2017 Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor

23 Pages·2017·3.03 MB·English

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Crystal structure of mouse CEACAM1b

Structural and Molecular Evidence Suggesting Coronavirus-Driven Evolution of Mouse Receptor

Guiqing Peng 1, 2, #, Yang Yang 1, #, Joseph R. Pasquarella 1, Liqing Xu 1, 3, Zhaohui Qian 4,5,
Kathryn V. Holmes 5, and Fang Li 1, *

From
1 Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN
55455, USA
2 State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong
Agricultural University, Wuhan 430070, Hubei China
3Key Laboratory of Horticultural Plant Biology, Huazhong Agricultural University, Wuhan 4300
70, Hubei, China
4 MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese
Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
5 Department of Immunology and Microbiology, University of Colorado School of Medicine,
Aurora, CO 80045, USA

# These authors contributed equally to this work.

To whom correspondence should be addressed: Fang Li, Department of Pharmacology,
University of Minnesota Medical School, Minneapolis, MN 55455, Telephone: [phone];
Fax: [phone]; Email: