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AUTHOR INDEX Bold type indicates authors of commentaries, editorials, letters, and Resource Corners; (No.) indicates issue number. Abraham E, 43 Cook DJ, 53 Hart SL, 44 Abuissa H, 64 Cook NR, 8, 9 Harvey S, 21 Adam DJ, 69 Cornel JH, 30 Hasselblad V, 70 Adams LA, 22 Correa-de-Araujo R, 23 Hayden JA, 12-13 Ageno W, 46-47 Cullen M, 42 Heathcote EJ, 4 Akl EA, 80 Dagerman KS, 36 Henry JC, 35 Albertsson K, 73 Dahlof B, 32 Heneghan C, A-8—A-11 (No.2) Alder SC, 81 Darbinian J, 78 Hillegass WB, 52, 60-61 Allaart CF, 72 De Francesco V, 2 Hirsch C, 36 Al-Roomi K, 35 de Vries-Bouwstra JK, 72 Hirsh J, 18 Ameratunga S, A-8—A-11 (No.2) de Winter RJ, 30 Hlatky MA, 52 Aoun M, 3 Debley C, 71 Hoes AW, 47 Aranow C, 74 Denman M, 75 Holloway R, 35 Auble TE, 80 Devereaux PJ, 17 Hsu CY, 78 Avenell A, 14 Dickinson JA, A-10—A-11 (No. 1) Huffman LH, 37 Ayas NT, 49 Doll H, A-8—A-9 (No. 3) Hughes S, 60 Backlund JC, 63 Dooley MA, 74 Hunter DJ, 72 Baigent C, 62 Dormandy JA, 34 lestra JA, 16 Barter P, 65 Ebrahim S, 79 Imazio M, 31 Bateman K, 81 Eckland DJ, 34 Insel P, 36 Beard JD, 69 Ensrud KE, 10 Ioannou G, 71 Beattie WS, 17 Fahey T, 79 Iribarren C, 78 Beck-Bornholdt HP, 19 Falck-Ytter Y, A-8—A-9 (No. 1) Isley WL, 34 Becx P, 20 Ferrone CR, 77 Jackson R, A-8—A-11 (No.2) Ben Porat L, 77 Filippatos GS, 21 Jamal SA, 10 Berger PB, 15 Finne P, 51 Johnell O, 14 Bergmann JE, 4-5 FitzGerald JM, 49 Jones PG, 64 Bilezikian JP, 10 Flather M, 31 Julian L, 44 Billingham L, 42 Fletcher L, 1 Kaduszkiewicz H, \o Black DM, 10 Flossmann E, 24 Kagansky M, 71 Black HR, 25 Fraser A, 3, 57 Kagansky N, 71 Bleck TP, 20 Fu R, 37 Kalra S, 17 Bobbio M, 31 Fugate Woods N, 23 Kalunian KC, 75 Boonen A, 73 Gafter-Gvili A, 57 Kaplan RC, 50 Boulton MR, A-10—A-11 (No. 1) Garcia- Tsao G, 68 Kearney PM, 62 Borok S, 3 Garg R, 43 Keech A, 62, 65 Borzak S, 29 Gatta L, 2 Kim MY, 75 Bosch J, 68 Gaziano JM, 8, 9 King DB, A-10—A-11 (No. 1) Broad J, A-8—A-11 (No.2) Gea-Banacloche JC, 42 Kiss A, 61 Brunet F, 61 Gershlick AH, 60 Kitchens J, 17 Bruyninckx F, 20 Gerstein HC, 11, 63 Knudsen CW, 48 Bucaneve G, 40 Gibson CM, 29 Koes BW, 12-13 Cannon CP, 29 Giles MF, 24 Korula J, 68 Cantor WJ, 61 Gillespie LD, 14 Krane V, 7 Carey TS, 12-13 Gillespie WJ, 14 Kremastinos DT, 21 Carlberg B, 67 Ginzler EM, 74 Krishnan P, 35 Carlet J, 43 Glasziou P, A-8—A-11 (No. 2) Kromhout D, 16 Carney S, A-8—A-9 (No. 3) Go AS, 78 Kunz R, A-8—A-9 (No. 1) Cecchi E, 31 Goekoop-Ruiterman YP, 72 Lacasse Y, 66 Chambers S, 1 Goodacre S, 46 LaCroix AZ, 23 Charbonnel B, 34 Granger C, 25 Laterre PF, 43 Chiba N, 2 Gray SL, 23 Lau GK, 5 Choi PT, 17 Groszmann RJ, 68 Lee IM, 8, 9 Cleary PA, 63 Gulati M, 25 Legemate DA, 69 Clement CM, 53 Gutknecht D, 11, 79 Leibovici L, 1 Cleveland T, 69 Guyatt G, A-8-A-9 (No. 1) Leighton JA, 76 Clopton P, 48 Hadziyannis SJ, 4 Leontiadis GI, 76 Cohn JN, 48 Hall MJ, 37 Lethaby A, A-8—A-11 (No.2) Collins JE, 6 Hankey GJ, 50 Lindbaek M, 81 Collinson J, 31 Harris EL, 37 Lindholm LH, 67 COMMIT Collaborative Group, 58 Harrison DA, 21 Longstreth WT Jr, 50 Connor J, A-8—A-11 (No.2) Hart R, 24 Loprinzi CL, 41 ACP JOURNAL CLUB MAY/JUNE 2006 |V OLUME 144 ¢ NUMBER 3 AUTHOR INDEX Luckmann R, 19 Pavlakis N, 39 Stephens-Lloyd A, 60 Luo KX, 5 Peterson W, 76 Steven N, 42 Lymp JF, 22 Petri M, 75 Stevens SM, 46-47 Magrini N, A-8-A-9 (No. 1) PiratvisuthT , 5 Stevenson LW, 70 Mak E, 49 Pict B, 15 Stiell IG, 53 Malmivaara AV, 12-13 Poulter NR, 32 Stockler M, 39 Manns B, 74 Prasad K, 35 Stone RA, 80 Marmor E, 38 Qushmag I, 53 Suarez A, 60-61 Marso SP, 64 Rajdev S, 60-61 Sutton AJ, 46 Marz W, 7 Ramsay RE, 6 Svensson B, 73 Massel D, 59 Regine WE, 38 Szajewska H, 45 Mayes BN, 6 Reichen J, 22 Tassopoulos NC, 4 McCarthy W, 77 Rembold C, 62 Tattersall M, 40 McCulloch CE, 78 Reunanen A, 51 Tepper J, 33 McElderry HT Jr, 52 Richards D, 1 The PREPIC Study Group, 18 McQueen M, 65 Rimon E, 71 Tibbs PA, 38 Menichetti F, 40 Robb G, A-8—A-11 (No.2) Tirschwell DL, 50 Micozzi A, 40 Roscoe JA, 41 Tomlinson G, 12-13 Mihara H, 33 Rothwell PM, 24 Toop L, 1 Mohr DC, 44 Rowan AJ, 6 Toumpas C, A-10—A-11 (No. 1) Moist L, 7 Rowe BH, 53 Triester SL, 76 Moons KG, 47 Rudd P, 67 U.S. Preventive Services Task Force, 37 Morrison LJ, 61 Sabatine MS, 29 Van den Berghe G, 20 Morrow GR, 41 Salpeter E, 66 van den Bussche H, 19 Moyer CD, 15 Salpeter S, 66 van der Schouw YT, 16 Mrukowicz J, 45 Samore MH, 81 van Tulder MW, 12-13 Nardone DA, A-11 (No. 3) Sampson FC, 46 Vist G, A-8—A-9 (No. 1) Nathan DM, 63 Samuelsson O, 67 Walsh M, 74 Nelson HD, 37 Sanders GD, 52 Wang CS, 