2015 Structure-based virtual screening and experimental validations for discovery of inhibitors targeted towards the hum PDF
Preview 2015 Structure-based virtual screening and experimental validations for discovery of inhibitors targeted towards the hum
This is an Accepted Manuscript, which has been through the Royal Society of Chemistry peer review process and has been accepted for publication. Accepted Manuscripts are published online shortly after acceptance, before technical editing, formatting and proof reading. Using this free service, authors can make their results available to the community, in citable form, before we publish the edited article. We will replace this Accepted Manuscript with the edited and formatted Advance Article as soon as it is available. You can find more information about Accepted Manuscripts in the Information for Authors. Please note that technical editing may introduce minor changes to the text and/or graphics, which may alter content. The journal’s standard Terms & Conditions and the Ethical guidelines still apply. In no event shall the Royal Society of Chemistry be held responsible for any errors or omissions in this Accepted Manuscript or any consequences arising from the use of any information it contains. Accepted Manuscript Molecular BioSystems www.rsc.org/molecularbiosystems View Article Online View Journal This article can be cited before page numbers have been issued, to do this please use: C. Chang, S. Jeyachandran, N. Hu, C. Liu, S. Lin, Y. Wang, Y. Chang and M. Hou, Mol. BioSyst., 2015, DOI: 10.1039/C5MB00582E. Structure-based virtual screening and experimental validations for discovery of inhibitors targeted towards the human coronavirus nucleocapsid protein Graphical Abstract Page 1 of 26 Molecular BioSystems Molecular BioSystems Accepted Manuscript Published on 20 October 2015. Downloaded by University of California - Santa Barbara on 23/10/2015 14:17:43. View Article Online DOI: 10.1039/C5MB00582E 1 Structure-based virtual screening and experimental validations for discovery of inhibitors targeted towards the human coronavirus nucleocapsid protein Chung-ke Chang1§, Sivakamavalli Jeyachandran2§, Nien-Jen Hu3§, Chia-Ling Liu2§, Shing-Yen Lin2, Yong-Sheng Wang2, Yu-Ming Chang4, and Ming-Hon Hou2,3* 1Institute of Biomedical Science, Academia Sinica, Nangang, Taipei, Taiwan 2Institute of Genomics and Bioinformatics and Institute of Life Sciences, National Chung Hsing University, Taichung 40254, Taiwan 3Institute of Biochemistry, National Chung Hsing University, Taichung 40254, Taiwan 4Institute of Biological Chemistry, Academia Sinica, Taipei 11529, Taiwan §These authors contributed equally to this work. Corresponding Authors: *Author to whom correspondence should be addressed; E-Mail:
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