The Scientific Basis of Urology PDF
Preview The Scientific Basis of Urology
Cover Page i The Scientific Basis of Urology Page ii This page intentionally left blank. Page iii The Scientific Basis of Urology Second Edition Edited by Anthony R Mundy MS FRCP FRCS Professor of Urology The Institute of Urology and Nephrology London UK John M Fitzpatrick MCh FRCSI FRC(Urol) FRCSGlas FRCS Professor and Chairman Department of Surgery University College Dublin Dublin 7 Ireland David E Neal FMed Sci MS FRCS Professor of Surgical Oncology Department of Oncology Addenbrooke’s Hospital Cambridge UK Nicholas J R George MD FRCS Senior Lecturer/Consultant Urologist Department of Urology University Hospitals of South Manchester Manchester UK LONDON AND NEW YORK Page iv © 1999, 2004 Taylor & Francis, an imprint of the Taylor & Francis Group First published in the United Kingdom in 1999 by Isis Medical Media Ltd This edition published in the Taylor & Francis eLibrary, 2005. To purchase your own copy of this or any of Taylor & Francis or Routledge’s collection of thousands of eBooks please go to www.eBookstore.tandf.co.uk. Second edition published in the United Kingdom in 2004 by Taylor & Francis, an imprint of the Taylor & Francis Group, 11 New Fetter Lane, London EC4P 4EE Tel.: +44 (0) 20 7583 9855 Fax.: +44 (0) 20 7842 2298 Email: [email protected] Website: http://www.dunitz.co.uk All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior permission of the publisher or in accordance with the provisions of the Copyright, Designs and Patents Act 1988 or under the terms of any licence permitting limited copying issued by the Copyright Licensing Agency, 90 Tottenham Court Road, London W1P 0LP. Although every effort has been made to ensure that all owners of copyright material have been acknowledged in this publication, we would be glad to acknowledge in subsequent reprints or editions any omissions brought to our attention. Although every effort has been made to ensure that drug doses and other information are presented accurately in this publication, the ultimate responsibility rests with the prescribing physician. Neither the publishers nor the authors can be held responsible for errors or for any consequences arising from the use of information contained herein. For detailed prescribing information or instructions on the use of any product or procedure discussed herein, please consult the prescribing information or instructional material issued by the manufacturer. A CIP record for this book is available from the British Library. Library of Congress CataloginginPublication Data Data available on application ISBN 0203640500 Master ebook ISBN ISBN 0203693655 (OEB Format) ISBN 1 90186 513 4 (Print Edition) Distributed in North and South America by Taylor & Francis 2000 NW Corporate Blvd Boca Raton, FL 33431, USA Within Continental USA Tel.: 800 272 7737; Fax.: 800 374 3401 Outside Continental USA Tel.: 561 994 0555; Fax.: 561 361 6018 Email: [email protected] Distributed in the rest of the world by Thomson Publishing Services Cheriton House North Way Andover, Hampshire SP10 5BE, UK Tel.: +44 (0)1264 332424 Email: [email protected] Composition by J&L Composition, Filey, North Yorkshire Page v Contents List of contributors viii Preface to the first edition xii Preface to the second edition xiv 1 An introduction to cell biology 1 Anthony R Mundy 2 The cell and cell division 31 David E Neal 3 Inflammation 57 Neville Woolf 4 Immunology 67 AC Cunningham and John A Kirby 5 The nature of renal function 83 George B Haycock 6 Principles of radiological imaging of the urinary tract 117 Uday Patel 7 Upper urinary tract obstruction 129 NJ Hegarty, R William G Watson and John M Fitzpatrick 8 Interactive obstructive uropathy: Observations and conclusions from studies on humans 147 Nicholas JR George 9 Urinary tract infection 165 Nicholas JR George 10 The scientific basis of urinary stone formation 205 William