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A DICTIONARY OF THE HISTORY OF MEDICINE A DICTIONARY OF THE HISTORY OF MEDICINE Anton Sebastian informa healthcare New York London First published in 1999 by the Parthenon Publishing Group. This edition published by Informa Healthcare, Telephone House, 69-77 Paul Street, London EC2A 4LQ, UK. Simultaneously published in the USA by Informa Healthcare, 52 Vanderbilt Avenue, 7th Floor, New York, NY 10017, USA. Informa Healthcare is a trading division of Informa UK Ltd. Registered Office: 37-41 Mortimer Street, London W1T 3JH, UK. Registered in England and Wales number 1072954. ©2011 Informa Healthcare, except as otherwise indicated No claim to original U.S. Government works Reprinted material is quoted with permission. Although every effort has been made to ensure that all owners of copyright material have been acknowledged in this publication, we would be glad to acknowledge in subsequent reprints or editions any omissions brought to our attention. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, unless with the prior written permission of the publisher or in accordance with the provisions of the Copyright, Designs and Patents Act 1988 or under the terms of any licence permitting limited copying issued by the Copyright Licensing Agency, 90 Tottenham Court Road, London W1P 0LP, UK, or the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA (http://www.copyright.com/ or telephone 978-750-8400). Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe. This book contains information from reputable sources and although reasonable efforts have been made to publish accurate information, the publisher makes no warranties (either express or implied) as to the accuracy or fitness for a particular purpose of the information or advice contained herein. The publisher wishes to make it clear that any views or opinions expressed in this book by individual authors or contributors are their personal views and opinions and do not necessarily reflect the views/opinions of the publisher. Any information or guidance contained in this book is intended for use solely by medical professionals strictly as a supplement to the medical professional's own judgement, knowledge of the patient's medical history, relevant manufacturer's instructions and the appropriate best practice guidelines. Because of the rapid advances in medical science, any information or advice on dosages, procedures, or diagnoses should be independently verified. This book does not indicate whether a particular treatment is appropriate or suitable for a particular individual. Ultimately it is the sole responsibility of the medical professional to make his or her own professional judgements, so as appropriately to advise and treat patients. Save for death or personal injury caused by the publisher's negligence and to the fullest extent otherwise permitted by law, neither the publisher nor any person engaged or employed by the publisher shall be responsible or liable for any loss, injury or damage caused to any person or property arising in any way from the use of this book. A CIP record for this book is available from the British Library. Library of Congress Cataloging-in-Publication Data available on application ISBN-13: 9781850700210 Orders may be sent to: Informa Healthcare, Sheepen Place, Colchester, Essex CO3 3LP, UK Telephone: +44 (0)20 7017 5540 Email: [email protected] Website: http://informahealthcarebooks.com/ For corporate sales please contact: [email protected] For foreign rights please contact: [email protected] For reprint permissions please contact: [email protected] Preface The idea of this book came to me nearly ten years ago treatment of disease. Hippocrates around 400 BC when I started cataloging my antiquarian and rare dispelled the myths of medicine and started treating it medical and science books for my personal library of as a science. Around this same period, contemporary 3000 volumes. The vast amount of material available for Ayurvedic medicine in India and Chinese medicine in the reference on the history of medicine only confused the East were developed independently. The Romans accept­ issue. Often I had to spend a lot of time looking through ed medicine as a respectable profession around 100 BC. several books before I obtained any specific information The Arabs, around 750 AD, translated and modified Greek on a subject. As I went on I became more and more medicine and adapted it to suit their