2015 MDA5 is critical to host defense during infection with murine coronavirus

40 Pages·2015·2.53 MB·English

MDA5 is critical to host defense during infection with
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murine coronavirus
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Zachary B. Zalinger, Ruth Elliott, Kristine M. Rose*
, and Susan R. Weiss#
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Department of Microbiology, Perelman School of Medicine, University of Pennsylvania,

Philadelphia, PA 19104-6076

Running title: MDA5 restricts MHV spread and pathogenesis

Key words: Murine coronavirus, MHV-induced hepatitis, MDA5 signaling

*Present address:
PATH
455 Massachusettes Ave, NW, suite 1000
Washington, DC 20001

#Corresponding author:
Susan R. Weiss
Department of Microbiology
University of Pennsylvania
Perelman School of Medicine
203A Johnson Pavilion
36th Street and Hamilton Walk
Philadelphia, PA 19104-6076
Phone: [phone]
Email: