2015 Discovery of a Novel Coronavirus, China Rattus Coronavirus HKU24, from Norway Rats Supports the Murine Origin of Be

56 Pages·2015·5.46 MB·English

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JVI02420-14R1 second revision
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Discovery of a novel coronavirus, China Rattus coronavirus HKU24, from Norway
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rats supports murine origin of Betacoronavirus 1 with implications on the ancestor
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of Betacoronavirus lineage A
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Susanna K. P. Lau,a,b,c,d† Patrick C. Y. Woo,a,b,c,d† Kenneth S. M. Li,d† Alan K. L. Tsang,d Rachel
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Y. Y. Fan,d Hayes K. H. Luk,d Jian-Piao Cai,d Kwok-Hung Chan,d Bo-Jian Zheng,a,b,c,d Ming
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Wang,e Kwok-Yung Yuena,b,c,d*
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State Key Laboratory of Emerging Infectious Diseases,a Research Centre of Infection and
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Immunology,b Carol Yu Centre for Infection,c Department of Microbiology,d The University of
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Hong Kong, Hong Kong; Guangzhou Center for Disease Control and Prevention, Guangzhou;e
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China
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Running title: China Rattus coronavirus HKU24
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†These authors contributed the same to the manuscript.
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*Corresponding author. Mailing address: State Key Laboratory of Emerging Infectious
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Diseases, Department of Microbiology, The University of Hong Kong, University Pathology
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Building, Queen Mary Hospital, Hong Kong. Phone: [phone]. Fax: [phone]. E-
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mail: