Advances in Haemapheresis: Proceedings of the Third International Congress of the World Apheresis Association. April 9–12,1990, Amsterdam, The Netherlands

279 Pages·1991·12.089 MB·English

by  H. J. Gurland (auth.), C. Th. Smit Sibinga, L. Kater (eds.)

ADVANCES IN HAEMAPHERESIS
DEVELOPMENTS IN HEMATOLOGY AND IMMUNOLOGY
Volume 25
The titles published in this series are listed at the end o/this volume.
Advances in
haemapheresis
Proceedings of the Third International Congress of the World Apheresis Association.
April 9-12, 1990, Amsterdam, The Netherlands
edited by
C.Th. SMIT SIBINGA
Red Cross Blood Bank Groningen-Drenthe, The Netherlands
and
L.KATER
University Hospital Utrecht, The Netherlands
KLUWER ACADEMIC PUBLISHERS
DORDRECHT / BOSTON / LONDON
Library of Congress Cataloging-in-Publication Data
World Apheresis Assoclation. International Congress (3rd 1990
Amsterdam, Netherlands)
Advances ln haemapheresls proceedings of the 3rd International
Congress of the World Apheresis Association. April 9-12. 1990.
Amsterdam. NL I edited by C.Th. Smit Sibinga and L. Kater.
p. cm. -- CDeve I opments in hemato logy and i mmuno logy ; v. 25)
Inc I udes index.
ISBN 0-7923-1312-7 (hb alk. paper)
1. Hemapheresis--Congresses. I. Smit Sibinga. C. Th. II. Kater,
Louis. III. Title. IV. Serles: Developments in hematology and
i romu~c logy ; 25.
[DNLM: 1. Hematopoietic Stem eel ls--transplantatlon--congresses.
2. Neoplasms--therapy--congresses. 3. Nervous System Diseases-
-therapy--congresses. 4. Plasmapheresis--congresses. W1 DE997VZK
v. 25 / WH 460 W927ab 19901
RM173.W67 1990
615' .39--dc20
DNLM/[')LC
for Library of Congress 91-20797
CIP
ISBN 0-7923-1312-7
Published by Kluwer Academic Publishers,
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Opening ceremony of the 3rd International Congress of the Wodd Apheresis
Association.
1 to r: Prof. Gerard Rifle (1st WA A president), Dr. Cees Th. Smit Sibinga
(congress president), Dr. Annette Bussel (assistant secretary-general) and Prof.
Yukihiko Nose (secretary-general)
Acknowledgement
This publication has been made possible through the support of Fresenius, which is
greatfully acknowledged
VII
CONTENTS
Moderators and speakers ........................................................................... XI
Foreword ................................................................................................... XV
Apheresis, a new-old treatment modality
I. Djerassi ................................................................................................ XVII
I. Plasmapheresis: Centrifugation versus filtration
Introductory remarks to the plenary symposium:
Centrifugation versus filtration
H.J. Gurland ................................................................................................... 1
The advantages of centrifugation in therapeutic plasmapheresis
P. Konstantin ................................................................................................. 5
High performance systems for membrane plasmapheresis
M.Y. Jaffrin ................................................................................................. 13
Two year clinical experience using a rotating filter for
therapeutic plasma exchange
A.A. Kaplan ................................................................................................. 21
Donor plasmapheresis technology
R.R. Stromberg ............................................................................................ 29
II. Plasmapheresis in neurology
Plasma exchange in peripheral neuropathy
R.A.C. Hughes ............................................................................................. 39
Plasma exchange and Guillian-Barre syndrome
J.C. Raphael ................................................................................................. 51
Are immunoglobulins superior to plasma exchange in the
Guillain -Barre syndrome?
F.G.A. van der Meche ................................................................................ 59
VIII
Plasmapheresis in neurological disorder
B.O. Khatri ................................................................................................... 69
Therapeutic strategies in multiple sclerosis: The value of
plasma exchange
C.H. Polman ................................................................................................. 79
lIlA. Stem cells: Technology and mobilization
Autologous transplantation of blood versus marrow derived
hemopoietic stem cells
M. Korbling .................................................................................................. 85
Granulocyte macrophage progenitor numbers in peripheral
blood stem cell autotransplantation
C.A. Juttner .................................................................................................. 91
Purged autologous bone marrow: Better or worse than
circulating stem cells?
J. Reiffers ................................................................................ : .................. 103
Bone marrow stem cells: Purification and clinical results
T. de Witte ................................................................................................. 113
Collection and transplantation of peripheral hemopoietic
stem cells. Results in 35 patients with hematological and non