religion and climate convinced about the need for a single book that could and their influence lasted until the end of the Middle give specific information on any topic in history of Ages. During the 15th century in Europe Paracelsus medicine, as the Oxford Dictionary is to the English developed the art of alchemy into chemotherapeutics. language. I wanted this book to serve medical The French surgeon Ambroise Paré revolutionized researchers, presenters and clinicians who could not surgery in the next century. William Harvey announced afford to spend their valuable hours in the library look­ his discovery of blood circulation in the early 17th cen­ ing for specific historic information on their topics. I also tury. Several other important discoveries and rapid intended the book to be of interest to laymen, progress were made in the next few centuries. Most paramedics, medical students and anyone else concerned modern scientific principles and concepts were estab­ in anyway with health care. lished in the 19th and 20th centuries. The atomist The task of producing such a book I knew was theory of the universe proposed by Democritus over formidable as I realized that the story of medicine is in 2000 years ago was revived on a scientific basis by Ernest essence a recapitulation of mans attempts at survival Rutherford. Gregor Mendel’s work was revived by since his first appearance on Earth. This brought a William Bateson, establishing genetics as a separate prehistoric element into my book. In order to survive, science. The birth of modern physics gave explanation to early man had to hunt and gather, and for this he had to electricity, heat, light, sound and magnetism which were be fit and healthy, which led to the concept of health and previously observed as natural magic. Geology unfolded disease. The study of paleopathology has shown that the origin and development of Earth and its life forms. disease affected the hunter and hunted alike, leaving tell­ The relatively new «sciences such as anthropology tale marks in the skeletons of dinosaurs and prehistoric contributed to evolution theory and paleopathology man. The beginnings of medicine probably started with established the antiquity of diseases. Archeology hunting and gathering. During the pursuit of his prey, unearthed the evidence of ancient cultures and early man had the opportunity to study its locomotion, knowledge. These are only a few examples of the and he learned of the fatality of wounds and signs of progress that occurred. death when he killed for food. He unintentionally began Modern inventions and improved travel brought cures his dissections when he cut up his game for food. A cave as well as diseases. The miracle cure for malaria, cinchona painting of a mammoth drawn by Cro-Magnon man and bark, was brought from Peru to Spain from where it estimated to be over 39,000 years old reveals that he reached the rest of Europe in the early 17th century. Sea knew the position of the heart in the animal. travel spread the bubonic plague and the discovery of the The study of normal and morbid human anatomy New World may have brought syphilis to Europe. probably began with the practice of embalming by the Epidemics became pandemics causing a domino effect Egyptians, who excelled in medicine for nearly 3000 on lives. Industries brought occupational disease, years until overtaken by the Greeks around 600 BC. pollution and overcrowding. Airplanes removed the The Greek temples of Aesculapius built around this remaining barriers to disease, and cars introduced health time were probably the first inpatient institutions for problems resulting from road accidents, pollution, road rage and lack of exercise. With man s achievement of large share of the pooled funds. I believe that an histori­ ample production of food and comfortable living, cal understanding of the genesis of these factors will help diseases such as atherosclerosis, hypertension and diabetes us understand the complexity of our profession. became common in affluent society. On the other hand, Throughout the preparation of this book over the past with division of wealth came the diseases of deficiency ten years I had to keep reminding myself that it is a and famine. dictionary of the history of medicine, and not a Apart from the fact that medical history makes dictionary of medicine. In doing so I have minimised the interesting reading why should we study it, especially in use and explanation of technical language