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ABC of cancer care PDF

102 Pages·2013·3.083 MB·English
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Cancer Care Cancer Care Carlo Palmieri BSc PhD FRCP UniversityofLiverpool TheRoyalLiverpoolUniversityHospital&TheClatterbridgeCancerCentre Liverpool,UK Esther Bird MA MRCP FRCR DFFP SilverdaleGPSurgery BurgessHill WestSussex,UK Richard Simcock MRCPI FRCR SussexCancerCentre BrightonandSussexUniversityHospitalsNHSTrust Brighton,UK A John Wiley & Sons, Ltd., Publication Thiseditionfirstpublished2013,2013byJohnWiley&Sons BMJBooksisanimprintofBMJPublishingGroupLimited,usedunderlicencebyBlackwellPublishingwhichwasacquiredbyJohnWiley &SonsinFebruary2007.Blackwell’spublishingprogrammehasbeenmergedwithWiley’sglobalScientific,TechnicalandMedical businesstoformWiley-Blackwell. Registeredoffice:JohnWiley&Sons,Ltd,TheAtrium,SouthernGate,Chichester,WestSussex,PO198SQ,UK Editorialoffices: 9600GarsingtonRoad,Oxford,OX42DQ,UK TheAtrium,SouthernGate,Chichester,WestSussex,PO198SQ,UK 111RiverStreet,Hoboken,NJ07030-5774,USA Fordetailsofourglobaleditorialoffices,forcustomerservicesandforinformationabouthowtoapplyforpermissiontoreusethe copyrightmaterialinthisbookpleaseseeourwebsiteatwww.wiley.com/wiley-blackwell. TherightoftheauthortobeidentifiedastheauthorofthisworkhasbeenassertedinaccordancewiththeUKCopyright,Designsand PatentsAct1988. Allrightsreserved.Nopartofthispublicationmaybereproduced,storedinaretrievalsystem,ortransmitted,inanyformorbyany means,electronic,mechanical,photocopying,recordingorotherwise,exceptaspermittedbytheUKCopyright,DesignsandPatentsAct 1988,withoutthepriorpermissionofthepublisher. Designationsusedbycompaniestodistinguishtheirproductsareoftenclaimedastrademarks.Allbrandnamesandproductnamesused inthisbookaretradenames,servicemarks,trademarksorregisteredtrademarksoftheirrespectiveowners.Thepublisherisnotassociated withanyproductorvendormentionedinthisbook.Itissoldontheunderstandingthatthepublisherisnotengagedinrendering professionalservices.Ifprofessionaladviceorotherexpertassistanceisrequired,theservicesofacompetentprofessionalshouldbesought. Thecontentsofthisworkareintendedtofurthergeneralscientificresearch,understanding,anddiscussiononlyandarenotintendedand shouldnotberelieduponasrecommendingorpromotingaspecificmethod,diagnosis,ortreatmentbyphysiciansforanyparticular patient.Thepublisherandtheauthormakenorepresentationsorwarrantieswithrespecttotheaccuracyorcompletenessofthecontents ofthisworkandspecificallydisclaimallwarranties,includingwithoutlimitationanyimpliedwarrantiesoffitnessforaparticularpurpose. Inviewofongoingresearch,equipmentmodifications,changesingovernmentalregulations,andtheconstantflowofinformationrelating totheuseofmedicines,equipment,anddevices,thereaderisurgedtoreviewandevaluatetheinformationprovidedinthepackageinsert orinstructionsforeachmedicine,equipment,ordevicefor,amongotherthings,anychangesintheinstructionsorindicationofusageand foraddedwarningsandprecautions.Readersshouldconsultwithaspecialistwhereappropriate.ThefactthatanorganizationorWebsite isreferredtointhisworkasacitationand/orapotentialsourceoffurtherinformationdoesnotmeanthattheauthororthepublisher endorsestheinformationtheorganizationorWebsitemayprovideorrecommendationsitmaymake.Further,readersshouldbeaware