hematological malignancies
A. Iacone .................................................................................................... 119
IIIB. Stem cells: Clinical Application
Peripheral blood stem cell transplants in myeloma
T.J. Hamblin .............................................................................................. 133
High dose chemotherapy and blood stem cell autologous graft
in multiple myeloma
J.P. Fermand .............................................................................................. 139
Stem cell harvesting from umbilical cord blood: A new
perspective
E. Gluckman .............................................................................................. 145
Circulating stem cells for autografting: A perspective for
hematopoietic growth factors
H.H. Gerhartz ............................................................................................ 153
IV. In vivo versus ex vivo modulation of lymphocytes
In vivo versus ex vivo modulation of lymphocytes;
Immunotherapy for hematological malignancies
D. van der Harst ........................................................................................ 159
IX
The promise of T cell immunotherapy of cancer
C.J.M. Melief ............................................................................................. 165
Photopheresis: A new approach to the management of T-cell
mediated disorders
R. Edelson .................................................................................................. 173
High levels of circulating hematopoietic progenitor cells after
continuous infusion of high dose interleukin-2 in cancer
patients
M.R. Schaafsma ........................................................................................ 189
V. Single versus multiple donor platelets
Is leukocyte depletion important in the prevention of
alloimmunization by random single donor platelet transfusion?
J. Gmiir ....................................................................................................... 197
UV -irradiation: Effects on the immune system and on platelet
function, viability, and alloimmunization
S.J. Slichter ................................................................................................ 205
Purification of platelet concentrates by elutriation: Elutriated
single versus pooled multiple donor platelets
M.K. Elias .................................................................................................. 229
Platelet concentrates from buffy coats
F. Bertolini ................................................................................................. 245
Selection of platelet apheresis donors for alloimmunized
patients by ELISA platelet crossmatch versus HLA-matching
K. Sintnicolaas .......................................................................................... 255
Index ........................................................................................................... 263
XI
MODERA TORS AND SPEAKERS
Edwin Cohn-de Laval Awards 1990
Prof. Dr. W.J. Kolff Kolff's Laboratory, Dept. of Surgery Univer
sity of Utah, Saltlake City, UT, USA
Dr. 1. Djerassi Mercy Catholic Medical Center,
Philadelphia, PA, USA
Invited speakers
Plasmapheresis: Centrifugation versus filtration
Prof. Dr. H.J. Gurland Dept. of Nephrology, Klinikum Grosshadern,
University of Munich, Munich, FRG
Dr. P. Konstantin Fresenius AG, St. Wendel, FRG
Prof. M.Y. Jaffrin Dept. Genie Biologique, Compiegne, F
Dr. A.A. Kaplan Div. of Nephrology, University of Connecti
cut, Farmington, CT, USA
Dr. R.R. Stromberg Jerome T. Holland Laboratory, American
Red Cross, Rockville, MD, USA
Plasmapheresis in neurology
Prof. Dr. R.A.C. Hughes Dept. of Neurology, Guy's Hospital, Lon
don, UK
Dr. J.C. Raphael Service de Reanimation Medicale, H6pital
Raymond Poincare, Garches, F
Dr. F.G.A. v.d. Meche Dept. of Neurology, University Hospital
Dijkzigt, Rotterdam, NL
XII
Dr. B.P. Khatri Center for Neurological Diseases, Milwau
kee, WI, USA
Dr. C.H. Polman Dept. of Neurology, Free University Hospi
tal, Amsterdam, NL
Stem cells: Technology and mobilization
Dr. M. K6rbling Dept. of Internal Medicine, Heidelberg
University, Heidelberg, FRG
Dr. C.A. Juttner Div. of Haematology, Inst. of Medical and
Veterinary Science, Adelaide, AUS
Prof. J. Reiffers Unite de Greffe de Moelle Osseuse, Hopital
Haut Leveque, Pessac, F
Prof. Dr. T. de Witte Div. of Haematology, University Hospital,
Nijmegen, NL
Dr. A. Iacone Dept. of Haematology and Blood Bank,
Civil Hospital, Pescara, I
Stem cells: Clinical application
Prof. T.J. Hamblin Royal Victoria Hospital, Bournemouth, UK
Dr. J.P. Fermand Service d'lmmuno-Hematologie, Hopital
Saint-Louis, Paris, F
Dr. E. Gluckman Bone Marrow Transplant Unit, Hopital
Saint-Louis, Paris, F
Dr. H.H. Gerhartz Medical Dept. III, Klinikum Grosshadern,
University of Munich, Munich, FRG
In vivo modulation versus ex vivo modulated lymphocytes
Dr. D. van der Harst Dept. of Immunohaematology and Blood
Bank, University Hospital, Leiden, NL
Prof. Dr. C.J.M. Melief Div. of Immunology, The Netherlands
Cancer Institute, Amsterdam, NL
Dr. R.L. Edelson Dept. of Dermatology, Yale University,
New Haven, CT, USA
Dr. M.R. Schaafsma Lab. of Experimental Haematology, Dept.
of Haematology, University Medical Center,
Leiden, NL