49 Neugut Al, 37 Schattner A, 73 Wanner C, 7 Nicolau J, 15 Schmidt RL, 39 Wells S, A-8—A-11 (No.2) O’Hare A, 78 Schneider LS, 36 Welsford M, 30 O'Keefe JH Jr, 64 Schoonheydt K, 20 White H, 15 O'Connell DL, 14 Schroeder K, 79 Wiedemann HP, 70 O'Regan R, 39 Schulzer M, 49 Willett LR, 8-9 Omiston T, 66 Schiinemann H, 21, A-8—A-9 (No. 1) Windhausen F, 30 Omland T, 48 Schuster M, 57 Winkelmayer WC, 51 Ost D, 33 Sensky T, 44 Witt DM, 33 Ostergren JB, 11 Sequeira R, 35 Wouters PJ, 20 Oudega R, 47 Sever PS, 32 Wyer PC, 49, A-11 (No. 3) Owens DK, 52 Shah MR, 70 Yealy DM, 80 Padwal R, 64 Shaw LJ, 25 York M, 72 Panageas KS, 77 Simes RJ, 65 YusufS , 11 Pandya KJ, 41 Singer M, 21 Zarnke KB, 32 Parker M, A-10 (No.3) Siragusa S, 33 Ziegler CP, 61 Parrino TA, 45 Smith D, 16 Zimmermann T, 19 Patchell RA, 38 St. Sauver J, 22 Zullo A, 2 Paul M, 3, 57 Stenman S, 51 86 oaAcP MAY/JUNE 2006 VOLUME 144 e NUMBER 3 ACP JOURNAL CLUB JECT INDEX A A clinical decision support system reduced antimicrobial use for a-Tocopherol acute respiratory tract infections in rural settings, 81 Vitamin E did not prevent cardiovascular disease and cancer in Levofloxacin prevented fever and infection during prolonged healthy women, 8-9 chemotherapy-induced neutropenia, 40 Adenine Review: Additional anti-gram-positive antibiotics do not reduce The benefits of adefovir dipivoxil for HBeAg-negative chronic all-cause mortality in cancer and febrile neutropenia, 3 Review: Saccharomyces boulardii reduces risk for antibiotic-associated hepatitis B did not persist after discontinuation of treatment, 4 diarrhea, 45 Adrenergic B-antagonists Antibiotic prophylaxis Amlodipine plus perindopril was better than atenolol plus Antibacterial prophylaxis reduced the incidence of fever in patients bendroflumethiazide for reducing complications in hypertension, 32 A nonselective B-blocker did not prevent gastroesophageal varices in receiving chemotherapy for solid tumors or lymphoma, 42 cirrhosis and portal hypertension, 68 Levofloxacin prevented fever and infection during prolonged chemotherapy-induced neutropenia, 40 Review: B-blockers are less effective than other antihypertensive Review: Antibiotic prophylaxis reduces mortality in patients with drugs for reducing risk for stroke in primary hypertension, 67 neutropenia after chemotherapy, 57 Review: Cardioselective B-blockers do not produce adverse Anticoagulants respiratory effects in COPD, 66 Pioglitazone did not reduce a composite endpoint of macrovascular Review: Evidence of benefit for perioperative B-blockers in complications and increased risk for heart failure in type 2 noncardiac surgery is unreliable, 17 diabetes with macrovascular disease, 34 Alendronate Anticonvulsants 1 year of alendronate after 1 year of parathyroid hormone (1-84) Lamotrigine or gabapentin was better tolerated than carbamazepine treatment increased bone mineral density in osteoporosis, 10 in new-onset geriatric epilepsy, 6 Alzheimer disease Review: Lorazepam provides the best control for status epilepticus, 35 Review: Cholinesterase inhibitors may be effective in Alzheimer Antihypertensive agents disease, 19 Review: Care assisted by nurses or pharmacists provides better blood Amines pressure control, 79 900 mg daily of gabapentin was effective for hot flashes in women Antiinfective agents with breast cancer, 41 Drotrecogin- (activated) did not reduce death and increased bleeding Amputation in patients with severe sepsis and low risk for death, 43 Bypass surgery and balloon angioplasty did not differ for Trimethoprim reduced dysuria in women with symptoms ofu rinary amputation-free survival in severe limb ischemia, 69 tract infection but negative urine dipstick test results, 1 Anemia, iron-deficiency Antiinflammatory agents Low-dose iron supplementation was effective in older patients with Addition of clopidogrel to aspirin, but not early use of metoprolol, iron-deficiency anemia, 71 improved overall outcome in acute myocardial infarction, 58-59 Angina, unstable First-line treatment with colchicine reduced recurrent pericarditis, 31 An early invasive strategy was not better than a selectively invasive Antilipemic agents strategy for acute coronary syndromes, 30 Long-term fenofibrate therapy did not reduce major coronary events Angioplasty but may reduce total CVD events in type 2 diabetes mellitus, 65 Bypass surgery and balloon angioplasty did not differ for Antineoplastic agents amputation-free survival in severe limb ischemia, 69 Antibacterial prophylaxis reduced the incidence of fever in patients Clopidogrel