Table Of Content

AGE AND AGEING VOLUME 22 1993 EDITOR J. GRIMLEY EVANS Published by Oxford University Press O O Z R F w W Z e W CONTENTS Commentary: Treatment of Elderly Hypertensives: Some Questions Remain Unanswered T. A. Farnsworth and D. Heseltine Effect of Exercise on Cardiovascular Ageing F. W. Kasch,¥ . L. Boyer, S. P. van Camp, L. S. Verity and #. P. Wallace A Controlled Trial of Exercise by Residents of Old People’s Homes M. E. T. McMurdo and L. Rennie Survey of 160 Centenarians in Shanghai Zhi-Xue Zheng, Zan-Shun Wang, Hai-Min Zhu, Fian- Ying Yang, Hai- Ying Peng, Li-Xian Wang, Jian Li, Xiong-Wan Fiang and Yue-Fei Yu Quantification of the Cardinal Signs of Parkinsonism and of Associated Disability in Spouses of Sufferers C. Kirollos, C. ¥.A . O’ Neill, R. #. Dobbs, A. Charlett, S. G. Bowes, C. Weller, A. G. Purkiss, W. B. Hunt and S. M. Dobbs Is This Walk Normal? R. }. Dobbs, A. Charlett, S. G. Bowes, C. J. A. O’ Neill, C. Weller, #7.H ughes and S. M. Dobbs Percutaneous Transluminal Coronary Angioplasty for Post-infarction Angina in Elderly Patients A. Iniguez, C. Macaya, F. Alfonso, R. Hernandez, 7. Goicolea, ¥.M . Ribera and P. Zarco The Association of Age with Gastric Emptying N. Gainsborough, V. L. Maskrey, M. L. Nelson,} . Keating, R. A. Sherwood, S. H. D. Jackson and C. G. Swift Is Caffeine a Factor in Subjective Insomnia of Elderly People? R. Curless,J .M . French, O. F. W. James and.H. A. Wynne The Incidence of Neglect Phenomena and Related Disorders in Patients with an Acute Right or Left Hemisphere Stroke S. P. Stone, P. W. Halligan and R. }. Greenwood Outcome of an Integrated Approach to the Investigation of Dizziness, Falls and Syncope in Elderly Patients Referred to a ‘Syncope’ Clinic S. McIntosh, D. Da Costa and R. A. Kenny Falling and Perimenopausal Women D. F. Torgerson, M. F. Garton and D. M. Reid Review: Abuse of Elderly People in the Domestic Setting: A UK Perspective C. McCreadie and A. Tinker Commentary: Metabolic Switches in Ageing J. Grimley Evans The Influence of Urinary Incontinence on the Quality of Life of Elderly Women A. Grimby, I. Milsom, U. Molander, I. Wiklund and P. Ekelund ill CONTENTS The Energetic Cost of Some Daily Activities: A Comparison in a Young and Old Population 3. P. Didier, F. Mourey, L. Brondel, I. Marcer, C. Milan, 7. M. Casillas, B. Verges and }. K. D. Winsland Hospital Admissions for Asthma in Finland during 1972-86 of Adults Aged 65 Years and Over T. Tuuponen, T. Keistinen and S.-L. Kiveld Assessment of Nutrient Intake and Associated Factors in an Indian Elderly Population V. S. Natarajan, S. Ravindran, Sivashanmugam, Thyagarajan, K. Kailash, B. Krishnaswamy, B. Suresh and P. Prabhu oPtOPliAp @t e) Expressed Wish to Die and Mortality in Older People: A Community Replication M. E. Dewey, I. A. Davidson and J. R. M. Copeland Water Balance in Elderly People: Is There a Deficiency of Vasopressin? C. M. Faull, C. Holmes and P. H. Baylis Is There a Right Age for Case Finding in Elderly People? N. J. Vetter, P. A. Lewis and L. Llewellyn Subtypes of Overactive Bladder in Old Age G. Geirsson, M. Fall and S. Lindstrém Resting Energy Expenditure in Relation to Energy Intake in Patients with Alzheimer’s Disease, Multi-infarct Dementia and in Control Women L. Niskanen, M. Piirainen, M. Koljonen and M. Uusitupa Review: Alzheimer’s Disease and Environmental Aluminium Sir Richard Doll Commentary: Standardized Functional Assessment Scales for Elderly Patients H. Rodgers, R. Curless and O. F. W. James Guillain-Barré Syndrome in Oxfordshire: Clinical Features in Relation to Age S. J. Winner and }. Grimley Evans The Barthel ADL Index: Scoring by the Physician from Patient Interview is not Reliable A. H. Ranhoff and K. Laake The Association between Mental, Social and Physical Activity and Cognitive Performance in Young and Old Subjects H. Christensen and A. Mackinnon Assessment in Severe Dementia: The Guy’s Advanced Dementia Schedule T. Ward, B. Dawe, A. Procter, E. Murphy and J. Weinman Factors Associated with Decline in Function, Institutionalization and Mortality of Elderly People C. Jagger, N. A. Spiers and M. Clarke Relationships between Parathyroid Hormone, 25-Hydroxyvitamin D, and Bone Mineral Density in Elderly Men S. Murphy, K-T. Khaw, A. Prentice and J. E. Compston Attitudes of Relatives to Autopsies of Elderly Patients S. A. Solomon and K. H. R. Adams CONTENTS Autopsy: Consent, Completion and Communication in Alzheimer’s Disease Research E. M-F. O. King, A. Smith and K. A. Jobst Helicobacter pylori Infection in Elderly People: Correlation between Histology and Serology A. F. Safe, B. Warren, A. Corfield, C. A. McNulty, B. Watson, R. A. Mountford and A. Read Bacterial Surveillance Cultures in a Geriatric Ward W. Michielsen, D. Vandevondele, G. Verschraegen, G. Claeys and M. Afschrift Lung Cancer in Elderly Patients: The Role of Induced Sputum Production to obtain a Cytological Diagnosis C.I.A. Jack, J.D . H. Sheard, B. Lippitt, A. Fromholtz, C. C. Evans and C.R. K. Hind Commentary: Ageing as a Global Issue K. Steel and S. Maggi Cranial Computed Tomography of Elderly Patients: An Evaluation of its Use in Acute Neurological Presentations G. Brown, M. Warren,# . E. Williams, E. 7.A dam and 7. A. Coles A Study of Nutritional Deficits of Long-stay Geriatric Patients P. S. Lipski, A. Torrance, P. ¥. Kelly and O. F. W. Fames Role of Serology in Monitoring Treatment for Helicobacter pylori Infection in Elderly Patients A. F. Safe, B. Warren, A. Corfield, C. A.M cNulty, B. Watson, R. A. Mountford and A. Read Delay in Diagnosis of Colorectal Cancer in Elderly Patients M. Kemppainen, I. Raihad, T. Rajala and L. Sourander Four-compartment Model of Body Composition of Normal Elderly Women H. Rico, M. Revilla, E. R. Hernandez, ?. M. Gonzalez-Riola and L. F. Villa Arterial Oxygen Saturation and Posture in Acute Stroke J. Elizabeth, J. Singarayar, }. Ellul, D. Barer and M. Lye Seasonal Variation of Serum Lipids in an Elderly Population P. R. Woodhouse, K-T. Khaw and M. Plummer A Pilot Leg Ulcer Clinic in a Geriatric Day Hospital M. R. Bliss and M. Schofield Epidemiology of Proximal Femoral Fracture in Gran Canaria (Canary Islands) M. Sosa, M. C. Segarra, D. Hernandez, A. Gonzalez, ¥. M. Limiriana and P. Betancor The Association of Age with the Presentation and Outcome of Tuberculosis: a Five-year Survey C. Teale, ¥.M . Goldman and S. B. Pearson Are Elderly People at Risk of Falling taught how to get up again? J. M. Simpson and S. Salkin Hypothesis: Healthy Active Life Expectancy (HALE) as an Index of Effectiveness of Health and Social Services for Elderly People ¥. Grimley Evans CONTENTS Review: Silent Exertional Myocardial Ischaemia and Perception of Angina in Elderly People G. B. Ambepitiya, E. N. Iyengar and M. E. Roberts Commentary: Who Should Have a PEG? S. K. Raha and K. W. Woodhouse An Evaluation of the Efficacy and Safety of Tetrahydroaminoacridine (THA) without Lecithin in the Treatment of Alzheimer’s Disease G. K. Wilcock, D. ¥.S urmon, M. Scott, M. Boyle, K. Mulligan, K. A. Neubauer, D. O’ Neill and V. H. Royston Post-operative Electrolyte Imbalance: Its Incidence and Prognostic Implications for ONAZmMAZOOElde rly Orthopaedic Patients R. Antonelli Incalzi, A.G emma, O. Capparella, L. Terranova, C. Sanguinetti and P. U. Carbonin The Association of Age with Plasma Arginine Vasopressin and Plasma