and definitions this era of high technology and specialization? In not which otherwise could be found in hundreds of available doing so we are in danger of losing the wisdom that has medical dictionaries. The portraits used in this book been handed down to us since the time of Aristotle. We emphasize those leaders of medicine as human beings may also lose the sense of medical ethics proposed by and not just names. The other illustrations, mostly taken Hippocrates. We may fail to realize how contemporary from my library, are for the readers to relate to the gurus failed great men like Mendel, Semmelweiss and subject more effectively. Henry Hickman in the past. Most of all, we may lose the I have used over 5000 volumes and hundreds of jour­ sense of gratitude to our predecessors, lose ourselves in nals as sources of primary and secondary references. our own achievements and fail to learn from the past. Although I have endeavored to cover every aspect The pride and glory of medicine enjoyed by doctors through over 10,000 key entries covering more than a today belongs in essence to those men of the past such as dozen specialties, my book can never do full justice to Hippocrates, Galen, Celsus, Harvey, Vesalius, Malpighi, the subject of the history of medicine because it is vast Bernard, Pasteur, Lister, and others whose discoveries and almost endless. An element of judgment has been have stood the test of time. They laid the framework used in the selection. HopefuUy, future editions will upon which others have worked to make medicine a benefit from and incorporate readers comments. marvel of today. In the present world of specialization In summary, I must thank my colleagues at the where we know more and more about less, we are in Berkshire and Battle Hospitals who took part in the danger of inteUectuaUy isolating ourselves from the audit of my work during the early stages seven years ago. knowledge of other walks of life. Today, politics controls I am indebted to David G.T. Bloomer, the Managing medical policies and threatens medical ethics. Market Director of Parthenon Publishing who painstakingly forces undermine our efforts to curb tobacco smoking guided his skilled team over the past year to bring my and pollution. Disintegration of social and family units book to publication. A big thank you to the Parthenon compound the problems of drug and alcohol addiction. editor for her meticulous scrutiny of my work and Pollution by industries and cars increases the incidence skillful editing. I am also grateful to the graphics team of chest diseases. Mass media such as television and radio for assembly and reproduction of the illustrations mold people s concepts of health and disease. Ready Last but not least I dedicate this book to my wife access to computers and faxes may undermine patient Vasanthi and my two children, Chuchi and Kevin, whose confidentiality. Genetic engineering has also produced time with me over the past decade I stole to complete several ethical dilemmas. Specialized surgery, such as this monumental task. cardiac transplant, saves relatively few lives but take a Anton Sebastian April 1999 Anton Sebastian MBBS MRCP is a consultant physician in general medicine with a life-long interest in the history of medicine and related sciences. He has developed one of the finest private collections of antiquarian books in these fields, currently totalling over 3000 volumes, including many original editions dating from the early sixteenth century onwards. Following the completion of his postgraduate training at the Charing Cross Hospital, London and Kingston Hospital, Surrey, he has held a number of appointments both in Great Britain and overseas. He is currently a consultant physician at the Victoria Infirmary, Glasgow. VI Dictionary of the History of Medicine ABBOTT 377 BC), Galen (AD 129-200), Paul ofAegina (625-690), Ptolemy and Euclid through turbulent times in history. A According to the Fihrist (Index of Sciences), compiled in AD 987, ten of Hippocrates’ works were translated by Hunayan ibn Ishaq or Johannitus (809—873) and his pupil Isa ibnYahya and the 16 books of Galen were translated by Hunayan and his pupil, Hubaysh ibn el-Hassan, who was also his nephew. Abbe, Ernest (1840—1905) A German physicist from Aaron of Alexandria Jewish physician and presbyter in the Eisenach who became professor at the university of Jena in yth century, who is supposed to have written 30 books on 1870 before he was made director