Ultra Performance Liquid Chromatography Mass Spectrometry : Evaluation and Applications in Food Analysis.

464 Pages·2014·17.34 MB·English

by  Mu Naushad and Mohammad Rizwan Khan

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Chromatography Mass Spectrometry
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Evaluation and Applications Mass Spectrometry
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Due to its high sensitivity and selectivity, liquid chromatography–mass
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icals in a complex mixture. Ultra Performance Liquid Chromatography a
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presents a unique collection of up-to-date UPLC–MS/MS methods for ga
the separation and quantitative determination of components, contam- r Food Analysis
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inants, vitamins, and aroma and flavor compounds in a wide variety of
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The book begins with an overview of the history, principles, and
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advancement of chromatography. It discusses the use of UHPLC tech- Mm
niques in food metabolomics, approaches for analysis of foodborne aa
carcinogens, and details of UPLC–MS techniques used for the sep- sn
aration and determination of capsaicinoids. Chapters describe the sc

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analysis of contaminants in food, including pesticides, aflatoxin, per- S

fluorochemicals, and acrylamide, as well as potentially carcinogenic pL
heterocyclic amines in cooked foods. ei
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The book covers food analysis for beneficial compounds, such as tu
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the determination of folate, vitamin content analysis, applications for od
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avocado metabolite studies, virgin olive oil component analysis, lactose
determination in milk, and analysis of minor components of cocoa e
and phenolic compounds in fruits and vegetables. With contributions t
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by experts in interdisciplinary fields, this reference offers practical y
information for readers in research and development, production, and
Edited by
routing analysis of foods and food products.
Mu. Naushad
Mohammad Rizwan Khan
K20519
ISBN-13: 978-1-4665-9154-7
90000
9 781466 591547
K20519_Cover_mech.indd All Pages 2/12/14 3:09 PM
Ultra Performance
Liquid Chromatography
Mass Spectrometry
Evaluation and
Applications in
Food Analysis

