Dept of Anaesthesia, RUH Outputs 2015-2016 2015-16 2014-15 Grant awards 6 (approx. £5.4 million) not captured Papers 53 (and 13 in progress) 42 Editorials 18 14 Reviews 6 4 Correspondence 36 35 Posters 40 21 Books 3 (and 2 in progress) 5 Chapters 20 27 Presentations 99 82 Awards and prizes 22 13 Who was involved? Trainees 45 56 Consultants + CRRG 17 + 0 20 + 1 1 Research Grants 2015-16 Looslely A, Cook TM. £11,684.85 [NIAA/AAGBI] Satisfaction and Wellbeing in Anaesthetic Training (SWeAT) 2016 (Co-applicant with Dr Alex Loosley) Foy K. £2800 AAGBI International Relations Council Grant –Research in Zambia. Nolan JP. Co-applicant for NIHR Programme Development Grant (RP-DG-0612-10004) Improving Outcomes from Out of Hospital Cardiac Arrest: The Cardiac Arrest Individual Registry and Outcomes (CAIRO) Programme. 2013 – 2015 Chief Investigator Prof. Jonathan Benger, University Hospitals Bristol NHS Foundation Trust. £99,979.00 Nolan JP. Co-applicant for NIHR Health Service and Delivery Research Programme Grant (HS&DR – 12/178/18) Avoidable mortality from in-hospital cardiac arrest: Have interventions aimed at recognising and rescuing deteriorating patients made an impact on incidence and outcomes? 2014 – 2016 Chief Investigator Dr Helen Hogan, London School of Hygiene & Tropical Medicine £383,865. Nolan JP. Co-applicant for NIHR Health Technology Assessment Programme Grant (HTA - 12/127/126) for a randomised placebo controlled trial of adrenaline for out of hospital cardiac arrest. Chief Investigator Prof. Gavin D Perkins, University of Warwick. 2014 – 2019 £2,724,486.00 Nolan JP. Co-applicant for NIHR Health Technology Assessment Programme Grant (HTA-12/167/102) for a randomised trial of the effectiveness of a supra-glottic airway device versus tracheal intubation in the initial airway management of out of hospital cardiac arrest (AIRWAYS-2). Chief Investigator Prof. Jonathan Benger, University Hospitals Bristol NHS Foundation Trust. 2014 – 2018 £2,099,812 Cook TM. £170,000 Funding of National audit projects (internal funding) NAP6 £160,000 [£30,000 to the Aware Collaboration from Wellcome as part of the NAP5 project. (Applicants JJ Pandit and A Morley) TM Cook Led for wider project] 2 Prizes and Awards2015-2016 1. ‘Neuron specific enolase (NSE) analysis for neuroprognostication following out of hospital cardiac arrest (OHCA): implementation and initial results from a district general hospital’ Gosling M, Ray A, Nolan JP. President’s Prize for Oral presentation, Society of Intensive care of the West of England Feb 2017 2. Peri-operative management of the obese patient. A regional review of AAGBI guideline compliance. Foy K, Hardy R. AAGBI Winter Scientific Meeting, London, January 2017. Silver medal in group. 3. ‘BUNS screening’ in pneumonia in ICU. Mulcahy K, Sharvill R. Best presentation. South of Devon Intensive Care meting trainee prize June 2016 4. FONA and human factors. Cooper R. Best presentation– Society of Intensive Care of the West of England Feb 2016 5. Right patient, wrong operation - reviewing the indication for surgery can be an important component of the anaesthetic assessment. Bower J. AAGBI WSM Dec 2016. 2nd Best case report poster. 6. C-Mac Videolaryngoscopy - the anaesthetic assistant's view. Jones L, Mulcahy K, Fox J, Kelly FE, Cook TM. (Presented by Lydia jones DAS November 2016, Torbay). Wild card 2nd prize. 