of the Astronomical and medicine in Syrian, many now lost. Most of his remaining meteorological Institute in 1878. He was partner at the works compiled, from Greek, were called the Pandects of optical company of Carl Zeiss (1816—1888) who first Aaron and were translated into Arabic by the Syrian Jew, brought the improved microscope to the market. Abbe Maseijawaihi, in AD 683. Some of Aaron’s work was cited modernised the microscope by adding the apochromatic by the Arabian physician, Rhazes (850—932) who men­ objective, and the oil immersion method (first suggested by tioned Aaron as one of the first to describe smallpox and John Ware Stephenson) in 1878. He also introduced the measles, which were brought into Egypt following the con­ sub-stage condenser in 1886. At the death of his partner Carl quest by the Arabians in AD 640.The first three chapters of Zeiss in 1888, Abbe became the owner of the optical works. the first tract in Haly Abbas (930-994) famous book He improved the technique of phase contrast microscopy in Al-Kitabul-Maliki also contains some discussions on the 1892. writings of Aaron along with those of Hippocrates Abbe technique See Abbe, Robert. (460—377 BC), Galen (AD 129—200), Oribasius (325—403) and Paul ofAegina (625-690). Abbe, Robert (1851-1928) Surgeon from New York, USA who introduced the use of catgut for suturing the intestines Abactus [Latin: abigere, to drive out] Term used by Roman in 1889. He also devised the method of dilating the physicians for miscarriage. esophageal stricture in a retrograde fashion by opening the Abadie sign Spasm of levator palpebrae muscle of the eye as stomach to receive a ‘string saw’ from the buccal end and a sign in exophthalmic goiter, described at Paris, France in cutting the remaining tissue that contributed to the 1877 by Charles A. Abadie (1842-1932), ophthalmologist. stricture. The Abbe technique was named after him. Abaptiston or Ababtista [Greek: a, negative + babtiston, to sink under] Ancient surgical instrument in the form of a circular saw described by Galen (129—200), Fabricius ab Aquapendente (1537-1619) and Johann Schultes (1595- 1645). It was used to trephine the cranium. An earlier form of the instrument was cone-shaped so as to prevent the instrument sinking into the dura mater, hence its name. Abbasides Second line of rulers and descendants of Abul Abbas, the first Saracen Caliph of the Eastern Caliphate of Baghdad, from AD 750—1250. Abul Abbas on his accession transferred the Caliphate to Baghdad which became a great city of science and literature. At one time it had 860 Abbe technique for division of esophageal stricture. Hochberg, LA, 1960, licensed physicians with numerous hospitals.The dynasty of Thoracic Surgery before the 20th Century. Courtesy of Vantage Press, Abbasides included Harun-Al-Rashid,Al-Mansur and Al- New York Mamun (AD 813-833) who encouraged the collection and translation of Greek and Roman medical classics into Abbott Laboratories See Abbott, Wallace Calvin. Arabic. Their efforts, especially those of Almamon or Al- Mamun, the son of Caliph Harun-Al-Rashid, resulted in Abbott, Alexander Crever (1860-1935) Bacteriologist from the preservation of the earlier works of Hippocrates (460— Philadelphia, USA who designed a process for detecting ABBOTT Dictionary of the History of Medicine spores in bacteria with the help of methylene blue and vascular insufficiency was first described by fuchsin. J. Schnitzler in 1901. Abbott, Edville Gerhardt (1871-1938) Orthopedic surgeon Abdominal hernia [Latin: abdomen, heUy + hernia, rupture] from Portland, Maine, USA who designed a treatment for Protrusion of a structure through an opening in the abdom­ scoliosis using bandages and a frame, followed by a series of inal wall. One of the first monographs on abdominal hernia plasterjackets. was written by Thomas PridginTeale (1801—1868) of Leeds, UK in 1846. The Ball operation for the radical cure of Abbott, Maude Elizabeth Seymour (1869-1940) Canadian abdominal hernia was described in 1887 by Charles Bent pioneer in the field of pediatric cardiology She published Ball (1851-1916), surgeon and proctologist from Dublin, the results of a study into congenital heart disease that Ireland. showed that it was associated with an 18% risk of other mal­ formations. Soon after the death of Sir William Osier Abdominal hysterectomy See hysterectomy. (1849—1919) in 1919, Abbott published a memorial volume Abdominal injuries [Latin: abdomen, heUy; French: in, neg­ to his work. She is also famous for her promotion of medical ative +jus (jur-), right] Henri de Mondeville (1260—1320),a education for women in Canada. surgeon to King Philip-le-Bel of France, was one of the first Abbott, Wallace Calvin (1857—1921) Founder of the Abbott to write on abdominal injuries r.1306. In his treatise he Laboratories. Born into poverty in Vermont, USA, Abbott advised that if the large intestines were wounded they was able to fulfill his ambition of going to medical school should be sutured ‘as ferriers sew a skin’.The explorer and only at the age of 22. After obtaining his medical degree doctor, David Livingstone (1813-1873), in his experience from Michigan University in 1885 he borrowed a small sum during his African travels, described the successful surgical of money from a friend and startedThe People s Drug Store treatment of extruded abdominal viscera due to injury by in Ravenswood. He sold his own preparations, such as placing a gourd shell or calabash and sewing it to the toothache powders, laxatives and cold remedies and in abdominal wall. Many of the patients treated in this manner the early 1900s introduced a sugar-coating technique for were observed to do well and return to their normal life. tablets. His company later expanded to become the Abbott The repair of abdominal injuries has also been described by Alkaloidal Company and by 1930 it had grown into the the ancient Hindus, who excelled in surgery.The works of pharmaceutical giant, Abbott Laboratories. the Hindu Brahmin Susruta, written r. AD 500, amongst its hundreds of surgical procedures, describes the surgical Abderhalden, Emil (1877—1950) Pupil of Emil Fischer treatment of protrusion of intestines. Abdominal injuries (1852—1919) and professor of physiology at the University became a focus of interest owing to their common occur­ of Halle, Germany. He completed a bibliography of rence during the wars in the preceding three centuries. Sir alcoholism in 1897 and was the first to describe familial Cuthbert Wallace’s Abdominal Wounds (1918) is considered cystinosis in 1903. He edited the series Handbuch der biologischenArbeitsmethoden, 1920—1939. to be a classic on the subject and his Surgery of the Abdominal Wounds (1922) is a treasure store of historical information. Abderhalden-Fanconi Syndrome or Familial cystinosis Another important book. Abdominal Injuries of Warfare, was was first described by Emil Abderhalden (1877—1950) in published by G. Gorden-Taylor in 1939. 1903 .The occurrence of glycosuria and phosphaturia in the Abdominal pregnancy See ectopic pregnancy. condition was described by Guido Fanconi (1892—1979) in 1936. See cystinosis, Fanconi syndrome. Abdominal surgery [Latin: chirurgia; Greek: cheir, hand + Abdominal [Latin: aWomew, belly]. ergon, work] The era of modern abdominal surgery started in the 19th century.The first splenectomy was performed by Abdominal aneurysm [Latin: abdomen,heUy; Greek: aneurys- Carl Friedrich Quittenbaum (1793—1852) of Germany in ma, a dilatation; French: eurys, wide] A sac formed by the 1826, but his patient died of shock within six hours.The first dilatation of the wall of the abdominal aorta. The first suc­ splenectomy in England was performed by Sir Thomas cessful resection of an abdominal aneurysm and repair with Spencer Wells (1818-1897) in 1865 and his patient lived for 6 a homologous graft was performed by Charles Dubost days. The first successful long-term result of the procedure (b 1914) of Par is, France in 1948. See aortic aneurysm. was achieved by Jules Emile Pean (1830—1898) of Paris, Abdominal angina [Latin: abdomen, belly + angere, to stran­ France in 1867. One of the first successful abdominal opera­ gle] A form of spasmodic abdominal pain due to mesenteric tions for intussusception was performed by Sir Jonathan Dictionary of the History of Medicine ABERCROMBIE Hutchinson (1828—1913) while he was at London Hospital Abel Method The first chemical extraction of the active in 1874. The first resection of the stomach for carcinoma principle of the suprarenal gland, performed by John Jacob was performed by Pean in 1879, but his operation was not Abel (1857-1938) of Johns Hopkins Medical School in successful. The first successful gastric resection was per­ 1898. He gave the name epinephrine to this extract which is formed by Theodor Billroth (1829—1894) in 1881. Phineas known as adrenaline in Britain. Sanborn Conner of Cincinnati, USA did a complete resec­ Abel, Frederick