before percutaneous coronary intervention reduced receiving chemotherapy for solid tumors or lymphoma, 42 cardiovascular outcome in ST-elevation myocardial infarction, 29 Review: Antibiotic prophylaxis reduces mortality in patients with An early invasive strategy was not better than a selectively invasive neutropenia after chemotherapy, 57 strategy for acute coronary syndromes, 30 Review: Bisphosphonates prevent or delay skeletal events in women Rescue angioplasty reduced cardiovascular and cerebrovascular with advanced breast cancer and bone metastases, 39 outcomes in acute MI] after failed thrombolytic therapy, 60-61 Antipsychotic agents Review: Evidence supporting reduced death and reinfarction by Review: Atypical antipsychotic drugs increase risk for death in percutaneous coronary intervention after thrombolysis is dementia, 36 inconclusive, 60-61 Antirheumatic agents Angiotensin II type 1 receptor blockers Initial combination therapy with prednisone or infliximab improved Candesartan prevented development ofd iabetes mellitus in heart outcomes in early rheumatoid arthritis more than DMARDs failure, 11 alone, 72 Review: Angiotensin-converting enzyme inhibitors and Prednisolone plus a disease-modifying antirheumatic drug improved angiotensin-receptor blockers prevent type 2 diabetes, 64 outcomes in early rheumatoid arthritis, 73 Angiotensin-converting enzyme inhibitors Antiviral agents Review: Angiotensin-converting enzyme inhibitors and The benefits of adefovir dipivoxil for HBeAg-negative chronic angiotensin-receptor blockers prevent type 2 diabetes, 64 hepatitis B did not persist after discontinuation of treatment, 4 Antibacterial agents Peginterferon O-2a alone or with lamivudine increased response Antibacterial prophylaxis reduced the incidence of fever in patients rates more than lamivudine alone for HBeAg-positive chronic receiving chemotherapy for solid tumors or lymphoma, 42 hepatitis B, 5 ACP JOURNAL CLUB MAY/JUNE 2006 |V OLUME 144 * NUMBER 3 ©ACP 87 SUBJECT INDEX Arthritis, rheumatoid Cardiovascular diseases Initial combination therapy with prednisone or infliximab improved Amlodipine plus perindopril was better than atenolol plus outcomes in early rheumatoid arthritis more than DMARDs bendroflumethiazide for reducing complications in alone, 72 hypertension, 32 Prednisolone plus a disease-modifying antirheumatic drug improved Intensive insulin therapy reduced cardiovascular disease in type 1 outcomes in early rheumatoid arthritis, 73 diabetes, 63 Aspirin Long-term fenofibrate therapy did not reduce major coronary events Addition ofc lopidogrel to aspirin, but not early use of metoprolol, but may reduce total CVD events in type 2 diabetes mellitus, 65 improved overall outcome in acute myocardial infarction, 58-59 Recurrent stroke rate was higher than coronary heart disease rate in Low-dose aspirin did not prevent cancer in healthy women, 8-9 the first year after stroke but similar after the first year, 50 Atenolol Review: Evidence ofb enefit for perioperative B-blockers in Review: B-blockers are less effective than other antihypertensive noncardiac surgery is unreliable, 17 drugs for reducing risk for stroke in primary hypertension, 67 Vitamin E did not prevent cardiovascular disease and cancer in Atrial fibrillation healthy women, 8-9 B-type natriuretic peptide level had reduced specificity for diagnosing Catheterization, swan-ganz heart failure in dyspnea with atrial fibrillation in the emergency Management with a pulmonary artery catheter did not reduce all- department, 48 cause mortality in critically ill patients, 21 Review: A pulmonary artery catheter does not reduce mortality or B hospital days in critically ill patients, 70 Cerebrovascular disorders Bacterial infections Acorvastatin did not prevent cardiovascular events or death in Antibacterial prophylaxis reduced the incidence of fever in patients patients with type 2 diabetes receiving hemodialysis, 7 receiving chemotherapy for solid tumors or lymphoma, 42 Recurrent stroke rate was higher than coronary heart disease rate in Levofloxacin prevented fever and infection during prolonged the first year after stroke but similar after the first vear, 50 chemotherapy-induced neutropenia, 40 Review: Atypical antipsychotic drugs increase risk for death in Review: Antibiotic prophylaxis reduces mortality in patients with dementia, 36 neutropenia after chemotherapy, 57 A simple risk score predicted 7-day stroke risk after transient Biostatistics ischemic attack, 24 Introduction to biostatistics: Part 3. Statistical