibraryofCongressControlNumber:2006935691 ISBN1088-470-0570-1 SpringerMilanBerlinHeidelbergNewYork ISBN13978-88-470-0570-9SpringerMilanBerlinHeidelbergNewYork Thisworkissubjecttocopyright.Allrightsarereserved,whetherthewholeorpartofthematerial isconcerned,specificallytherightsoftranslation,reprinting,reuseofillustrations,recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplicationofthispublicationorpartsthereofispermittedonlyundertheprovisionsofthe ItalianCopyrightLawinitscurrentversion,andpermissionforusemustalwaysbeobtainedfrom Springer.ViolationsareliabletoprosecutionundertheItalianCopyrightLaw. SpringerisapartofSpringerScience+BusinessMedia springer.com ©Springer-VerlagItalia2007 PrintedinItaly Theuseofgeneraldescriptivenames,registerednames,trademarks,etc.inthispublicationdoes notimply,evenintheabsenceofaspecificstatement,thatsuchnamesareexemptfromthe relevantprotectivelawsandregulationsandthereforefreeforgeneraluse. Productliability:Thepublisherscannotguaranteetheaccuracyofanyinformationaboutdosage and application contained in this book. In every individual case the user must check such informationbyconsultingtherelevantliterature. Coverdesign:SimonaColombo Typesettingandprinting:ArtiGraficheStella,Trieste,Italy V Table of Contents ETHICS Chapter1–DyingintheIntensiveCareUnit K.HILLMAN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 LUNG Chapter2–Geneticsandmolecularbiologyinacutelunginjury R.VASCHETTO,J.HAITSMA,H.ZHANG . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Chapter3–Lung,respiratorymechanics,artificialventilation A.KOUTSOUKOU,J.MILIC-EMILI. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Chapter4–Thepressure-volumecurve V.R.CAGIDO,W.A.ZIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Chapter5–Methodsforassessingexpiratoryflowlimitationduringtidalbreathing N.G.KOULOURIS,S.-A.GENNIMATA,A.KOUTSOUKOU . . . . . . . . . . . . . . . . . . 41 Chapter6–Howtoventilatebrain-injuredpatientsinrespiratoryfailure P.PELOSI,P.SEVERGNINI,M.CHIARANDA . . . . . . . . . . . . . . . . . . . . . . . . 53 Chapter7–Helpingsurgicalpatientstogiveupsmoking D.O.WARNER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 Chapter8–Respiratoryissuesandventilatorystrategiesformorbidlyobesepatients J.SPRUNG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 FLUIDANDELECTROLYTEEMERGENCY Chapter9–Fluidandelectrolyteemergency J.BOLDT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 VI Chapter10–Electrolyteemergencies,aniongap,osmolality F.SCHIRALDI,G.GUIOTTO,L.MORELLI . . . . . . . . . . . . . . . . . . . . . . . . . 97 Chapter11–Acuterenalfailure M.PALAZZO. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 Chapter12–Acuteliverfailure P.FELTRACCO,M.L.BREZZI,C.ORI . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 INFECTIONSANDSEPSIS Chapter13–Pneumoniainventilatedpatients.SevereGramnegativeinfections; theimpactonmortalityanditsprevention D.F.ZANDSTRA,H.K.F.VANSAENE . . . . . . . . . . . . . . . . . . . . . . . . . . . 143 Chapter14–Gram-positiveventilator-associatedpneumonia:impactonmortality A.R.DEGAUDIO,S.RINALDI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155 Chapter15–FungalinfectionsintheICU A.DEGASPERI,A.CORTI,L.PERRONE . . . . . . . . . . . . . . . . . . . . . . . . . . 163 Chapter16–Focusonthediagnosisandtreatmentofseveremeningitis R.LUZZATI,D.GIACOMAZZI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171 Chapter17–Plasmafiltrationinsepsis:aresearchprotocol S.LIVIGNI,M.MAIO,G.BERTOLINI . . . . . . . . . . . . . . . . . . . . . . . . . . . 181 HIGHLIGHTSONCIRCULATORYFAILURE,CPRANDTRAUMA Chapter18–Thecellinshock M.M.MORALES,H.PETRS-SILVA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191 Chapter19–Tissuepartialpressureofcarbondioxidetensionmeasurements andmicrocirculationvisualisation.Newtechniquesforthestudyoflowflowstates G.RISTAGNO,W.TANG,M.H.WEIL . . . . . . . . . . . . . . . . . . . . . . . . . . . 