Adnexal Tumors of the Skin: An Atlas

137 Pages·1987·5.301 MB·English

by  Dr. Kinya Ishikawa (auth.)

Kinya Ishikawa
Adnexal Tumors
of the Skin
An Atlas
With 116 Figures
Springer-Verlag
Tokyo Berlin Heidelberg New York
London Paris
Dr. KINY A ISHIKAwA
Department of Dermatology
Kasumigaura National Hospital
7-14, Shimotakatsu 2-chome
Tsuchiura, 300 Japan
Library of Congress Cataloging-in-Publication Data
Ishikawa, Kinya, 1923-
Adnexal tumors of the skin.
Includes bibliographies and index. 1. Skin-Tumors-Atlases. 2. Hair follicles
-Tumors-Atlases. 3. Sweat glands---Tumors-Atlases. I. Title. [DNLM:
I. Skin Appendage Diseases-pathology-atlases. 2. Skin Neoplasms-pathology
-atlases. 3. Sweat Gland Neoplasms-pathology-atlases. WR 17 I79a]
RC280.s5I84 1987 616.99'2770758 87-4603
ISBN-13: 978-4-431-68056-7 e-ISBN-13: 978-4-431-68054-3
DOl: 10.1007/978-4-431-68054-3
This work is subject to copyright. All rights are reserved, whether the whole or part
of the material is concerned, specifically the rights of translation, reprinting, reuse
of illustrations, recitation, broadcasting, reproduction on microfilms or in other
ways, and storage in data banks.
© Springer-Verlag Tokyo 1987
Softcover reprint of the hardcover I st edition 1987
The use of registered names, trademarks, etc. in this publication does not imply, even
in the absence of a specific statement, that such names are exempt from the relevant
protective laws and regulations and therefore free for general use.
Product liability: The publisher can give no guarantee for information about drug
dosage and application thereof contained in this book. In every individual case
the respective user must check its accuracy by consulting other pharmaceutical
literature.
Typesetting: Asco Trade Typesetting Ltd., Hong Kong
Preface
Toward a full understanding of the skin adrexa and associated tumors,
an accurate and detailed visual record of the various structures en
countered is essential. Such a comprehensive survey has, however, hith
erto been lacking in works on dermatology; this situation I attempt to
remedy in the present atlas by presenting a collection of my own cases
over the years. I took almost all the photomicrographs myself using a
Nikon Biophot microscope.
I would like to express my deep gratitude to Prof. Hitoshi Hatano,
Department of Dermatology, School of Medicine, Keio University, who
reviewed this book and consented to its publication. I am especially
grateful to Dr. Junya Fukuda, Chief Pathologist, Kawasaki Municipal
Hospital, who helped in diagnosing routine histological sections of the
skin and gave invaluable advice with this book. I am enormously in
debted to Mr. Soichi Narutomi, Chief Technician, Section of Pathology,
Kawasaki Municipal Hospital, who produced first-class prints from
35-mm films. I must express my deep thanks to the late Mr. Shin
Takeichi, Head of Photography, Department of Pathology, School of
Medicine, Keio University, who kindly took photomicrographs for me
for many years; some of these are included in the present volume. lowe
a great deal to Associate Prof. Kan Niizuma, Department of Derma
tology, School of Medicine, Tokai University, who kindly arranged for
this book to be published by Springer-Verlag. Finally, I should like to
acknowledge the efforts and goodwill of Springer-Verlag Tokyo.
Spring, 1987 KINYA ISHIKAWA
Contents
Structure of the Adnexa .
Hair follicle. . . . 2
Normal structure 2
Hair cycle. . . . 26
Sebaceous follicle of face 36
Compound follicle. . . 38
Mantle hair. . . . . . 40
Basal cell epitheliomalike changes of hair follicle in
dermatofibroma . 42
Apocrine glands. . . . . . . . . . . . . . . . 44
Eccrine glands. . . . . . . . . . . . . . . . . 48
Eccrine sweat glands with clear reticulated cytoplasm 54
Dilatation and proliferation of sweat ducts. 56
Abnormalities of eccrine sweat ducts . . . . . . . 58
Tumors of the Adnexa. 63
Cysts. . . . . . . . 64
Trichilemmal cyst . 64
Steatocystoma multiplex 66
Dermoid cyst . 68
Follicular tumors . . . . 70
Inverted follicular keratosis 70
Trichilemmoma . . . 72
Calcifying epithelioma 74
Hair follicle nevus 77
Trichofolliculoma . 78
Trichoepithelioma . 80
Trichogenic tumors. 82
Sebaceous tumors . . 84
Fordyce's condition 84
Nevus sebaceus . . 86
Senile sebaceous hyperplasia. 88
Sebaceous epithelioma . . . 90
Apocrine tumors. . . . . 92
Supernumerary nipple . 92
Apocrine hidrocystoma . 94
Syringocystadenoma papilliferum. 96
Hidradenoma papilliferum 98
Eccrine tumors . . . . 100
Eccrine hidrocystoma. 100
Syringoma . . . . . 102
Eccrine poroma . . . 104
Hidroacanthoma simplex 106
Dermal duct tumor. . . 108
Eccrine spiradenoma. . 110
Clear cell hidradenoma . 112
Solid-cystic hidradenoma 114
Chondroid syringoma 116
Basal cell epithelioma. . . 118
Stellar atrophy . . . . 124
Superficial basal cell epithelioma. 126
Premalignant fibroepithelial tumor 128
Subject Index . . . . . . . . . . . . . . . . . . . .. 131
VIII
Structure of the Adnexa
Structure of the adnexa ____________________________
HAIR FOLLICLE
Normal structure
REFERENCES
I Pinkus H (1967) Pathobiology of the pilary complex. Jpn J Dermatol Ser B 77: 304-330
2 Pinkus H (1968) Static and dynamic histology and histochemistry of hair growth. In: Baccaredda-Boy
A, Moretti G, Frey JR (eds) Biopathology of pattern alopecia. Karger, Basel, pp 69-81
3 Pmkus H (1978) Epithelial-mesodermal interaction in normal hair growth, alopecia, and neoplasia.
J Dermatol (Tokyo) 5: 93-101
2
FIg. 1. Matrix area of an anagen hair follicle. The fibrous root sheath protrudes into the bell-shaped hair
bulb and forms the dermal papilla, in which papilla cells are seen to be crowded. The specific differentia
tion of the matrix cells, which is shown m the following figures, IS determmed by the dermal papilla; it
is especially influenced by the linear distance of the cells from the base of the papilla [1-3].
Hand E, x 160
3
Structure of the adnexa· Hair follicle' Normal structure ________________
Figures 2-15 are photomicrographs of a huge hair follicle found in a section of
intradermal nevus on the neck of a 26-year-old man. Because the hair follicle is
somewhat obliquely sectioned, all of the dermal papilla is confined within the hair
bulb.
FIg. 2. The hair matrix portion. Six kinds ofpilar.keratmocyte are differentiating from the outside to the [>
inside of the hair matrix: (I) Henle's layer (He), (2) Huxley's layer (Hu), (3) cuticle of the inner root
sheath (CI), (4) cuticle of the hair (CH), (5) hair cortex (Co), and (6) hair medulla (M). Lateral to these,
three sheaths are seen: (I) outer root sheath (ORS), (2) vitreous (or glassy) membrane (VM), and (3) fi
brous root sheath (FRS).
Hand E, x 500
4