Description:This book constitutes the refereed proceedings of the 18th International Conference on Advanced Information Systems Engineering, CAiSE 2006, held in Luxembourg, Luxembourg in June 2006.The 33 revised full papers presented together with 3 keynote talks were carefully reviewed and selected from 189 submissions. The papers are organized in topical sections on security, conceptual modelling, queries, document conceptualization, service composition, workflow, business modelling, configuration and separation, business process modelling, agent orientation, and requirements management.