203 Chapter20–Ventricularfibrillationanddefibrillation:contemporaryunderstanding ofmechanisms R.D.WHITE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 VII Chapter21–Arterialwaveformanalysistodeterminecardiovascularparameters S.SCOLLETTA,B.BIAGIOLI,P.GIOMARELLI . . . . . . . . . . . . . . . . . . . . . . . . 225 Chapter22–TheUtsteinstyleforthereportingofdatafromcardiacarrest J.P.NOLAN,C.L.GWINNUTT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237 Chapter23–Challengesintraumacare P.D.LUMB . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 247 Chapter24–Advancesintraumacare F.PLANI,J.GOOSEN. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257 PERIOPERATIVEMEDICINE Chapter25–Standardsofcareinoperatingtheatres F.GRÜNE,T.OTTENS,M.KLIMEK . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281 Chapter26–Audit M.KLIMEK,F.GRÜNE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 291 Chapter27–Focusonentropyandsurgicalstressindex M.SORBELLO,S.MANGIAMELI,A.GULLO. . . . . . . . . . . . . . . . . . . . . . . . . 301 Chapter28–Neuraxialanaesthesiaandanticoagulation D.J.WEDEL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319 Chapter29–Regionalanaesthesiainthepatientwithpre-existing neurologicaldysfunction T.T.HORLOCKER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 325 Chapter30–Infectiouscomplicationsofregionalanaesthesia D.J.WEDEL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337 Chapter31–TheMayoClinictotaljointanalgesicpathway T.T.HORLOCKER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345 Chapter32 –Acutetherapyinpatientswithwide-QRScomplextachyarrhythmias R.D.WHITE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353 VIII OBSTETRICSANDPAEDIATRICS Chapter33–Obstetricsathighrisk R.ALEXANDER,N.VOLPE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365 Chapter34–Resuscitationofthenewborn D.TREVISANUTO,N.DOGLIONI,F.MARIO . . . . . . . . . . . . . . . . . . . . . . . . 377 Chapter35–Regionalanaesthesiainneonates M.ASTUTO,D.SAPIENZA,G.RIZZO . . . . . . . . . . . . . . . . . . . . . . . . . . . 385 Chapter36–Locoregionalanaesthesiainchildren N.DISMA,G.ROSANO,D.LAURETTA . . . . . . . . . . . . . . . . . . . . . . . . . . . 397 Chapter37–ManagementofCRRTinpaediatrics G.ZOBEL,S.RÖDL,E.RING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405 Chapter38–Severityscoresinpaediatricintensivecareunits I.SALVO,A.WOLFLER,A.MANDELLI. . . . . . . . . . . . . . . . . . . . . . . . . . . 413 Chapter39–Analgesiaandsedationduringmechanicalventilationinpaediatrics ML.MASSONE,L.MANFREDINI,G.OTTONELLO . . . . . . . . . . . . . . . . . . . . . 421 COMPUTING Chapter40–Latencyreductioninclinicalandtranslationalresearch C.-H.HUANG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 437 CRITICALCAREBLEEDING Chapter41–Newfrontiersincriticalbleeding S.BUSANI,L.DONNO,M.GIRARDIS . . . . . . . . . . . . . . . . . . . . . . . . . . .449 Chapter42–EvaluationofperformanceofICUs J.R.LEGALL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 455 IX List of Contributors AlexanderR. ChiarandaM. DepartmentofAnaesthetics,Worcester- DepartmentfortheEnvironment,Health shireRoyalHospital,Worcester(UK) andSafety,UniversityofInsubria– AnaesthesiaandIntensiveCareUnitB, AstutoM. DistrictHospitalandMacchiFoundation, DepartmentofAnaesthesiaandIntensive Varese(Italy) Care,PostgraduateSchoolofAnaesthesia andIntensiveCare,CataniaUniversity CortiA. Hospital,Catania(Italy) 2ndAnaesthesia,IntensiveCareandAb- dominalTransplantationUnit,Niguarda BertoliniG. Ca’GrandaHospital,Milan(Italy) GiViTICoordinatingCentre,Laboratory ofClinicalEpidemiology,“MarioNegri” DeGasperiA. InstituteforPharmacologicalResearch, 