approaches to Cholesterol uncertainty: P values and confidence intervals unpacked Long-term fenofibrate therapy did not reduce major coronary events (Editorial), A-8—A-9 (No. 3) but may reduce total CVD events in type 2 diabetes mellitus, 65 Bisphosphonates Cholinesterase inhibitors Review: Bisphosphonates prevent or delay skeletal events in women Review: Cholinesterase inhibitors may be effective in Alzheimer with advanced breast cancer and bone metastases, 39 Body mass index disease, 19 Cirrhosis Being overweight or obese was associated with a greater risk for A nonselective B-blocker did not prevent gastroesophageal varices in end-stage renal disease, 78 cirrhosis and portal hypertension, 68 Bone density conservation agents Clinical skills Review: Bisphosphonates prevent or delay skeletal events in women with advanced breast cancer and bone metastases, 39 Clinical skills textbooks fail evidence-based examination (Editorial), A-10—A-11 (No. 1) Bone neoplasms Cognitive therapy Review: Bisphosphonates prevent or delay skeletal events in women Cognitive behavioral therapy delivered by telephone reduced with advanced breast cancer and bone metastases, 39 depression in multiple sclerosis with functional impairment, 44 Breast neoplasms Colchicine 900 mg daily of gabapentin was effective for hot flashes in women First-line treatment with colchicine reduced recurrent pericarditis, with breast cancer, 41 31 Review: Bisphosphonates prevent or delay skeletal events in women Contraceptives, oral, combined with advanced breast cancer and bone metastases, 39 Oral contraceptives did not increase risk for flare in women with Review: Only women with specific family histories should be systemic lupus erythematosus, 75 referred for counseling or evaluation for BRCA breast and ovarian Coronary angiography cancer susceptibility, 37 An early invasive strategy was not better than a selectively invasive strategy for acute coronary syndromes, 30 Coronary artery bypass Calcitriol An early invasive strategy was not better than a selectively invasive Review: Vitamin D plus calcium, but not vitamin D alone, prevents strategy for acute coronary syndromes, 30 osteoporotic fractures in older persons, 14 Coronary disease Calcium-channel blockers Pioglitazone did not reduce a composite endpoint of macrovascular Amlodipine plus perindopril was better than atenolol plus ben- complications and increased risk for heart failure in type 2 droflumethiazide for reducing complications in hypertension, 32 diabetes with macrovascular disease, 34 88 ©ACP MAY/JUNE 2006 | VOLUME 144 ¢ NUMBER 3 ACP JOURNAL CLUB SUBJECT INDEX Review: Increased physical activity and combined dietary changes Dyslipidemias reduce mortality in coronary artery disease, 16 Long-term fenofibrate therapy did not reduce major coronary events Craniocerebral trauma but may reduce total CVD events in type 2 diabetes mellitus, 65 The Canadian CT Head Rule was as sensitive as, but more specific Dyspnea than, the New Orleans Criteria for identifying minor head B-type natriuretic peptide level had reduced specificity for diagnosing injury, 53 heart failure in dyspnea with atrial fibrillation in the emergency Critical care department, 48 Intensive insulin therapy reduced the incidence of neurologic Review: Medical history, physical examination, and routine tests are complications in critically ill patients, 20 useful for diagnosing heart failure in dyspnea, 49 Management with a pulmonary artery catheter did not reduce Review: Medical history, physical examination, and routine tests are all-cause mortality in critically ill patients, 21 useful for diagnosing heart failure in dyspnea (Letter), A-11 (No. 3) Review: A pulmonary artery catheter does not reduce mortality or hospital days in critically ill patients, 70 E Cyclohexanecarboxylic acids Early diagnosis 900 mg daily of gabapentin was effective for hot flashes in women A simple risk score predicted 7-day stroke risk after transient with breast cancer, 41 ischemic attack, 24 Cyclooxygenase inhibitors Emergency service, hospital Low-dose aspirin did not prevent cancer in healthy women, 8-9 Moderate- and high-intensity implementation of guidelines Cyclophosphamide increased outpatient care of low-risk pneumonia, 80 Oral mycophenolate led to more complete remissions than Review: Medical history, physical examination, and routine tests are intravenous cyclophosphamide for active lupus nephritis, 74 useful for diagnosing heart failure in dyspnea, 49 Review: Medical history, physical examination, and routine tests