7. Two local produced short films to improve satisfaction with paediatric anaesthesia. Leslie R, Hardy R, Hersch P, Kelly FE. Oral presentation at SASWR meeting, Bristol 2015 SASWR trainee prize 2015. 8. Foy K. SASWR Ross Davis Adventure award to travel, work and undertake research in Zambia. 9. Avoiding harm across multidisciplinary teams by embedding a high quality checklist to prevent Never Events. Jordan L. Finalist HSJ/NT Patient Safety Care Awards July 2016 10. Improving Awareness of sepsis in the public and in primary care. Lucas E, Jordan L, Hersch E. Best poster Regional Sepsis Master class, Taunton February ‘16. 11. Improving early recognition and treatment of sepsis using an innovative campaign as well as frontline 'tea - trolley' teaching. Jordan L. Finalist HSJ/NT Patient Safety Care Awards July 2016 12. The obstetric sepsis tea- trolley. McDonald M, Jordan L. Winner best poster University of Bath/ RUH Research showcasing event June 2015 13. The ‘Phlebotomy Box’: Improving Handover within the Phlebotomy Service. Saunsbury E, Howarth G, Hotton E, Jordan L, Ward A. 3 Winner best overall poster WEAHSN Patient Safety Conference October 2015 14. Humphry Davy Medal, RCoA, 2016 Goodwin A. 15. Mushin Medal, Society of Anaesthetists of Wales, March 2017 Goodwin A. 16. Honorary Professor of resuscitation, University of Bristol, 2015 Nolan JP 17. Liaison Committee on Resuscitation (ILCOR) International Resuscitation Giant Feb 2015 (Five such awards are made internationally every 5 years) Nolan JP. 18. American Heart Association Lifetime Achievement Award November 2016. Nolan JP (In recognition of contributions to resuscitation science). 19. Honorary Professor of Anaesthesia, University of Bristol, 2015 Cook TM 20. Humphry Davy Award, Royal College of Anaesthetists 2016 Cook TM and the NAP5 team 21. Rowling Medal, Yorkshire Society of anaesthetists, March 2017. Cook TM. 22. International airway Management Society– Distinguished Research Award 2016 Cook TM 23. BMA Book awards winner: Best Anaesthesia book 2014 – 2015 Cook TM and NAP5 team 24. Irish Healthcare Awards 2015: An Duais Mhór trophy Overall winner (from all individual award winners) and Best Hospital Project; Pandit JJ, Cook TM, and on behalf of the 5th National Audit Project (NAP5) of the Royal College of Anaesthetists and the Association of Anaesthetists of Great Britain and Ireland, and the College of Anaesthetists of Ireland. Accidental awareness during general anaesthesia report and findings. http://www.irishhealthcareawards.ie/ 4 Notable bibliometrics Difficult airway management A paper in press (Anaesthesia and analgesia 2017) analyses 2015 global Difficult Airway Literature over the last 30 years The RUH dept of anaesthesia was ranked no 3 in terms of productivity (No 1 in Europe) No 3 in terms of citations (No 1 in Europe). RUH has the individual author ranked No 1 in terms of productivity and No 4 in terms of citations. BJA most cited rankings. As of November 2016. The NAP4 study is the most cited paper in BJA ever (NAP4 ICU paper no 3 and NAP3 paper no 6). All first authored from RUH. 5 Publications 2015-16 Original articles 1. Dramatic resuscitation with Intralipid in an epinephrine unresponsive cardiac arrest following overdose of amitriptyline and propranolol. Le Fevre P, Acharya K, Gosling M, Georgiou A. BMJ Case Rep 2017. doi:10.1136/bcr-2016-218281 2. Pseudo-outbreaks of Stenotrophomonas maltophilia on an intensive care unit in England. Waite TD, Georgiou A, Abrishamie M, Beck CR. J Hosp Infection. 