Neuropsychiatric Disorders Koho Miyoshi Yasushi Morimura ● Kiyoshi Maeda Editors Neuropsychiatric Disorders Editors Koho Miyoshi, M.D., Ph.D. Yasushi Morimura, M.D, Ph.D. Director Chief Executive Officer Jinmeikai Research Institute for Mental Jinmeikai Foundation and Hospital Health 53-20 Kabutoyama-cho, Nishinomiya 53-20 Kabutoyama-cho, Nishinomiya Hyogo 662-0001, Japan Hyogo 662-0001, Japan Ohmura Hospital The former Professor 200 Kitayama-Ohmura, Miki Department of Neuropsychiatry Hyogo 673-0404, Japan Kyoto University Graduate School of Medicine Kyoto, Japan Kiyoshi Maeda, M.D., Ph.D. Professor Department of Occupational Therapy Kobe Gakuin University School of Rehabilitation 518 Ikawadani-cho, Nishi-ku Kobe 651-2180, Japan ISBN 978-4-431-53870-7 e-ISBN 978-4-431-53871-4 DOI 10.1007/978-4-431-53871-4 Springer Tokyo Dordrecht Heidelberg London New York Library of Congress Control Number: 2010924621 © Springer 2010 This work is subject to copyright. 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Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) Preface Neuropsychiatry is an integrating neuroscience of neurology and psychiatry that aims to investigate the psychiatric symptoms of neurological disorders as well as the neurobiological bases of psychiatric disorders, including organic mental disor- ders and endogenous psychoses. Additionally, neuropsychiatry aims to prevent or reduce the suffering of individuals with the psychiatric symptoms of cerebral disorders. The International Organization of Neuropsychiatry (ION), the forerunner of the current association, was established in Seville in 1996 and was reorganized as the International Neuropsychiatric Association (INA) in Toronto in 1998. Since then, it has continued to provide a forum for exchanging knowledge acquired by scientific activities in the field to accomplish the purposes of the association. Toward that end, international congresses have been held every 2 years in cities around the world: Seville (1996), Toronto (1998), Kyoto (2000), Buenos Aires (2002), Athens (2004), Sydney (2006), and Cancun (2008). In addition to the international congresses, regional congresses of neuropsychiatry have been organized regularly in Europe and Latin America. All the meetings have been successful and fruitful in stimulating progress in neuropsychiatry. As one of the results of the meetings, the monograph Contemporary Neuropsychiatry was published by Springer Japan in 2001. This present monograph consists of papers from the Kobe Conference of the International Neuropsychiatric Association, which was held by the International Neuropsychiatric Association in collaboration with the Jinmeikai Foundation and the Japan Neuropsychiatric Association in Kobe, September 12–13, 2009. The meeting was originally planned to be a semi-closed workshop for the publication of this monograph in neuropsychiatry. Because the meeting was organized to be held between two international congresses of neuropsychiatry – the 7th INA Congress in Cancun (2008) and the 8th INA Congress in Chennai (2011) – it was planned so as to concentrate on rather limited areas of neuropsychiatry, namely, the clinical aspects of neuropsychiatric disorders. As the editors, we are confident that this publication will stimulate further progress and research in neuropsychiatry in all parts of the world. We express our heartfelt gratitude for the contributions by all the authors who attended the meeting and sub- mitted papers. We are very pleased to have received their excellent work in neurop- sychiatry for this publication. We express our special appreciation to Dr. Perminder Sachdev, who allowed us to publish “The Core Curriculum of Neuropsychiatry,” v vi Preface which originally appeared on the website of the International Neuropsychiatric Association in 2004, for standardizing the guidelines of training in neuropsychiatry. We would like to acknowledge the support for the Kobe Conference of the International Neuropsychiatric Association by the Jinmeikai Foundation, Ohmura Hospital, the Federation of Pharmaceutical Manufacturers Association of Japan, the Osaka Pharmaceutical Manufacturers Association, Kaiseikai (Japan Psychiatric Association for Partnership), the Kobe Convention and Visitors Association, the Tsutomu-Nakauchi Foundation, Japan Eisai Pharmaceutical Company, Japan Pfizer Pharmaceutical Company, Japan Janssen Pharmaceutical Company, and Japan Eli Lilly Pharmaceutical Company. Koho Miyoshi, M.D., Ph.D. Yasushi Morimura, M.D., Ph.D. Kiyoshi Maeda, M.D., Ph.D. Editors Contents Part I Introduction Clinical Manifestations of Neuropsychiatric Disorders .............................. 