Article Potential Broad Spectrum Inhibitors of the Coronavirus 3CLpro: A Virtual Screening and Structure-Based Drug Design Study Michael Berry 1,2, Burtram C. Fielding 2,* and Junaid Gamieldien 1 Received: 1 July 2015; Accepted: 30 November 2015; Published: 15 December 2015 Academic Editor: Viktor Müller 1 South African Medical Research Council Bioinformatics Capacity Development Unit, South African National Bioinformatics Institute, University of the Western Cape, Bellville 7535, South Africa;