2016: 1-5. 3. Rescuing the obese or burned airway: are conventional training manikins adequate? A simulation study. Howes T, Lobo C, Kelly FE, Cook TM. British Journal of Anaesthesia http://www.ncbi.nlm.nih.gov/pubmed/25296912 2015; 114: 136-42. doi: 10.1093/bja/aeu336. Epub 2014 Oct 8. [Accompanying editorial in March 2015 BJA by Michael Kristensen]. Also featured in Survey of Anesthesiology: 2015; 59: 219–220. doi: 10.1097/01.SA.0000470068.83390.2d 4. Macroscopic barotrauma by stiff and soft-tipped airway exchange catheters: an in vitro model. Axe R, Middleditch A, Kelly FE, Batchelor TJ, Cook TM. Anesth Analg. 2015; 120: 355-61. 5. Adopting universal testing for HIV in intensive care for patients admitted with severe pneumonia: results from our change in practice. Sharvill RJ, Fernandes A, Allen K, Astin J. International Journal of STD and AIDS 2017; 28: 88-90 6. Just Say Sepsis. Goodwin A, Srivastava V, Shotton H, Protopapa K, Butt A, Mason M.bLondon; National Confidential Enquiry into Patient Outcome and Death 2015 7. Assessment of an urgency classification for assisted vaginal delivery. Leslie RA, Kinsella SM, Astin J, Tuckey J. Journal of Obstetrics and Gynaecology 2016 DOI: 10.1080/01443615.2016.1233949 8. The acute psychobiological impact of the intensive care experience on relatives. Turner-Cobb JM, Smith PC, Ramchandani P, Begen FM, Padkin A. Psychol Health Med. 2016; 21: 20-6. 9. A Randomised tRial of Expedited transfer to a cardiac arrest centre for non-ST elevation ventricular fibrillation out-of-hospital cardiac arrest: The ARREST pilot randomised trial. Patterson T, Perkins GD, Joseph J, Wilson K, Van Dyck L, Roberston S, Nguyen H, McConkey H, Whitbread M, Fothergill R, Nevett J, Dalby M, Rakhit R, MacCarthy P, Perera D, Nolan JP, Redwood SR. Resuscitation 2017; 10. Lockey DJ, Crewdson K, Davies G, Jenkins B, Klein J, Laird C, Mahoney PF, Nolan J, Pountney A, Shinde S, Tighe S, Russell MQ, Price J, Wright C. AAGBI: Safer pre-hospital anaesthesia 2017. Anaesthesia 2017; 72: 379–390. 6 11. Anderson LW, Granfeldt A, Callaway C, Bradley SM, Soar J, Nolan JP, Kurth T, Donnino MW for the American Heart Association’s Get With The Guidelines – Resuscitation Investigators. Association between tracheal intubation during adult in-hospital cardiac arrest and survival. JAMA 2017; 317: 494–506. 12. Hawkes C, Booth S, Ji C, Brace-McDonnell SJ, Whittington A, Mapstone J, Cooke MW, Deakin CD, Gale CP, Fothergill R, Nolan JP, Rees N, Soar J, Siriwardena AN, Brown TP, Perkins GD; OHCAO collaborators. Epidemiology and outcomes from out-of-hospital cardiac arrests in England Resuscitation 2017; 110: 133–140. 13. Deakin CD, Yang J, Nguyen R, Zhu J, Brett SJ, Nolan JP, Perkins GD, Pogson DG, Parnia S. Effects of epinephrine on cerebral oxygenation during cardiopulmonary resuscitation: a prospective cohort study. Resuscitation 2016; 109: 138–44. 14. Taylor J, Black S, J Brett S, Kirby K, Nolan JP, Reeves BC, Robinson M, Rogers CA, Scott LJ, South A, Stokes EA, Thomas M, Voss S, Wordsworth S, Benger JR. Design and implementation of the AIRWAYS-2 trial: A multi-centre cluster randomised controlled trial of the clinical and cost effectiveness of the i-gel supraglottic airway device versus tracheal intubation in the initial airway management of out of hospital cardiac arrest. Resuscitation 2016; 108: 75–81. 