Ultra Performance
Liquid Chromatography
Mass Spectrometry
Evaluation and
Applications in
Food Analysis
Edited by
Mu. Naushad
Mohammad Rizwan Khan
Boca Raton London New York
CRC Press is an imprint of the
Taylor & Francis Group, an informa business
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© 2014 by Taylor & Francis Group, LLC
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Version Date: 20140108
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Contents
Preface......................................................................................................................vii
Acknowledgment ......................................................................................................ix
Editors .......................................................................................................................xi
Contributors ...........................................................................................................xiii
Chapter 1 History and Introduction of UPLC/MS ...............................................1
Mu. Naushad, Mohammad Rizwan Khan, and
Zeid Abdullah Alothman
Chapter 2 UHPLC–MS(/MS) Analysis of Pesticides in Food ............................17
Paolo Lucci, Rosa Busquets, and Oscar Núñez
Chapter 3 Ultra-High-Performance Liquid Chromatography in Food
Metabolomics: Food Quality and Authenticity ..................................51
Cristina C. Jacob and H. Gallart-Ayala
Chapter 4 UHPLC–MS-Based Methods for the Study of Foodborne
Carcinogens ........................................................................................69
Lubinda Mbundi and Rosa Busquets
Chapter 5 Ultra-Performance Liquid Chromatography–Mass Spectrometry
for the Determination of Capsaicinoids in Capsicum Species ...........87
Saikh Mohammad Wabaidur
Chapter 6 Applications of UPLC–MS/MS for the Quantification
of Folate Vitamers ............................................................................115
Maria V. Chandra-Hioe, Jayashree Arcot, and Martin P. Bucknall
Chapter 7 UPLC–MS/MS Analysis of Heterocyclic Amines in Cooked Food ...129
Mohammad Rizwan Khan and Mu. Naushad
Chapter 8 Determination of Avocado Fruit Metabolites by UHPLC–MS:
Complementarity with Other Analytical Platforms .........................175
Elena Hurtado-Fernández, María Gómez-Romero, Tiziana
Pacchiarotta, Oleg A. Mayboroda, Alegría Carrasco-
Pancorbo, and Alberto Fernández-Gutiérrez
v
vi Contents
Chapter 9 UHPLC–MS in Virgin Olive Oil Analysis: An Evolution toward
the Rationalization and Speed of Analytical Methods ....................213
Aadil Bajoub, Alegría Carrasco-Pancorbo, Noureddine
Ouazzani, and Alberto Fernández-Gutiérrez
Chapter 10 Vitamin Analysis in Food by UPLC–MS ........................................243
Ahmad Aqel, Kareem Yusuf, Asma’a Al-Rifai, and
Zeid Abdullah Alothman
Chapter 11 UPLC–MS as an Analytical Tool for the Determination
of Aflatoxins in Food........................................................................279
Kareem Yusuf, Ahmad Aqel, Ayman Abdel Ghfar,
and Zeid Abdullah Alothman
Chapter 12 Determination of Perfluorochemicals in Food and Drinking
Water Samples Using UHPLC–MS Technique ................................307
Fabio Gosetti, Eleonora Mazzucco, Maria Carla Gennaro,
and Emilio Marengo
Chapter 13 Determination of Acrylamide in Foodstuffs Using UPLC–MS ......333
Ayman Abdel Ghfar and Ibrahim Hotan Alsohaimi
Chapter 14 Determination of Procyanidins and Alkaloids in Cocoa
and Biological Samples by Ultra-High-Performance Liquid
Chromatography Coupled to Tandem Mass Spectrometry ..............359
Alba Macià, Maria José Motilva, and Nàdia Ortega
Chapter 15 Ultra-Performance Liquid Chromatography–Mass
Spectrometry and Its Application toward the Determination
of Lactose Content in Milk ..............................................................389
Mahamudur Islam
Chapter 16 Fast and Reliable Analysis of Phenolic Compounds in Fruits
and Vegetables by UHPLC–MS .......................................................411
M. I. Alarcón-Flores, R. Romero-González, J. L. Martínez
Vidal, and A. Garrido Frenich
Preface
The development of many novel techniques that make our existence so comfortable
has been intimately associated with the accessibility of suitable analytical meth-
ods. Liquid chromatography–mass spectrometry (LC–MS) is a powerful technique
used for various applications based upon its very high sensitivity and selectivity.
Generally, its applications are oriented toward the detection and identification of
chemicals in a complex mixture. Preparative LC–MS systems can be used for fast
and mass-directed purification of natural product extracts and new molecular entities
important to food, pharmaceutical, agrochemical, and other industries.
This book presents a unique collection of up-to-date UPLC–MS/MS (ultra per-
formance liquid chromatography–tandem mass spectrometric) methods for the
separation and quantitative determination of pesticides, capsaicinoids, heterocyclic
amines, aflatoxin, perfluorochemicals, acrylamide, procyanidins and alkaloids, lac-
tose content, phenolic compounds, vitamins, and aroma and flavor compounds in a
wide variety of foods and food products.
This book is the result of the remarkable contributions of 36 experts in interdis-
ciplinary fields of science, with comprehensive, in-depth, and up-to-date research
works and reviews. Composed of 16 chapters and compiled using more than 78 fig-
ures and 50 tables, this text delivers practical information to all people involved in
the research and development, production, or routing analysis of foods and food
products.
Mu. Naushad and Mohammad Rizwan Khan
Editors
vii

Acknowledgment
We are most obligated to the elegance of the Almighty God, who inspires all of
humanity to knowledge, and who blessed us with the needed favor to complete this
work.
This book is the result of outstanding contributions from experts in the field of
ultra-performance liquid chromatography and food science, with up-to-date and
comprehensive reviews and research works. We are grateful to all of the contribut-
ing authors and their coauthors for their valued contribution to this book. We would
also like to thank all of the publishers, authors, and others who have granted us per-
mission to use their figures or tables. Sincere efforts have been made to reproduce
them and to include citations with the reproduced materials. I would still like to offer
my deep apologies to any copyright holder whose rights may have been mistakenly
overlooked.
The authors would like to extend their sincere appreciation to King Saud
University, Deanship of Scientific Research, College of Science Research Center for
its supporting of this book.
Mu. Naushad and Mohammad Rizwan Khan
Editors
ix