3 Koho Miyoshi and Yasushi Morimura Part II Neuropsychiatric Syndromes Thyroid–Brain Interactions in Neuropsychiatric Disorders ....................... 19 Robertas Bunevičius and Arthur J. Prange, Jr. Lack of Insight and Awareness in Schizophrenia and Neuropsychiatric Disorders .................................................................... 33 James Gilleen, Kathryn Greenwood, and Anthony S. David Visual Hallucinations in Neurodegenerative Disorders ............................... 51 Spyridon Papapetropoulos and Blake K. Scanlon Organic Delusional Syndrome: Tentative Neuropsychological Mechanism of Delusions ................................................................................. 65 Yoshitaka Ohigashi and Makiko Yamada Neurological and Psychological Forms of Amnesia ..................................... 77 Michael D. Kopelman Part III Seizure Disorders The Neuropsychological Aspect of Epilepsy ................................................. 95 Yoshio Morita The Interictal Dysphoric Disorder of Epilepsy ............................................ 103 Marco Mula vii viii Contents Neuropsychiatric Symptoms of Seizure Disorders with Special Reference to the Amygdala....................................................... 113 Michael Trimble Part IV Traumatic Brain Injury Neuropsychiatric Assessment of Traumatic Brain Injury During Acute Neurorehabilitation ................................................................ 125 David B. Arciniegas Part V Vascular and Inflammatory Disorders Neuropsychiatric Aspects of Vascular Cognitive Impairment .................... 149 Ingmar Skoog Neuropsychiatric Complications of Cerebrovascular Disease .................... 163 Moises Gaviria and Rhonda DePaul Verzal Systemic Inflammation and Cognition in the Elderly ................................. 177 Julian Trollor and Emmeline Agars Part VI Neurodegenerative Disorders Diagnosis and Clinical Relevance of Depression and Apathy in Alzheimer’s Disease .................................................................................... 201 Sergio E. Starkstein and Simone Brockman Cognitive Decline and Treatment of Alzheimer’s Disease ........................... 213 Luis Ignacio Brusco Alzheimer’s Disease in Japan: Current Situation and Issues of the Care for Persons with Dementia ....................................... 227 Akira Homma AD-FTLD Spectrum: New Understanding of the Neurodegenerative Process from the Study of Risk Genes............... 235 Masatoshi Takeda, Takashi Kudo, Toshihisa Tanaka, Masayasu Okochi, Ryota Hashimoto, Takashi Morihara, and Shinji Tagami Dementia with Lewy Bodies ........................................................................... 247 Ian Grant McKeith Dementia with Lewy Bodies and Parkinson Disease with Dementia Within the Spectrum of Lewy Body Disease ...................... 255 Kenji Kosaka Contents ix Clinicopathological Characterization of Frontotemporal Lobar Degeneration ........................................................................................ 261 Yoshio Mitsuyama Diffuse Neurofibrillary Tangles with Calcification ...................................... 271 Shigetoshi Kuroda, Hideki Ishizu, Seishi Terada, Osamu Yokota, Yasuyuki Tanabe, and Takashi Haraguchi Part VII Topics of Neuropsychiatric Disorders Ayahuasca: Current Interest in an Ancient Ritual ...................................... 281 Eduardo Gastelumendi The Molecular Genetics of Suicide ................................................................ 287 Kiyoshi Maeda, Osamu Shirakawa, Naoki Nishiguchi, and Masaaki Fukutake Part VIII International Neuropsychiatric Association Brief History and Current Status of the International Neuropsychiatric Association......................................................................... 301 Koho Miyoshi Core Curriculum in Neuropsychiatry of the International Neuropsychiatric Association......................................................................... 317 Perminder Sachdev and The Curriculum Committee of the International Neuropsychiatric Association Index ................................................................................................................. 347
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