15. Perkins GD, Quinn T, Deakin CD, Nolan JP, Lall R, Slowther AM, Cooke M, Lamb SE, Petrou S, Achana F, Finn J, Jacobs IG, Carson A, Smyth M, Han K, Byers S, Rees N, Whitfield R, Moore F, Fothergill R, Stallard N, Long J, Hennings S, Horton J, Kaye C, Gates S. Pre-hospital Assessment of the Role of Adrenaline: Measuring the Effectiveness of Drug administration In Cardiac arrest (PARAMEDIC-2): Trial protocol. Resuscitation 2016; 108: 75-81. 16. Increasing survival after admission to UK critical care units following cardiopulmonary resuscitation. Nolan JP, Ferrando P, Soar J, Benger J, Thomas M, Harrison DA, Perkins GD. Critical Care 2016;20:219 17. Cerebral Oximetry During Cardiac Arrest: A Multicenter Study of Neurologic Outcomes and Survival. Parnia S, Yang J, Nguyen R, Ahn A, Zhu J, Inigo-Santiago L, Nasir A, Golder K, Ravishankar S, Bartlett P, Xu J, Pogson D, Cooke S, Walker C, Spearpoint K, Kitson D, Melody T, Chilwan M, Schoenfeld E, Richman P, Mills B, Wichtendahl N, Nolan J, Singer A, Brett S, Perkins GD, Deakin CD. Crit Care Med. 2016; 44: 1663–74. 18. Risk-adjusted survival for adults following in-hospital cardiac arrest by day of week and time of day: observational cohort study. Robinson EJ, Smith GB, Power SG, Harrison DA, Nolan J, Soar J, Spearpoint K, Gwinnutt C, Rowan KM. BMJ Qual Saf 2016;25:832–841. 19. Randomised comparison of the effectiveness of the laryngeal mask airway supreme, i-gel, and current practice in the initial airway management of out of hospital cardiac arrest: a feasibility study. Benger J, Coates D, Davies S, Greenwood R, Nolan J, Rhys M, Thomas M, Voss S. Brit J Anaesth 2016;116:262–8. 7 20. Management of cardiac arrest survivors in UK intensive care units: a survey of practice. Ford AH, Clark T, Reynolds EC, Ross C, Shelley K, Simmonds L, Benger J, Soar J, Nolan JP, Thomas M. Journal of the Intensive Care Society 2016;17:117–121. 21. Temperature Management After Cardiac Arrest: An Advisory Statement by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation and the American Heart Association Emergency Cardiovascular Care Committee and the Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation. Donnino MW, Andersen LW, Berg KM, Reynolds JC, Nolan JP, Morley PT, Lang E, Cocchi MN, Xanthos T, Callaway CW, Soar J. Circulation 2015;132:2448–2456. Co-published in Resuscitation 2016:98:97–104. 22. European Resuscitation Council and European Society of Intensive Care Medicine 2015 Guidelines for post-resuscitation care. Nolan JP, Soar J, Cariou A, Cronberg T, Moulaert VRM, Deakin CD, Bottiger BW, Friberg H, Sunde K, Sandroni C. Intensive Care Medicine 2015; 41: 2039–56. 23. European Resuscitation Council and European Society of Intensive Care Medicine Guidelines post-resuscitation care: Section 5 of the European Resuscitation Guidelines for Resuscitation 2015. Nolan JP, Soar J, Cariou A, Cronberg T, Moulaert VRM, Deakin CD, Bottiger BW, Friberg H, Sunde K, Sandroni C. Resuscitation 2015;95:201-21. 24. Monsieurs KG, Nolan JP, Bossaert LL, Greif R, Maconochie IK, Nikolaou NI, Perkins GD, Soar J, Truhlář A, Wyllie J, Zideman DA; ERC Guidelines 2015 Writing Group. European Resuscitation Council Guidelines for Resuscitation 2015 Section 1. Executive Summary. Resuscitation 2015; 95: 1-80. 25. European Resuscitation Council Guidelines for Resuscitation 2015: Section 3. Adult Advanced Life Support. Soar J, Nolan JP, Böttiger BW, Perkins GD, Lott C, Carli P, Pellis T, Sandroni C, Skrifvars MB, Smith GB, Sunde K, Deakin CD; Adult advanced life support section Collaborators. Resuscitation 2015; 95: 100–147. 