Osmolality J. Duggan, S. Kilfeather, S. L. Lightman and K. O’ Malley The Scope of Neurosurgery for Elderly People R. S. Maurice-Williams and N. Kitchen Hypertensive Old People in Edinburgh (HOPE) Study: Electrocardiographic Changes after Captopril or Bendrofluazide Treatment J. M. Starr and L. 7. Whalley Detecting Depression in Elderly Medically Ill Patients: The Use of the Geriatric Depression Scale compared with Medical and Nursing Observations R. Jackson and B. Baldwin The Association of Age and Frailty with the Pharmacokinetics and Pharmacodynamics of Metoclopramide H. A. Wynne, C. Yelland, L. H. Cope, A. Boddy, K. W. Woodhouse and D. N. Bateman The Social Consequences of Surgical Complications for Patients with Proximal Femoral Fractures H. D. H. Eastwood Prevalence and Change of Cardiovascular Risk Factors among Men born 1900-19: The Finnish Cohorts of the Seven Countries Study A. Nissinen, M. Tervahauta, 7. Pekkanen, P. Kivinen,J . Stengard, E. Kaarsalo, S-L. Kivela, S. Vaisdnen, 7. T. Salonen and }. Tuomilehto Health Care for Elderly People in Developing Countries: A Case Study of Thailand S. Fitapunkul, S. Bunnag and S. Ebrahim Review: Trials of Withdrawal of Diuretics JF. W. de Fonge, J.A . Knottnerus, W. M. van Zutphen and G. A. de Bruijne Commentary: Geriatricians and Quality Assurance I. Philp and K. Rockwood Repeatability and Relationship between Arterialized Catecholamines and Blood Pressure in Elderly Subjects J. F. Potter, M. D. Fotherby and I. A. Macdonald CONTENTS Association of Age with the Efficacy and Safety of Ranitidine and Cimetidine in Acute Duodenal Ulcer Disease J. S. Dixon, J.G . Mills, R. S. B. Ehsanullah and J. R. Wood Use of the Extended ADL Scale with Stroke Patients J. R. F. Gladman, N. B. Lincoln and S. A. Adams Dying when You’re Old A. Cartwright Bloodstream Infections in Patients Older than Eighty Years L. Letbovici, S. D. Pitlik, H. Konisberger and M. Drucker Quantification of Proteinuria: A Re-evaluation of the Protein/Creatinine Ratio for Elderly Subjects S.C. M. Mitchell, T. A. Sheldon and A. B. Shaw ‘Toxic Epidermal Necrolysis (Lyell Syndrome) in 77 Elderly Patients S. Bastuji-Garin, M. Zahedi, #.-C. Guiliaume and J.-C. Roujeau Four Instrumental Activities of Daily Living Score as a Predictor of One-Year Incident Dementia P. Barberger-Gaiea}u.-,F . Dartigues and L. Letenneur Review: Patient-related Predictors of Cardiopulmonary Resuscitation of Hospitalized Patients P. L. J. Dautzenberg, T. C. J}. Broekman, C. Hooyer, R. S. Schonwetter and S.A. Duursma Letters to the Editor ©, 154, 230, 389, 476 Book Reviews 2, 155, 233, 308, 394, 478 Books Received 78, 160, 236, 312, 400, 484 MECHANISMS OF HOMOEOSTASIS IN AGEING A symposium of the Sandoz Foundation for Gerontological Research Supplement No 1, 1993 (see Issue No 1) Guest Editor: HANNES B. STAHELIN Introduction The Sandoz Foundation for Gerontological Research Hannes B. Stahelin Neuroendocrine Regulation Toward understanding of the molecular basis of loss of neuronal plasticity in ageing N. Mori Thymus-pituitary interactions during ageing Rodolfo G. Goya, Maria G. Castro, Peter W. Saphier, Yolanda E. Sosa and Philip 7. Lowry CONTENTS Disturbed fluid and eiectrolyte homoeostasis following dehydration in elderly people P. A. Phillips, C. I. Johnston and L. Gray Genetic Mechanisms Biological significance of DNA methylation in the ageing process Tetsuya Ono, Yoshihiko Uehara, Akthiro Kurashita, Riichi Tawa and Hiromu Sakurai Studies on DNA repair defects in degenerative brain disease Michael E. T. I. Boerrigter and Jan Vijg Concluding remarks The importance of basic research in gerontology OePBhP@1te)peAe Robert N. Butler giaan eld ‘aa