Vaccines And Autism: A Case Study Alison Taylor PDF
Preview Vaccines And Autism: A Case Study Alison Taylor
Vaccines and Autism: A Case Study Alison Taylor Autism • Neurological and Developmental Disorder • Autism Spectrum Disorders • Symptoms ― Language ― Social Behaviors ― Repetitive-Restrictive Behavior http://commons.wikimedia.org/wiki/File:Autism-stacking-cans_edit.jpg Incidence Rates of Autism Olmsted County, Minnesota Barbaresi et al., 2009 (Pubmed Central) Genetics and Environment: Human Disorders GENETIC MIXED ENVIRONMENTAL Sickle cell Vitamin Cancer anemia Deficiency AUTISM http://commons.wikimedia.org/wiki/File:Sicklecells4.jpg, http://commons.wikimedia.org/wiki/File:Scorbutic_tongue.jpg http://commons.wikimedia.org/wiki/File:Carcinoma_microcellulare_oatcell_carcinoma_or_anaplastic_carcinoma_%28lu ng%29H%26E_magn_200x.jpg Genetics of Autism Unrelated Siblings Fraternal Twins Identical Twins Children 4.5% 0-10% 70-90% <1% Information Source: Abrahams and Geschwind, 2008 The Beginning of the Vaccines & Autism Debate (1998) Wakefield study suggesting a correlation between receiving the MMR vaccine and displaying behavioral symptoms of autism (1999) US Public Health Service and American Academy of Pediatrics recommend removing thimerosal from vaccines as much as possible The Beginning of the Vaccines & Autism Debate (1998) Wakefield study suggesting a correlation between receiving the MMR vaccine and displaying behavioral symptoms of autism (1999) US Public Health Service and American Academy of Pediatrics recommend removing thimerosal from vaccines as much as possible MMR Vaccine – Autism Hypothesis http://commons.wikimedia.org/wiki/File:Intestine.gif Wakefield Study: Study Design • 12 children • Parents or doctors reported GI symptoms and autism near administration of MMR vaccine • Samples were taken to confirm GI symptoms Information source: Wakefield et al., 1998 Wakefield Study: Study Flaws • Small Number • Case Report • Patient Testimonial • Selection Bias • Confounding factors • Ethical Concerns • Does not prove hypothesis “We did not prove an association between measles, mumps, and rubella vaccine and the syndrome described.” Information source: Wakefield et al., 1998
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