2016 Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

26 Pages·2016·4.24 MB·English

RESEARCH ARTICLE
Middle East Respiratory Coronavirus
Accessory Protein 4a Inhibits PKR-Mediated
Antiviral Stress Responses

Huib H. Rabouw1, Martijn A. Langereis1☯, Robert C. M. Knaap2☯, Tim J. Dalebout2,
Javier Canton3, Isabel Sola3, Luis Enjuanes3, Peter J. Bredenbeek2, Marjolein Kikkert2,
Raoul J. de Groot1, Frank J. M. van Kuppeveld1*

1 Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine,
Utrecht University, Utrecht, The Netherlands, 2 Molecular Virology Laboratory, Department of Medical
Microbiology, Leiden University Medical Center, Leiden, The Netherlands, 3 Department of Molecular and
Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autonoma de Madrid,
Madrid, Spain

☯ These authors contributed equally to this work.
*