thatInternetWebsiteslistedinthisworkmayhavechangedordisappearedbetweenwhenthisworkwaswrittenandwhenitisread.No warrantymaybecreatedorextendedbyanypromotionalstatementsforthiswork.Neitherthepublishernortheauthorshallbeliablefor anydamagesarisingherefrom. LibraryofCongressCataloging-in-PublicationData ABCofcancercare/editedbyCarloPalmieri,EstherBird,RichardSimcock. p.;cm. Includesbibliographicalreferencesandindex. ISBN978-0-470-67440-6(pbk.) I.Palmieri,Carlo,1968–editorofcompilation.II.Bird,Esther,1970–editorofcompilation.III.Simcock,Richard,1969–editorof compilation. [DNLM:1.Neoplasms–therapy.2.Neoplasms–diagnosis.QZ266] RC261.A7 616.99’4–dc23 2013008892 AcataloguerecordforthisbookisavailablefromtheBritishLibrary. Wileyalsopublishesitsbooksinavarietyofelectronicformats.Somecontentthatappearsinprintmaynotbeavailableinelectronicbooks. CoverImageusedwithpermissionfromJamesLewis,ClinicalMediaCentre,BrightonandSussexUniversityHospitalsNHSTrust. Copyright2013,JamesLewis&BrightonandSussexUniversityHospitalsNHSTrust CoverdesignbyAndyMeanden Setin9.25/12MinionbyLaserwordsPrivateLimited,Chennai,India Printedin 1 2013 Contents ListofContributors,vii Preface,xi Acknowledgements,xiii 1 MultidisciplinaryCare,1 RichardSimcock 2 CancerImaging,5 GuyBurkillandAdrianK.P.Lim 3 Surgery,10 DanielRichardLeffandRichardSimcock 4 SurgeryforMetastaticDisease,15 TimothyW.R.Briggs,ElizabethJ.Gillott,LewisW.Thorne,andLongR.Jiao 5 Chemotherapy,20 CatherineHarper-WynneandCatherineM.Kelly 6 ToxicitiesofChemotherapy,26 SachaJonHowell,AlisonJones,andColinR.James 7 Radiotherapy,30 AlastairThomsonandMarkBeresford 8 ToxicitiesofRadiotherapy,34 RussellBurcombe,JonathanHicks,andRichardSimcock 9 EndocrineTherapy,39 CarloPalmieri,MatthewFlook,andDuncanC.Gilbert 10 BiologicalandTargetedTherapies,44 RuthE.Board,JenniferW.Pang,CarloPalmieri,andSuzyCleator 11 TrialsinCancerCare,50 EvandrodeAzambuja,DavidCameron,andJanetE.Brown 12 OncologicalEmergencies,55 ThomasE.Newsom-DavisandMohammedRizwanullah 13 CancerintheElderly,61 AlistairRingandJulietE.Wright 14 Nutrition,64 MhairiDonald 15 ComplementaryandAlternativeMedicineinCancerPatients,69 RichardSimcockandSarahCavilla v vi Contents 16 SpecialistNursingCare,74 ClareSullivan,BeverleyLonghurst,AmeliaCook,ElizabethBowman,andJeanRodell 17 CancerSurvivorship,78 EstherBird,AmyGuppy,andCarloPalmieri Index,83 List of Contributors Mark Beresford DM MA BM Bch MRCP FRCR David Cameron MD FRCP ConsultantClinicalOncologist&VisitingSeniorLecturer ProfessorofOncology RoyalUnitedHospital UniversityofEdinburgh Bath,UK Edinburgh,UK Esther Bird MA MRCP FRCR DFFP Sarah Cavilla SilverdaleGPSurgery SpecialistRegistrarinClinicalOncology BurgessHill SussexCancerCentre WestSussex,UK BrightonandSussexUniversityHospitalsNHSTrust Brighton,UK Ruth E. Board MBChB PhD Suzy Cleator BM BCh MRCP FRCR PhD ConsultantinMedicalOncology ConsultantClinicalOncologist&HonorarySeniorLecturer RosemereCancerCentre ImperialCollegeHealthcareNHSTrust RoyalPrestonHospital London,UK Preston,UK Amelia Cook Elizabeth Bowman BreastClinicalNurseSpecialist BreastClinicalNurseSpecialist TheHarleyStreetClinic(HCAInternational) TheHarleyStreetClinic(HCAInternational) London,UK London,UK Evandro de Azambuja MD PhD Timothy W.R. Briggs MD(Res) MCh(Orth) FRCS MedicalDirector ConsultantOrthopaedicSurgeon BrEASTDataCentre RoyalNationalOrthopaedicHospital JulesBordetInstitute Stanmore,UK Brussels,Belgium Janet E. Brown MD FRCP Mhairi Donald BSc RD SeniorClinicalLecturer&HonoraryConsultantinMedicalOncology MacmillanConsultantDietician UniversityofLeeds SussexCancerCentre StJames’sUniversityHospital BrightonandSussexUniversityHospitalsNHSTrust Leeds,UK Brighton,UK Russell Burcombe MB BS BSc Hons MD FRCP Matthew Flook MRCP FRCR SpecialistRegistrarinMedicalOncology ConsultantClinicalOncologist DepartmentofMedicalOncology KentOncologyCentre ImperialCollegeHealthcareNHSTrust MaidstoneHospital London,UK Maidstone,Kent,UK Duncan C. Gilbert MA MRCP FRCR PhD Guy Burkill BSc MB BS MA MRCP FRCR ConsultantClinicalOncologist&HonoraryClinicalSeniorLecturer ConsultantRadiologist SussexCancerCentre BrightonandSussexUniversityHospitalsNHSTrust BrightonandSussexUniversityHospitalsNHSTrust Brighton,UK Brighton,UK vii viii ListofContributors Elizabeth J. Gillott BMedSci MBBS MRCS Daniel Richard Leff MBBS PhD FRCS (Gen Surg) ResearchFellow CancerResearchUKAcademicClinicalLecturerinSurgery RoyalNationalOrthopaedicHospital DepartmentofSurgeryandCancer Stanmore,UK CancerResearchUKCentre ImperialCollegeLondon Amy Guppy MD MRCP London,UK ConsultantMedicalOncologist MountVernonCancerCentre&HillingdonHospitalsNHSFoundation Adrian K.P. Lim MD FRCR Trust ConsultantRadiologist&ReaderinRadiology Northwood,Herts,UK DepartmentofImaging Catherine Harper-Wynne MD FRCP ImperialCollegeHealthcareNHSTrust London,UK ConsultantMedicalOncologist KentOncologyCentre Beverley Longhurst MaidstoneHospital Barming,Kent,UK BreastClinicalNurseSpecialist TheHarleyStreetClinic(HCAInternational) Jonathan Hicks London,UK ConsultantClinicalOncologist BeatsonWestofScotlandCancerCentre Thomas E. Newsom-Davis BSc PhD MRCP Glasgow,UK ConsultantMedicalOncologist ChelseaandWestminsterHealthcareNHSFoundationTrust Sacha Jon Howell MRCP PhD London,UK SeniorLecturer&HonoraryConsultantinMedicalOncology UniversityofManchester,InstituteofCancerStudies Carlo Palmieri BSc PhD FRCP DepartmentofMedicalOncology ProfessorofTranslationalOncology&ConsultantMedicalOncologist TheChristieNHSFoundationTrust UniversityofLiverpool Manchester,UK DepartmentofMolecular&ClinicalCancerMedicine Colin R. James PhD MB BCH BAO MRCP TheRoyalLiverpoolUniversityHospital&TheClatterbridgeCancerCentre Liverpool,UK Consultant&HonorarySeniorLecturerinMedicalOncology BelfastHealthandSocialCareTrust Jennifer W. Pang BSc MB ChB DepartmentofOncology NorthernIrelandCancerCentre SpecialistRegistrarinClinicalOncology BelfastCityHospital ImperialCollegeHealthcareNHSTrust Belfast,UK London,UK Long R. Jiao MD FRCS Alistair Ring MA MD MRCP ReaderinSurgery SeniorLecturer&HonoraryConsultantinMedicalOncology ConsultantHepatobiliary&PancreaticSurgeon BrightonandSussexMedicalSchool DepartmentofSurgeryandCancer SussexCancerCentre ImperialCollegeLondon BrightonandSussexUniversityHospitalsNHSTrust London,UK Brighton,UK Alison Jones MD FRCP Mohammed Rizwanullah MRCP FRCR ConsultantMedicalOncologist ConsultantClinicalOncologist RoyalFreeHospitalandUniversityCollegeHospital BeatsonWestofScotlandCancerCentre London,UK Glasgow,UK Catherine M. Kelly MB BCh BAO BSc MSc MRCPI Jean Rodell ConsultantMedicalOncologist DepartmentofMedicalOncology BreastClinicalNurseSpecialist MaterMisericordiaeUniversityHospital TheHarleyStreetClinic(HCAInternational) Dublin,Ireland London,UK

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