ADHD COMORBIDITIES Handbook for ADHD Complications in Children and Adults This page intentionally left blank ADHD COMORBIDITIES Handbook for ADHD Complications in Children and Adults Edited by Thomas E. Brown, Ph.D. Washington, DC London, England Note: The authors have worked to ensure that all information in this book is accurate at the time of publication and consistent with general psychiatric and medical standards, and that information concerning drug dosages, schedules, and routes of administration is accurate at the time of publication and consistent with standards set by the U.S. Food and Drug Administration and the general medical community. As medical research and practice con- tinue to advance, however, therapeutic standards may change. Moreover, specific situations may require a specific therapeutic response not included in this book. 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ALL RIGHTS RESERVED Manufactured in the United States of America on acid-free paper 12 11 10 09 08 5 4 3 2 1 First Edition Typeset in Adobe Berling and Franklin Gothic American Psychiatric Publishing, Inc. 1000 Wilson Boulevard Arlington, VA 22209–3901 www.appi.org Library of Congress Cataloging-in-Publication Data ADHD comorbidities : handbook for ADHD complications in children and adults / edited by Thomas E. Brown.— 1st ed. p. ; cm. Includes bibliographical references and index. ISBN 978-1-58562-158-3 (alk. paper) 1. Attention-deficit hyperactivity disorder—Complications—Handbooks, manuals, etc. 2. Attention-deficit dis- order in adults—Complications—Handbooks, manuals, etc. I. Brown, Thomas E., Ph. D. [DNLM: 1. Attention Deficit Disorder with Hyperactivity—epidemiology. 2. Adolescent. 3. Adult. 4. Child. 5. Comorbidity. 6. Mental Disorders—epidemiology. WS 350.8.A8 A2335 2009] RJ506.H9A323 2009 618.92'8589—dc22 2008037968 British Library Cataloguing in Publication Data A CIP record is available from the British Library. SFI FPO To my wife, Bobbie, with love and gratitude for all you are, all you give, and al(cid:1)l we share together. Perhaps the most indispensable thing we can do as human beings, every day of our lives, is remind ourselves and others of our complexity, fragility, finiteness and uniqueness. Antonio R. Damasio (1994) Descartes’ Error: Emotion, Reason and the Human Brain CONTENTS Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi Foreword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xv F. Xavier Castellanos, M.D. Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xvii Acknowledgments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xxi PART I ATTENTION DEFICIT DISORDERS IN DEVELOPMENTAL CONTEXTS 01 Developmental Complexities of Attentional Disorders. . . . . . . . . . . . . 3 Thomas E. Brown, Ph.D. 02 Genetics of ADHD. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 David C. Rettew, M.D. James J. Hudziak, M.D. 03 ADHD in Preschool Children . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 Kelly Posner, Ph.D. Aliza W. Pressman, M.A. Laurence L. Greenhill, M.D. 04 ADHD in Elementary School Children. . . . . . . . . . . . . . . . . . . . . . . . . . 55 George J. DuPaul, Ph.D. Thomas J. Power, Ph.D. 05 ADHD in Adolescents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 Arthur L. Robin, Ph.D. 06 ADHD in Adults . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81 Lily Hechtman, M.D., F.R.C.P. PART II ATTENTION DEFICIT DISORDERS WITH SPECIFIC COMORBIDITIES 07 ADHD With Mood Disorders. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97 Gabrielle A. Carlson, M.D. Stephanie E. Meyer, Ph.D. 08 ADHD With Anxiety Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131 Rosemary Tannock, Ph.D. 09 ADHD With Oppositionality and Aggression. . . . . . . . . . . . . . . . . . . . 157 Jeffrey H. Newcorn, M.D. Jeffrey M. Halperin, Ph.D. Carlin J. Miller, Ph.D. 10 ADHD With Obsessive-Compulsive Disorder. . . . . . . . . . . . . . . . . . . . 177 Daniel A. Geller, M.B.B.S., F.R.A.C.P. Thomas E. Brown, Ph.D. 11 ADHD With Language and/or Learning Disorders in Children and Adolescents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189 Rosemary Tannock, Ph.D. Thomas E. Brown, Ph.D. 12 ADHD and Learning Disabilities in Adults: Overlap With Executive Dysfunction . . . . . . . . . . . . . . . . . . . . . . . . . . 233 Jeanette Wasserstein, Ph.D. Martha Bridge Denckla, M.D. 13 ADHD With Substance Use Disorders. . . . . . . . . . . . . . . . . . . . . . . . . 249 Timothy E. Wilens, M.D. 14 ADHD With Autism Spectrum Disorders. . . . . . . . . . . . . . . . . . . . . . . 265 Christopher Gillberg, M.D., Ph.D. Paramala J. Santosh, M.B.B.S., Dip.N.B. (Psych.), M.R.C.Psych., M.D. Thomas E. Brown, Ph.D. 15 ADHD With Sleep/Arousal Disturbances. . . . . . . . . . . . . . . . . . . . . . 279 Judith A. Owens, M.D., M.P.H. Thomas E. Brown, Ph.D. Edward J. Modestino, M.Phil. 16 ADHD With Tourette Syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293 Denis G. Sukhodolsky, Ph.D. Lawrence Scahill, M.S.N., Ph.D. James F. Leckman, M.D. 17 ADHD With Developmental Coordination Disorder . . . . . . . . . . . . . . 305 Christopher Gillberg, M.D., Ph.D. Björn Kadesjö, M.D., Ph.D. PART III ASSESSMENT AND INTERVENTIONS FOR COMPLICATED ATTENTION DEFICIT DISORDERS 18 Assessment of ADHD and Comorbidities . . . . . . . . . . . . . . . . . . . . . . 317 Donald M. Quinlan, Ph.D. 19 Pharmacotherapy of ADHD and Comorbidities . . . . . . . . . . . . . . . . . 339 Jefferson B. Prince, M.D. Timothy E. Wilens, M.D. 20 Psychosocial Interventions for ADHD and Comorbidities. . . . . . . . . 385 Stephen P. Hinshaw, Ph.D. 21 Cognitive Therapy for Adults With ADHD . . . . . . . . . . . . . . . . . . . . . . 399 Stephen P. McDermott, M.D. 22 Tailoring Treatments for Individuals With ADHD and Their Families. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 415 Peter S. Jensen, M.D. Howard Abikoff, Ph.D. Thomas E. Brown, Ph.D. Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 429