2ndAnaesthesia,IntensiveCareandAb- Ranica-BG(Italy) dominalTransplantationUnit,Niguarda Ca’GrandaHospital,Milan(Italy) BiagioliB. DepartmentofCardiothoracicAnaesthe- DeGaudioA.R. siaandIntensiveCareUnit,Universityof DepartmentofCriticalCare,Sectionof Siena(Italy) AnaesthesiologyandCriticalCare,Uni- versityofFlorence(Italy) BoldtJ. DepartmentofAnaesthesiologyandIn- DismaN. tensiveCareMedicine,Klinikumder DepartmentofAnaesthesiaandIntensive StadtLudwigshafen(Germany) Care,CataniaUniversityHospital, Catania(Italy) BrezziM.L. DepartmentofPharmacologyand DoglioniN. AnaesthesiologyUniversityHospitalof PaediatricDepartment,SchoolofMedi- Padua(Italy) cine,UniversityofPadua,AziendaOspe- dalieraPadua(Italy) BusaniS. AnaesthesiaandIntensiveCareUnitI, DonnoL. ModenaUniversityHospitalandModena AnaesthesiaandIntensiveCareUnitI, andReggioEmiliaUniversity(Italy) ModenaUniversityHospitalandModena andReggioEmiliaUniversity(Italy) CagidoV.R. LaboratoryofRespirationPhysiology, FeltraccoP. CarlosChagasFilhoInstituteofBiophy- DepartmentofPharmacologyand sics,FederalUniversityofRiodeJaneiro AnaesthesiologyUniversityHospitalof (Brazil) Padua(Italy) X GennimataS.-A. HorlockerT.T. RespiratoryFunctionLaboratory,Depart- DepartmentofAnesthesiologyandOrtho- mentofRespiratoryMedicine,University pedics,MayoClinicCollegeofMedicine, ofAthensMedicalSchool,“Sotiria”Hos- Rochester,Minnesota(USA) pital,Athens(Greece) HuangC.-H. GiacomazziD. DepartmentofComputerScienceandEn- InfectiousDiseasesUnit,UniversityHos- gineering,UniversityofConnecticut pitalofTrieste,Trieste(Italy) (USA) GiomarelliP. KlimekM. DepartmentofAnaesthesiaandIntensive ErasmusMC,DepartmentofAnaesthesio- CareUnit,UniversityofSiena(Italy) logy,Rotterdam(TheNetherlands) GirardisM. KoulourisN.G. AnaesthesiaandIntensiveCareUnitI, RespiratoryFunctionLaboratory,Depart- ModenaUniversityHospitalandModena mentofRespiratoryMedicine,University andReggioEmiliaUniversity(Italy) ofAthensMedicalSchool,“Sotiria”Hos- pital,Athens(Greece) GoosenJ. TraumaUnit,JohannesburgHospital,Di- KoutsoukouA. visionofTraumaandCriticalCare,De- CriticalCareDepartment,GeneralEvan- partmentofSurgery,Universityofthe gelismosHospital,MedicalSchool,Uni- Witwatersrand,Johannesburg(South versityofAthens(Greece) Africa) LaurettaD. GrüneF. DepartmentofAnaesthesiaandIntensive ErasmusMC,DepartmentofAnaesthesio- Care,“Policlinico”UniversityHospital, logy,Rotterdam(TheNetherlands) Catania(Italy) GuiottoG. LeGallJ.R. EmergencyMedicineDivision,S.Paolo IntensiveCareUnit,HôpitalSaintLouis, Hospital,Naples(Italy) Paris(France) GulloA. LivigniS. DepartmentofAnaesthesiaandIntensive DepartmentofAnaesthesiaandIntensive Care,PostgraduateSchoolofAnaesthesia Care,OspedaleTorinoNordEmergenza andIntensiveCare,CataniaUniversity SanGiovanniBosco,Turin(Italy) Hospital,Catania(Italy) LumbP.D. GwinnuttC.L. DepartmentofAnesthesiology,Keck DepartmentofAnaesthesia,Salford Schoolof MedicineatUSC, RoyalHospitalsNHSTrust,HopeHospi- LosAngeles(USA) tal,Salford(UK) LuzzatiR. HaitsmaJ.J. InfectiousDiseasesUnit,University InterdepartmentalDivisionofCritical HospitalofTrieste,Trieste(Italy) CareMedicine,UniversityofToronto,St. Michael’sHospital,Toronto,Ontario MaioM. (Canada) DepartmentofAnaesthesiaandIntensive Care,OspedaleTorinoNordEmergenza HillmanK. SanGiovanniBosco,Turin(Italy) AreaCriticalCareServices,Liverpool Hospital,Liverpool,NSW(Australia)

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Developing sectors in the Intensive Care field – and in Critical Care Medicine in general – require specific levels of competence having a same common denominator: an in-depth knowledge of human pathophysiology. Although this volume presents plenty of topics in constant evolution, as witnessed b
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