Table Of Content

Contents VOLUME 8 NUMBER 1 FEBRUARY Editorial 95 Three months of ocreotide treatment decreases Review article: infectious diarrhoea. gastric acid secretion and argyrophil cell density in H. L. DUPONT patients with Zollinger—Ellison syndrome and antral Review article: controversies in NSAID-induced G-cell hyperfunction. B. ANNIBALE, gastroduodenal damage—do they matter ? G. DELLE FAVE, C. AZZONI, V. CORLETO, G. C. FENN G. CAMBONTI, G. D’AMBRA, F. P. PILATO Mesalamine capsules enhance the quality of life for & C. BORDI patients with ulcerative colitis. Rolling review: disorders of gastrointestinal M. ROBINSON, S. HANAUER, R. HOOP, motility—therapeutic potentials and limitations. A. ZBROZEK & C. WILKINSON K.-A. GWEE & N. W. READ Oral mesalazine (5-aminosalicylic acid; Asacol) for Short report: treatment of gastric ulcer with the prevention of post-operative recurrence of lansoprazole or ranitidine—a multicentre clinical Crohn’s disease. R. CAPRILLI, A. ANREOLI, trial. P,.M ICHEL, M. LEMAIRE, R. COLIN, L. CAPURSO, G. CORRAO, G. D’ ALBASIO, G. BOMMELAER, J. C. RAMBAUD, A. GIOIENI, G. ASSUERO LANFRANCHI, J. L. DUPAS, M. A. BIGARD I. PALADINI, F. PALLONE, V. PONTI, & J.C. VERWAERD G. P. RIGO, F. P. ROSSINI, G. C. STURNIOLO, Short report: a comparative study of the F. TONELLI, D. VALPIANI & THE GRUPPO interaction between antacid and H,-receptor ITALIANO PER LO STUDIO DEL COLON E antagonists. DEL RETTO (GISC) T. J. SULLIVAN, J. H. REESE, L. JAUREGUI, Lack of evidence of neurotoxicity following 8 weeks K. MILLER, L. LEVINE & K. AAB ACHMANN of treatment with tripotassium dicitrato Short report: zinc sulphate supplementation bismuthate. C. U.N WOKOLO, J. D. corrects abnormal erythrocyte membrane long- FITZPATRICK, R. PAUL, R. DYAL, chain fatty acid composition in patients with B. J. SMITS & D. E. LOFT Crohn’s disease. A.B ELLUZZI, C. BRIGNOLA, Famotidine increases plasma alcohol concentration M. CAMPIERI, P. GIONCHETTI, F. RIZZELLO, in healthy subjects. S. BOSCHI, S. CUNANNE, M. MIGLIOLI D. B. BURNHAM, D. MILLER, R. KARLSTADT, & L. BARBARA C. J. FRIEDMAN & R. H. PALMER Short report: clarithromycin, an alternative to Effect of propranolol on prevention of first variceal metronidazole in the triple therapy of Helicobacter bleed and survival in patients with chronic liver pylori infection. J. C. THIJS, A.A . VAN ZWET, disease. J. N. PLEVRIS, R. ELLIOT, P. R. MILLS, W. MOOLENAAR, J. A. J. OOM, H. DE KORTE W. S. HISLOP, J. M. DAVIES, & E. A.R UNHAAR I. A. D. BOUCHIER & P. C. HAYES 5 Short report: long-term management of peptic Randomized, placebo-controlled comparison of ulcer disease with ranitidine in Germany. famotidine 20 mg b.d. or 40 mg b.d. in patients B. SIMON, E. SCHUTZ, P. MULLER with erosive oesophagitis. T. J. SIMON, M. M. & J. S. DIXON BERENSON, R. G. BERLIN, S. SNAPINN Letter to the Editors. F.H ALTER & C. RUCHTI & A. CAGLIOLA Comparison of pantoprazole and ranitidine in the treatment of acute deodenal ulcer. G. JUDMAITER, H. R. KOELZ & PANTOPRAZOLE-DUODENAL ULCER STUDY GROUP Zollinger—Ellison syndrome and antral G-cell hyperfunction in patients with resistant duodenal ulcer disease. B. ANNIBALE, L. DE MAGISTRIS, V. CORLETO, G. D’AMBRA, M. MARIGNANTI, C. IANNONI & G. DELLE FAVE Contents VOLUME 8 NUMBER 2 APRIL Review article: aspirin and gastrointestinal Comparative effects of H,-receptor antagonists on bleeding. C. J. HAWKEY subjective and objective assessments of sleep. 