are D useful for diagnosing heart failure in dyspnea (Letter), A-11 (No. 3) Endoscopes, gastrointestinal Death, sudden, cardiac Review: Capsule endoscopy has high yield for small bowel findings Prophylactic implantable cardioverter—defibrillators increased life in obscure gastrointestinal bleeding, 76 expectancy with an acceptable cost-effectiveness ratio, 52 Epilepsy Decision support Lamotrigine or gabapentin was better tolerated than carbamazepine The Canadian CT Head Rule was as sensitive as, but more specific in new-onset geriatric epilepsy, 6 than, the New Orleans Criteria for identifying minor head Eplerenone injury, 53 Adjunctive treatment with eplerenone reduced 30-day all-cause A clinical decision support system reduced antimicrobial use for mortality in acute myocardial infarction, 15 acute respiratory tract infections in rural settings, 81 Esophageal and gastric varices Decompression, surgical A nonselective B-blocker did not prevent gastroesophageal varices in Direct decompressive surgery plus radiotherapy improved the ability to cirrhosis and portal hypertension, 68 walk in spinal cord compression caused by metastatic cancer, 38 Evidence-based medicine Defibrillators, implantable Clinical skills textbooks fail evidence-based examination (Editorial), Prophylactic implantable cardioverter—defibrillators increased life expectancy with an acceptable cost-effectiveness ratio, 52 A-10—A-11 (No. 1) An emerging consensus on grading recommendations? (Editorial), Dementia Review: Atypical antipsychotic drugs increase risk for death in A-8—A-9 (No. 1) Evidence-Based to Value-Based Medicine (Resource Corner), A-10 dementia, 36 Depressive disorder (No. 3) The GATE frame: critical appraisal with pictures (Editorial), Cognitive behavioral therapy delivered by telephone reduced depression in multiple sclerosis with functional impairment, 44 A-8—A-11 (No. 2) Introduction to biostatistics: Part 3. Statistical approaches to | Diabetes mellitus, type 1 Incidence of end-stage renal disease in patients with type 1 diabetes uncertainty: P values and confidence intervals unpacked was 7.8% at 30 years after diagnosis, 51 (Editorial), A-8—A-9 (No. 3) Intensive insulin therapy reduced cardiovascular disease in type 1 Exercise diabetes, 63 A nomogram of exercise capacity for age predicted mortality in Diabetes mellitus, type 2 women with cardiovascular symptoms, 25 Review: Exercise therapy reduces pain and improves function in { Atorvastatin did not prevent cardiovascular events or death in patients with type 2 diabetes receiving hemodialysis, 7 chronic but not acute low-back pain, 12-13 Candesartan prevented development ofd iabetes mellitus in heart failure, 11 F Long-term fenofibrate therapy did not reduce major coronary events Family practice but may reduce total CVD events in type 2 diabetes mellitus, 65 Review: Care assisted by nurses or pharmacists provides better blood | Review: Angiotensin-converting enzyme inhibitors and pressure control, 79 angiotensin-receptor blockers prevent type 2 diabetes, 64 Fatty liver Diarrhea Review: Saccharomyces boulardii reduces risk for antibiotic-associated Age, impaired fasting glucose, and cirrhosis predicted mortality at diarrhea, 45 mean 7.6 years for nonalcoholic fatty liver disease, 22 ACP JOURNAL CLUB MAY/JUNE 2006 | VOLUME 144 ¢ NUMBER 3 ©ACP 89 SUBJECT INDEX Ferrous compounds Peginterferon O-2a alone or with lamivudine increased response rates Low-dose iron supplementation was effective in older patients with more than lamivudine alone for HBeAg-positive chronic iron-deficiency anemia, 71 hepatitis B, 5 Fibrinolytic agents Heptanoic acids Rescue angioplasty reduced cardiovascular and cerebrovascular Atorvastatin did not prevent cardiovascular events or death in outcomes in acute MI after failed thrombolytic therapy, 60-61 patients with type 2 diabetes receiving hemodialysis, 7 Hip fractures Fluoroquinolones An operational definition of frailty predicted death, hip fracture, and Review: Antibiotic prophylaxis reduces mortality in patients with hospitalization in older women, 23 neutropenia after chemotherapy, 57 Review: Vitamin D plus calcium, but not vitamin D alone, prevents Fractures osteoporotic fractures in older persons, 14 Review: Vitamin D plus calcium, but not vitamin D alone, prevents Hot flashes osteoporotic fractures in older persons, 14 900 mg daily of gabapentin was effective for hot flashes in women Frail elderly with breast cancer, 41 An operational definition of frailty predicted death, hip fracture, and Hydroxymethylglutaryl-CoA