Adverse Effects of Herbal Drugs PDF
Preview Adverse Effects of Herbal Drugs
Adverse Effects of Herbal Drugs Volume 3 Editors P.A.G.M. De Smet (Managing Editor) K. Keller R. Hansel R. F. Chandler Springer Berlin Heidelberg New York Barcelona Budapest Hong Kong London Milan Paris Santa Clara Singapore Tokyo Adverse Effects of Herbal Drugs 3 Edited by P. AG.M. De Smet (Managing Editor) K. Keller R. Hansel R. F. Chandler Contributors G. Abel R. Bos LH.Bowen R.F.Chandler D.Corrigan I. 1. Cubbin P.A.G.M. De Smet N. Pras U.c. Scheffer T.A.Van Beek W. Van Uden H.1. Woerdenbag In collaboration with the Pharmaceuticals Programme of the World Health Organization, Regional Office for Europe Springer Dr. PETER A.G.M. DE SMET Royal Dutch Association for the Advancement of Pharmacy Alexanderstraat 11, 2514 JL The Hague The Netherlands Dr. KONSTANTIN KELLER Bundesinstitut fOr Arzneimittel und Medizinprodukte SeestraBe 10, 13353 Berlin Germany Prof. Dr. RUDOLF HANSEL WestpreuBenstraBe 71,81927 Miinchen Germany Prof. Dr. R. FRANK CHANDLER College of Pharmacy, Dalhousie University, Halifax B3H3J5 Canada ISSN 0942-2242 ISBN-13: 978-3-540-60181-4 e-ISBN-13: 978-3-642-60367-9 DOl: 10.1007/978-3-642-60367-9 Library of Congress Cataloging-in-Publication Data 92-219771 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadca- sting, reproduction on microfilm or in other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Sprlnger-Verlag. Violations are liable for prosecution under the German Copyright Law. Although great effort has been made to provide the reader with reliable data, the contributors, editors, and publisher cannot assume responsibility for the Validity of all information in this book or for the consequences of its use. © Springer-Verlag Berlin Heidelberg 1997 Reprint of the original edition 1997 The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. SPIN: 10500557 13/3133-5 4 3 2 1 0 - Printed on acid-free paper Pour Valerie qui m'e nrubanne de nouveau Preface This third contribution to our series has the same approach as the previous two volumes. The book opens with a general introductory chapter (this time on herbal postmarketing surveillance), which is fol- lowed by eighteen comprehensive monographs about specific medici- nal herbs and important plant constituents. The herbs and constituents have been selected for several reasons, such as a prominent place in phytotherapy (e.g. Valeriana species), clinical expectations about therapeutic potential (e.g. Tripterygium species), and recent concern about a serious adverse reaction (e.g. Teucrium chamaedrys). Just as before, the result is a blend of new and old information. December 1995 THE EDITORS Contents An Introduction to Herbal Pharmacovigilance .................. . P.A.G.M. DE SMET Artemisia Cina .......................................... 15 H. J. WOERDENBAG, W. VAN UDEN and N. PRAS Aspalathus Linearis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 P.A.G.M. DE SMET Citrullus Colocynthis ..................................... 29 P.A.G.M. DE SMET Fucus Vesiculosus and Allied Brown Algae .................... 37 I. H. BOWEN and I. J. CUBBIN Ginkgo Biloba ........................................... 51 H. J. WOERDENBAG and LA. VAN BEEK Glycyrrhiza Glabra . ...................................... 67 R. F. CHANDLER Linum Usitatissimum . ..................................... 89 H. J. WOERDENBAG, W. VAN UDEN and N. PRAS Phoradendron Flavescens . ................................. 99 P.A.G.M. DE SMET Safrole - General Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 105 G.ABEL Safrole - Sassafras Albidum ............................... 123 G.ABEL X Contents Spirulina Species ..... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 129 P.A.G.M. DE SMET Teucrium Chamaedrys . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 137 P.A.G.M. DE SMET Tripterygium Species . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 145 P.A.G.M. DE SMET Valeriana Species ....................................... 165 R. Bos, H. J. WOERDENBAG, P.A.G.M. DE SMET and J. J. C. SCHEFFER Y ohimbe Alkaloids - General Discussion. . . . . . . . . . . . . . . . . . .. 181 P.A.G.M. DE SMET Yohimbe Alkaloids - Cdrynanthe Species ................... 207 P.A.G.M. DE SMET Yohimbe Alkaloids - Pausinystalia Species. . . . . . . . . . . . . . . . .. 211 P.A.G.M. DE SMET Zingiber Officinale ...................................... 215 D. CoRRIGAN Notes Added in Proof .................................... 229 P.A.G.M. DE SMET Subject Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 24 I Contributors Dr. GUDRUN ABEL Plan tamed Arzneimittel GmbH, KerschensteinerstraBe 11-15, Postfach 57, 92318 NeumarktlOpf., Germany Mr. REINBos Department of Pharmaceutical Biology, University Centre for Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 A V Groningen, The Netherlands Dr. IAN BOWEN School of Health Sciences, University of Sunderland, Langham Tower, Ryhope Road, Sunderland SR2 7EE United Kingdom Prof. Dr. R. FRANK CHANDLER College of Pharmacy, Dalhousie University, Halifax B3H 3J5, Canada Dr. DESMOND CORRIGAN Department of Pharmacognosy, School of Pharmacy, Trinity College, 18 Shrewsbury Road, Dublin 4 Ireland Mr. IAN CUBBIN School of Health Sciences, University of Sunderland, Langham Tower, Ryhope Road, Sunderland SR2 7EE United Kingdom XII Contributors Dr. PETER A.G.M. DE SMET Royal Dutch Association for the Advancement of Pharmacy, Alexanderstraat 11, 2514 JL The Hague The Netherlands Dr. NIESKO PRAS Department of Pharmaceutical Biology, University Centre for Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 A V Groningen, The Netherlands Prof. Dr. J. C. C. SCHEFFER Di vision of Pharmacognosy, LACDR, Leiden University, Gorlaeus Laboratories, POBox 9502, 2300 RA Leiden, The Netherlands Dr. TERIS A. V AN BEEK Phytochemical Section, Department of Organic Chemistry, Wageningen Agricultural University, Dreijenplein 8, 6703 HB Wageningen, The Netherlands Dr. WIM VAN UDEN Department of Pharmaceutical Biology, University Centre for Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 A V Groningen, The Netherlands Dr. HERMAN J. WOERDENBAG Department of Pharmaceutical Biology, University Centre for Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 A V Groningen The Netherlands
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