Cover Page: iii
List of Contributors Page: vii
Preface Page: ix
Acknowledgements Page: xi
CHAPTER 1: Introduction Page: 1
Introduction Page: 1
The significance of skin disease Page: 2
Descriptive terms of clinical inspection Page: 3
Clinical approach to the diagnosis of rashes Page: 5
Symmetry Page: 6
Diagnosis Page: 6
Distribution Page: 7
Morphology Page: 8
Assessment of the patient Page: 9
Further reading Page: 10
CHAPTER 2: Psoriasis Page: 11
Introduction Page: 11
Clinical appearance Page: 12
The typical patient Page: 13
Clinical presentation Page: 13
Psoriatic arthritis – pathophysiology Page: 16
Psoriatic arthritis – clinical presentation Page: 17
Psoriasis and systemic disease Page: 17
Further reading Page: 18
CHAPTER 3: Management of Psoriasis Page: 19
Introduction Page: 19
Dermatology day treatment units Page: 19
Topical treatment Page: 20
Scalp psoriasis Page: 21
Ultraviolet treatment – phototherapy and photochemotherapy Page: 21
Ultraviolet B (UVB) Page: 23
Ultraviolet A (UVA) Page: 23
Systemic treatment Page: 23
Methotrexate Page: 23
Acitretin Page: 24
Ciclosporin A Page: 24
Mycophenolate mofetil (MMF) Page: 24
Biological therapy Page: 25
Etanercept Page: 25
Infliximab Page: 25
Adalimumab Page: 26
Ustekinumab Page: 26
Ixekizumab Page: 26
Secukinumab Page: 26
Apremilast Page: 26
Further reading Page: 26
CHAPTER 4: Eczema (Dermatitis) Page: 27
Clinical features Page: 27
Pathophysiology Page: 27
Pathology Page: 27
Types of eczema Page: 28
Classification of eczema Page: 31
Clinical features Page: 31
Allergic contact dermatitis Page: 31
Irritant contact dermatitis Page: 32
Photodermatitis Page: 33
Occupational dermatitis Page: 34
Investigations of contact dermatitis Page: 35
Patch testing Page: 35
General management of eczema Page: 36
Biological treatment for atopic dermatitis Page: 37
Pruritus Page: 37
Pruritus with skin changes Page: 37
Pruritus with normal skin Page: 38
Management of pruritus Page: 38
Further reading Page: 38
CHAPTER 5: Urticaria and Angio‐oedema Page: 39
Introduction Page: 39
Pathophysiology Page: 39
Clinical history Page: 39
Classification of urticaria Page: 39
Ordinary urticaria Page: 40
Cholinergic urticaria Page: 41
Solar urticaria Page: 41
Pressure urticaria Page: 41
Angio‐oedema Page: 41
General investigations Page: 42
General management Page: 42
Further reading Page: 42
CHAPTER 6: Skin and Photosensitivity Page: 43
Ultraviolet radiation Page: 43
Skin pigmentation and fitzpatrick skin type Page: 43
Oculocutaneous albinism Page: 44
Xeroderma pigmentosum Page: 44
Medications causing photosensitivity Page: 46
Photosensitive disorders Page: 47
Vitamin D levels and sun protection Page: 48
Reference Page: 49
Further reading Page: 49
CHAPTER 7: Drug Rashes Page: 51
Introduction Page: 51
History Page: 51
Examination Page: 51
Investigation of a suspected drug reaction Page: 52
Classification of drug reactions in the skin Page: 52
Further reading Page: 58
CHAPTER 8: Immunobullous and Other Blistering Disorders Page: 59
Introduction Page: 59
Pathophysiology Page: 59
Differential diagnosis Page: 60
Clinical features of immunobullous disorders Page: 61
Investigation of immunobullous disease Page: 64
Management of immunobullous disease Page: 65
Further reading Page: 66
CHAPTER 9: Connective Tissue Disease, Vasculitis, and Related Disorders Page: 67
Introduction Page: 67
Connective tissue disease Page: 67
Vasculitis Page: 67
Polyarteritis nodosa (PAN) Page: 69
Henoch–schönlein purpura (IgA vasculitis) Page: 69
Management of cutaneous vasculitis Page: 69
Chilblains (perniosis) Page: 69
Raynaud's phenomenon Page: 70
Systemic sclerosis (SSc) Page: 70
Lichen planus (LP) Page: 71
Lupus erythematosus (LE) Page: 71
Dermatomyositis Page: 73
Mixed connective tissue disease (MCTD) Page: 74
Further reading Page: 74
CHAPTER 10: The Skin and Systemic Disease Page: 75
Introduction Page: 75
Skin reactions associated with infections Page: 75
Sarcoidosis Page: 77
Skin changes associated with hormonal imbalance Page: 77
Thyroid disease Page: 78
Skin changes associated with disorders of the gastrointestinal system and liver Page: 78
Liver disease and the skin Page: 81
Pigmentation disorders Page: 82
Skin manifestations of underlying malignancy Page: 83
Pregnancy and the skin Page: 84
Genetics and skin disease Page: 84
Single gene disorders Page: 85
Further reading Page: 86
CHAPTER 11: Leg Ulcers Page: 87
Introduction Page: 87
Venous ulcers Page: 88
Arterial ulcers Page: 91
Diabetic/neuropathic ulcers Page: 92
Inflammatory conditions Page: 92
Infectious ulcers Page: 92
Malignant diseases Page: 93
Trauma Page: 93
Further reading Page: 93
CHAPTER 12: Acne, Rosacea, and Hidradenitis Suppurativa Page: 95
Introduction Page: 95
What is acne? Page: 95
Underlying causes Page: 96
Diet Page: 97
Types of acne Page: 97
Treatment of acne Page: 99
Rosacea Page: 101
Management Page: 102
Further reading Page: 103
CHAPTER 13: Bacterial Infections Page: 105
Introduction Page: 105
Clinical presentation Page: 105
Bacterial investigations Page: 105
General approach to management Page: 107
Superficial infections Page: 107
Deeper infections Page: 108
Mycobacterial disease Page: 110
Other infections Page: 111
Further reading Page: 112
CHAPTER 14: Viral Infections Page: 113
Introduction Page: 113
Herpes viruses Page: 113
Treatment Page: 118
Viral diseases with rashes Page: 119
Further reading Page: 121
CHAPTER 15: HIV and the Skin Page: 123
Introduction Page: 123
Stages of HIV Page: 124
Skin disorders in HIV Page: 124
Infections Page: 125
Further reading Page: 129
CHAPTER 16: Fungal Infections Page: 131
Introduction Page: 131
Investigations Page: 131
General features of fungi in the skin Page: 132
Yeast infections Page: 136
Deep fungal infections Page: 137
Systemic antifungal drugs Page: 138
Further reading Page: 138
CHAPTER 17: Insect Bites and Infestations Page: 139
Insect bites and stings Page: 139
Delusions of parasitosis (DoP) Page: 140
Allergic reaction to bites Page: 140
Management of bite reactions Page: 141
Prevention of bites Page: 141
Insect bites transmitting parasites Page: 141
Lyme disease Page: 141
Spider bites Page: 141
Wasp and bee stings Page: 142
Treatment Page: 142
Infestations Page: 142
Cutaneous larva migrans Page: 145
Further reading Page: 145
CHAPTER 18: Tropical Dermatology Page: 147
Introduction Page: 147
Bacterial Infections Page: 147
Superficial fungal infections Page: 150
Deep fungal infections Page: 151
Infestations Page: 153
Further reading Page: 155
CHAPTER 19: Hair and Scalp Page: 157
Introduction Page: 157
The hair follicle and hair cycle Page: 157
Hair loss Page: 157
Non‐scarring alopecias Page: 158
Other non‐scarring alopecias Page: 160
Tinea capitis Page: 161
Scarring alopecias Page: 161
Excessive hair Page: 163
Skin disease involving the scalp Page: 164
Further reading Page: 164
CHAPTER 20: Diseases of the Nails Page: 165
Introduction Page: 165
Changes of shape, surface, and attachment Page: 165
Nail bed changes Page: 168
Nail plate changes Page: 168
Common dermatoses and the nail unit Page: 169
Infection Page: 171
Trauma Page: 171
General diseases affecting the nails Page: 172
Treatment of nail conditions Page: 173
Further reading Page: 174
CHAPTER 21: Genital Dermatoses Page: 175
Introduction Page: 175
History and examination Page: 175
Eczema Page: 176
Lichen simplex Page: 176
Balanitis and balano‐posthitis Page: 176
Psoriasis Page: 176
Lichen sclerosus Page: 177
Lichen planus Page: 178
Other inflammatory dermatoses Page: 179