26. European Resuscitation Council Guidelines for Resuscitation 2015: Section 4. Cardiac arrest in special circumstances. Truhlář A, Deakin CD, Soar J, Khalifa GE, Alfonzo A, Bierens JJ, Brattebø G, Brugger H, Dunning J, Hunyadi-Antičević S, Koster RW, Lockey DJ, Lott C, Paal P, Perkins GD, Sandroni C, Thies KC, Zideman DA, Nolan JP; Cardiac arrest in special circumstances section Collaborators. Resuscitation 2015; 95: 148–201. 27. European Resuscitation Council Guidelines for Resuscitation 2015: Section 11. The ethics of resuscitation and end-of-life decisions. Bossaert LL, Perkins GD, Askitopoulou H, Raffay VI, Greif R, Haywood KL, Mentzelopoulos SD, Nolan JP, Van de Voorde P, Xanthos TT; ethics of resuscitation and end-of-life decisions section Collaborators. Resuscitation 2015; 95: 302–11. 28. Part I. Executive Summary: 2015 International Consensus on cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Nolan JP, Hazinski 8 MF, Aickin R, Bhanji F, Billi JE, Callaway CW, Castren M, de Caen AR, Ferrer JM, Finn JC, Gent LM, Griffin RE, Iverson S, Lang E, Lim SH, Maconochie IK, Montgomery WH, Morley PT, Nadkarni VM, Neumar RW, Nikolaou NI, Perkins GD, Perlman JM, Singletary EM, Soar J, Travers AH, Welsford M, Wyllie J, Zideman DA. Resuscitation 2015; 95: e1-e32. 29. Part I. Executive Summary: 2015 International Consensus on cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Hazinski MF, Nolan JP, Aickin R, Bhanji F, Billi JE, Callaway CW, Castren M, de Caen AR, Ferrer JM, Finn JC, Gent LM, Griffin RE, Iverson S, Lang E, Lim SH, Maconochie IK, Montgomery WH, Morley PT, Nadkarni VM, Neumar RW, Nikolaou NI, Perkins GD, Perlman JM, Singletary EM, Soar J, Travers AH, Welsford M, Wyllie J, Zideman DA. Circulation 2015; 132(16 Suppl 1): S2–S39. 30. Part 2. Evidence evaluation and management of conflicts of interest: 2015 International Consensus on cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Morley PT, Lang E, Aickin R, Billi JE, Eigel B, Ferrer JM, Finn JC, Gent LM, Griffin RE, Hazinski MF, Maconochie IK, Montgomery WH, Morrison LJ, Nadkarni VM, Nikolaou NI, Nolan JP, Perkins GD, Sayre MR, Travers AH, Wyllie J, Zideman DA. Resuscitation 2015; 95: e33–e41. 31. Part 2. Evidence evaluation and management of conflicts of interest: 2015 International Consensus on cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Morley PT, Lang E, Aickin R, Billi JE, Eigel B, Ferrer JM, Finn JC, Gent LM, Griffin RE, Hazinski MF, Maconochie IK, Montgomery WH, Morrison LJ, Nadkarni VM, Nikolaou NI, Nolan JP, Perkins GD, Sayre MR, Travers AH, Wyllie J, Zideman DA. Circulation 2015; 132(16 Suppl 1): S40–50. 32. Part 4. Advanced Life Support: 2015 International Consensus on cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Soar J, Callaway CW, Aibiki M, Böttiger BW, Brooks SC, Deakin CD, Donnino MW, Drajer S, Kloeck W, Morley PT, Morrison LJ, Neumar RW, Nicholson TC, Nolan JP, Okada K, O'Neil BJ, Paiva EF, Parr MJ, Wang TL, Witt J; Advanced Life Support Chapter Collaborators. Resuscitation 2015; 95: e71–e120. 33. Part 4. Advanced Life Support: 2015 International Consensus on cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Callaway CW, Soar J, Aibiki M, Böttiger BW, Brooks SC, Deakin CD, Donnino MW, Drajer S, Kloeck W, Morley PT, Morrison LJ, Neumar RW, Nicholson TC, Nolan JP, Okada K, O'Neil BJ, Paiva EF, Parr MJ, Wang TL, Witt J; Advanced Life Support Chapter Collaborators. Circulation 2015; 132(16 Suppl 1): S84–S145. 