Adverse Effects of Herbal Drugs 2 PDF
Preview Adverse Effects of Herbal Drugs 2
Adverse Effects of Herbal Drugs Volume 2 Editors P.A.G.M. De Smet (Managing Editor) K. Keller R. Hansel R. F. Chandler Adverse Effects of Herbal Drugs 2 Edited by P.A.G.M. De Smet (Managing Editor) K. Keller R. Hansel R. F. Chandler Contributors I.H. Bowen D. Corrigan I.J. Cubbin P.A.G.M. De Smet R. Hansel U. Sonnenborn J. Westendorf H. Winterhoff H. J. Woerdenbag In collaboration with the Pharmaceuticals Programme of the World Health Organization, Regional Office for Europe Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona Budapest Dr. PETER A.G.M. DE SMET Drug Information Center Royal Dutch Association for the Advancement of Pharmacy Alexanderstraat 11, 2514 JL The Hague The Netherlands Dr. KONSTANTIN KELLER Institut flir Arzneimittel des Bundesgesundheitsamtes SeestraBe 10, 13353 Berlin Germany Prof. Dr. RUDOLF HANSEL WestpreuBenstraBe 71,81927 Mtinchen Germany Prof. Dr. R. FRANK CHANDLER College of Pharmacy, Dalhousie University, Halifax B3H 3J5 Canada ISSN 0942-2242 ISBN-13: 978-3-540-55800-2 e-ISBN-13: 978-3-642-48906-8 DOl: 10.1007/978-3-642-48906-8 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustration- s, recitation, broadcasting, reproduction on microfilm or in other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provi- sions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. Although great effort has been made to provide the reader with reliable data, the contribu- tors, editors, and publisher cannot assume responsibility for the validity of all information in this book or for the consequences of its use. © Springer-Verlag Berlin Heidelberg 1993 The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Typesetting: Best-Set Typesetter Ltd., Hong Kong 13/3145-5 4 3 2 I 0 - Printed on acid-free paper To Isolde A Blue Butterfly in the Delta Preface This second volume has the same purpose and set-up as the first one. There is a general introductory chapter on the legislation of herbal remedies in different countries, which is followed by twenty- six plant-oriented monographs. Some of these plants have been se- lected because of recent concerns about their adverse reaction po- tential (e. g. Scutellaria species), whereas others have been included because they still have a prominent place in phytotherapy (e. g. Hedera helix). The result is a blend of old and new data, which is precisely what one may expect from a comprehensive coverage. April 1993 THE EDITORS Contents Legislatory Outlook on the Safety of Herbal Remedies. . . . . . . 1 P.A.G.M. De Smet Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 European Economic Community. . . . . . . . . . . . . . . . . . . . 1 Germany....................................... 3 France. . . . . . .. . .. . . . . . . . . ... . . . . . . . . .... . .. . . .. 6 Belgium......................... ............... 7 United Kingdom:. . . .. . ... ... . . .. . . . . ..... .. . . ... 7 United States. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Australia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Sweden........................................ 15 Individual Herbal Drugs. . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Abies, Picea and Pinus Species. . . .. . . . . . . . . . .. . ... . . . ... 91 D. CORRIGAN Anthranoid Derivatives - General Discussion. . . . . . . . . . . .. 105 J. WESTENDORF Anthranoid Derivatives - Aloe Species. . . . . . . . . . . . . . . . .. 119 J. WESTENDORF Anthranoid Derivatives - Cassia Species. . . . . . . . . . . . . . . .. 125 J. WESTENDORF Anthranoid Derivatives - Rhamnus Species. . . . . . . . . . . . .. 129 J. WESTENDORF Anthranoid Derivatives - Rheum Species. . . . . . . . . . . . . . .. 133 J. WESTENDORF Anthranoid Derivatives - Rubia Species. . . . . . . . . . . . . . . .. 137 J. WESTENDORF X Contents Arctium Species . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 141 P.A.G.M. DE SMET Borago Officinalis .................................... 147 P.A.G.M. DE SMET Caulophyllum Thalictroides. . . . . . . . . . . . . . . . . . . . . . . . . . . .. 153 P.A.G.M. DE SMET Eleutherococcus Senticosus ............................. 159 U.SONNENBORN,R.HANSEL Eupatorium Species . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171 H.J. WOERDENBAG Gossypol ............................................ 195 H.J. WOERDENBAG Hedera Helix. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209 P.A.G.M. DE SMET Juniperus Species ..................................... 217 D.CORRIGAN Larrea Tridentata . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231 P.A.G.M. DE SMET Lithospermum Species ................................. 241 H. WINTERHOFF Lycopus Species ...................................... 245 H. WINTERHOFF Phytolacca Americana ................................ 253 P.A.G.M. DE SMET Podophyllum Species .................................. 263 I.H. BOWEN, I.J. CUBBIN Polygala Species ...................................... 275 P.A.G.M. DE SMET Quillaja Saponaria .................................... 283 P.A.G.M. DE SMET Contents XI Scutellaria Species. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 289 P.A.G.M. DE SMET Taraxacum Officillale . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 297 P.A.G.M. DE SMET Tilia Species . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 303 P.A.G.M. DE SMET Vaccinium myrtillus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 307 P.A.G.M. DE SMET Notes Added in Proof ................................. 315 P.A.G.M. DE SMET Subject Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 319 Contributors Dr. IAN BOWEN School of Health Sciences, Sunderland University of Langharn Tower, Ryhope Road, Sunderland SR2 7EE United Kingdom Dr. DESMOND CORRIGAN Department of Pharmacognosy, School of Pharmacy, Trinity College, 18 Shrewsbury Road, Dublin 4 Ireland Mr. IAN J. CUB BIN School of Health Sciences, SunderlandUniversity of Langham Tower, Ryhope Road, Sunderland SR2 7EE United Kingdom Dr. PETER A.G.M. DE SMET Drug Information Center, Royal Dutch Association for the Advancement of Pharmacy, Alexanderstraat 11, 2514 JL The Hague The Netherlands Prof. Dr. RUDOLF HANSEL WestpreuBenstraBe 71,81927 Miinchen Germany Dr. ULRICH SONNENBORN Fa. Dr. Poehlmann & Co, LoerfelderstraBe 20, 58313 Herdecke Germany XIV Contributors Prof. Dr. JOHANNES WESTENDORF Institut fiir Pharmakologie, Universitat Hamburg, Grindelallee 117, 20146 Hamburg Germany Dr. HILKEWINTERHOFF Institut fUr Pharmakologie und Toxikologie, WestHilische Wilhelms-Universitat Munster, DomagkstraBe 12,48149 Munster Germany Dr. HERMAN J. WOERDENBAG Department of Pharmacognosy, University Centre for Pharmacy, University of Groningen, Antonius Deusinglaan 2, 9713 AW Groningen The Netherlands
The list of books you might like