7 Review article: drug therapy for reflux W. C. ORR, J. C. DUKE, N. K. IMES oesophagitis. & M. H. MELLOW W. A. DE BOER & G.N. J. TYTGAT Addition of cisapride shortens colonoscopy Influence of antidepressants on whole gut and preparation with lavage in elderly patients. orocaecal transit times in health and irritable S. UEDA, H. IISHI, M. TATSUTA, K. ODA bowel syndrome. D. A. GORARD, G. W. LIBBY &S. OSAKA & M. J. G. FARTHING Rapid healing of gastric ulcers with lansoprazole. Effect of eradication of Helicobacter pylori on gastric K. D. BARDHAN, J. AHLBERG, W. S. HISLOP, epithelial cell proliferation. A. G. FRASER, C. LINDHOLMER, R. G. LONG, A. G. R. SIM, E. A. SANKEY, A. P. DHILLON MORGAN, S. SJOSTEDT, P. M. SMITH, R. & R. E. POUNDER STIG, K. G.W ORMSLEY, H. LANGWORTHY Phospholipase A, activity in gastric juice from & I. K. MOULES patients with active and H. pylori-eradicated healed Effect of enprostil on serum gastrin and pepsinogen duodenal ulcer. K. BERSTAD, R. SJODAHL A and C levels in patients on long-term treatment & A. BERSTAD with omeprazole. J. L. MEIJER, J. B. M. J. Preservation of gastric antral mucus is associated JANSEN, I. BIEMOND, I. J. KUIJPERS with failure of eradication of Helicobacter pylori by & C. B. H.W . LAMERS bismuth, metronidazole and tetracycline. Rolling review—the pathogenesis, diagnosis and A. J. LOBO, C. A.M. MCNULTY, J. S. UFF, management of viral hepatitis. G. M.D USHEIKO J. DENT, I. A.E YRE-BROOK Short report: Prednisolone metasulphobenzoate & S. P. WILKINSON foam retention enemas suppress the hypothalamo- 7 Activity of metronidazole, azithromycin and three pituitary-adrenal axis. W. LUMAN, R. S. GRAY, benzimidazoles on Giardia lamblia growth and R. PENDEK & K. R. PALMER attachment to a human intestinal cell line. Short report: omeprazole-—tetracycline P. H. KATELARIS, A. NAEEM combinations are inadequate as therapy for & M. J. G. FARTHING Helicobacter pylori infection. M. T. AL-ASSI, R. M. Comparison of acid inhibition by either oral high- GENTA &D. Y. GRAHAM dose ranitidine or omeprazole. S.H URLIMANN, Letter to the Editors. G. D. KERR B. ABBUHL, W. INAUEN & F. HALTER Contents VOLUME 8 NUMBER 3 JUNE 265 Review article: gastro-oesophageal reflux and Effective treatment after failure of omeprazole laryngeal symptoms. A. G. FRASER plus amoxycillin to eradicate Helicobacter pylori Review article: the transjugular intrahepatic infection in peptic ulcer disease. J. LABENZ, portosystemic shunt (TIPS) in the treatment of G. H. RUHL, J. BERTRAMS & G. BORSCH portal hypertension. P. A. McCORMICK, R. DICK Comparative effects of intraduodenal psyllium & A. K. BURROUGHS and senna on canine small bowel motility. Effect of decaffeination of coffee or tea on gastro- W. ASHRAF, J. LOF, G. JIN & E. M. M. QUIGLEY oesophageal reflux. B. WENDL, A. PFEIFFER, Flumecinol for the treatment of pruritus C. PEHL, T. SCHMIDT & H. KAESS associated with primary biliary cirrhosis. Comparative bioavailability of 5-aminosalicylic I. B. TURNER, M. D. RAWLINS, P. WOOD acid from a controlled release preparation and & O. F. W. JAMES an azo-bond preparation. L. A.C HRISTENSEN, Short report: the effect of misoprostol on the J. FALLINGBORG, B. A. JACOBSEN, anaemia of NSAID enteropathy. A. J. MORRIS, K. ABILDGAARD, H. H. RASMUSSEN, L. MURRAY, R. D. STURROCK, R. MADHOK, S. H. HANSEN & S. N. RASMUSSEN H. A. CAPELL & J. F. MACKENZIE 5 Protective action of diosmectite treatment on Short report: time course of clinical response digestive disturbances induced by intestinal with fluconazole for Candida oesophagitis in anaphylaxis in the guinea-pig. V. THEODOROU, patients with AIDS. C. M. WILCOX J. FIORAMONTI, M. T. DROY-LEFAIX, O. PLIQUE Short report: evaluation of Helicobacter pylori & L. BUENO eradication with bismuth sucralfate. Anaphylactic colonic hypersecretion in cow’s M. H. E. REIJERS, L. A.N OACH milk sensitized guinea-pigs depends upon release & G. N. J. TYTGAT of Interleukin-1, prostaglandins and mast cell