34. Ten strategies to increase survival of cardiac arrest patients. Cariou A, Nolan JP, Sunde K. Intensive Care Medicine 2015; 41: 1820–3. 35. Cardiac arrest and cardiopulmonary resuscitation outcome reports: update of the Utstein resuscitation registry templates for out-of-hospital cardiac arrest. A statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation 9 (American Heart Association, European Resuscitation Council, Australian and New Zealand Council On Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia). Perkins GD, Jacobs IG*, Nadkarni V, Berg RA, Bhanji F, Biarent D, Bossaert LL, Brett SJ, Chamberlain DA, de Caen AR, Deakin CD, Finn JC, Gräsner J-T, Hazinski MF, Iwami T, Koster RW, Lim SH, Huei-Ming Ma M, McNally BF, Morley PT, Morrison L, Monsieurs KG, Montgomery W, Nichol G, Okada K, Eng Hock Ong M, Travers AH, Nolan JP for the Utstein collaborators. Circulation 2015; 132: 1286–300. Co-published in Resuscitation 2015: 96: 328–40. 36. A Randomised Comparison of the ProSeal Laryngeal Mask Airway and the i-gel during Anaesthesia in a European population. Bosley N, Burrows LA, Bhayani S, Nworah E, Cook TM. Journal of Anaesthesia and Clinical Research 2014, 5: 459. doi:10.4172/2155- 6148.1000459 http://dx.doi.org/10.4172/2155-6148.1000459 37. A Randomised Comparison of the Supreme Laryngeal Mask Airway and the i-gel during Anaesthesia in a European population. Fenner L, Handel J, Nolan J, Simpson T, Cook TM. Journal of Anaesthesia and Clinical Research 2014; 5: 440. doi:10.4172/2155- 6148.1000440 http://dx.doi.org/10.4172/2155-6148.1000440 38. Huddart S, Peden CJ, Swart M, McCormick B, Dickinson M, Mohammed MA, Quiney N; ELPQuiC Collaborator Group (Collaborators (20) - Hemmings V, Riga A, Belguamkar A, Zuleika M, White D, Corrigan L, Howes T, Richards S, Dalton S, Cook T, Kryztopik R, Cornwell A, Goddard J, Grifiths S, Frost F, Pigott A, Pittman J, Cossey L, Smart N, Daniels I. Use of a pathway quality improvement care bundle to reduce mortality after emergency laparotomy. Br J Surg. 2015; 102: 57-662 doi: 10.1002/bjs.9658. 39. Axe R, Middleditch A, Kelly F, Batchelor T, Cook TM. Macroscopic lung barotrauma during oxygenation and ventilation via an Airway Exchange Catheter. A&A 2015; 120: 355–61. Podcast: http://aa2day.org/2015/02/airwayexchange/ 40. Postoperative morbidity survey, mortality and length of stay following emergency laparotomy. Howes TE, Cook TM, Corrigan LJ, Dalton SJ, Richards SK, Peden CJ. Anaesthesia 2015; 70: 1020– 27. doi: 10.1111/anae.12991. https://twitter.com/anaes_journal/status/633917043297943552 41. Litigation associated with intensive care unit treatment in England: an analysis of NHSLA data 1995–2012. Pascall E, Trehane S-J, Georgiou A, Cook TM. Br. J. Anaesth. 2015: 115; 601-7 doi:10.1093/bja/aev285 42. The state of UK pediatric anesthesia: a survey of National Health Service activity. Sury M, Arumainathan M, Belhajh AM, Palmer JHM, Cook TM, Pandit JJ. Paed anaes 2015; 25; 1085-92 43. The State of UK Dental Anaesthesia in 2013: results from the NAP5 Activity Survey. Sury M, Palmer JHMacG, Cook TM, Pandit JJ. Society for the advancement of Anaesthesia in Dentistry Digest 2016; 32: 34-6 44. The 'go-between' study: a simulation study comparing the 'Traffic Lights' and 'SBAR' tools as a means of communication between anaesthetic staff. MacDougall-Davis SR, Kettley L, Cook TM. 10
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