Gottfried (1714—1794) Physician and poet tion of the stomach in 1884 but his operation was also from Halberstadt, Germany who took his medical degree at unsuccessful. Carl Bernhard Schlatter (1864-1934), a Swiss Königsberg. He published a German translation of Juvenal surgeon, performed the first successful total gastrectomy for in 1788. carcinoma of the stomach in 1897. A procedure of partial Abel, John Jacob (1857-1938) Biochemist born in gastrectomy for carcinoma of the pyloric end of the stom­ Cleveland, Ohio, USA who graduated from the University ach was devised by William James Mayo (1861—1939) iii of Michigan. After obtaining his PhD from the same uni­ 1900. Polya operation, which is a modification of Billroth versity in 1883 he went to Europe where he spent 7 years operation II, was performed in 1911 by a Hungarian sur­ studying under the foremost scientists in Austria and geon, Jeno Eugene Alexander Polya (1876-1944). His Germany. He returned to America in 1891 and became pro­ operation involved gastrectomy combined with side-to- fessor of therapeutics at Michigan. Aged 36 years he was side anastomosis of the gastric remnant and the duodenum. appointed as the first professor of pharmacology at Johns Pólya is supposed to have been killed by Nazis, although his Hopkins University. His notable contributions to medicine body was never recovered. include: construction of the first membrane for artificial Abdominocentesis [Latin: ahdomino- ; Greek: kentesis, kidneys; first extraction of epinephrine (adrenaline), poste­ puncture] See paracentesis abdominis. rior pituitary hormones, hirudin and specific amino acids from the blood; and the first determination of the molecu­ Abdominoperineal resection [Latin from Greek: perineon, lar weight of cholesterol. He was also the first to obtain a perinaion] Combined abdominoperineal resection for carci­ crystalline form of insulin, in 1926. noma of the rectum was introduced by WiUiam Ernest Miles Abella A woman surgeon of the Middle Ages from the (1869-1947) in 1908. (syn. Miles resection). See Miles operation. School of Salerno, Italy during the reign of Charles of Abducent nerve [Latin: ab, away from + ducere, to lead] Anjou around AD 1059. She wrote several medical treatises (Syn. nervus abducens) The sixth cranial nerve, deriving its including Treatise deAtra Bili and De Natura Seminis Hominis. name from its relationship to the abductoris oculi or lateral Abengnefil or Aben-Guefit (997-1075) Arabian physician. rectus muscle. It was first described by Bartolommeo He wrote a medical treatise which was translated under the Eustachio (1524-1574), Italian anatomist. title De Virtuitibus Medicinarum et Ciborum and printed at Abdul-Latif or Abu Mohammed Abdul Latiff ibnjusuf (AD Venice, Italy in 1581. 1161—1231) Arabian scientist and traveler in Egypt during Aberavon Skull In 1910 Arnalt Jones presented the frontal the time of Saladin (1137-1193), the Sultan of Egypt and part of a skull belonging to the Neolithic Period, or later Syria. He taught medicine at Damascus, Aleppo and Egypt Stone Age, found at Aberavon, south Wales, to the Museum and has been credited with 166 treatises, some of which are of the Royal College of Surgeons in London, UK.This and on medical topics. He also studied human osteology and a similar skull found in the same region earlier in 1840, pro­ found that many of Galen’s (129—200) writings on the sub­ vided additional evidence for the presence of Neolithic ject were inaccurate. During his stay in Egypt he wrote a man in England. See skull. comprehensive account of the country’s flora and fauna. Abercrombie, John (1780—1844) Born in Aberdeen, Scot­ Abegg, Richard (1869-1910) Chemist from Danzig, Ger­ land, he graduated in medicine from Edinburgh University. many. One of the first to realize the chemical significance of He had a successful practice in Edinburgh and became sur­ electrons. In 1897 he proposed that the outer electron shell geon to the Royal Public Dispensary in 1805. He published governed the chemical properties of the atom. He also did Observations on the Diseases of the Spinal Marrow (1818), important work on osmotic pressures and freezing point of Pathological and Practical Researches on Diseases of the Brain and dilute solutions. Abegg died in a ballooning accident at Spinal Cord (1828), the first book on neuropathology and Koszalin, Poland. several other important medical works.

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