reductase inhibitors hospitalization in older women, 23 Atorvastatin did not prevent cardiovascular events or death in patients with type 2 diabetes receiving hemodialysis, 7 G Review: Cholesterol-lowering treatment with statins reduces Gastrointestinal hemorrhage all-cause mortality in persons at risk, 62 Review: Capsule endoscopy has high yield for small bowel findings Hypercholesterolemia in obscure gastrointestinal bleeding, 76 Review: Cholesterol-lowering treatment with statins reduces all-cause mortality in persons at risk, 62 Genetics Review: Only women with specific family histories should be Hypertension Amlodipine plus perindopril was better than atenolol plus referred for counseling or evaluation for BRCA breast and ovarian bendroflumethiazide for reducing complications in cancer susceptibility, 37 hypertension, 32 Glucocorticoids Review: B-blockers are less effective than other antihypertensive Prednisolone plus a disease-modifying antirheumatic drug improved drugs for reducing risk for stroke in primary hypertension, 67 outcomes in early rheumatoid arthritis, 73 Review: Angiotensin-converting enzyme inhibitors and Gram-positive bacterial infections angiotensin-receptor blockers prevent type 2 diabetes, 64 Review: Additional anti-gram-positive antibiotics do not reduce Review: Care assisted by nurses or pharmacists provides better blood all-cause mortality in cancer and febrile neutropenia, 3 pressure control, 79 Guideline adherence Hypertension, portal Moderate- and high-intensity implementation of guidelines A nonselective B-blocker did not prevent gastroesophageal varices in increased outpatient care of low-risk pneumonia, 80 cirrhosis and portal hypertension, 68 H Heart disease Insulin Adjunctive treatment with eplerenone reduced 30-day all-cause Intensive insulin therapy reduced cardiovascular disease in type 1 mortality in acute myocardial infarction, 15 diabetes, 63 Atorvastatin did not prevent cardiovascular events or death in Intensive insulin therapy reduced the incidence of neurologic patients with type 2 diabetes receiving hemodialysis, 7 complications in critically ill patients, 20 B-type natriuretic peptide level had reduced specificity for Interferon O-2a diagnosing heart failure in dyspnea with atrial fibrillation in Peginterferon O-2a alone or with lamivudine increased response rates the emergency department, 48 more than lamivudine alone for HBeAg-positive chronic Candesartan prevented development of diabetes mellitus in heart hepatitis B, 5 failure, 11 Intestine, small Prophylactic implantable cardioverter—defibrillators increased life Review: Capsule endoscopy has high yield for small bowel findings expectancy with an acceptable cost-effectiveness ratio, 52 in obscure gastrointestinal bleeding, 76 Heart failure, congestive Ischemia Review: Medical history, physical examination, and routine tests are Bypass surgery and balloon angioplasty did not differ for useful for diagnosing heart failure in dyspnea, 49 amputation-free survival in severe limb ischemia, 69 Review: Medical history, physical examination, and routine tests are A simple risk score predicted 7-day stroke risk after transient useful for diagnosing heart failure in dyspnea (Letter), A-11 (No. 3) ischemic attack, 24 Helicobacter pylori A sequential 10-day regimen was better than standard triple therapy for eradicating Helicobacter pylori in older patients, 2 Hepatitis B, chronic Joints The benefits of adefovir dipivoxil for HBeAg-negative chronic Prednisolone plus a disease-modifying antirheumatic drug improved hepatitis B did not persist after discontinuation oftr eatment, 4 outcomes in early rheumatoid arthritis, 73 90 ©ACP MAY/JUNE 2006 |V OLUME 144 ¢ NUMBER 3 ACP JOURNAL CLUB SUBJECT INDEX Review: Evidence supporting reduced death and reinfarction by percutaneous coronary intervention after thrombolysis is Kidney failure, chronic inconclusive, 60-61 Being overweight or obese was associated with a greater risk for N end-stage renal disease, 78 Incidence of end-stage renal disease in patients with type | diabetes Natriuretic peptide, brain was 7.8% at 30 years after diagnosis, 51 B-type natriuretic peptide level had reduced specificity for diagnosing heart failure in dyspnea with atrial fibrillation in the L emergency department, 48 Neoplasms Lamivudine Antibacterial prophylaxis reduced the incidence of fever in patients Peginterferon 0-2a alone or with lamivudine increased response rates receiving chemotherapy for solid tumors or lymphoma, 42 more than lamivudine alone for HBeAg-positive