Short report: interferon-« decreases degranulation. V. THEODOROU, J. FIORAMONTI, '4C_aminopyrine breath test values in patients J. L. JUNIEN & L. BUENO with chronic hepatitis. C. Y.H ORSMANS, Comparison of lansoprazole with omeprazole on R. BRENARD & A. P. GEUBEL 24-hour intragastric pH, acid secretion and Erratum serum gastrin in healthy volunteers. S. BRULEY DES VARANNES, P. LEVY, S. LARTIGUE, F. DELLATOLAS, M. LEMAIRE & J. P. GALMICHE 5 Effect of ursodeoxycholic acid on in vivo and in vitro toxic liver injury in rats. V. SIMKO & S. MICHAEL Contents VOLUME 8 NUMBER 4 AUGUST Review article: treatments that impact A dose-ranging study of ranitidine and its effect favourably upon the eradication of Helicobacter on intragastric and intra-oesophageal acidity in pylori and ulcer recurrence. G. N. J. TYTGAT subjects with gastro-oesophageal reflux disease. Review article: Helicobacter pylori A. B. R. THOMSON, L. BABIUK, P. KIRDEIKIS, eradication—understandable caution but no L. ZUK, B. MARRIAGE & K. BOWES excuse for inertia. J. G. PENSTON Clarithromycin—amoxycillin therapy for Review article: orthograde gut lavage for Helicobacter pylori infection. colonoscopy. M. A. BERRY & J. A. DIPALMA M. T. AL-ASSI, R. M. GENTA, T. J. KARTTUNEN A dose-response study of orally administered & D. Y. GRAHAM torsemide in patients with ascites due to The outcome of peptic ulcer haemorrhage in cirrhosis. J. J. APPLEFELD, R. J. KASMER, relation to consumption of nonsteroidal anti- L. J. HAK, G. E. DUKES, D. P. WERMELING & inflammatory drugs or aspirin. C. P.C HOUDARI, C. J. McCLAIN R. A. ELTON & K. R. PALMER Alosetron does not affect the visceral perception Inhibition of 5-hydroxytryptamine re-uptake of gastric distension in healthy subjects. impairs human gall-bladder emptying. F. ZERBIB, S. BRULEY DES VARANNES, D. A. GORAKD, J. C. HEALY, L. J. D. R. C. ORIOLA, J. McDONALD, J. P. ISAL & O'DONNELL & M. J. G. FARTHING J. P. GALMICHE Steroid treatment in active Crohn’s disease: a Antidepressant therapy in 138 patients with comparison between two regimens of different irritable bowel syndrome: a five-year clinical duration. C. BRIGNOLA, G. DE SIMONE, experience. R. E. CLOUSE, P. J. LUSTMAN, C. BELLOLI, P. IANNONE, A. BELLUZZI, R. A. GEISMAN & D. H. ALPERS P. GIONCHETTI, M. CAMPIERI & L. BARBARA ’ Ulceration, fibrosis and diaphragm-like lesions in Omeprazole, bismuth and clarithromycin in the the caecum of rats treated with indomethacin. sequential treatment of Helicobacter pylori A. ANTHONY, A. P. DHILLON, R. SIM, infection. M. NERI, D. SUSI, F. LATERZA, G. NYGARD, R. E. POUNDER & A. J. WAKEFIELD P. DI IORIO, G. SECCIA, A. MEZZETTI & The effect of tripotassium dicitrato bismuthate F. CUCCURULLO on the rat stomach. H. L. WALDUM, Letter to the Editors. G. QVIGSTAD, R. MARVIK, E. BRENNA, U. SYVERSEN & A. K. SANDVIK Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat. R. FABIA, A. Ar’RAJAB, R. WILLEN, R. BRATTSAND, M. ERLANSSON & E. SVENSJO Contents vii VOLUME 8 NUMBER 5 OCTOBER Review article: gastroduodenal bicarbonate A selective NK-2 antagonist blocks the increase secretion. D. L. HOGAN, M. A. AINSWORTH & of canine colonic tone and ileal contractions J. I. ISENBERG induced by the NK-2 selective receptor agonist, Scintigraphic assessment of the intragastric [fAla8] neurokinin A-(4-10). G. BASILISCO & distribution and gastric emptying of an S. F. PHILLIPS encapsulated drug: the effect of feeding and of a Bioavailability of single and multiple doses of a proton pump inhibitor. J. C.A THERTON, new oral formulation of 5-ASA in patients with N. WASHINGTON, M. A. BRACEWELL, inflammatory bowel disease and healthy L. J. SUTTON, J. L. GREAVES, A. C. PERKINS, volunteers. P. GIONCHETTI, M. CAMPIERI, C. J. HAWKEY & R. C. SPILLER A. BELLUZZI, $. BOSCHI, C. BRIGNOLA, Amoxycillin capsules with omeprazole for the M. MIGLIOLI & L. BARBARA eradication of Helicobacter pylori. Assessment of Long term treatment with omeprazole 20 mg the importance of antibiotic dose timing in three days a week or 10 mg daily in the relation to meals. J. C.A THERTON, N. HUDSON, prevention of duodenal ulcer relapse. G. E. KIRK, C. K. HAWKEY & R. C. SPILLER G. BIANCHI PORRO , R. CORINALDESI, Meta-analysis of smooth muscle relaxants in the M. LAZZARONI, L. BARBARA, L. CAPURSO, treatment of irritable bowel syndrome. P. PAOLUZI, A. MANGIAMELI, F. SABBATINI, T. POYNARD, S. NAVEAU, B. MORY M. FRANCESCHI & E. BOLLING & J. C.C HAPUT Effects of pantoprazole on endocrine function in Bran supplementation in the treatment of healthy male volunteers. H.G . DAMMANN, irritable bowel syndrome. J. SNOOK Tu. BETHKE, F. BURKHARDT, N. WOLF, & H. A. SHEPHERD H. KHALIL & R. LUEHMANN 5 Basal serum gastrin concentrations before and Studies of water movement across the gut using after eradication of Helicobacter pylori infection oral rehydration solutions in a rat perfusion measured by sequence specific radioimmuno- model. G. V. PILLAI, M. J. BRUETON, assays. E. M. WITTEMAN, M. L. VERHULST, D. BURSTON & B. K. SANDHU R. W. dE KONING, W. P. M. HOPMAN Comparative assessment of phenolpthalein and & J. B. M. J. JANSEN glucuronide: is phenolphthalein glucuronide a Low dose aspirin: selective inhibition of rectal better laxative? B. S. ANAND, E. TORRES, dialysis thromboxane B, in healthy volunteers. A. OPERKUN & D. Y. GRAHAM A. T. COLE, B. FILIPOWICZ, P. HYMAN- TAYLOR & C. J. HAWKEY viii Contents VOLUME 8 NUMBER 6 DECEMBER 563 Review article: practical management of the Polymeric nutrition as the primary therapy in short bowel: J. E. LENNARD-JONES children with small bowel Crohn’s disease: R. M. 579 Review artcle: infective complications of BEATTIE, E. J. SCHIFFRIN, A. DONNET- therapeutic gastric acid inhibition: A. J. LARNEK HUGHES, A. C. HUGGET, P. DOMIZIO, & M. I. R. HAMILTON T. T. MACDONALD & J. A. WALKER-SMITH Oral budesonide for treatment of autoimmune Pharmacokinetics and retrograde colonic spread chronic active hepatitis: A. DANIELSSON of budesonide enemas in patients with distal & H. PRYTZ ulcerative colitis: M. NYMAN-PANTELIDIS, Budesonide enema in active haemorrhagic A. NILSSON, Z. G-WAGNER & O. BORGA proctitis—a controlled trial against Budesonide versus prednisolone retention hydrocortisone foam enema: S. TARPILA, enemas in active distal ulcerative colitis: U. TURUNEN, K. SEPPALA, S. AUKEE, R. LOFBERG, 0. @STERGAARD THOMSEN, P. PIKKARAINEN, I. ELOMAAS, E. LANGHOLZ, R. SCHIOLER, A. DANIELSSON, A-L. KARVONEN, I. KAARIAINEN, O. SUHR, H. GRAFENER, L. PAHLMAN, P. SIPPONEN, E. TOIVANEN, B. HEIKIUS, P. MATZEN, J. F. MOLLERR-PETERSON, S. NIEMELA, H. NURMI, H. TUNTURI- L. HALVORSEN, N. HOVDENAK, R. WILLEN, HIHNALA, W. R. BURNHAM, R. E. COWAN, T. PERSSON & C. SEIDEGARD K. R. HINE, T. PERSSON & L. SALDE The effects of levosulpiride on gastric and gall- Dexamethasone promotes ulcer plugging in bladder emptying in functional dyspepsia: experimental enteritis: A.A NTHONY, V. ARIENTI, G. R. CORAZZA, M. SORGE, A. P. DHILLON, R. SIM, R. E. POUNDER L. BORIANI, F. UGENTI, F. BIAGI, G. MACONI, & A. J. WAKEFIELD S. SOTTILI, D. H. VAN THIEL & G. GASBARRINI Compaarison of a high lipase pancreatic enzyme Rolling review: the treatment of major extract with a regular pancreatin preparation in complications in cirrhosis: J. BOSCH, J. BRUIX, adult cystic fibrosis patients: K. H. GAN, A. MAS, M. NAVASA & J. RODES H. G. M. HEIJERMAN, W. P. GEUS, W. BAKKER Letters to the Editors & C. B. H. W. LAMERS Index