G Robertson 11 Shock 229 David A Brealey and Andrew R Webb 12 Acute renal failure 245 Guy H Neild 13 Chronic renal failure 257 Guy H Neild 14 Structure and function of the lower urinary tract 265 Anthony R Mundy 15 Detrusor smooth muscle physiology 291 Christopher H Fry 16 The pathophysiology of bladder dysfunction 315 Christopher H Fry Page vi 17 The scientific basis of urodynamics 327 Michael Craggs and Sarah Knight 18 Male sexual function 343 Suks Minhas, John P Pryor and David J Ralph 19 The prostate and benign prostatic hyperplasia 367 Mark Emberton and Anthony R Mundy 20 Biology of cancer and metastasis 387 David E Neal 21 Tumour suppressor genes and oncogenes 395 David E Neal 22 The molecular genetics and pathology of renal cell carcinoma 407 Marie O’Donnell, Marie E Mathers, Eamonn R Maher and Steven C Clifford 23 Transitional cell carcinoma of the bladder 431 TR Leyshon Griffiths and J Kilian Mellon 24 Prostate cancer 449 Freddie C Hamdy, Mark I Johnson and Craig N Robson 25 Testis cancer 469 Alex Freeman and Stephen J Harland 26 Radiotherapy: Scientific principles and practical application in urological malignancies 493 Mary McCormack, Richard SD Brown and Heather A Payne 27 Principles of chemotherapy 507 Judith Gaffan and John Bridgewater 28 Embryology 521 David FM Thomas 29 Urological and biochemical aspects of transplantation biology 539 David Talbot and Naeem Soomro 30 Tissue transfer in urology 549 SN Venn and Anthony R Mundy 31 Energy sources in urology 561 Jeremy Elkabir and Ken M Anson 32 Urological instrumentation 579 Hugh N Whitfield and SK Gupta 33 Perioperative care of the urological patient 589 David W Ryan 34 Screening in urology 607 Nicholas JR George Page vii 35 The design, construction and interpretation of clinical trials 625 Julie A Morris 36 Evidencebased medicine for urologists 635 Mark Emberton Index 647 Page viii Contributors Ken M Anson MBBS FRCS MS FRCS(Urol) Consultant Urologist Department of Urology St George’s Hospital London, UK David A Brealey BSc MRCP Clinical Lecturer Bloomsbury Institute of Intensive Care Medicine University College London London, UK John A Bridgewater PhD MRCP Honorary Consultant in Medical Oncology Royal Free & University College School of Medicine University College London London, UK Richard SD Brown MRCP FRCF Department of Oncology Middlesex Hospital London, UK Steven C Clifford PhD Lecturer in Molecular Oncology Northern Institute for Cancer Research University of Newcastle upon Tyne Newcastle upon Tyne, UK Michael Craggs FRCS Professor and Director of Spiral Research Institute of Urology Royal National Orthopaedic Hospital Stanmore Middlesex London, UK AC Cunningham Sunderland Pharmacy School University of Sunderland Fleming Building Sunderland, UK Jeremy Elkabir MBBS FRCS FRCS(Urol) FEBU Consultant Urological Surgeon Northwick Park & St Mark’s Hospitals Harrow London, UK Page ix Mark Emberton FRCS FRCS(Urol) MD Institute of Urology Middlesex Hospital London, UK John M Fitzpatrick MCh FRCSI FRC(Urol) FRCSGlas FRCS Professor and Chairman Department of Surgery University College Dublin Dublin 7, Ireland Alex Freeman Department of Histopathology University College London London, UK Christopher H Fry FRCS Institute of Urology & Nephrology University College London London, UK Judith Gaffan Royal Free & University College School of Medicine University College London London, UK Nicholas J R George MD FRCS Senior Lecturer/Consultant Urologist Department of Urology University Hospital of South Manchester Manchester, UK TR Leyshon Griffiths Senior Lecturer in Urological Surgery Department of Urology Leicester General Hospital Leicester, UK Suresh K Gupta Department of Urology Wrexham Maelor Hospital Croesnewydd Road Wrexham, UK Freddie C Hamdy MD FRCSEd (Urol) Professor and Head of Urology Academic Urology Unit University of Sheffield Royal Hallamshire Hospital Sheffield, UK
Description:The list of books you might like