chronic hepatitis B, 5 Family history and dysplastic nevi increased risk for multiple Lifestyle primary melanomas after an initial melanoma, 77 Review: Increased physical activity and combined dietary changes Levofloxacin prevented fever and infection during prolonged reduce mortality in coronary artery disease, 16 chemotherapy-induced neutropenia, 40 Lipoproteins, LDL cholesterol Low-dose aspirin did not prevent cancer in healthy women, 8-9 Review: Cholesterol-lowering treatment with statins reduces Review: Additional anti-gram-positive antibiotics do not reduce all-cause mortality in persons at risk, 62 all-cause mortality in cancer and febrile neutropenia, 3 Lorazepam Vitamin E did not prevent cardiovascular disease and cancer in Review: Lorazepam provides the best control for status epilepticus, 35 healthy women, 8-9 Low back pain Neutropenia Review: Exercise therapy reduces pain and improves function in Levofloxacin prevented fever and infection during prolonged chronic but not acute low-back pain, 12-13 chemotherapy-induced neutropenia, 40 Lupus erythematosus, systemic Review: Additional anti-gram-positive antibiotics do not reduce Oral contraceptives did not increase risk for flare in women with all-cause mortality in cancer and febrile neutropenia, 3 systemic lupus erythematosus, 75 Review: Antibiotic prophylaxis reduces mortality in patients with Lupus nephritis neutropenia after chemotherapy, 57 Oral mycophenolate led to more complete remissions than intravenous cyclophosphamide for active lupus nephritis, 74 O Obesity M Being overweight or obese was associated with a greater risk for Melanoma end-stage renal disease, 78 Family history and dysplastic nevi increased risk for multiple Osteoporosis primary melanomas after an initial melanoma, 77 1 year of alendronate after 1 year of parathyroid hormone (1-84) Menopause treatment increased bone mineral density in osteoporosis, 10 900 mg daily of gabapentin was effective for hot flashes in women Review: Vitamin D plus calcium, but not vitamin D alone, prevents with breast cancer, 41 osteoporotic fractures in older persons, 14 Multiple sclerosis Ovarian neoplasms Cognitive behavioral therapy delivered by telephone reduced Review: Only women with specific family histories should be depression in multiple sclerosis with functional impairment, 44 Mycophenolic acid referred for counseling or evaluation for BRCA breast and ovarian Oral mycophenolate led to more complete remissions than cancer susceptibility, 37 intravenous cyclophosphamide for active lupus nephritis, 74 ( )verweight Myocardial infarction Being overweight or obese was associated with a greater risk for Addition of clopidogrel to aspirin, but not early use of metoprolol, end-stage renal disease, 78 improved overall outcome in acute myocardial infarction, 58-59 Adjunctive treatment with eplerenone reduced 30-day all-cause mortality in acute myocardial infarction, 15 Parathyroid hormone Clopidogrel before percutaneous coronary intervention reduced 1 year of alendronate after 1 year of parathyroid hormone (1-84) cardiovascular outcome in ST-elevation myocardial infarction, 29 treatment increased bone mineral density in osteoporosis, 10 An early invasive strategy was not better than a selectively invasive Patient education strategy for acute coronary syndromes, 30 Pioglitazone did not reduce a composite endpoint of macrovascular Review: Care assisted by nurses or pharmacists provides better blood complications and increased risk for heart failure in type 2 pressure control, 79 diabetes with macrovascular disease, 34 Peptic ulcer Rescue angioplasty reduced cardiovascular and cerebrovascular A sequential 10-day regimen was better than standard triple therapy outcomes in acute MI after failed thrombolytic therapy, 60-61 for eradicating Helicobacter pylori in older patients, 2 ACP JOURNAL CLUB MAY/JUNE 2006 |V OLUME 144 * NUMBER 3 ©ACP 91 SUBJECT INDEX Pericarditis Spinal cord compression First-line treatment with colchicine reduced recurrent pericarditis, 31 Direct decompressive surgery plus radiotherapy improved the ability to Phosphonic acids walk in spinal cord compression caused by metastatic cancer, 38 The benefits of adefovir dipivoxil for HBeAg-negative chronic Spinal neoplasms hepatitis B did not persist after discontinuation of treatment, 4 Direct decompressive surgery plus radiotherapy improved the ability to Physical fitness walk in spinal cord compression caused by metastatic cancer, 38 A nomogram of exercise capacity for age predicted mortality in Status