Ulcers Page: 179
Pigmentation Page: 179
Infections Page: 180
Intra‐epithelial neoplasia Page: 180
Extra‐mammary paget’s disease Page: 181
Vulval and penile pain Page: 181
Further reading Page: 181
CHAPTER 22: Benign Skin Tumours Page: 183
Introduction Page: 183
Pigmented benign tumours Page: 184
Melanocytic naevi Page: 185
Dermatofibroma (benign fibrous histiocytoma) Page: 187
Benign vascular tumours Page: 188
Benign tumour papules Page: 189
Benign tumour nodules Page: 191
Benign tumour plaques Page: 192
Further reading Page: 193
CHAPTER 23: Premalignant and Malignant Skin Lesions Page: 195
Introduction Page: 195
Premalignant skin tumours Page: 195
Malignant skin tumours Page: 196
Moles/naevi: benign or malignant? Page: 199
Dysplastic naevi Page: 199
Melanoma Page: 200
Cutaneous lymphoma Page: 204
Other cutaneous malignancies Page: 205
Further reading Page: 205
CHAPTER 24: Practical Procedures and Skin Surgery Page: 207
Introduction Page: 207
Application technique Page: 207
Risks and precautions Page: 208
Skin lesions suitable for freezing Page: 208
Electrosurgery Page: 209
Curettage Page: 209
Diagnostic biopsies Page: 210
Incisional biopsy Page: 211
Surgical excision Page: 211
Mohs micrographic surgery Page: 214
Further reading Page: 214
CHAPTER 25: Lasers, Intense Pulsed Light, and Photodynamic Therapy Page: 215
Lasers in dermatology Page: 215
Lasers versus intense pulsed light Page: 215
Laser treatment Page: 215
Dermabrasion and chemical peels Page: 220
Intense pulsed light Page: 220
Photodynamic therapy Page: 220
Summary Page: 221
Further reading Page: 221
CHAPTER 26: Cosmetic Dermatology Page: 223
Beauty and visible ageing Page: 223
The preoperative assessment Page: 223
Soft tissue augmentation Page: 223
Botulinum toxins Page: 226
Chemical peels Page: 228
Skin tightening devices Page: 230
Further reading Page: 230
CHAPTER 27: Wounds, Dressings, and Bandages Page: 231
Introduction Page: 231
Wounds Page: 231
Dressings Page: 235
Bandages Page: 239
References Page: 243
Further reading Page: 243
CHAPTER 28: Formulary Page: 245
Introduction Page: 245
Topical therapy Page: 245
Emollients Page: 245
Topical immunomodulatory treatments Page: 245
Phototherapy Page: 249
Systemic therapy Page: 249
Biological therapies Page: 252
Miscellaneous Page: 253
Further reading Page: 253
Index Page: 255
End User License Agreement Page: 263
ABC of Dermatology SEVENTH EDITION
ABC of Dermatology is the bestselling, practical guide for anyone involved in clinical dermatology. This fully illustrated book helps readers identify, recognise, treat, and manage the common dermatological conditions encountered in daily practice.
The seventh edition has been revised and updated to incorporate current approaches to the management of skin disease, such as the use of new biological agents for treating inflammatory disease and tumours, and new chapters on cosmetic dermatology procedures, genital dermatology and cutting-edge advances in genetics and pathophysiology.
- Presents a practical approach to clinical dermatology that relates skin changes to specific skin conditions and underlying pathology
- Summarises relevant pathological processes, diagnostic features, learning points, and treatment options for a range of conditions
- Offers hundreds of full-colour clinical photographs that illustrate manifestations of skin disease in a multitude of diverse skin tones and ethnic groups
- Covers a wide range of skin management treatments, from simple interventions to sophisticated immunotherapies
- Includes insights on the increasing use of teledermatology by remote doctors
ABC of Dermatology is a must-have guide for GPs, junior doctors, medical students, and primary healthcare professionals.