epilepticus women with cardiovascular symptoms, 25 Review: Lorazepam provides the best control for status epilepticus, 35 Platelet aggregation inhibitors Addition of clopidogrel to aspirin, but not early use of metoprolol, T improved overall outcome in acute myocardial infarction, 58-59 Thiazolidinediones Platelet aggregation inhibitors Pioglitazone did not reduce a composite endpoint of macrovascular Clopidogrel before percutaneous coronary intervention reduced complications and increased risk for heart failure in type 2 cardiovascular outcome in ST-elevation myocardial infarction, 29 diabetes with macrovascular disease, 34 Pneumonia Thromboembolism Moderate- and high-intensity implementation of guidelines Review: Long-term anticoagulation reduces recurrent venous increased outpatient care of low-risk pneumonia, 80 thromboembolism, 33 Polyethylene glycols Thrombolytic therapy Peginterferon O-2a alone or with lamivudine increased response Rescue angioplasty reduced cardiovascular and cerebrovascular rates more than lamivudine alone for HBeAg-positive chronic outcomes in acute MI after failed thrombolytic therapy, 60-61 hepatitis B, 5 Review: Evidence supporting reduced death and reinfarction by Pioglitzaone percutaneous coronary intervention after thrombolysis is Pioglitazone did not reduce a composite endpoint of macrovascular inconclusive, 60-61 complications and increased risk for heart failure in type 2 Thrombophlebitis diabetes with macrovascular disease, 34 Vena cava filters reduced long-term risk for pulmonary embolism in Polyneuropathies proximal deep venous thrombosis, 18 Intensive insulin therapy reduced the incidence of neurologic Ticlopidine complications in critically ill patients, 20 Addition of clopidogrel to aspirin, but not early use of metoprolol, Postoperative complications improved overall outcome in acute myocardial infarction, 58-59 Review: Evidence of benefit for perioperative B-blockers in Clopidogrel before percutaneous coronary intervention reduced noncardiac surgery is unreliable, 17 cardiovascular outcome in ST-elevation myocardial infarction, 29 Prednisolone. Timolol Prednisolone plus a disease-modifying antirheumatic drug improved A nonselective B-blocker did not prevent gastroesophageal varices in outcomes in early rheumatoid arthritis, 73 cirrhosis and portal hypertension, 68 Protein C Tomography, x-ray computed Drotrecogin- (activated) did not reduce death and increased The Canadian CT Head Rule was as sensitive as, but more specific bleeding in patients with severe sepsis and low risk for death, 43 than, the New Orleans Criteria for identifying minor head injury, 53 Pulmonary disease, chronic obstructive Review: Cardioselective B-blockers do not produce adverse ‘Trimethoprim respiratory effects in COPD, 66 ‘Trimethoprim reduced dysuria in women with symptoms of urinary tract infection but negative urine dipstick test results, 1 Pulmonary embolism Vena cava filters reduced long-term risk for pulmonary embolism in proximal deep venous thrombosis, 18 Urinary tract infections R Trimethoprim reduced dysuria in women with symptoms of urinary Respiratory tract infections tract infection but negative urine dipstick test results, 1 A clinical decision support system reduced antimicrobial use for acute respiratory tract infections in rural settings, 81 V Resuscitation Vena cava filters Management with a pulmonary artery catheter did not reduce fena cava filters reduced long-term risk for pulmonary embolism in all-cause mortality in critically ill patients, 21 proximal deep venous thrombosis, 18 S Venous thrombosis Review: The Wells rule is more useful than individual clinical Saccharomyces features for predicting risk for deep venous thrombosis, 46-47 Review: Saccharomyces boulardii reduces risk for antibiotic-associated The Wells rule was not useful in ruling out deep venous thrombosis diarrhea, 45 in a primary care setting, 46-47 Sepsis Ventricular dysfunction, left Drotrecogin-O (activated) did not reduce death and increased Adjunctive treatment with eplerenone reduced 30-day all-cause bleeding in patients with severe sepsis and low risk for death, 43 mortality in acute myocardial infarction, 15 Skin neoplasms Vitamin D Family history and dysplastic nevi increased risk for multiple Review: Vitamin D plus calcium, but not vitamin D alone, prevents primary melanomas after an initial melanoma, 77 osteoporotic fractures in older persons, 14 92 ©ACP MAY/JUNE 2006 |V OLUME 144 * NUMBER 3 ACP JOURNAL CLUB

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